Vue transversale de la maladie
Myopathies
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
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1200 résultats correspondants
· 46 visibles sur cette page
dans le périmètre Myopathies
Niveau clinique
Études et traitements 550
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| Amlodipine NCT07075965 · CAP DM1 — Calcium Channel Blocker in Myotonic Dystrophy Type 1 | Myopathies | À vérifier | Phase 1 | NOT_YET_RECRUITING | The purpose of this study is to evaluate the effectiveness and mechanism o… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| Milnacipran NCT01747044 · Prospective Study of the Influence of the Diffuse Noxious Inhibitory Controls of… | Myopathies | Traitement symptomatique | Phase 2 | COMPLETED | Fibromyalgia affects 0.7 to 3.3% of the adult population and 7-10 times mo… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| Multimodal physiotherapy program NCT07577687 · Effect of Emg-Biofeedback and Multimodal Exercise on Temporomandibular Joint Dys… | Myopathies | Ralentissement de la progression · Traitement symptomatique | Non applicable | RECRUITING | Temporomandibular joint dysfunction (TMD) is a multifactorial musculoskele… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| Sodium hyaluronate with mannitol (Ostenil Tendon) NCT03984955 · CITTE — Comparing Injection Treatments for Tennis Elbow | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | Tennis elbow is one of the most common musculoskeletal problems affecting… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| Eteplirsen NCT06606340 · EVOLVE — A Long-term Observational Study Evaluating Eteplirsen, Golodirsen, or C… | Myopathies | À vérifier | À vérifier | ENROLLING_BY_INVITATION | This is a phase 4, multicenter, prospective, observational study designed… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:15 | Détail |
| KER-065 NCT07704099 · Safety and Efficacy of KER-065 in Participants With Duchenne Muscular Dystrophy | Myopathies | À vérifier | Phase 2 | RECRUITING | The purpose of this study is to evaluate the safety, tolerability, pharmac… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:15 | Détail |
| Tegacorat NCT07911995 · A Phase 2 Trial to Investigate the Efficacy, Safety, Tolerability, Pharmacokinet… | Myopathies | À vérifier | Phase 2 | NOT_YET_RECRUITING | This Phase 2 clinical trial will evaluate the efficacy, safety, tolerabili… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:15 | Détail |
| delandistrogene moxeparvovec NCT06241950 · A Gene Transfer Therapy Study to Evaluate the Safety and Efficacy of Delandistro… | Myopathies | À vérifier | Phase 1 | TERMINATED | This open-label, single-arm study will evaluate the safety and expression… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| Exopulse Mollii Suit NCT07459361 · Acute Effects of Wearable Electrical Stimulation in Stroke | Myopathies | Traitement symptomatique | Non applicable | COMPLETED | Cerebral Palsy (CP) is is estimated to be around 1.5-3 per live birth, wit… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| Instrument Assisted Soft Tissue Mobilization NCT07921784 · Effects of IASTM, Deep Friction Massage, and Sham Instrument-Assisted Soft Tissu… | Myopathies | Ralentissement de la progression · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Background: Non-specific low back pain is a leading cause of global disabi… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| ITB Titration Protocol NCT06606574 · PREDICT-ITB — Intrathecal Baclofen and Pediatric Dystonia | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | The goal of this study is to better understand outcomes in children with d… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| Nanopulsed Electromagnetic Field Therapy (SIS) NCT07550543 · PEMF Therapy in Shoulder Tendinopathy | Myopathies | Traitement symptomatique | Non applicable | COMPLETED | The goal of this clinical trial is to evaluate whether pulsed electromagne… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| nVNS Treatment NCT07288411 · Effects of Vagus Nerve Stimulation on Temporomandibular Disorders. | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | The study aims to examine the effects of transcutaneous non-invasive vagus… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| SPOT-03 NCT07188012 · Safety and Dystrophin Expression of SPOT-03 in Duchenne Muscular Dystrophy (DMD)… | Myopathies | À vérifier | Phase 1 | RECRUITING | The primary objective of this study is to evaluate the safety and tolerabi… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| synovial biopsy NCT07503821 · SYVIPRO — Synovial Tissue as a Biomarker in the Management of Pigmented Villonod… | Myopathies | Immunomodulation · Traitement symptomatique | Non applicable | RECRUITING | Pigmented villonodular synovitis (PVNS) is a rare joint disease caused by… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| zagociguat 15mg NCT06961344 · An Open-label Extension Safety Study of MELAS Patients Who Completed TIS6463-203… | Myopathies | À vérifier | Phase 2 | TERMINATED | PRIZM is a Phase 2b randomized, double-blind, placebo-controlled, 3-treatm… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| zeleciment basivarsen (DYNE-101) NCT07486934 · Efficacy, Safety, and Tolerability of Zeleciment Basivarsen (DYNE-101) in Partic… | Myopathies | À vérifier | Phase 3 | RECRUITING | The purpose of the study is to assess the efficacy, safety, and tolerabili… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| Deep Brain Stimulation Étude non communiquée | Épilepsie · Myopathies · Maladie de Parkinson | À vérifier | Non applicable | Actif | Background: \- Deep brain stimulation (DBS) is an approved surgery for cer… À vérifier | ClinicalTrials.gov 2026-11-06 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 644
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Hyaluronic acid nanoparticle as drug delivery carrier for the treatme… Diclofenac 1% Topical · PMID 42578876 | Myopathies | Immunomodulation | Publication | PubMed | Voir la publication source BackgroundAllergic conjunctivitis is an inflammatory disorder of the conjunctiva triggered by allergens. Although topic… | Bio-medical materials and engineering 2026-08-13 15:01:42 | Source |
| Successful Management of Refractory Cannabinoid Hyperemesis Syndrome… Capsaicin Topical Cream · PMID 42491286 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Cannabinoid hyperemesis syndrome (CHS) is a debilitating disorder of chronic, heavy cannabis users characterized by cyc… | Clinical medicine insights. Case reports 2026-08-13 15:01:41 | Source |
| Fat Embolism Syndrome Following Elective Orthopedic Surgery in a Pati… Chronic Corticosteroid Therapy · PMID 42572732 | Myopathies | Immunomodulation | Publication | PubMed | Voir la publication source Duchenne muscular dystrophy (DMD) is associated with substantial perioperative morbidity due to progressive cardiopulmo… | Cureus 2026-08-13 15:01:38 | Source |
| Recalibrating Therapeutic Priorities for Duchenne Muscular Dystrophy:… Ataluren · PMID 42510866 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Duchenne muscular dystrophy (DMD) has, for the first time, several mutation-specific drugs in clinical use. Four exon-s… | Genes 2026-08-13 15:01:37 | Source |
| Modular intramedullary knee arthrodesis for chronic periprosthetic jo… Limb salvage · PMID 42585983 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Chronic periprosthetic joint infection (PJI) after total knee arthroplasty (TKA) is a severe complication causing repea… | The Knee 2026-08-13 15:01:34 | Source |
| Primary Soft Tissue Sarcomas of the Extremities: A Nationwide Retrosp… Limb salvage · PMID 42588730 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source : The aim of this study was to determine the oncologic outcomes for adult patients with primary extremity soft tissue s… | Cancers 2026-08-13 15:01:34 | Source |
| Risk of glaucoma among patients using tadalafil for lower urinary tra… Tadalafil · PMID 42552102 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source To evaluate the association between tadalafil use for lower urinary tract symptoms (LUTS) and the risk of developing gl… | The British journal of ophthalmology 2026-08-13 15:01:34 | Source |
| Multidimensional Factors Influencing the Implementation of Early Mobi… The Impact of Early Mobilization Protocol in Patients in the ICU · PMID 42504084 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source This meta-synthesis of qualitative studies aimed to explore the experiences and perspectives of healthcare providers in… | Journal of advanced nursing 2026-08-13 15:01:28 | Source |
| Stepping it Up on Temporary Mechanical Circulatory Support - Mobiliza… The Impact of Early Mobilization Protocol in Patients in the ICU · PMID 42521141 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Early mobilization and prehabilitation in patients supported with temporary mechanical circulatory support (tMCS) have… | Journal of cardiac failure 2026-08-13 15:01:28 | Source |
| Clinical Impact of Complete Revascularization Before Left Ventricular… Revascularization · PMID 42590810 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Limited information exists regarding whether coronary revascularization by percutaneous coronary intervention (PCI) pri… | Artificial organs 2026-08-13 15:01:25 | Source |
| Postoperative perfusion volume on territorial arterial spin labeling… Revascularization · PMID 42591086 | Myopathies | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Cerebral hyperperfusion syndrome (CHS) after revascularization for moyamoya disease (MMD) represents a failure of cereb… | Frontiers in physiology 2026-08-13 15:01:25 | Source |
| Cohort, gender and spatial patterns of delayed school enrolment in th… COVID-19 Pandemic and Parents of Disabled Children · PMID 42527426 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Delayed school enrolment can be an important marker for developmental delays and be associated with adverse health even… | Scientific reports 2026-08-13 15:01:22 | Source |
| School Readiness, Learning Challenges, and Lifestyle Changes Among Ch… COVID-19 Pandemic and Parents of Disabled Children · PMID 42532839 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source The COVID-19 pandemic disrupted schooling worldwide. While there is evidence of declines in academic performance, the l… | The Journal of school health 2026-08-13 15:01:22 | Source |
| From trunk and hip muscle function to class allocation: understanding… Manual muscular test · PMID 42539762 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Functional assessment in wheelchair basketball (WB) has three evaluation stages: analysis of isolated functions, combin… | Frontiers in sports and active living 2026-08-13 15:01:21 | Source |
| Precision and Error Propagation in Static MEMS-IMU Inertial Navigatio… test of walk · PMID 42590462 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source This paper investigates the precision and stochastic error propagation of navigation solutions obtained from a low-cost… | Sensors (Basel, Switzerland) 2026-08-13 15:01:20 | Source |
| The Effect of Whole-Body Cryotherapy on Exercise Capacity of Healthy… test of walk · PMID 42590172 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source : To analyze the effect of whole-body cryotherapy on exercise tolerance in healthy, training men related to their profe… | Journal of clinical medicine 2026-08-13 15:01:20 | Source |
| A qualitative study on the vulnerability factors of unintentional inj… Awareness Levels of Caregivers of Disabled Children · PMID 42577259 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Unintentional injuries represent a primary cause of child mortality worldwide. However, child injury research in China… | Frontiers in public health 2026-08-13 15:01:19 | Source |
| Intrathecal Baclofen Pump Therapy for Medically Refractory Stiff Pers… baclofen · PMID 42578902 | Myopathies | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source This study aimed to describe clinical outcomes, dosing, and safety of intrathecal baclofen (ITB) therapy in patients wi… | Neuromodulation : journal of the International Neuromo… 2026-08-13 15:01:12 | Source |
| On-Demand Hospital Manufacturing of Baclofen Lozenges Using Pharmaceu… baclofen · PMID 42581260 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Dysphagia in neurological patients complicates oral drug administration. Manual preparation of lozenges/troches lacks p… | Pharmaceutical research 2026-08-13 15:01:12 | Source |
| Cytokine Release Syndrome Induced by Neoadjuvant Pembrolizumab in Ear… Prednisolone · PMID 42583655 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Cytokine release syndrome (CRS) is a rare but potentially severe immune-related adverse event associated with immune ch… | Case reports in oncology 2026-08-13 15:00:21 | Source |
Exploration — prudence
Pistes exploratoires 6
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| N-PPG N-PPG — modulation métabolique cérébrale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Myopat… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| Vecteur Ple389 (ADORA2A) MiniPromoter Ple389 — ciblage striatal | Myopathies | Thérapie génique | Hypothèse exploratoire | Rapprochement automatique non validé | Expression génique ciblée dans les neurones striataux Vecteur Ple389 (ADORA2A) est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être per… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| α-Amyrin α-Amyrin — protection mitochondriale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Protection mitochondriale et modulation de la pathologie Tau α-Amyrin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour Myopa… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Myopathies | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| Thonningianin A Thonningianin A — neuroprotection anti-amyloïde | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation du stress oxydatif et des protéines associées à Alzheimer Thonningianin A est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| Vutiglabridin Vutiglabridin — autophagie et PON2 | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Activation de PON2 et stimulation de l’autophagie Vutiglabridin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |