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Périmètre

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Chaque choix s’applique immédiatement aux quatre sections. Le filtre « type de SEP » n’apparaît que lorsque la sclérose en plaques est sélectionnée.

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Essais et traitements5743Données cliniques et programmes
Recherches et trouvailles21Pipeline scientifique
Publications4871Références reliées aux maladies
Pistes exploratoires0Hypothèses non validées
10635 résultats correspondants · 41 visibles sur cette page dans le périmètre Toutes les maladies
Niveau clinique

Études et traitements 5743

Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.

Molécule / élément Maladie / population Objectif Phase / stade Statut / preuve Mécanisme / résumé Source Détail
Pulsed Field (PF) /Radiofrequency (RF) Catheter ablation NCT06272981 · PulseSmart — A Study of the THERMOCOOL SMARTTOUCH Surround Flow (SF) Catheter Wi… Maladie coronarienne Traitement symptomatique Non applicable COMPLETED The purpose of this study is to demonstrate safety and effectiveness of th… À vérifier ClinicalTrials.gov 2026-10-18 04:37:23 Détail
Saline NCT01000350 · Intravenous (IV) Saline and Exercise in Postural Tachycardia Syndrome (POTS) Maladie coronarienne À vérifier Non applicable ACTIVE_NOT_RECRUITING The purpose of this study is to evaluate whether the use of ACTH in additi… À vérifier ClinicalTrials.gov 2026-10-18 04:37:23 Détail
Sevoflurane NCT07877116 · Sevoflurane Versus Propofol Anesthesia in Intracardiac Echocardiography-Guided A… Maladie coronarienne À vérifier Phase 4 NOT_YET_RECRUITING This prospective, randomized, single-center study will compare sevoflurane… À vérifier ClinicalTrials.gov 2026-10-18 04:37:23 Détail
BrainProtect System NCT07872982 · BrainProtect-guided, Real-time Cerebral Autoregulation Monitoring and Protection… Maladie coronarienne À vérifier Non applicable NOT_YET_RECRUITING The purpose of this clinical investigation is to evaluate the clinical per… À vérifier ClinicalTrials.gov 2026-10-18 04:37:22 Détail
Dapagliflozin 10mg Tab NCT06009874 · Clinical Investigation of the Cardioprotective Effect of Early Administration of… Maladie coronarienne À vérifier Non applicable RECRUITING This study aims to investigate the effect of early administration of DAPA… À vérifier ClinicalTrials.gov 2026-10-18 04:37:22 Détail
flecainide NCT07405671 · ReCAST AF — Flecainide Safety in Patients With Coronary Artery Disease and Atria… Maladie coronarienne Traitement symptomatique · Thérapie génique Phase 4 RECRUITING The goal of this clinical trial is to learn whether the antiarrhythmic dru… À vérifier ClinicalTrials.gov 2026-10-18 04:37:22 Détail
jailed wire technique NCT07873879 · Modified Jailed Balloon Technique vs Jailed Wire Technique in Coronary Bifurcati… Maladie coronarienne À vérifier Non applicable NOT_YET_RECRUITING Randomized clinical trial between jailed wire technique and modified jaile… À vérifier ClinicalTrials.gov 2026-10-18 04:37:22 Détail
NSR IDE-MRI: Research pulse sequences NCT01143454 · Characterization of Patients With Uncommon Presentations and/or Uncommon Disease… Maladie coronarienne Immunomodulation À vérifier RECRUITING Background: \- Researchers are interested in studying individuals who have… À vérifier ClinicalTrials.gov 2026-10-18 04:37:22 Détail
Pelacarsen NCT07625306 · Lp(a) Lowering Study of Pelacarsen (TQJ230) in Patients in the US With Elevated… Maladie coronarienne À vérifier Phase 3 WITHDRAWN CTQJ230A1US13 is a randomized, double-blind, placebo-controlled, multicent… À vérifier ClinicalTrials.gov 2026-10-18 04:37:22 Détail
1-Month DAPT NCT07879430 · ADAPT-DCB — 1-Month Versus 6-Month Dual Antiplatelet Therapy After Successful Dr… Maladie coronarienne À vérifier Non applicable NOT_YET_RECRUITING This study will compare the clinical outcomes of a 1-month dual antiplatel… À vérifier ClinicalTrials.gov 2026-10-18 04:37:21 Détail
Acetylsalicylic acid ASA NCT07683923 · Spontaneous Coronary Artery Dissection - AntipLatelet Therapy Intensity in Guide… Maladie coronarienne Traitement symptomatique · Thérapie génique Phase 4 NOT_YET_RECRUITING Spontaneous coronary artery dissection (SCAD) is a rare cause of acute cor… À vérifier ClinicalTrials.gov 2026-10-18 04:37:21 Détail
AMJ-401 NCT07373353 · A Clinical Evaluation of AMJ-401 Maladie coronarienne À vérifier Non applicable ACTIVE_NOT_RECRUITING A Clinical Evaluation of AMJ-401 in the Treatment of Subjects with Ischemi… À vérifier ClinicalTrials.gov 2026-10-18 04:37:21 Détail
balloon angioplasty NCT07855003 · Evaluate the Clinical Efficacy and Safety of Non-Compliant PTCA Balloon Dilatati… Maladie coronarienne À vérifier À vérifier COMPLETED This multi-center, retrospective study included patients diagnosed with co… À vérifier ClinicalTrials.gov 2026-10-18 04:37:21 Détail
Clopidogrel NCT07876336 · Prevalence of CYP2C19 Genetic Polymorphisms Among Egyptian Patients Receiving Cl… Maladie coronarienne Traitement symptomatique À vérifier ENROLLING_BY_INVITATION This trial aims to compare the safety and efficacy of apixaban alone versu… À vérifier ClinicalTrials.gov 2026-10-18 04:37:21 Détail
Conventional Chest Physiotherapy NCT07875049 · Additional Effects of Flutter With Conventional Chest Physiotherapy on Peak Expi… Maladie coronarienne À vérifier Non applicable RECRUITING Flutter therapy is an oscillating positive expiratory pressure (OPEP) tech… À vérifier ClinicalTrials.gov 2026-10-18 04:37:21 Détail
Coronary CTA NCT07460583 · ProActive Athlete Heart Program: Proposal for Cardiac Risk Screening in Former H… Maladie coronarienne À vérifier Non applicable NOT_YET_RECRUITING AI-Guided Coronary CT Angiography Screening in Former High-Intensity Athle… À vérifier ClinicalTrials.gov 2026-10-18 04:37:21 Détail
Coronary Drug-Coated Balloon NCT07875088 · RW-DCB — Real-World Outcomes of Drug-Coated Balloon Angioplasty in Coronary Arte… Maladie coronarienne À vérifier À vérifier NOT_YET_RECRUITING The Real-World Drug-Coated Balloon Registry (RW-DCB) is an investigator-in… À vérifier ClinicalTrials.gov 2026-10-18 04:37:21 Détail
IVUS-Guided Sirolimus-Coated Balloon NCT07796412 · IVUS-SCB — IVUS-Guided Sirolimus-Coated Balloon Versus Sirolimus-Eluting Stent f… Maladie coronarienne À vérifier Non applicable NOT_YET_RECRUITING The goal of this interventional study is to evaluate the efficacy and safe… À vérifier ClinicalTrials.gov 2026-10-18 04:37:21 Détail
Minimally Invasive Extracorporeal Circulation NCT07823400 · MIECC-CABG — MIECC vs Conventional Cardiopulmonary Bypass and Systemic Inflammat… Maladie coronarienne Immunomodulation À vérifier ACTIVE_NOT_RECRUITING This prospective observational study evaluates the effects of minimally in… À vérifier ClinicalTrials.gov 2026-10-18 04:37:21 Détail
Norepinephrine NCT07562932 · ACTION-CS — Assessing Catecholamine Treatment Initiation Options: Norepinephrine… Maladie coronarienne Ralentissement de la progression · Thérapie génique Non applicable RECRUITING The goal of this multicenter, open-label, randomized clinical trial is to… À vérifier ClinicalTrials.gov 2026-10-18 04:37:21 Détail
Découverte scientifique

Recherches et trouvailles 21

Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.

Molécule / élément Maladie / population Objectif Phase / stade Statut / preuve Mécanisme / résumé Source Détail
4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation Sclérose latérale amyotrophique Neuroprotection · Immunomodulation Découverte fondamentale Exploratoire Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… Revue scientifique 2024-07-01 Détail
Bibliographie

Publications 4871

Références bibliographiques de la base locale et accès à leur source originale.

Molécule / élément Maladie / population Objectif Phase / stade Statut / preuve Mécanisme / résumé Source Détail
Effects of continuous vs. intermittent transcutaneous electrical stim… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 41866984 Maladie rénale chronique Traitement symptomatique Publication PubMed Voir la publication source To compare the effects of two transcutaneous electrical stimulation (TES) patterns applied to the auricular branches of… Cranio : the journal of craniomandibular practice 2026-11-08 04:38:07 Source
Optimizing Percutaneous Tibial Nerve Stimulation Intensity for Overac… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42554545 Maladie rénale chronique Traitement symptomatique Publication PubMed Voir la publication source Overactive bladder (OAB) is a significant global health issue. The standard percutaneous tibial nerve stimulation (PTNS… Neuromodulation : journal of the International Neuromo… 2026-11-08 04:38:07 Source
Transcutaneous auricular vagus nerve stimulation improves dysautonomi… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42802247 Maladie rénale chronique Immunomodulation · Traitement symptomatique Publication PubMed Voir la publication source Autonomic nervous system dysfunction is highly prevalent in hypermobile Ehlers-Danlos syndrome (hEDS) and contributes s… Neurological sciences : official journal of the Italia… 2026-11-08 04:38:07 Source
Factors associated with high-flow therapy failure in COVID-19-related… Non-Invasive Positive Pressure Ventilation · PMID 42888091 Maladie rénale chronique Traitement symptomatique · Thérapie génique Publication PubMed Voir la publication source The optimal selection of non-invasive respiratory support for patients with COVID-19-related acute hypoxemic respirator… Enfermedades infecciosas y microbiologia clinica (Engl… 2026-11-08 04:38:06 Source
High-Flow Nasal Cannula in Adult Acute Care: Physiological Mechanisms… Non-Invasive Positive Pressure Ventilation · PMID 42942512 Maladie rénale chronique À vérifier Publication PubMed Voir la publication source High-flow nasal cannula (HFNC) oxygen therapy is widely used in emergency, intensive care, perioperative, and procedura… Medicina (Kaunas, Lithuania) 2026-11-08 04:38:06 Source
Impact of respiratory support on time to achieve full oral feeding in… Non-Invasive Positive Pressure Ventilation · PMID 42871336 Maladie rénale chronique À vérifier Publication PubMed Voir la publication source Very low birth weight infants often require respiratory support, which may delay full oral feeding. The independent rol… Frontiers in pediatrics 2026-11-08 04:38:06 Source
A comparative analysis of 3MAX aspiration versus 3 mm Trevo Retriever… Thromboaspiration catheter · PMID 31243066 Accident vasculaire cérébral À vérifier Publication PubMed Voir la publication source Although aspiration and stent retriever thrombectomy perform similarly in proximal occlusions, no comparative series ar… Journal of neurointerventional surgery 2026-11-08 04:38:02 Source
Percutaneous Pulmonary Thrombectomy Beyond Acute Pulmonary Embolism:… Thromboaspiration catheter · PMID 38385241 Accident vasculaire cérébral Thérapie génique Publication PubMed Voir la publication source Subacute massive pulmonary embolism is an uncommon manifestation of severe pulmonary embolism associated with poor prog… Journal of endovascular therapy : an official journal… 2026-11-08 04:38:02 Source
Simplified classification of cavernous internal carotid artery tortuo… Thromboaspiration catheter · PMID 35475775 Hypertension artérielle · Accident vasculaire cérébral Thérapie génique Publication PubMed Voir la publication source Thromboaspiration catheters are increasingly used for the endovascular treatment of large vessel stroke (LVS), while to… Neurological research 2026-11-08 04:38:02 Source
Multifocal continuous theta burst stimulation in idiopathic generaliz… Continuous Theta Burst Stimulation (cTBS) · PMID 42731195 Accident vasculaire cérébral Traitement symptomatique Publication PubMed Voir la publication source Idiopathic generalized epilepsy (IGE) is a disorder of the cortico-subcortical networks. Continuous theta burst stimula… Clinical neurophysiology : official journal of the Int… 2026-11-08 04:38:00 Source
Optimizing brain functional-structural architecture with cTBS to redu… Continuous Theta Burst Stimulation (cTBS) · PMID 42457860 Accident vasculaire cérébral À vérifier Publication PubMed Voir la publication source Alcohol use disorder (AUD) is characterized by high relapse rates, necessitating novel interventions. Continuous theta-… Molecular psychiatry 2026-11-08 04:38:00 Source
Digital Outreach to Improve Statin Refills in Patients With Low Stati… Cordio System · PMID 42667613 Insuffisance cardiaque À vérifier Publication PubMed Voir la publication source Statin nonadherence is a leading, addressable driver of preventable cardiovascular events. Although health systems rout… JAMA 2026-11-08 04:37:54 Source
Endovascular ablation of the right greater splanchnic nerve for the m… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42257781 Insuffisance cardiaque Traitement symptomatique Publication PubMed Voir la publication source Heart failure with preserved ejection fraction (HFpEF) remains difficult to manage because conventional therapies often… The Egyptian heart journal : (EHJ) : official bulletin… 2026-11-08 04:37:54 Source
Incidence, medical therapy, and outcomes in heart failure with improv… Cordio System · PMID 42702264 Insuffisance cardiaque À vérifier Publication PubMed Voir la publication source To assess the incidence of heart failure with improved ejection fraction (HFimpEF) across guideline definitions (ACC/AH… American heart journal 2026-11-08 04:37:54 Source
Relationship Between the Azygos Vein and the Greater Splanchnic Nerve… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42249803 Insuffisance cardiaque À vérifier Publication PubMed Voir la publication source Although ablation of the greater splanchnic nerve is now being used to treat some patients with heart failure, the anat… Clinical anatomy (New York, N.Y.) 2026-11-08 04:37:54 Source
Validation of the PREVENT-HF Risk Prediction Equation in US Veterans. Cordio System · PMID 42969140 Insuffisance cardiaque À vérifier Publication PubMed Voir la publication source Résumé non disponible dans la base locale. Circulation 2026-11-08 04:37:54 Source
Changes in right ventricular-pulmonary artery coupling after transcat… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42822601 Insuffisance cardiaque À vérifier Publication PubMed Voir la publication source Right ventricular-pulmonary artery (RV-PA) coupling is an established marker of prognosis in mitral regurgitation (MR),… International journal of cardiology 2026-11-08 04:37:47 Source
Intraprocedural evaluation of residual mitral and tricuspid regurgita… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42982241 Maladie coronarienne À vérifier Publication PubMed Voir la publication source Transcatheter edge-to-edge repair (TEER) has emerged as an established therapeutic option for selected patients with se… International journal of cardiology 2026-11-08 04:37:47 Source
Tricuspid transcatheter edge-to-edge repair versus transcatheter tric… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42989943 Maladie coronarienne À vérifier Publication PubMed Voir la publication source Recent clinical studies of tricuspid transcatheter edge-to-edge repair (T-TEER) and transcatheter tricuspid valve repla… Current opinion in cardiology 2026-11-08 04:37:47 Source
Automated Production of Gene-Edited CAR-T Cells for People Living wit… RAPA-501 Autologous T stem cells · PMID 42847201 Cancer Thérapie cellulaire · Thérapie génique Publication PubMed Voir la publication source Adoptive transfer of gene-modified autologous T cells, for example, expressing chimeric antigen receptors (CARs), is a… Human gene therapy 2026-11-08 04:37:39 Source
Exploration — prudence

Pistes exploratoires 0

Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.

Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
Molécule / élément Maladie / population Objectif Phase / stade Statut / preuve Mécanisme / résumé Source Détail
Aucune piste exploratoire ne correspond aux filtres.