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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| CTX001 NCT07901933 · Study of CTX001 in Adults With Anemia Due to Non-Dialysis-Dependent Chronic Kidn… | Maladie rénale chronique | À vérifier | Phase 1 | NOT_YET_RECRUITING | This is a Phase 1b, randomized, double-blinded, placebo-controlled study o… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:41 | Détail |
| Erythropoiesis-Stimulating Agent (ESA) NCT06901505 · To Evaluate the Efficacy of Three Times Weekly (TIW) Vadadustat Compared to Stan… | Maladie rénale chronique | À vérifier | Phase 3 | COMPLETED | This is a multi-center, randomized (1:1), open-label, active-controlled, p… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:41 | Détail |
| Ultrasound Guided Intercostobrachial Nerve Block NCT07754357 · ICBN/ESP — Ultrasound-Guided T2 Erector Spinae Plane Block Versus Intercostobrac… | Maladie rénale chronique | À vérifier | Non applicable | COMPLETED | This study aims to determine whether ultrasound guided ESP block at 2nd th… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:41 | Détail |
| Dapagliflozin NCT06610526 · A Study of Dapagliflozin in Chinese Adult Patients With Chronic Kidney Disease | Maladie rénale chronique | Ralentissement de la progression | Phase 4 | ACTIVE_NOT_RECRUITING | Recent trials have demonstrated positive renal outcomes of sodium-glucose… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:40 | Détail |
| Diuretic Tuner NCT04759274 · Diuretic Tuner Clinical Decision Support | Maladie rénale chronique | À vérifier | Non applicable | RECRUITING | This purpose of this study is to determine the effectiveness of a mobile p… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:40 | Détail |
| Empagliflozin NCT05614115 · Safety, Tolerability, and Feasibility of Empagliflozin Therapy in Dialysis-depen… | Maladie rénale chronique | À vérifier | Phase 1 | COMPLETED | The purpose of this study is to find out what effects (good and bad) the s… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:40 | Détail |
| Erythropoietin + Probiotic NCT07296146 · Probiotics Against Erythropoietin Resistance in Chronic Kidney Disease Patients. | Maladie rénale chronique | Traitement symptomatique | Phase 3 | COMPLETED | The goal of this clinical trial is to assess whether probiotic supplementa… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:40 | Détail |
| IV iron sucrose NCT07706582 · Management of Iron Deficiency Anemia in Hemodialysis Patients | Maladie rénale chronique | À vérifier | Phase 2 | ACTIVE_NOT_RECRUITING | The aim of this interventional study is to assess the effectiveness of ora… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:40 | Détail |
| Ravulizumab NCT05746559 · ARTEMIS: Ravulizumab to Protect Patients With CKD From CSA-AKI and MAKE | Maladie rénale chronique | À vérifier | Phase 3 | TERMINATED | The Polish multicentre observational (non-interventional) study aiming to… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:40 | Détail |
| Survodutide NCT06077864 · A Study to Test the Effect of Survodutide (BI 456906) on Cardiovascular Safety i… | Maladie rénale chronique | À vérifier | Phase 3 | COMPLETED | This study is for adults aged 18 years and older who have a type of fatty… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:40 | Détail |
| Transcutaneous vagus nerve stimulation (tVNS) NCT04099992 · MIND-CKD — Mindfulness in Chronic Kidney Disease | Maladie rénale chronique | À vérifier | Non applicable | COMPLETED | The goal of this clinical trial is to test the efficacy of transcutaneous… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:40 | Détail |
| Clazakizumab NCT03380962 · Clazakizumab in Highly-HLA Sensitized Patients Awaiting Renal Transplant | Maladie rénale chronique | Immunomodulation | Phase 1/2 | COMPLETED | The purpose of this study is to measure the change in high-sensitivity C-r… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:39 | Détail |
| NeoKidney NCT06024135 · FIH Caen — Safety and Efficacy Assessments of NeoKidney® in ESRD Patients Treate… | Maladie rénale chronique | À vérifier | Non applicable | COMPLETED | The goal of this clinical investigation is to asses the safety and efficac… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:39 | Détail |
| Sodium bicarbonate NCT05928936 · Neurovascular Regulation During Exercise in Humans With Chronic Kidney Disease:… | Maladie rénale chronique | À vérifier | Phase 2 | RECRUITING | Metabolic acidosis is a common problem that occurs with worsening chronic… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:39 | Détail |
| ULTRAFILTRATION NCT07637110 · DRIVE-UF — Dry Weight Reduction Intervention Via Extra Ultrafiltration | Maladie rénale chronique | À vérifier | Non applicable | RECRUITING | Type 2 cardio renal syndrome is defined by the occurrence or the exacerbat… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:39 | Détail |
| Albumin NCT07263308 · ARISE-2 — Albumin for Patients With Acute Large Vessel Occlusive Stroke Undergoi… | Accident vasculaire cérébral | À vérifier | Phase 3 | RECRUITING | This study is a prospective, multicenter, open-label, randomized controlle… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:35 | Détail |
| CardioWatch 287-2 Group NCT07899788 · CATCH-AF — CATCH AF - Atrial Fibrillation Detection in Cryptogenic Stroke | Accident vasculaire cérébral | À vérifier | Non applicable | NOT_YET_RECRUITING | Early detection of atrial fibrillation detected after stroke (AFDAS) is cr… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:35 | Détail |
| Cuffless ring-type continuous blood pressure monitor NCT07903922 · COMPASS — Continuous Blood Pressure Variability and Small Vessel Disease in Acut… | Accident vasculaire cérébral | À vérifier | À vérifier | NOT_YET_RECRUITING | This prospective observational cohort study examines whether blood pressur… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:35 | Détail |
| hypothermia NCT06109376 · COOLING — Role of Hypothermia in Endovascular Stroke Thrombectomy | Accident vasculaire cérébral | À vérifier | Non applicable | RECRUITING | Reducing or suspending the increase of the infarcted core, i.e., "freezing… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:35 | Détail |
| Metfomin NCT07899307 · Metformin in Acute Ischemic Stroke | Accident vasculaire cérébral | À vérifier | Phase 3 | NOT_YET_RECRUITING | The goal of this clinical trial is to study the efficacy of oral Metformin… À vérifier | ClinicalTrials.gov 2026-11-01 04:37:35 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effects of continuous vs. intermittent transcutaneous electrical stim… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 41866984 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source To compare the effects of two transcutaneous electrical stimulation (TES) patterns applied to the auricular branches of… | Cranio : the journal of craniomandibular practice 2026-11-08 04:38:07 | Source |
| Optimizing Percutaneous Tibial Nerve Stimulation Intensity for Overac… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42554545 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source Overactive bladder (OAB) is a significant global health issue. The standard percutaneous tibial nerve stimulation (PTNS… | Neuromodulation : journal of the International Neuromo… 2026-11-08 04:38:07 | Source |
| Transcutaneous auricular vagus nerve stimulation improves dysautonomi… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42802247 | Maladie rénale chronique | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Autonomic nervous system dysfunction is highly prevalent in hypermobile Ehlers-Danlos syndrome (hEDS) and contributes s… | Neurological sciences : official journal of the Italia… 2026-11-08 04:38:07 | Source |
| Factors associated with high-flow therapy failure in COVID-19-related… Non-Invasive Positive Pressure Ventilation · PMID 42888091 | Maladie rénale chronique | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source The optimal selection of non-invasive respiratory support for patients with COVID-19-related acute hypoxemic respirator… | Enfermedades infecciosas y microbiologia clinica (Engl… 2026-11-08 04:38:06 | Source |
| High-Flow Nasal Cannula in Adult Acute Care: Physiological Mechanisms… Non-Invasive Positive Pressure Ventilation · PMID 42942512 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source High-flow nasal cannula (HFNC) oxygen therapy is widely used in emergency, intensive care, perioperative, and procedura… | Medicina (Kaunas, Lithuania) 2026-11-08 04:38:06 | Source |
| Impact of respiratory support on time to achieve full oral feeding in… Non-Invasive Positive Pressure Ventilation · PMID 42871336 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source Very low birth weight infants often require respiratory support, which may delay full oral feeding. The independent rol… | Frontiers in pediatrics 2026-11-08 04:38:06 | Source |
| A comparative analysis of 3MAX aspiration versus 3 mm Trevo Retriever… Thromboaspiration catheter · PMID 31243066 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Although aspiration and stent retriever thrombectomy perform similarly in proximal occlusions, no comparative series ar… | Journal of neurointerventional surgery 2026-11-08 04:38:02 | Source |
| Percutaneous Pulmonary Thrombectomy Beyond Acute Pulmonary Embolism:… Thromboaspiration catheter · PMID 38385241 | Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Subacute massive pulmonary embolism is an uncommon manifestation of severe pulmonary embolism associated with poor prog… | Journal of endovascular therapy : an official journal… 2026-11-08 04:38:02 | Source |
| Simplified classification of cavernous internal carotid artery tortuo… Thromboaspiration catheter · PMID 35475775 | Hypertension artérielle · Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Thromboaspiration catheters are increasingly used for the endovascular treatment of large vessel stroke (LVS), while to… | Neurological research 2026-11-08 04:38:02 | Source |
| Multifocal continuous theta burst stimulation in idiopathic generaliz… Continuous Theta Burst Stimulation (cTBS) · PMID 42731195 | Accident vasculaire cérébral | Traitement symptomatique | Publication | PubMed | Voir la publication source Idiopathic generalized epilepsy (IGE) is a disorder of the cortico-subcortical networks. Continuous theta burst stimula… | Clinical neurophysiology : official journal of the Int… 2026-11-08 04:38:00 | Source |
| Optimizing brain functional-structural architecture with cTBS to redu… Continuous Theta Burst Stimulation (cTBS) · PMID 42457860 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Alcohol use disorder (AUD) is characterized by high relapse rates, necessitating novel interventions. Continuous theta-… | Molecular psychiatry 2026-11-08 04:38:00 | Source |
| Digital Outreach to Improve Statin Refills in Patients With Low Stati… Cordio System · PMID 42667613 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Statin nonadherence is a leading, addressable driver of preventable cardiovascular events. Although health systems rout… | JAMA 2026-11-08 04:37:54 | Source |
| Endovascular ablation of the right greater splanchnic nerve for the m… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42257781 | Insuffisance cardiaque | Traitement symptomatique | Publication | PubMed | Voir la publication source Heart failure with preserved ejection fraction (HFpEF) remains difficult to manage because conventional therapies often… | The Egyptian heart journal : (EHJ) : official bulletin… 2026-11-08 04:37:54 | Source |
| Incidence, medical therapy, and outcomes in heart failure with improv… Cordio System · PMID 42702264 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source To assess the incidence of heart failure with improved ejection fraction (HFimpEF) across guideline definitions (ACC/AH… | American heart journal 2026-11-08 04:37:54 | Source |
| Relationship Between the Azygos Vein and the Greater Splanchnic Nerve… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42249803 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Although ablation of the greater splanchnic nerve is now being used to treat some patients with heart failure, the anat… | Clinical anatomy (New York, N.Y.) 2026-11-08 04:37:54 | Source |
| Validation of the PREVENT-HF Risk Prediction Equation in US Veterans. Cordio System · PMID 42969140 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Circulation 2026-11-08 04:37:54 | Source |
| Changes in right ventricular-pulmonary artery coupling after transcat… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42822601 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Right ventricular-pulmonary artery (RV-PA) coupling is an established marker of prognosis in mitral regurgitation (MR),… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Intraprocedural evaluation of residual mitral and tricuspid regurgita… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42982241 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Transcatheter edge-to-edge repair (TEER) has emerged as an established therapeutic option for selected patients with se… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Tricuspid transcatheter edge-to-edge repair versus transcatheter tric… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42989943 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Recent clinical studies of tricuspid transcatheter edge-to-edge repair (T-TEER) and transcatheter tricuspid valve repla… | Current opinion in cardiology 2026-11-08 04:37:47 | Source |
| Automated Production of Gene-Edited CAR-T Cells for People Living wit… RAPA-501 Autologous T stem cells · PMID 42847201 | Cancer | Thérapie cellulaire · Thérapie génique | Publication | PubMed | Voir la publication source Adoptive transfer of gene-modified autologous T cells, for example, expressing chimeric antigen receptors (CARs), is a… | Human gene therapy 2026-11-08 04:37:39 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||