Vue transversale de la maladie
Myopathies
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
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1200 résultats correspondants
· 46 visibles sur cette page
dans le périmètre Myopathies
Niveau clinique
Études et traitements 550
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| Amlodipine NCT07075965 · CAP DM1 — Calcium Channel Blocker in Myotonic Dystrophy Type 1 | Myopathies | À vérifier | Phase 1 | NOT_YET_RECRUITING | The purpose of this study is to evaluate the effectiveness and mechanism o… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| Milnacipran NCT01747044 · Prospective Study of the Influence of the Diffuse Noxious Inhibitory Controls of… | Myopathies | Traitement symptomatique | Phase 2 | COMPLETED | Fibromyalgia affects 0.7 to 3.3% of the adult population and 7-10 times mo… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| Multimodal physiotherapy program NCT07577687 · Effect of Emg-Biofeedback and Multimodal Exercise on Temporomandibular Joint Dys… | Myopathies | Ralentissement de la progression · Traitement symptomatique | Non applicable | RECRUITING | Temporomandibular joint dysfunction (TMD) is a multifactorial musculoskele… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| Sodium hyaluronate with mannitol (Ostenil Tendon) NCT03984955 · CITTE — Comparing Injection Treatments for Tennis Elbow | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | Tennis elbow is one of the most common musculoskeletal problems affecting… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| Eteplirsen NCT06606340 · EVOLVE — A Long-term Observational Study Evaluating Eteplirsen, Golodirsen, or C… | Myopathies | À vérifier | À vérifier | ENROLLING_BY_INVITATION | This is a phase 4, multicenter, prospective, observational study designed… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:15 | Détail |
| KER-065 NCT07704099 · Safety and Efficacy of KER-065 in Participants With Duchenne Muscular Dystrophy | Myopathies | À vérifier | Phase 2 | RECRUITING | The purpose of this study is to evaluate the safety, tolerability, pharmac… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:15 | Détail |
| Tegacorat NCT07911995 · A Phase 2 Trial to Investigate the Efficacy, Safety, Tolerability, Pharmacokinet… | Myopathies | À vérifier | Phase 2 | NOT_YET_RECRUITING | This Phase 2 clinical trial will evaluate the efficacy, safety, tolerabili… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:15 | Détail |
| delandistrogene moxeparvovec NCT06241950 · A Gene Transfer Therapy Study to Evaluate the Safety and Efficacy of Delandistro… | Myopathies | À vérifier | Phase 1 | TERMINATED | This open-label, single-arm study will evaluate the safety and expression… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| Exopulse Mollii Suit NCT07459361 · Acute Effects of Wearable Electrical Stimulation in Stroke | Myopathies | Traitement symptomatique | Non applicable | COMPLETED | Cerebral Palsy (CP) is is estimated to be around 1.5-3 per live birth, wit… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| Instrument Assisted Soft Tissue Mobilization NCT07921784 · Effects of IASTM, Deep Friction Massage, and Sham Instrument-Assisted Soft Tissu… | Myopathies | Ralentissement de la progression · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Background: Non-specific low back pain is a leading cause of global disabi… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| ITB Titration Protocol NCT06606574 · PREDICT-ITB — Intrathecal Baclofen and Pediatric Dystonia | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | The goal of this study is to better understand outcomes in children with d… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| Nanopulsed Electromagnetic Field Therapy (SIS) NCT07550543 · PEMF Therapy in Shoulder Tendinopathy | Myopathies | Traitement symptomatique | Non applicable | COMPLETED | The goal of this clinical trial is to evaluate whether pulsed electromagne… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| nVNS Treatment NCT07288411 · Effects of Vagus Nerve Stimulation on Temporomandibular Disorders. | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | The study aims to examine the effects of transcutaneous non-invasive vagus… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| SPOT-03 NCT07188012 · Safety and Dystrophin Expression of SPOT-03 in Duchenne Muscular Dystrophy (DMD)… | Myopathies | À vérifier | Phase 1 | RECRUITING | The primary objective of this study is to evaluate the safety and tolerabi… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| synovial biopsy NCT07503821 · SYVIPRO — Synovial Tissue as a Biomarker in the Management of Pigmented Villonod… | Myopathies | Immunomodulation · Traitement symptomatique | Non applicable | RECRUITING | Pigmented villonodular synovitis (PVNS) is a rare joint disease caused by… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| zagociguat 15mg NCT06961344 · An Open-label Extension Safety Study of MELAS Patients Who Completed TIS6463-203… | Myopathies | À vérifier | Phase 2 | TERMINATED | PRIZM is a Phase 2b randomized, double-blind, placebo-controlled, 3-treatm… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| zeleciment basivarsen (DYNE-101) NCT07486934 · Efficacy, Safety, and Tolerability of Zeleciment Basivarsen (DYNE-101) in Partic… | Myopathies | À vérifier | Phase 3 | RECRUITING | The purpose of the study is to assess the efficacy, safety, and tolerabili… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:14 | Détail |
| Deep Brain Stimulation Étude non communiquée | Épilepsie · Myopathies · Maladie de Parkinson | À vérifier | Non applicable | Actif | Background: \- Deep brain stimulation (DBS) is an approved surgery for cer… À vérifier | ClinicalTrials.gov 2026-11-06 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 644
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Liver health in myotubular and centronuclear myopathies: a patient-dr… CMDPROS — Congenital Muscle Disease Study of Patient and Family Reported Medical Information ·… | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Liver health issues in X-linked myotubular myopathy and centronuclear myopathies have historically been under-recognize… | Neuromuscular disorders : NMD 2026-08-13 15:02:49 | Source |
| Six novel SACS mutations expand the autosomal recessive spastic ataxi… CMDPROS — Congenital Muscle Disease Study of Patient and Family Reported Medical Information ·… | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source BACKGROUND: The clinical spectrum of autosomal recessive spastic ataxia of Charlevoix–Saguenay (ARSACS) in Asian popula… | Orphanet journal of rare diseases 2026-08-13 15:02:49 | Source |
| Neuromorphic Devices and Computing for Sensing, Memory, and Control. Stem Cell · PMID 42591065 | Myopathies | Thérapie cellulaire | Publication | PubMed | Voir la publication source Neuromorphic devices are bioinspired electronic systems that mimic key structures and functions of the nervous system,… | Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026-08-13 15:02:48 | Source |
| Effect of Instrument-Assisted Soft Tissue Mobilization Combined With… Effect of Phonophoresis on Trigger Points · PMID 41206797 | Myopathies | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source The purpose of this study was to investigate the effects of instrument-assisted soft tissue mobilization (IASTM) and li… | Journal of manipulative and physiological therapeutics 2026-08-13 15:02:47 | Source |
| Platelet rich plasma therapy versus other modalities for treatment of… Effect of Phonophoresis on Trigger Points · PMID 38395675 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Plantar fasciitis (PF) is the most common cause of heel pain in adults. There are numerous non-operative treatments ava… | Foot and ankle surgery : official journal of the Europ… 2026-08-13 15:02:47 | Source |
| Clinical effect of kinesio taping combined with dry needling to myofa… Dry Needling for Myofascial Pain Syndrome · PMID 42545155 | Myopathies | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Shoulder-hand syndrome (SHS) is a common complication after stroke, characterized by pain, edema, and functional impair… | European journal of physical and rehabilitation medici… 2026-08-13 15:02:46 | Source |
| Comparative effects of low-level laser acupuncture and dry needling o… Dry Needling for Myofascial Pain Syndrome · PMID 42430011 | Myopathies | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source The purpose of this study was to compare the effectiveness of Low-Level Laser Acupuncture with Dry Needling along with… | Lasers in medical science 2026-08-13 15:02:46 | Source |
| Physical therapy interventions for awake and sleep bruxism: What has… Splint Therapy · PMID 42497348 | Myopathies | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source The objective of this systematic review was to summarize the physiotherapy (PT) treatments used over the last few decad… | Dental and medical problems 2026-08-13 15:02:45 | Source |
| Volume of Treatment of Temporomandibular Disorders in Adults-A Nation… Splint Therapy · PMID 42449475 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Temporomandibular disorders (TMD) present diverse signs and symptoms and often require clinical evaluation. To investig… | Journal of oral rehabilitation 2026-08-13 15:02:45 | Source |
| A Phase 1, Double-Blind, Placebo-Controlled Trial of Sevasemten (EDG-… Sevasemten Dose 2 · PMID 40452637 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Sevasemten (EDG-5506) is an orally administered, investigational small molecule that selectively modulates fast muscle… | Muscle & nerve 2026-08-13 15:02:43 | Source |
| Effects of sevasemten (EDG-5506) on safety, biomarkers, and functiona… Sevasemten Dose 1 · PMID 42308588 | Myopathies | Immunomodulation | Publication | PubMed | Voir la publication source Sevasemten (EDG-5506) is an orally administered, investigational small molecule that selectively modulates fast muscle… | EBioMedicine 2026-08-13 15:02:42 | Source |
| Human Disposition, Metabolism, and Excretion of Sevasemten (EDG-5506)… Sevasemten Dose 1 · PMID 42394192 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Sevasemten (EDG-5506) is a novel, orally bioavailable, investigational small molecule designed to selectively modulate… | Journal of clinical pharmacology 2026-08-13 15:02:42 | Source |
| Airway Clearance in Neuromuscular Disease. Lung Volume Recruitment (LVR) · PMID 39095145 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source High-quality respiratory care and airway clearance is essential for people with neuromuscular disease (pwNMD) as respir… | Sleep medicine clinics 2026-08-13 15:02:40 | Source |
| Effects of Thermal Aging and Subsequent Autoclave Treatment on the Ph… (-)-Epicatechin · PMID 42588794 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source This study evaluated the effects of aging and subsequent autoclave treatment on the proton nuclear magnetic resonance (… | Plants (Basel, Switzerland) 2026-08-13 15:02:40 | Source |
| Integrated Transcriptomic and Metabolomic Profiling Reveals the Invol… (-)-Epicatechin · PMID 42588842 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Sorghum seeds accumulate substantial amounts of condensed tannins (CTs), which are also referred to as proanthocyanidin… | Plants (Basel, Switzerland) 2026-08-13 15:02:40 | Source |
| Patterns of Adherence to Lung Volume Recruitment Therapy Amongst Indi… Lung Volume Recruitment (LVR) · PMID 41147267 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Duchenne muscular dystrophy (DMD) is associated with impaired airway clearance and chest wall restriction, treated with… | Pediatric pulmonology 2026-08-13 15:02:40 | Source |
| Cardiac Myosin Activators in Heart Failure: Experimental Advances Ami… danicamtiv · PMID 41858918 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Heart failure remains a leading cause of morbidity and mortality despite advances in neurohormonal and device-based the… | Drug design, development and therapy 2026-08-13 15:02:38 | Source |
| The role of cardiac myosin activators in dilated cardiomyopathy pharm… danicamtiv · PMID 42212862 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Expert opinion on pharmacotherapy 2026-08-13 15:02:38 | Source |
| Local anesthetics and antibiotics display synergistic and antagonisti… Mepivacaine Hydrochloride · PMID 39970538 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source To investigate the in vitro efficacy of antibiotics (amikacin, ceftiofur, and gentamicin) in combination with local ane… | American journal of veterinary research 2026-08-13 15:02:37 | Source |
| Solvent-Driven Enrichment and Multiplex Analysis of Local Anesthetics… Mepivacaine Hydrochloride · PMID 40286164 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Local anesthetics have been widely used in clinical analgesia due to their ability to provide effective regional pain m… | Molecules (Basel, Switzerland) 2026-08-13 15:02:37 | Source |
Exploration — prudence
Pistes exploratoires 6
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| N-PPG N-PPG — modulation métabolique cérébrale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Myopat… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| Vecteur Ple389 (ADORA2A) MiniPromoter Ple389 — ciblage striatal | Myopathies | Thérapie génique | Hypothèse exploratoire | Rapprochement automatique non validé | Expression génique ciblée dans les neurones striataux Vecteur Ple389 (ADORA2A) est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être per… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| α-Amyrin α-Amyrin — protection mitochondriale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Protection mitochondriale et modulation de la pathologie Tau α-Amyrin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour Myopa… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Myopathies | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| Thonningianin A Thonningianin A — neuroprotection anti-amyloïde | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation du stress oxydatif et des protéines associées à Alzheimer Thonningianin A est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| Vutiglabridin Vutiglabridin — autophagie et PON2 | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Activation de PON2 et stimulation de l’autophagie Vutiglabridin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |