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Toutes les maladies
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Périmètre
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8666 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 4050
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Dapirolizumab pegol NCT04976322 · A Study to Evaluate the Safety and Tolerability of Dapirolizumab Pegol in Study… | Lupus | À vérifier | Phase 3 | ENROLLING_BY_INVITATION | The purpose of this study is to evaluate long-term safety and tolerability… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:57 | Détail |
| ICG318, BCMA-CD19-IL-15/IL-15 sushi Compound CAR T following lymphode… NCT07328581 · A Phase IIa Study of ICG318 CAR-T in Refractory Systemic Lupus Erythematosus Wit… | Lupus | Thérapie cellulaire | Phase 2 | RECRUITING | This Phase IIa, open-label, single-arm study includes an initial Safety Ru… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:57 | Détail |
| SG301 SC Injection NCT07447986 · To Evaluate the Efficacy and Safety of SG301 SC Injection in Systemic Lupus Eryt… | Lupus | À vérifier | Phase 2 | RECRUITING | This is a randomized, double-blind, placebo-controlled phase I clinical st… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:57 | Détail |
| SNC116 NCT07748156 · SNC116 Therapy for Refractory Systemic Lupus Erythematosus | Lupus | À vérifier | Phase 1 | NOT_YET_RECRUITING | This study aims to evaluate the safety and tolerability of SNC116 in treat… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:57 | Détail |
| High-intensity focused ultrasound NCT03927924 · High-intensity Focused Ultrasound Study | Cancer | Ralentissement de la progression | Non applicable | TERMINATED | Conventional treatment options for localized prostate cancer include prost… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:55 | Détail |
| High Intensity Focused Ultrasound (HIFU) to the Breast Cancer NCT05350059 · The HIFUB Study (HIFU in Breast Cancer) | Cancer | À vérifier | Non applicable | UNKNOWN | High Intensity Focused Ultrasound (HIFU) is a new method of treating solid… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:55 | Détail |
| Radio-Frequency Ablation (RFA) ENCAGE™ NCT01423006 · Pilot Study on Focal Prostate Radio-Frequency Ablation | Cancer | À vérifier | Non applicable | COMPLETED | This is a prospective pilot study. The purpose of this research study is t… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:55 | Détail |
| CT-guided percutaneous radiofrequency ablation NCT02629978 · Radiofrequency Ablation of Malignant Pulmonary Nodules | Cancer | À vérifier | Non applicable | UNKNOWN | The objective of this study is to evaluate the outcomes of radiofrequency… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:54 | Détail |
| EUS-guided RFA NCT03218345 · EUS-guided RFA for Pancreatic Neoplasms | Cancer | À vérifier | Non applicable | RECRUITING | Radiofrequency ablation has been used for treatment of solid neoplasms of… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:54 | Détail |
| Focal Therapy for Prostate Cancer NCT06491056 · Prospective Asian Multicenter Prostate Cancer Focal Therapy Study (ProAMFocal) | Cancer | Thérapie génique | À vérifier | RECRUITING | Whole gland therapy (radical prostatectomy and radiotherapy) has been the… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:54 | Détail |
| HIFU treatment NCT04853914 · Evaluation of the Safety of the Treatment of Benign Prostatic Hyperplasia by Hig… | Cancer | À vérifier | Non applicable | COMPLETED | Prostate adenoma or benign prostatic hypertrophy (BPH) is a benign disease… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:54 | Détail |
| Laser Therapy NCT05452668 · Laser Therapy Effect on Oral Mucositis in Childhood Acute Lymphoblastic Leukemia… | Cancer | Traitement symptomatique | Non applicable | UNKNOWN | Introduction: Oral mucositis is one of the most frequent complications ass… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:54 | Détail |
| Magnetic Resonance Image-guided High Intensity Focused Ultrasound (MR… NCT01964677 · MR-HIFU for Bone Metastases | Cancer | Traitement symptomatique | Non applicable | COMPLETED | The aim of this study is to evaluate effectiveness of the Philips Sonallev… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:54 | Détail |
| Nanoknife Irreversible Electroporation NCT03614910 · Ablation of Unresectable Locally Advanced Pancreatic Cancer With Irreversible El… | Cancer | Ralentissement de la progression · Traitement symptomatique · Thérapie génique | À vérifier | COMPLETED | Patients with pancreatic ductal adenocarcinoma will be screened by pancrea… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:54 | Détail |
| AMO959 NCT07226986 · A Phase Ib/II Open-label Study of AMO959 With Lutetium (177Lu) Vipivotide Tetrax… | Cancer | À vérifier | Phase 1/2 | RECRUITING | The purpose of this phase Ib/II study is to (a) in Phase Ib evaluate the s… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:53 | Détail |
| BI 4060107 NCT07827144 · A Study to Test How Well Different Doses of BI 4060107 Are Tolerated by People W… | Cancer | À vérifier | Phase 1 | NOT_YET_RECRUITING | This study is open to adults with advanced cancer who have selected types… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:53 | Détail |
| ES2B-C001 NCT06746688 · A First-in-human, Clinical Trial Assessing the Safety of ES2B-C001-S01 With or W… | Cancer | À vérifier | Phase 1 | ACTIVE_NOT_RECRUITING | The trial is a first-in-human, phase I, open-label, dose-escalating trial… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:53 | Détail |
| fluorouracil NCT03776487 · Nivolumab, Ipilimumab and Chemoradiation in Treating Patients With Resectable Ga… | Cancer | À vérifier | Phase 2 | ACTIVE_NOT_RECRUITING | This phase II trial studies nab-paclitaxel (paclitaxel albumin-stabilized… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:53 | Détail |
| Histotripsie — HistoSonics Edison System NCT07044362 · Histotripsy Plus Chemotherapy vs Chemotherapy Alone for Advanced Colorectal Live… | Cancer | À vérifier | Non applicable | RECRUITING | Ultrasons focalisés produisant une cavitation contrôlée et une destruction… HOPE4LIVER a rapporté un succès technique dans 95 % des tumeurs évaluées et des complications majeures liées à la procé… | ClinicalTrials.gov 2026-09-20 04:36:53 | Détail |
| Immunotherapy NCT05863052 · Analyzing Clinical Outcomes and Genomic Data of American Indian Patient Populati… | Cancer | À vérifier | À vérifier | ACTIVE_NOT_RECRUITING | The aim of this study is to describe the outcomes in American Indian patie… À vérifier | ClinicalTrials.gov 2026-09-20 04:36:53 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4595
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effects of testosterone-augmented multimodal exercise intervention in… Whole-body Electrical Muscle Stimulation Exercise · PMID 41988780 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Spinal cord injury (SCI) leads to profound muscle atrophy, aerobic deconditioning, and metabolic dysfunction. Exercise-… | The Journal of clinical endocrinology and metabolism 2026-09-20 04:37:05 | Source |
| Feasibility and acceptability of whole-body electromyostimulation in… Whole-body Electrical Muscle Stimulation Exercise · PMID 42464389 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Evidence on the effectiveness of electromyostimulation (EMS) has been reported in pulmonary rehabilitation, but the ben… | Pilot and feasibility studies 2026-09-20 04:37:05 | Source |
| Vestibular contributions adapt to the balance strategies adopted duri… Whole-body Electrical Muscle Stimulation Exercise · PMID 42616645 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Vestibular contributions during walking are not uniform, but vary with gait phase, muscle group, and balance demands. M… | Journal of neurophysiology 2026-09-20 04:37:05 | Source |
| Clinical efficacy of abdominal moxibustion at the Zhongji (CV3) in co… Yangyin Roujin Decoction · PMID 42015783 | Myopathies | Neuroprotection · Traitement symptomatique | Publication | PubMed | Voir la publication source To investigate the clinical effect of abdominal moxibustion at the Zhongji (CV3) combined with Yiqi Tonglin Yangyin dec… | Journal of traditional Chinese medicine = Chung i tsa… 2026-09-20 04:37:03 | Source |
| Yiqi Huoxue Yangyin Decoction Ameliorates Diabetic Nephropathy by Tar… Yangyin Roujin Decoction · PMID 42713045 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source This study aimed to investigate the protective effects and underlying mechanisms of Yiqi Huoxue Yangyin Decoction (YHY)… | Diabetes, metabolic syndrome and obesity : targets and… 2026-09-20 04:37:03 | Source |
| Yiqi Huoxue Yangyin Decoction attenuates diabetic nephropathy in mice… Yangyin Roujin Decoction · PMID 42016924 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Diabetic nephropathy (DN) is a major complication of diabetes with limited therapeutic options. Yiqi Huoxue Yangyin Dec… | Frontiers in pharmacology 2026-09-20 04:37:03 | Source |
| Barcoded oligonucleotide system (BOLT) for targeted organ delivery. Immunotherapy · PMID 42733790 | Cancer | À vérifier | Publication | PubMed | Voir la publication source The therapeutic potential of oligonucleotides (oligos) is limited by insufficient delivery to extrahepatic tissues. In… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Dual metabolic checkpoint blockade a 3D-Printed metalloplatform remod… Immunotherapy · PMID 42724565 | Cancer | Immunomodulation | Publication | PubMed | Voir la publication source The immunosuppressive tumor microenvironment limits the efficacy of therapies that target metabolism. Here we show a st… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Oligosaccharide adjuvant-deferred antigen endocytosis promotes cross-… Immunotherapy · PMID 42751513 | Cancer | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Antigen cross-presentation by dendritic cells (DCs) is essential for inducing cytotoxic immune responses, which are cru… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Feasibility and safety of early discharge after robot-assisted uro-on… Digital care pathway for hypertension · PMID 42671715 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Early discharge after robot-assisted uro-oncologic surgery remains limited by concerns regarding patient safety and the… | Journal of robotic surgery 2026-09-20 04:36:49 | Source |
| HomeSafe: Postpartum Hypertensive Care Enabled by Electronic Health R… Digital care pathway for hypertension · PMID 41707683 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source The objective is to present stepwise refinements to , an Epic-tethered, population-health-coordinated postpartum pathwa… | American journal of perinatology 2026-09-20 04:36:49 | Source |
| Nutraceutical and functional food: efficacy against metabolic disorde… Digital care pathway for hypertension · PMID 42603698 | Hypertension artérielle | Neuroprotection · Immunomodulation | Publication | PubMed | Voir la publication source The growing global emphasis on health consciousness has significantly increased demand for traditional and complementar… | Journal of advanced research 2026-09-20 04:36:49 | Source |
| Community-engaged design of a virtual diabetes prevention program int… Asynchronous communication with nurse · PMID 42288862 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source The Diabetes Prevention Program (DPP) is an evidence-based approach to prevent Type 2 Diabetes (T2D), the leading cause… | BMC health services research 2026-09-20 04:36:48 | Source |
| Evolving Lung Cancer Navigator Practice Through Targeted Professional… Asynchronous communication with nurse · PMID 42463006 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Lung cancer remains the leading cause of cancer deaths worldwide, and it has persistent disparities in detection, treat… | Chest 2026-09-20 04:36:48 | Source |
| Mass casualty training for prehospital and emergency providers in Kig… Asynchronous communication with nurse · PMID 42751142 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source A mass casualty incident (MCI) occurs when the number of patients exceeds available healthcare resources, placing signi… | African journal of emergency medicine : Revue africain… 2026-09-20 04:36:48 | Source |
| Innovating a Teach-Back Model for Community Health Workers Led Health… Health Literacy Project · PMID 40194526 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source From 2021 to 2023, the City of Albuquerque, the University of New Mexico (UNM) Office for Community Health, the UNM Hos… | Health literacy research and practice 2026-09-20 04:36:34 | Source |
| Carotid intima-media thickness may be an early biomarker for cardiova… Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 41026111 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source To assess early signs of atherosclerosis following long-term treatment with the ketogenic diet therapy due to concerns… | Epilepsia open 2026-09-20 04:36:33 | Source |
| Impact of low-carbohydrate diet on health status: an umbrella review. Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 39385794 | Cancer | À vérifier | Publication | PubMed | Voir la publication source The prevalence of diet-related non-communicable diseases has increased. A low-carbohydrate diet (LCDs) is one of the mo… | Frontiers in nutrition 2026-09-20 04:36:33 | Source |
| The effect of anti-seizure medications on lipid values in adults with… Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 37244221 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Certain anti-seizure medications (ASMs) adversely impact lipid values. Here, we explored the impact of ASMs on lipid va… | Epilepsy & behavior : E&B 2026-09-20 04:36:33 | Source |
| Possible role of locus coeruleus neuronal loss in age-related memory… The Role of the Locus Coeruleus in Age-related Distractibility · PMID 37694113 | Maladie d’Alzheimer | Immunomodulation | Publication | PubMed | Voir la publication source Aging is associated with a decline in cognitive abilities, including memory and attention. It is generally accepted tha… | Frontiers in neuroscience 2026-09-20 04:36:30 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||