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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Amlodipine NCT07075965 · CAP DM1 — Calcium Channel Blocker in Myotonic Dystrophy Type 1 | Myopathies | À vérifier | Phase 1 | NOT_YET_RECRUITING | The purpose of this study is to evaluate the effectiveness and mechanism o… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| Milnacipran NCT01747044 · Prospective Study of the Influence of the Diffuse Noxious Inhibitory Controls of… | Myopathies | Traitement symptomatique | Phase 2 | COMPLETED | Fibromyalgia affects 0.7 to 3.3% of the adult population and 7-10 times mo… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| Multimodal physiotherapy program NCT07577687 · Effect of Emg-Biofeedback and Multimodal Exercise on Temporomandibular Joint Dys… | Myopathies | Ralentissement de la progression · Traitement symptomatique | Non applicable | RECRUITING | Temporomandibular joint dysfunction (TMD) is a multifactorial musculoskele… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| Sodium hyaluronate with mannitol (Ostenil Tendon) NCT03984955 · CITTE — Comparing Injection Treatments for Tennis Elbow | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | Tennis elbow is one of the most common musculoskeletal problems affecting… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| KP104 NCT05504187 · Study to Evaluate Safety, Tolerability and Pharmacodynamics of KP104 in Particip… | Lupus | À vérifier | Phase 2 | WITHDRAWN | This study will evaluate the safety, tolerability, pharmacokinetics (PK),… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:57 | Détail |
| Biospecimen Collection NCT06306638 · Interstitial Photodynamic Therapy Following Palliative Radiotherapy in Treating… | Cancer | À vérifier | Phase 1/2 | RECRUITING | This phase III trial compares standard of care hormone therapy plus riboci… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:56 | Détail |
| ExAblate MRgFUS NCT01833806 · A Phase IV Post Approval Clinical Study of ExAblate Treatment of Metastatic Bone… | Cancer | Traitement symptomatique | Non applicable | COMPLETED | The study hypotheses is that the proportion of patients experiencing clini… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:56 | Détail |
| Focal Therapy NCT07623941 · CUIMC Focal Therapy Registry | Cancer | Ralentissement de la progression · Thérapie génique | À vérifier | RECRUITING | The principal aim of the registry is to collect data on focal therapy (FT)… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:56 | Détail |
| Irreversible Electroporation (IRE) NCT03484299 · Chemotherapy and Irreversible Electroporation in the Treatment of Advanced Pancr… | Cancer | À vérifier | Phase 1 | RECRUITING | Most prostate cancer treatment research in the last decade has been focuse… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:56 | Détail |
| TC-3 hydrogel NCT01799499 · NMIBC TURBT HG — A Prospective Open Label Comparative Dose Ranging Study Evaluat… | Cancer | Traitement symptomatique | Non applicable | WITHDRAWN | This study is a prospective randomized open labeled dose ranging comparati… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:56 | Détail |
| Histotripsie — HistoSonics Edison System NCT07873619 · Histotripsy for Peritoneal Tumour and Lymph Node: a Pilot Study | Cancer | À vérifier | Non applicable | NOT_YET_RECRUITING | Ultrasons focalisés produisant une cavitation contrôlée et une destruction… HOPE4LIVER a rapporté un succès technique dans 95 % des tumeurs évaluées et des complications majeures liées à la procé… | ClinicalTrials.gov 2026-11-09 21:02:55 | Détail |
| IRE by stunning pulse therapy device NCT07263451 · Safety and Feasibility of IRE for Early-stage Breast Cancer: a Prospective, Open… | Cancer | À vérifier | Non applicable | RECRUITING | This is a prospective, open-label, single-arm, exploratory clinical trial… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:55 | Détail |
| NovaSure ablation NCT05856838 · RAMBOS — NovaSure Study: Endometrial Ablation in Women With Heavy Menstrual Blee… | Cancer | Immunomodulation · Traitement symptomatique · Thérapie génique | Non applicable | RECRUITING | Heavy menstrual bleeding (HMB) affects 30% of women worldwide. It negative… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:55 | Détail |
| Zero Ischemia Robot-Assisted Laparoscopic Microwave Ablation Assisted… NCT06715878 · Zero Ischemia Robot-Assisted MWA Assisted Suture-less Tumor Enucleation of RCC W… | Cancer | À vérifier | Non applicable | RECRUITING | Zero ischemia laparoscopic radio frequency ablation assisted tumor enuclea… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:55 | Détail |
| Vaccines, Peptide NCT06252584 · AML-VAC-XS15 — Multi-peptide Vaccination Adjuvanted With XS15 in Acute Myeloid L… | Cancer | À vérifier | Phase 1 | RECRUITING | The aim of this Phase I study is to evaluate the immunogenicity along with… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:54 | Détail |
| Venetoclax NCT03223610 · Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapse… | Cancer | Thérapie cellulaire · Thérapie génique | Phase 1/2 | RECRUITING | This study evaluates the effectiveness and safety of a new conditioning re… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:54 | Détail |
| ADI-PEG 20 (Arginine deiminase pegylated) NCT07389278 · Combination ADI-PEG 20, TMZ, and RT for Treatment of Newly Diagnosed High-grade… | Cancer | À vérifier | Phase 1/2 | NOT_YET_RECRUITING | This is an open label, intra-patient dose escalation, to evaluate ADI-PEG… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:53 | Détail |
| Anti-VEGF Monoclonal Antibody NCT07504588 · Sacituzumab Govitecan With Bevacizumab Compared to Usual Chemotherapy (Carboplat… | Cancer | À vérifier | Phase 2 | RECRUITING | This phase II trial compares the effect of sacituzumab govitecan and bevac… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:53 | Détail |
| Atezolizumab NCT06096779 · Kirros — A Study Evaluating Atezolizumab, With or Without Bevacizumab, in Partic… | Cancer | À vérifier | Phase 2 | ACTIVE_NOT_RECRUITING | This phase III trial compares the effect of atezolizumab (or atezolizumab… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:53 | Détail |
| Biospecimen Collection NCT06260033 · Stereotactic Body Radiation Therapy and FES PET/CT Imaging for the Treatment of… | Cancer | À vérifier | Phase 2 | RECRUITING | This phase III trial compares standard of care hormone therapy plus riboci… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:53 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effects of continuous vs. intermittent transcutaneous electrical stim… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 41866984 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source To compare the effects of two transcutaneous electrical stimulation (TES) patterns applied to the auricular branches of… | Cranio : the journal of craniomandibular practice 2026-11-08 04:38:07 | Source |
| Optimizing Percutaneous Tibial Nerve Stimulation Intensity for Overac… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42554545 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source Overactive bladder (OAB) is a significant global health issue. The standard percutaneous tibial nerve stimulation (PTNS… | Neuromodulation : journal of the International Neuromo… 2026-11-08 04:38:07 | Source |
| Transcutaneous auricular vagus nerve stimulation improves dysautonomi… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42802247 | Maladie rénale chronique | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Autonomic nervous system dysfunction is highly prevalent in hypermobile Ehlers-Danlos syndrome (hEDS) and contributes s… | Neurological sciences : official journal of the Italia… 2026-11-08 04:38:07 | Source |
| Factors associated with high-flow therapy failure in COVID-19-related… Non-Invasive Positive Pressure Ventilation · PMID 42888091 | Maladie rénale chronique | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source The optimal selection of non-invasive respiratory support for patients with COVID-19-related acute hypoxemic respirator… | Enfermedades infecciosas y microbiologia clinica (Engl… 2026-11-08 04:38:06 | Source |
| High-Flow Nasal Cannula in Adult Acute Care: Physiological Mechanisms… Non-Invasive Positive Pressure Ventilation · PMID 42942512 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source High-flow nasal cannula (HFNC) oxygen therapy is widely used in emergency, intensive care, perioperative, and procedura… | Medicina (Kaunas, Lithuania) 2026-11-08 04:38:06 | Source |
| Impact of respiratory support on time to achieve full oral feeding in… Non-Invasive Positive Pressure Ventilation · PMID 42871336 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source Very low birth weight infants often require respiratory support, which may delay full oral feeding. The independent rol… | Frontiers in pediatrics 2026-11-08 04:38:06 | Source |
| A comparative analysis of 3MAX aspiration versus 3 mm Trevo Retriever… Thromboaspiration catheter · PMID 31243066 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Although aspiration and stent retriever thrombectomy perform similarly in proximal occlusions, no comparative series ar… | Journal of neurointerventional surgery 2026-11-08 04:38:02 | Source |
| Percutaneous Pulmonary Thrombectomy Beyond Acute Pulmonary Embolism:… Thromboaspiration catheter · PMID 38385241 | Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Subacute massive pulmonary embolism is an uncommon manifestation of severe pulmonary embolism associated with poor prog… | Journal of endovascular therapy : an official journal… 2026-11-08 04:38:02 | Source |
| Simplified classification of cavernous internal carotid artery tortuo… Thromboaspiration catheter · PMID 35475775 | Hypertension artérielle · Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Thromboaspiration catheters are increasingly used for the endovascular treatment of large vessel stroke (LVS), while to… | Neurological research 2026-11-08 04:38:02 | Source |
| Multifocal continuous theta burst stimulation in idiopathic generaliz… Continuous Theta Burst Stimulation (cTBS) · PMID 42731195 | Accident vasculaire cérébral | Traitement symptomatique | Publication | PubMed | Voir la publication source Idiopathic generalized epilepsy (IGE) is a disorder of the cortico-subcortical networks. Continuous theta burst stimula… | Clinical neurophysiology : official journal of the Int… 2026-11-08 04:38:00 | Source |
| Optimizing brain functional-structural architecture with cTBS to redu… Continuous Theta Burst Stimulation (cTBS) · PMID 42457860 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Alcohol use disorder (AUD) is characterized by high relapse rates, necessitating novel interventions. Continuous theta-… | Molecular psychiatry 2026-11-08 04:38:00 | Source |
| Digital Outreach to Improve Statin Refills in Patients With Low Stati… Cordio System · PMID 42667613 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Statin nonadherence is a leading, addressable driver of preventable cardiovascular events. Although health systems rout… | JAMA 2026-11-08 04:37:54 | Source |
| Endovascular ablation of the right greater splanchnic nerve for the m… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42257781 | Insuffisance cardiaque | Traitement symptomatique | Publication | PubMed | Voir la publication source Heart failure with preserved ejection fraction (HFpEF) remains difficult to manage because conventional therapies often… | The Egyptian heart journal : (EHJ) : official bulletin… 2026-11-08 04:37:54 | Source |
| Incidence, medical therapy, and outcomes in heart failure with improv… Cordio System · PMID 42702264 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source To assess the incidence of heart failure with improved ejection fraction (HFimpEF) across guideline definitions (ACC/AH… | American heart journal 2026-11-08 04:37:54 | Source |
| Relationship Between the Azygos Vein and the Greater Splanchnic Nerve… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42249803 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Although ablation of the greater splanchnic nerve is now being used to treat some patients with heart failure, the anat… | Clinical anatomy (New York, N.Y.) 2026-11-08 04:37:54 | Source |
| Validation of the PREVENT-HF Risk Prediction Equation in US Veterans. Cordio System · PMID 42969140 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Circulation 2026-11-08 04:37:54 | Source |
| Changes in right ventricular-pulmonary artery coupling after transcat… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42822601 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Right ventricular-pulmonary artery (RV-PA) coupling is an established marker of prognosis in mitral regurgitation (MR),… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Intraprocedural evaluation of residual mitral and tricuspid regurgita… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42982241 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Transcatheter edge-to-edge repair (TEER) has emerged as an established therapeutic option for selected patients with se… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Tricuspid transcatheter edge-to-edge repair versus transcatheter tric… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42989943 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Recent clinical studies of tricuspid transcatheter edge-to-edge repair (T-TEER) and transcatheter tricuspid valve repla… | Current opinion in cardiology 2026-11-08 04:37:47 | Source |
| Automated Production of Gene-Edited CAR-T Cells for People Living wit… RAPA-501 Autologous T stem cells · PMID 42847201 | Cancer | Thérapie cellulaire · Thérapie génique | Publication | PubMed | Voir la publication source Adoptive transfer of gene-modified autologous T cells, for example, expressing chimeric antigen receptors (CARs), is a… | Human gene therapy 2026-11-08 04:37:39 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||