Vue transversale de la maladie
Myopathies
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
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1200 résultats correspondants
· 46 visibles sur cette page
dans le périmètre Myopathies
Niveau clinique
Études et traitements 550
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| Amlodipine NCT07075965 · CAP DM1 — Calcium Channel Blocker in Myotonic Dystrophy Type 1 | Myopathies | À vérifier | Phase 1 | NOT_YET_RECRUITING | The purpose of this study is to evaluate the effectiveness and mechanism o… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| Milnacipran NCT01747044 · Prospective Study of the Influence of the Diffuse Noxious Inhibitory Controls of… | Myopathies | Traitement symptomatique | Phase 2 | COMPLETED | Fibromyalgia affects 0.7 to 3.3% of the adult population and 7-10 times mo… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| Multimodal physiotherapy program NCT07577687 · Effect of Emg-Biofeedback and Multimodal Exercise on Temporomandibular Joint Dys… | Myopathies | Ralentissement de la progression · Traitement symptomatique | Non applicable | RECRUITING | Temporomandibular joint dysfunction (TMD) is a multifactorial musculoskele… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| Sodium hyaluronate with mannitol (Ostenil Tendon) NCT03984955 · CITTE — Comparing Injection Treatments for Tennis Elbow | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | Tennis elbow is one of the most common musculoskeletal problems affecting… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| Eteplirsen NCT06606340 · EVOLVE — A Long-term Observational Study Evaluating Eteplirsen, Golodirsen, or C… | Myopathies | À vérifier | À vérifier | ENROLLING_BY_INVITATION | This is a phase 4, multicenter, prospective, observational study designed… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:15 | Détail |
| KER-065 NCT07704099 · Safety and Efficacy of KER-065 in Participants With Duchenne Muscular Dystrophy | Myopathies | À vérifier | Phase 2 | RECRUITING | The purpose of this study is to evaluate the safety, tolerability, pharmac… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:15 | Détail |
| Tegacorat NCT07911995 · A Phase 2 Trial to Investigate the Efficacy, Safety, Tolerability, Pharmacokinet… | Myopathies | À vérifier | Phase 2 | NOT_YET_RECRUITING | This Phase 2 clinical trial will evaluate the efficacy, safety, tolerabili… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:15 | Détail |
| delandistrogene moxeparvovec NCT06241950 · A Gene Transfer Therapy Study to Evaluate the Safety and Efficacy of Delandistro… | Myopathies | À vérifier | Phase 1 | TERMINATED | This open-label, single-arm study will evaluate the safety and expression… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| Exopulse Mollii Suit NCT07459361 · Acute Effects of Wearable Electrical Stimulation in Stroke | Myopathies | Traitement symptomatique | Non applicable | COMPLETED | Cerebral Palsy (CP) is is estimated to be around 1.5-3 per live birth, wit… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| Instrument Assisted Soft Tissue Mobilization NCT07921784 · Effects of IASTM, Deep Friction Massage, and Sham Instrument-Assisted Soft Tissu… | Myopathies | Ralentissement de la progression · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Background: Non-specific low back pain is a leading cause of global disabi… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| ITB Titration Protocol NCT06606574 · PREDICT-ITB — Intrathecal Baclofen and Pediatric Dystonia | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | The goal of this study is to better understand outcomes in children with d… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| Nanopulsed Electromagnetic Field Therapy (SIS) NCT07550543 · PEMF Therapy in Shoulder Tendinopathy | Myopathies | Traitement symptomatique | Non applicable | COMPLETED | The goal of this clinical trial is to evaluate whether pulsed electromagne… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| nVNS Treatment NCT07288411 · Effects of Vagus Nerve Stimulation on Temporomandibular Disorders. | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | The study aims to examine the effects of transcutaneous non-invasive vagus… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| SPOT-03 NCT07188012 · Safety and Dystrophin Expression of SPOT-03 in Duchenne Muscular Dystrophy (DMD)… | Myopathies | À vérifier | Phase 1 | RECRUITING | The primary objective of this study is to evaluate the safety and tolerabi… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| synovial biopsy NCT07503821 · SYVIPRO — Synovial Tissue as a Biomarker in the Management of Pigmented Villonod… | Myopathies | Immunomodulation · Traitement symptomatique | Non applicable | RECRUITING | Pigmented villonodular synovitis (PVNS) is a rare joint disease caused by… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| zagociguat 15mg NCT06961344 · An Open-label Extension Safety Study of MELAS Patients Who Completed TIS6463-203… | Myopathies | À vérifier | Phase 2 | TERMINATED | PRIZM is a Phase 2b randomized, double-blind, placebo-controlled, 3-treatm… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| zeleciment basivarsen (DYNE-101) NCT07486934 · Efficacy, Safety, and Tolerability of Zeleciment Basivarsen (DYNE-101) in Partic… | Myopathies | À vérifier | Phase 3 | RECRUITING | The purpose of the study is to assess the efficacy, safety, and tolerabili… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| Deep Brain Stimulation Étude non communiquée | Épilepsie · Myopathies · Maladie de Parkinson | À vérifier | Non applicable | Actif | Background: \- Deep brain stimulation (DBS) is an approved surgery for cer… À vérifier | ClinicalTrials.gov 2026-11-06 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 644
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Real-world outcomes of BrECADD therapy in advanced-stage classical Ho… Cyclophosphamide · PMID 42448612 | Myopathies | Ralentissement de la progression · Thérapie génique | Publication | PubMed | Voir la publication source Advanced-stage classical Hodgkin lymphoma (cHL) has been traditionally treated with effective chemotherapy regimens, al… | British journal of haematology 2026-07-15 11:30:22 | Source |
| Evaluation of corticosteroid treatment in patients with post-traumati… dexamethasone · PMID 42448655 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Subacute post-traumatic ascending myelopathy (SPAM) is defined as a neurological deterioration extending several levels… | Spinal cord series and cases 2026-07-15 11:30:11 | Source |
| BAIBA attenuates pulmonary fibrosis by modulating the iron/ROS-mitoch… Metformin · PMID 42448057 | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Publication | PubMed | Voir la publication source Pulmonary fibrosis (PF) is a chronic and progressive lung disease with limited therapeutic options. Beta-aminoisobutyri… | Free radical biology & medicine 2026-07-15 11:30:08 | Source |
| High Volume Hemofiltration : what are the last indications in 2026 -… Metformin · PMID 42447139 | Myopathies | Neuroprotection | Publication | PubMed | Voir la publication source High-dose continuous therapies and especially High-volume hemofiltration has failed to demonstrate clinical benefit in… | Blood purification 2026-07-15 11:30:08 | Source |
| Effect of 37°C Pre-Warmed Versus Room Temperature Gadoxetic Acid Diso… GenPHSat injection (Safety) · PMID 42446484 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Compromised patient comfort and suboptimal arterial phase (AP) image quality remain unresolved challenges in Gd-EOB-DTP… | Journal of magnetic resonance imaging : JMRI 2026-07-14 21:30:42 | Source |
| Safety and Efficacy of TrenibotulinumtoxinE for Moderate-to-Severe Gl… GenPHSat injection (Safety) · PMID 42446897 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Glabellar lines (GLs) are facial furrows that can become aesthetically displeasing because of aging and repetitive musc… | Aesthetic surgery journal 2026-07-14 21:30:42 | Source |
| From Control to Elimination: Making the End of Dental Caries Thinkabl… Behavioral Interventions for Controlling Oral Behaviors · PMID 42446275 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Dental caries remains one of the most prevalent noncommunicable diseases worldwide despite decades of clinical and beha… | Community dentistry and oral epidemiology 2026-07-14 21:30:34 | Source |
| Impact of anti-TNF and anti-IL-12/IL-23 antibody therapy on periodont… Behavioral Interventions for Controlling Oral Behaviors · PMID 42445195 | Myopathies | Immunomodulation | Publication | PubMed | Voir la publication source Periodontitis prevalence is elevated in patients with inflammatory bowel diseases (IBD). Biological therapies targeting… | Frontiers in immunology 2026-07-14 21:30:34 | Source |
| [Real-world testing of digital health: the INSPIRE Living Lab : An in… test of walk · PMID 42446712 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Digitalization in healthcare offers great potential for improving the quality of care and efficiency but often fails du… | Orthopadie (Heidelberg, Germany) 2026-07-14 21:30:22 | Source |
| Efficacy and safety of mitoxantrone hydrochloride liposome/ thiotepa/… Fludarabine · PMID 42446104 | Myopathies | Ralentissement de la progression · Thérapie cellulaire | Publication | PubMed | Voir la publication source To investigate the efficacy and safety of MTBF as conditioning regimen for salvage allogeneic hematopoietic stem cell t… | Cell transplantation 2026-07-14 21:30:10 | Source |
| Application Timing-Dependent Impact of Donor Source on Outcomes After… Cyclophosphamide · PMID 42446167 | Myopathies | Thérapie cellulaire · Thérapie génique | Publication | PubMed | Voir la publication source Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is usually performed as a curative treatment for adult T… | Hematological oncology 2026-07-14 21:30:08 | Source |
| Salvage ultra-low-dose radiotherapy for conjunctival mantle cell lymp… Cyclophosphamide · PMID 42445702 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Mantle cell lymphoma (MCL) is an aggressive B-cell non-Hodgkin lymphoma with variable responses to frontline chemothera… | Reports of practical oncology and radiotherapy : journ… 2026-07-14 21:30:08 | Source |
| Evaluation of insulin, leptin, ghrelin, and adiponectin levels in typ… Metformin · PMID 42446258 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder, which is commonly related to reduced insulin responsiv… | Biomeditsinskaia khimiia 2026-07-14 21:29:33 | Source |
| Comparative Efficacy of Non-invasive Brain Stimulation for Pain, Anxi… Intermittent theta burst stimulation · PMID 42435147 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Although non-invasive brain stimulation (NIBS) has been used to manage chronic musculoskeletal pain (CMP) and related e… | Pain and therapy 2026-07-14 21:29:07 | Source |
| Functional near-infrared spectroscopy study of intermittent theta bur… Intermittent theta burst stimulation · PMID 42440696 | Myopathies | Ralentissement de la progression | Publication | PubMed | Voir la publication source Stroke is characterized by high morbidity and high disability rate, and is the main cause of long-term disability. To e… | Frontiers in human neuroscience 2026-07-14 21:29:07 | Source |
| An Unusual Genetic Variant of Long QT Syndrome with Late Presentation… Mexiletine · PMID 42405015 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source This case report describes a 57-year-old woman with a history of transient loss of consciousness, initially treated as… | The Journal of innovations in cardiac rhythm management 2026-07-14 16:28:50 | Source |
| Common genetic variants of the cardiac sodium channel alter patient r… Mexiletine · PMID 42422555 | Myopathies | Thérapie cellulaire | Publication | PubMed | Voir la publication source Several common variants have been identified in SCN5A, which encodes the cardiac sodium channel α-subunit Nav1.5 and is… | Journal of precision medicine (Amsterdam, Netherlands) 2026-07-14 16:28:50 | Source |
| Trunk-oriented Exercises Versus Whole-body Vibration on Abdominal Thi… Trunk Oriented Exercises Versus Whole-body Vibration for Duchenne Muscular Dystrophy · PMID 38… | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Progressive proximal muscle weakening in children with Duchenne muscular dystrophy (DMD) impairs postural adjustments b… | Journal of musculoskeletal & neuronal interactions 2026-07-14 16:28:20 | Source |
| "Nothing about us without us": Co-production of and 'How To' implemen… Pain Science Education · PMID 42345107 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Temporomandibular disorders (TMDs) affect up to 1 in 15 people, significantly impairing daily function and quality of l… | Primary dental journal 2026-07-14 16:28:18 | Source |
| Smallest Detectable Change of the Knowledge and Attitudes of Pain in… Pain Science Education · PMID 42333373 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Background Pain Science Education (PSE) aims to improve patients' understanding of pain based on modern pain science, e… | Cureus 2026-07-14 16:28:18 | Source |
Exploration — prudence
Pistes exploratoires 6
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| N-PPG N-PPG — modulation métabolique cérébrale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Myopat… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| Vecteur Ple389 (ADORA2A) MiniPromoter Ple389 — ciblage striatal | Myopathies | Thérapie génique | Hypothèse exploratoire | Rapprochement automatique non validé | Expression génique ciblée dans les neurones striataux Vecteur Ple389 (ADORA2A) est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être per… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| α-Amyrin α-Amyrin — protection mitochondriale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Protection mitochondriale et modulation de la pathologie Tau α-Amyrin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour Myopa… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Myopathies | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| Thonningianin A Thonningianin A — neuroprotection anti-amyloïde | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation du stress oxydatif et des protéines associées à Alzheimer Thonningianin A est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| Vutiglabridin Vutiglabridin — autophagie et PON2 | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Activation de PON2 et stimulation de l’autophagie Vutiglabridin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |