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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Anifrolumab NCT07751848 · LOTUS — A Study of Outcomes in Chinese Patients Treated With Anifrolumab Who Hav… | Lupus | À vérifier | Phase 3 | RECRUITING | This is an observational study, in which the main research question is to… À vérifier | ClinicalTrials.gov 2026-09-27 04:37:02 | Détail |
| Anifrolumab + APFS NCT07630714 · A Study to Investigate Pharmacokinetics, Pharmacodynamics, and Safety of Subcuta… | Lupus | À vérifier | Phase 2 | RECRUITING | The purpose of this study is to characterize the pharmacokinetics (PK), ph… À vérifier | ClinicalTrials.gov 2026-09-27 04:37:02 | Détail |
| BCT301 NCT07301164 · Clinical Study of BCT301 Cell Injection Therapy for Refractory Autoimmune Diseas… | Lupus | Immunomodulation · Thérapie cellulaire | Phase 1 | RECRUITING | This study primarily involves the use of BCT301, an anti-CD19 Chemically i… À vérifier | ClinicalTrials.gov 2026-09-27 04:37:02 | Détail |
| Biospecimen Collection NCT03816345 · Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Pa… | Lupus | À vérifier | Phase 1 | RECRUITING | This phase III trial compares standard of care hormone therapy plus riboci… À vérifier | ClinicalTrials.gov 2026-09-27 04:37:02 | Détail |
| CART19 NCT06839976 · CD19-Directed Chimeric Antigen Receptor Autologous T Cells (CART19) for Lupus | Lupus | Immunomodulation | Phase 1/2 | RECRUITING | This is a single-center, single-arm, open-label phase 1/2 study of CART19… À vérifier | ClinicalTrials.gov 2026-09-27 04:37:02 | Détail |
| F182112 NCT07829614 · F182112 Phase Ib Clinical Study for the Treatment of Patients With Systemic Lupu… | Lupus | Immunomodulation | Phase 1 | RECRUITING | The investigational drug is an injectable recombinant humanized anti-BCMA/… À vérifier | ClinicalTrials.gov 2026-09-27 04:37:02 | Détail |
| Enpatoran NCT07840287 · A Long-Term Extension (LTE) Study Of Enpatoran In Cutaneous Manifestations Of Lu… | Lupus | À vérifier | Phase 3 | NOT_YET_RECRUITING | The purpose of this global, multicenter, Phase 3 study is to evaluate the… À vérifier | ClinicalTrials.gov 2026-09-27 04:37:01 | Détail |
| 5% 5-fluorouracil Topical Cream NCT07545746 · ASCEND — Adjuvant 5-Fluorouracil Following Thermal Ablation to Improve HPV Treat… | Cancer | À vérifier | Phase 2 | NOT_YET_RECRUITING | This randomized, placebo-controlled trial will evaluate self-administered… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:57 | Détail |
| Biopsy NCT03238664 · Robot-Assisted Laparoscopic High-Intensity Focused Ultrasound and Radical Cystec… | Cancer | Traitement symptomatique | Non applicable | WITHDRAWN | Background: EP0057 (formerly CRLX101) consists of a sugar molecule cyclode… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:57 | Détail |
| EPIONE® CT-Guided Percutaneous procedures NCT05529979 · SaFE — Epione® Post-Market Clinical Follow-up Study | Cancer | À vérifier | À vérifier | COMPLETED | Post-Market Clinical Follow-up study in order to consolidate performance a… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:57 | Détail |
| Irreversible Electroporation NCT02828709 · Safety and Feasibility of IRE for SRMs | Cancer | Traitement symptomatique · Thérapie génique | Phase 2 | UNKNOWN | Up to 16 patients with confirmed low- or intermediate risk prostate cancer… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:57 | Détail |
| Low-temperature Plasma Surgery System NCT03204084 · Assessment of Low-temperature Plasma Surgery System in Pterygium With Fibrin Glu… | Cancer | Immunomodulation | À vérifier | COMPLETED | Pterygium is a wing-shaped fibrovascular tissue that has proliferated onto… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:57 | Détail |
| Pre-treatment tumour oxygen measurements NCT00160979 · Transrectal Tumour Oxygen - US Army | Cancer | À vérifier | Phase 2 | COMPLETED | Prostate cancer is now the most commonly diagnosed tumor among men in the… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:57 | Détail |
| Radiofrequency Ablation NCT05580224 · Anatomical Radiofrequency Ablation for Small Hepatocellular Carcinoma | Cancer | À vérifier | Non applicable | UNKNOWN | The objective of this study is to compile real-world outcomes of Boston Sc… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:57 | Détail |
| Stereotactic Body Radiation Therapy (SBRT) NCT02782715 · Microwave Ablation With MRI-Guided SBRT Boost in Renal Cell Carcinoma | Cancer | Traitement symptomatique · Thérapie génique | Phase 1/2 | TERMINATED | Prostate cancer is a common cancer, and a significant cause of cancer deat… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:57 | Détail |
| Thermal ablation NCT03088150 · COLLISION Trial - Colorectal Liver Metastases: Surgery vs Thermal Ablation | Cancer | À vérifier | Non applicable | UNKNOWN | The primary objective is to prove non-inferiority of thermal ablation comp… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:57 | Détail |
| ExAblate 2100 NCT00981578 · ExAblate Conformal Bone System Treatment of Metastatic Bone Tumors for the Palli… | Cancer | Traitement symptomatique | Non applicable | TERMINATED | A study to evaluate the safety and initial effectiveness of the ExAblate 2… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:56 | Détail |
| ACE-232 tablets NCT06801236 · Phase 1 Study of ACE-232 to Treat Patients With Metastatic Castration-Resistant… | Cancer | À vérifier | Phase 1 | RECRUITING | This is an open label, phase I, multi-center study aiming to assess the sa… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:55 | Détail |
| MK-1045 NCT07519772 · WaveSpan-008 — A Clinical Study of MK-1045 in People With Non-Hodgkin Lymphoma (… | Cancer | Thérapie génique | Phase 1/2 | RECRUITING | This study looks at a study medicine called MK-1045 in people with lupus a… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:55 | Détail |
| Pasritamig NCT07164443 · KLK2-comPAS — A Study of Pasritamig With or Without JNJ-87189401 Versus Placebo… | Cancer | À vérifier | Phase 3 | RECRUITING | The purpose of this study is to evaluate the overall survival (length of t… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:55 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effects of continuous vs. intermittent transcutaneous electrical stim… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 41866984 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source To compare the effects of two transcutaneous electrical stimulation (TES) patterns applied to the auricular branches of… | Cranio : the journal of craniomandibular practice 2026-11-08 04:38:07 | Source |
| Optimizing Percutaneous Tibial Nerve Stimulation Intensity for Overac… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42554545 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source Overactive bladder (OAB) is a significant global health issue. The standard percutaneous tibial nerve stimulation (PTNS… | Neuromodulation : journal of the International Neuromo… 2026-11-08 04:38:07 | Source |
| Transcutaneous auricular vagus nerve stimulation improves dysautonomi… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42802247 | Maladie rénale chronique | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Autonomic nervous system dysfunction is highly prevalent in hypermobile Ehlers-Danlos syndrome (hEDS) and contributes s… | Neurological sciences : official journal of the Italia… 2026-11-08 04:38:07 | Source |
| Factors associated with high-flow therapy failure in COVID-19-related… Non-Invasive Positive Pressure Ventilation · PMID 42888091 | Maladie rénale chronique | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source The optimal selection of non-invasive respiratory support for patients with COVID-19-related acute hypoxemic respirator… | Enfermedades infecciosas y microbiologia clinica (Engl… 2026-11-08 04:38:06 | Source |
| High-Flow Nasal Cannula in Adult Acute Care: Physiological Mechanisms… Non-Invasive Positive Pressure Ventilation · PMID 42942512 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source High-flow nasal cannula (HFNC) oxygen therapy is widely used in emergency, intensive care, perioperative, and procedura… | Medicina (Kaunas, Lithuania) 2026-11-08 04:38:06 | Source |
| Impact of respiratory support on time to achieve full oral feeding in… Non-Invasive Positive Pressure Ventilation · PMID 42871336 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source Very low birth weight infants often require respiratory support, which may delay full oral feeding. The independent rol… | Frontiers in pediatrics 2026-11-08 04:38:06 | Source |
| A comparative analysis of 3MAX aspiration versus 3 mm Trevo Retriever… Thromboaspiration catheter · PMID 31243066 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Although aspiration and stent retriever thrombectomy perform similarly in proximal occlusions, no comparative series ar… | Journal of neurointerventional surgery 2026-11-08 04:38:02 | Source |
| Percutaneous Pulmonary Thrombectomy Beyond Acute Pulmonary Embolism:… Thromboaspiration catheter · PMID 38385241 | Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Subacute massive pulmonary embolism is an uncommon manifestation of severe pulmonary embolism associated with poor prog… | Journal of endovascular therapy : an official journal… 2026-11-08 04:38:02 | Source |
| Simplified classification of cavernous internal carotid artery tortuo… Thromboaspiration catheter · PMID 35475775 | Hypertension artérielle · Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Thromboaspiration catheters are increasingly used for the endovascular treatment of large vessel stroke (LVS), while to… | Neurological research 2026-11-08 04:38:02 | Source |
| Multifocal continuous theta burst stimulation in idiopathic generaliz… Continuous Theta Burst Stimulation (cTBS) · PMID 42731195 | Accident vasculaire cérébral | Traitement symptomatique | Publication | PubMed | Voir la publication source Idiopathic generalized epilepsy (IGE) is a disorder of the cortico-subcortical networks. Continuous theta burst stimula… | Clinical neurophysiology : official journal of the Int… 2026-11-08 04:38:00 | Source |
| Optimizing brain functional-structural architecture with cTBS to redu… Continuous Theta Burst Stimulation (cTBS) · PMID 42457860 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Alcohol use disorder (AUD) is characterized by high relapse rates, necessitating novel interventions. Continuous theta-… | Molecular psychiatry 2026-11-08 04:38:00 | Source |
| Digital Outreach to Improve Statin Refills in Patients With Low Stati… Cordio System · PMID 42667613 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Statin nonadherence is a leading, addressable driver of preventable cardiovascular events. Although health systems rout… | JAMA 2026-11-08 04:37:54 | Source |
| Endovascular ablation of the right greater splanchnic nerve for the m… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42257781 | Insuffisance cardiaque | Traitement symptomatique | Publication | PubMed | Voir la publication source Heart failure with preserved ejection fraction (HFpEF) remains difficult to manage because conventional therapies often… | The Egyptian heart journal : (EHJ) : official bulletin… 2026-11-08 04:37:54 | Source |
| Incidence, medical therapy, and outcomes in heart failure with improv… Cordio System · PMID 42702264 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source To assess the incidence of heart failure with improved ejection fraction (HFimpEF) across guideline definitions (ACC/AH… | American heart journal 2026-11-08 04:37:54 | Source |
| Relationship Between the Azygos Vein and the Greater Splanchnic Nerve… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42249803 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Although ablation of the greater splanchnic nerve is now being used to treat some patients with heart failure, the anat… | Clinical anatomy (New York, N.Y.) 2026-11-08 04:37:54 | Source |
| Validation of the PREVENT-HF Risk Prediction Equation in US Veterans. Cordio System · PMID 42969140 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Circulation 2026-11-08 04:37:54 | Source |
| Changes in right ventricular-pulmonary artery coupling after transcat… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42822601 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Right ventricular-pulmonary artery (RV-PA) coupling is an established marker of prognosis in mitral regurgitation (MR),… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Intraprocedural evaluation of residual mitral and tricuspid regurgita… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42982241 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Transcatheter edge-to-edge repair (TEER) has emerged as an established therapeutic option for selected patients with se… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Tricuspid transcatheter edge-to-edge repair versus transcatheter tric… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42989943 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Recent clinical studies of tricuspid transcatheter edge-to-edge repair (T-TEER) and transcatheter tricuspid valve repla… | Current opinion in cardiology 2026-11-08 04:37:47 | Source |
| Automated Production of Gene-Edited CAR-T Cells for People Living wit… RAPA-501 Autologous T stem cells · PMID 42847201 | Cancer | Thérapie cellulaire · Thérapie génique | Publication | PubMed | Voir la publication source Adoptive transfer of gene-modified autologous T cells, for example, expressing chimeric antigen receptors (CARs), is a… | Human gene therapy 2026-11-08 04:37:39 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||