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Toutes les maladies
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
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Chaque choix s’applique immédiatement aux quatre sections. Le filtre « type de SEP » n’apparaît que lorsque la sclérose en plaques est sélectionnée.
10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Mesenchymal stem cell-derived small extracellular vesicles in spinal… Allogeneic umbilical cord mesenchymal stem cells · PMID 42425423 | Sclérose en plaques | Remyélinisation · Remyélinisation indirecte / réparation · Neuroprotection · Ra… | Publication | PubMed | Voir la publication source Spinal cord injury (SCI) causes permanent neurological disability through a complex sequence of primary mechanical dama… | Journal of neuroscience methods 2026-08-16 13:04:01 | Source |
| The Potential Role of Mesenchymal Stem Cell Therapy for Moderate-to-S… Allogeneic umbilical cord mesenchymal stem cells · PMID 42596527 | Sclérose en plaques | Thérapie cellulaire · Thérapie génique | Publication | PubMed | Voir la publication source Despite currently available treatment options for moderate-to-severe atopic dermatitis (AD), some patients fail to achi… | Stem cells and development 2026-08-16 13:04:01 | Source |
| A more optimistic outlook about disease-modifying therapies and depre… Evaluation of Relapse Presence in Multiple Sclerosis · PMID 42217643 | Sclérose en plaques | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Disease-modifying therapies (DMTs) prevent relapses and slow disability progression in people with relapsing-remitting… | Journal of affective disorders 2026-08-16 13:04:00 | Source |
| Relating perivascular imaging measures to longitudinal lesion evoluti… Evaluation of Relapse Presence in Multiple Sclerosis · PMID 42320167 | Sclérose en plaques | Immunomodulation | Publication | PubMed | Voir la publication source Perivascular space (PVS) alterations may be associated with acute and chronic inflammatory activity in people with mult… | Multiple sclerosis and related disorders 2026-08-16 13:04:00 | Source |
| Telehealth tDCS to reduce cannabis use: A pilot RCT in multiple scler… Remotely Supervised Transcranial Direct Current Stimulation (RS - tDCS) · PMID 40378662 | Sclérose en plaques | Traitement symptomatique | Publication | PubMed | Voir la publication source Cannabis use is rising in the United States. Up to 30 % of individuals who use cannabis develop cannabis use disorder (… | Drug and alcohol dependence 2026-08-16 13:03:55 | Source |
| Effect of intraoperative 40-hz gamma-frequency auditory stimulation o… Active stimulation · PMID 41956975 | Sclérose en plaques | Neuroprotection · Traitement symptomatique | Publication | PubMed | Voir la publication source Postoperative delirium (POD) is a common and clinically significant complication among older adults undergoing major su… | Annals of medicine 2026-08-16 13:03:53 | Source |
| Effect of transcutaneous auricular vagus nerve stimulation (taVNS) on… Non-active stimulation · PMID 41794142 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source This study examined the effects of transcutaneous auricular vagus nerve stimulation (taVNS) on inhibitory control durin… | Behavioural brain research 2026-08-16 13:03:53 | Source |
| Benefits of 12-week self-paced training combined with melatonin suppl… RehaMS — Exercise Therapy in Multiple Sclerosis · PMID 42217742 | Sclérose en plaques | Neuroprotection · Immunomodulation | Publication | PubMed | Voir la publication source Concurrent aerobic-resistance training has been reported to be beneficial for oxidative stress, inflammation, hyperlipi… | Brain research bulletin 2026-08-16 13:03:49 | Source |
| Educational programs based on healthy habits to improve quality of li… RehaMS — Exercise Therapy in Multiple Sclerosis · PMID 42462809 | Sclérose en plaques | Traitement symptomatique | Publication | PubMed | Voir la publication source Multiple sclerosis (MS) is a chronic neurological disease primarily affecting young women. Fatigue, one of its most dis… | Contemporary clinical trials 2026-08-16 13:03:49 | Source |
| Gastric Metastasis of Uterine Leiomyosarcoma Detected During Surveill… Control · PMID 42416860 | Accident vasculaire cérébral · Épilepsie · Maladie de Parkinson · Scl… | Traitement symptomatique | Publication | PubMed | Voir la publication source Uterine leiomyosarcoma (uLMS) is a rare, aggressive uterine malignancy that usually metastasizes hematogenously, wherea… | DEN open 2026-08-16 13:03:48 | Source |
| Minimal supply chain and forecasting testing volumes for clinical bac… Control · PMID 42542126 | Accident vasculaire cérébral · Épilepsie · Maladie de Parkinson · Scl… | À vérifier | Publication | PubMed | Voir la publication source Inadequate access to clinical bacteriology testing in low-resource settings compromises individual patient care and con… | The Lancet. Microbe 2026-08-16 13:03:48 | Source |
| Monocyte Oxidative Stress Underlies Persistent Immune Activation in L… tVNS · PMID 42245008 | Accident vasculaire cérébral · Sclérose en plaques | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Long COVID Postural Orthostatic Tachycardia Syndrome (LCPOTS) is characterized by persistent orthostatic tachycardia an… | medRxiv : the preprint server for health sciences 2026-08-16 13:03:48 | Source |
| Transcutaneous vagus nerve stimulation enhances reward-effort efficie… tVNS · PMID 42385861 | Accident vasculaire cérébral · Sclérose en plaques | Traitement symptomatique | Publication | PubMed | Voir la publication source Major depressive disorder (MDD) is a highly prevalent psychiatric disorder with changes in motivation to work for rewar… | Journal of affective disorders 2026-08-16 13:03:48 | Source |
| Update on Sedation for Upper Gastrointestinal Endoscopy in Japan: Cur… Control · PMID 42597464 | Accident vasculaire cérébral · Épilepsie · Maladie de Parkinson · Scl… | À vérifier | Publication | PubMed | Voir la publication source Sedation is an essential component of upper gastrointestinal endoscopy because it reduces patient discomfort and anxiet… | DEN open 2026-08-16 13:03:48 | Source |
| Bio-Inspired lipid nanovesicles (iNVs) incorporating membrane protein… tSCS · PMID 41604518 | Accident vasculaire cérébral · Sclérose en plaques · Sclérose en plaq… | Thérapie cellulaire · Thérapie génique | Publication | PubMed | Voir la publication source The potential of human tendon-stem-cell-inspired nanovesicles (hTSC-iNVs) to act as a delivery platform for Tenomodulin… | Artificial cells, nanomedicine, and biotechnology 2026-08-16 13:03:47 | Source |
| Combined activity-based therapy and transcutaneous spinal cord stimul… tSCS · PMID 42601092 | Accident vasculaire cérébral · Sclérose en plaques · Sclérose en plaq… | Thérapie génique | Publication | PubMed | Voir la publication source Activity-based therapy (ABT) delivers intensive, repetitive sensorimotor stimulation to enhance neuroplasticity after s… | BMJ open 2026-08-16 13:03:47 | Source |
| The imprinted Peg3 gene is a potent regulator of the DNA methylome in… tSCS · PMID 42492511 | Accident vasculaire cérébral · Sclérose en plaques · Sclérose en plaq… | Immunomodulation · Thérapie cellulaire · Thérapie génique | Publication | PubMed | Voir la publication source Paternally expressed gene 3 (Peg3) is an imprinted gene whose knockout (KO) causes placental and fetal growth deficits… | Stem cell reports 2026-08-16 13:03:47 | Source |
| Optimizing estradiol serum levels for optimal skeletal and cardiovasc… estradiol · PMID 42417704 | Sclérose en plaques | Traitement symptomatique | Publication | PubMed | Voir la publication source Identify estradiol serum levels associated with vasomotor symptom relief and assess their effects on osteoporosis and c… | Gynecological endocrinology : the official journal of… 2026-08-16 13:03:28 | Source |
| Restoring ovulation in functional hypothalamic amenorrhea: impact of… estradiol · PMID 42176250 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source Up to 50% of women with functional hypothalamic amenorrhea (FHA) exhibit polycystic ovarian morphology (PCOM) on ultras… | Gynecological endocrinology : the official journal of… 2026-08-16 13:03:28 | Source |
| Transdermal versus oral hormone replacement therapy and bone mass den… estradiol · PMID 42351362 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source Women with Turner syndrome (TS) are at increased risk of reduced bone mineral density (BMD) due to primary ovarian insu… | Gynecological endocrinology : the official journal of… 2026-08-16 13:03:28 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||