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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Sotatercept NCT07839585 · CHORUS — A Clinical Study of Sotatercept (MK-7962) in People With Combined Postc… | Insuffisance cardiaque | Thérapie génique | Phase 3 | NOT_YET_RECRUITING | Researchers are looking for other ways to treat people with combined postc… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:22 | Détail |
| Spironolactone Oral Suspension NCT06021860 · A Phase IV, Two-part, Open-label Study Assessing the Pharmacokinetics, Safety an… | Insuffisance cardiaque | À vérifier | Phase 4 | NOT_YET_RECRUITING | This is a 2-part, 2 periods per part, open-label study with spironolactone… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:22 | Détail |
| Synchronized Diaphragmatic Stimulation NCT06552637 · RECOVER-HF — Synchronized Diaphragmatic Stimulation in Symptomatic Heart Failure | Insuffisance cardiaque | Traitement symptomatique | Non applicable | RECRUITING | RECOVER HF is a clinical study designed to evaluate the safety and efficac… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:22 | Détail |
| VS-041 NCT07219511 · A Safety, Tolerability, and Biomarker Trial of VS-041 in Participants With Heart… | Insuffisance cardiaque | À vérifier | Phase 1 | ACTIVE_NOT_RECRUITING | A Safety, Tolerability, and Biomarker Trial of VS-041 in Participants with… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:22 | Détail |
| CRT-pacemaker device set to Routine Medical Therapy NCT03215849 · MAPPLE — Pacing in Heart Failure With Preserved LVEF | Insuffisance cardiaque | À vérifier | Non applicable | COMPLETED | A random-order cross-over pilot trial of a CE marked device (pacemaker) ou… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:21 | Détail |
| Furosemide Injection NCT05276219 · DECONGEST-AHF: Vasodilatation or Loop Diuretics in Acute Heart Failure | Insuffisance cardiaque | À vérifier | Phase 4 | RECRUITING | DECONGEST-AHF compares three initial treatments for adults admitted with s… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:21 | Détail |
| Blood, urinary and feces collection NCT06278519 · CARdiAc Mri and BiOLogical samplEs at the Acute Phase of a Myocardial Infarction… | Maladie coronarienne | Immunomodulation · Thérapie génique | Non applicable | COMPLETED | ST-Segment Elevation Myocardial infarction (STEMI) corresponding to acute… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:19 | Détail |
| Lead insertion NCT07820072 · SPIKE FLOW Endocardial Lead Safety and Performance Study | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | The objective of this study is to assess the safety and performance of the… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:19 | Détail |
| BioFreedom NCT02915107 · OCT STEMI SOIX — The SORT OUT IX STEMI OCT Trial | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | The aim of the Danish Organization for Randomized Trials with Clinical Out… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:18 | Détail |
| CytoSorb NCT05146336 · COSMOS — CytOSorb TreatMent Of Critically Ill PatientS Registry | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | Registry intended to provide a data repository and reporting infrastructur… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:18 | Détail |
| Ezetimibe 10mg NCT04701242 · Ezetimibe Utilization Early After Acute Myocardial Infarction, "EzAMI Trial" | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Rationale: Patients with acute coronary syndromes are at an increased risk… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:18 | Détail |
| Percutaneous Coronary Intervention NCT07887230 · iLITE, Clinical Performance of the Angiolite™ Drug-Eluting Stent | Maladie coronarienne | À vérifier | À vérifier | NOT_YET_RECRUITING | Prospective, multi-center, all comers, post market clinical follow-up (PMC… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:18 | Détail |
| Physiology-guided NCL PCI NCT05701358 · COMPLETE-2 — Physiology-guided vs Angiography-guided Non-culprit Lesion Complete… | Maladie coronarienne | À vérifier | Non applicable | ACTIVE_NOT_RECRUITING | COMPLETE-2 is a prospective, multi-centre, randomized controlled trial com… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:18 | Détail |
| Point-of-Care high-sensitivity troponin testing NCT06845826 · CERMIT — Point-of-Care Troponin Testing in the Emergency Department | Maladie coronarienne | Traitement symptomatique · Thérapie génique | Non applicable | ACTIVE_NOT_RECRUITING | The goal of this study is to evaluate whether a POC-guided testing strateg… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:18 | Détail |
| Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System NCT03471845 · RESOLUTE ONYX China Single Arm Study | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | It is a single arm clinical evaluation of safety and efficacy of the Medtr… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:18 | Détail |
| Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System NCT03466151 · RESOLUTE ONYX China RCT Study | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | It is a single arm clinical evaluation of safety and efficacy of the Medtr… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:18 | Détail |
| Arctic Front™ Cardiac Cryoablation Catheter NCT05227053 · STOP AF First Post-Approval Study | Maladie coronarienne | À vérifier | À vérifier | COMPLETED | The STOP AF First PAS is a prospective, global, multi-center, observationa… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:17 | Détail |
| Arctic Front™ Cardiac Cryoablation Catheter System NCT05005949 · STOP Persistent AF PAS | Maladie coronarienne | À vérifier | À vérifier | ACTIVE_NOT_RECRUITING | The STOP Persistent AF Post Approval Study (PAS) is a prospective, global,… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:17 | Détail |
| BAY3723113 NCT07023341 · CAMELLIA-HCM — A Study to Learn More About How Well Aficamten Works in Japanese… | Maladie coronarienne | Traitement symptomatique · Thérapie génique | Phase 3 | ACTIVE_NOT_RECRUITING | Researchers are looking for a better way to treat Japanese people who have… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:17 | Détail |
| FARAPULSE Pulsed Field Ablation System NCT06808217 · OPALISE — A Registry on the FARAVIEW Technology of the OPAL HDx Mapping System W… | Maladie coronarienne | À vérifier | À vérifier | ACTIVE_NOT_RECRUITING | The study is designed to collect data on the acute and long-term (1 year)… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:17 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effects of continuous vs. intermittent transcutaneous electrical stim… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 41866984 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source To compare the effects of two transcutaneous electrical stimulation (TES) patterns applied to the auricular branches of… | Cranio : the journal of craniomandibular practice 2026-11-08 04:38:07 | Source |
| Optimizing Percutaneous Tibial Nerve Stimulation Intensity for Overac… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42554545 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source Overactive bladder (OAB) is a significant global health issue. The standard percutaneous tibial nerve stimulation (PTNS… | Neuromodulation : journal of the International Neuromo… 2026-11-08 04:38:07 | Source |
| Transcutaneous auricular vagus nerve stimulation improves dysautonomi… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42802247 | Maladie rénale chronique | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Autonomic nervous system dysfunction is highly prevalent in hypermobile Ehlers-Danlos syndrome (hEDS) and contributes s… | Neurological sciences : official journal of the Italia… 2026-11-08 04:38:07 | Source |
| Factors associated with high-flow therapy failure in COVID-19-related… Non-Invasive Positive Pressure Ventilation · PMID 42888091 | Maladie rénale chronique | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source The optimal selection of non-invasive respiratory support for patients with COVID-19-related acute hypoxemic respirator… | Enfermedades infecciosas y microbiologia clinica (Engl… 2026-11-08 04:38:06 | Source |
| High-Flow Nasal Cannula in Adult Acute Care: Physiological Mechanisms… Non-Invasive Positive Pressure Ventilation · PMID 42942512 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source High-flow nasal cannula (HFNC) oxygen therapy is widely used in emergency, intensive care, perioperative, and procedura… | Medicina (Kaunas, Lithuania) 2026-11-08 04:38:06 | Source |
| Impact of respiratory support on time to achieve full oral feeding in… Non-Invasive Positive Pressure Ventilation · PMID 42871336 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source Very low birth weight infants often require respiratory support, which may delay full oral feeding. The independent rol… | Frontiers in pediatrics 2026-11-08 04:38:06 | Source |
| A comparative analysis of 3MAX aspiration versus 3 mm Trevo Retriever… Thromboaspiration catheter · PMID 31243066 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Although aspiration and stent retriever thrombectomy perform similarly in proximal occlusions, no comparative series ar… | Journal of neurointerventional surgery 2026-11-08 04:38:02 | Source |
| Percutaneous Pulmonary Thrombectomy Beyond Acute Pulmonary Embolism:… Thromboaspiration catheter · PMID 38385241 | Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Subacute massive pulmonary embolism is an uncommon manifestation of severe pulmonary embolism associated with poor prog… | Journal of endovascular therapy : an official journal… 2026-11-08 04:38:02 | Source |
| Simplified classification of cavernous internal carotid artery tortuo… Thromboaspiration catheter · PMID 35475775 | Hypertension artérielle · Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Thromboaspiration catheters are increasingly used for the endovascular treatment of large vessel stroke (LVS), while to… | Neurological research 2026-11-08 04:38:02 | Source |
| Multifocal continuous theta burst stimulation in idiopathic generaliz… Continuous Theta Burst Stimulation (cTBS) · PMID 42731195 | Accident vasculaire cérébral | Traitement symptomatique | Publication | PubMed | Voir la publication source Idiopathic generalized epilepsy (IGE) is a disorder of the cortico-subcortical networks. Continuous theta burst stimula… | Clinical neurophysiology : official journal of the Int… 2026-11-08 04:38:00 | Source |
| Optimizing brain functional-structural architecture with cTBS to redu… Continuous Theta Burst Stimulation (cTBS) · PMID 42457860 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Alcohol use disorder (AUD) is characterized by high relapse rates, necessitating novel interventions. Continuous theta-… | Molecular psychiatry 2026-11-08 04:38:00 | Source |
| Digital Outreach to Improve Statin Refills in Patients With Low Stati… Cordio System · PMID 42667613 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Statin nonadherence is a leading, addressable driver of preventable cardiovascular events. Although health systems rout… | JAMA 2026-11-08 04:37:54 | Source |
| Endovascular ablation of the right greater splanchnic nerve for the m… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42257781 | Insuffisance cardiaque | Traitement symptomatique | Publication | PubMed | Voir la publication source Heart failure with preserved ejection fraction (HFpEF) remains difficult to manage because conventional therapies often… | The Egyptian heart journal : (EHJ) : official bulletin… 2026-11-08 04:37:54 | Source |
| Incidence, medical therapy, and outcomes in heart failure with improv… Cordio System · PMID 42702264 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source To assess the incidence of heart failure with improved ejection fraction (HFimpEF) across guideline definitions (ACC/AH… | American heart journal 2026-11-08 04:37:54 | Source |
| Relationship Between the Azygos Vein and the Greater Splanchnic Nerve… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42249803 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Although ablation of the greater splanchnic nerve is now being used to treat some patients with heart failure, the anat… | Clinical anatomy (New York, N.Y.) 2026-11-08 04:37:54 | Source |
| Validation of the PREVENT-HF Risk Prediction Equation in US Veterans. Cordio System · PMID 42969140 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Circulation 2026-11-08 04:37:54 | Source |
| Changes in right ventricular-pulmonary artery coupling after transcat… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42822601 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Right ventricular-pulmonary artery (RV-PA) coupling is an established marker of prognosis in mitral regurgitation (MR),… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Intraprocedural evaluation of residual mitral and tricuspid regurgita… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42982241 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Transcatheter edge-to-edge repair (TEER) has emerged as an established therapeutic option for selected patients with se… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Tricuspid transcatheter edge-to-edge repair versus transcatheter tric… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42989943 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Recent clinical studies of tricuspid transcatheter edge-to-edge repair (T-TEER) and transcatheter tricuspid valve repla… | Current opinion in cardiology 2026-11-08 04:37:47 | Source |
| Automated Production of Gene-Edited CAR-T Cells for People Living wit… RAPA-501 Autologous T stem cells · PMID 42847201 | Cancer | Thérapie cellulaire · Thérapie génique | Publication | PubMed | Voir la publication source Adoptive transfer of gene-modified autologous T cells, for example, expressing chimeric antigen receptors (CARs), is a… | Human gene therapy 2026-11-08 04:37:39 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||