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Toutes les maladies
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ramipril tablet NCT07879560 · ADMA /PedsQL — Ramipril vs. Amlodipine in Pediatric Hemodialysis Patients | Maladie rénale chronique | Thérapie génique | Phase 3 | NOT_YET_RECRUITING | The goal of this clinical trial is to learn if Ramipril works better than… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:31 | Détail |
| Sham treatment NCT05757557 · DEFENDER — Perioperative Nitric Oxide Prevents Acute Kidney Injury in Cardiac Su… | Maladie rénale chronique | Ralentissement de la progression · Traitement symptomatique | Phase 1/2 | COMPLETED | The aim of the study was to investigate the effectiveness of Manual Therap… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:31 | Détail |
| Sodium bicarbonate NCT05113641 · Reducing Dietary Acid With Food Versus Oral Alkali in People With Chronic Kidney… | Maladie rénale chronique | À vérifier | Non applicable | COMPLETED | Metabolic acidosis is a common problem that occurs with worsening chronic… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:31 | Détail |
| Sotagliflozin initiation NCT07325201 · SCOUT-CKD — Mitigating DKA in Type 1 Diabetes for Safe Use of SGLT Inhibitors Us… | Maladie rénale chronique | À vérifier | Phase 2 | NOT_YET_RECRUITING | The goal of this clinical trial is to develop and evaluate a novel diabete… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:31 | Détail |
| Spironolactone NCT07888504 · Low-Dose Spironolactone in Hemodialysis Patients With Resistant Hypertension | Maladie rénale chronique | Immunomodulation | Phase 4 | COMPLETED | Many patients on hemodialysis have high blood pressure that does not respo… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:31 | Détail |
| Apixaban NCT07609654 · OASIS-AF — Oral Anticoagulation in Patients With Prior Deep Intracerebral Hemorr… | Accident vasculaire cérébral | Traitement symptomatique | Phase 4 | NOT_YET_RECRUITING | This trial aims to compare the safety and efficacy of apixaban alone versu… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:27 | Détail |
| Best medical management NCT06101667 · Efficacy and Safety of Endovascular Recanalization for Acute Basilar Artery Occl… | Accident vasculaire cérébral | À vérifier | Non applicable | ACTIVE_NOT_RECRUITING | The aim of this study is to assess the efficacy and safety of endovascular… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:27 | Détail |
| Combined (Robotic balance training and high-definition transcranial d… NCT07113041 · NEUROBALANCE — Neuromodulation-Enhanced Use of RObotic BALANCE Training to Impro… | Accident vasculaire cérébral | À vérifier | Non applicable | RECRUITING | Our proposed study, "NEUROBALANCE Stroke,"; aims to evaluate the effective… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:27 | Détail |
| Edaravone NCT00200356 · Edaravone-Sodium Ozagrel Comparative Post-Marketing Study on Acute Ischemic Stro… | Accident vasculaire cérébral | À vérifier | Phase 4 | COMPLETED | This study is randomized, Sodium Ozagrel (Thromboxane A2 Synthase Inhibito… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:27 | Détail |
| Haptic-assisted virtual reality training (Bimeo PRO) NCT07882810 · CR-4-Health-VR — Haptic-Assisted Virtual Reality Upper-Limb Rehabilitation After… | Accident vasculaire cérébral | Ralentissement de la progression | Non applicable | NOT_YET_RECRUITING | After spontaneous intracerebral haemorrhage (ICH), many survivors have per… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:27 | Détail |
| Mechanical thrombectomy combined with ischemic post-conditioning NCT05789823 · Ischemic Post-conditioning in Acute Ischemic Stroke Thrombectomy (PROTECT-2) | Accident vasculaire cérébral | Neuroprotection | Phase 2 | COMPLETED | Ischemic post-conditioning is a neuroprotective strategy that has been pro… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:27 | Détail |
| MLC901 NCT07828210 · NAiD-PRO — NeuroAiD Patient-Reported Outcomes in Patients With Mild to Moderate… | Accident vasculaire cérébral | À vérifier | Phase 4 | RECRUITING | This is a randomized, controlled, open-label study of MLC901 (NeuroAiD™ II… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:27 | Détail |
| Penumbra System ® NCT07107022 · i-RISE — Study to Collect Real-world Performance and Safety Data on Penumbra Sys… | Accident vasculaire cérébral | À vérifier | À vérifier | RECRUITING | The primary objective of this study is to collect real-world performance a… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:27 | Détail |
| RapidPulseTM Aspiration System NCT06029491 · TURBO — Thrombectomy Using Pulsed Aspiration for Reperfusion of Brain Occlusions | Accident vasculaire cérébral | Traitement symptomatique | Non applicable | RECRUITING | The goal of this clinical trials is to demonstrate the safety and effectiv… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:27 | Détail |
| Tenecteplase NCT06320431 · ACT-GLOBAL THROMBOLYSIS (ACT-WHEN-001) Domain Within the ACT-GLOBAL Adaptive Pla… | Accident vasculaire cérébral | Ralentissement de la progression | Phase 3 | RECRUITING | This study is open to adults who had an acute stroke caused by a clot bloc… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:27 | Détail |
| Tenecteplase or Alteplase- depending upon availability at each treati… NCT07687056 · ACT-GLOBAL IA Thrombolysis(ACT-REACT-004)Domain Within the ACT-GLOBAL Adaptive P… | Accident vasculaire cérébral | À vérifier | Phase 3 | RECRUITING | Study Design and Duration: This domain will be conducted as part of ACT-GL… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:27 | Détail |
| Vision Training and Learning Task NCT06578117 · Statistical Learning as a Novel Intervention for Cortical Blindness | Accident vasculaire cérébral | À vérifier | Non applicable | ACTIVE_NOT_RECRUITING | This project aims to develop a novel visual training paradigm for use in v… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:27 | Détail |
| Edoxaban 15 mg NCT07454707 · Testing a New Treatment Strategy to Improve Secondary Stroke Prevention for Olde… | Accident vasculaire cérébral | Traitement symptomatique | Phase 3 | RECRUITING | The overall aim of this research is to improve secondary stroke prevention… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:26 | Détail |
| Electrocardiogram NCT05683873 · Stroke-induced Myocardial Dysfunction: Role of GDF-15 (SMOG-15) Clinical Work Pa… | Accident vasculaire cérébral | Traitement symptomatique | À vérifier | RECRUITING | The aim of this study is to analyze the relationship between the blood bio… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:26 | Détail |
| FES therapy NCT07889921 · TECAR and FES for Hand Function in Post-Stroke Spasticity | Accident vasculaire cérébral | Traitement symptomatique | Non applicable | COMPLETED | Upper-limb spasticity and impaired hand function are experienced by up to… À vérifier | ClinicalTrials.gov 2026-10-25 04:37:26 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effects of continuous vs. intermittent transcutaneous electrical stim… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 41866984 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source To compare the effects of two transcutaneous electrical stimulation (TES) patterns applied to the auricular branches of… | Cranio : the journal of craniomandibular practice 2026-11-08 04:38:07 | Source |
| Optimizing Percutaneous Tibial Nerve Stimulation Intensity for Overac… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42554545 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source Overactive bladder (OAB) is a significant global health issue. The standard percutaneous tibial nerve stimulation (PTNS… | Neuromodulation : journal of the International Neuromo… 2026-11-08 04:38:07 | Source |
| Transcutaneous auricular vagus nerve stimulation improves dysautonomi… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42802247 | Maladie rénale chronique | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Autonomic nervous system dysfunction is highly prevalent in hypermobile Ehlers-Danlos syndrome (hEDS) and contributes s… | Neurological sciences : official journal of the Italia… 2026-11-08 04:38:07 | Source |
| Factors associated with high-flow therapy failure in COVID-19-related… Non-Invasive Positive Pressure Ventilation · PMID 42888091 | Maladie rénale chronique | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source The optimal selection of non-invasive respiratory support for patients with COVID-19-related acute hypoxemic respirator… | Enfermedades infecciosas y microbiologia clinica (Engl… 2026-11-08 04:38:06 | Source |
| High-Flow Nasal Cannula in Adult Acute Care: Physiological Mechanisms… Non-Invasive Positive Pressure Ventilation · PMID 42942512 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source High-flow nasal cannula (HFNC) oxygen therapy is widely used in emergency, intensive care, perioperative, and procedura… | Medicina (Kaunas, Lithuania) 2026-11-08 04:38:06 | Source |
| Impact of respiratory support on time to achieve full oral feeding in… Non-Invasive Positive Pressure Ventilation · PMID 42871336 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source Very low birth weight infants often require respiratory support, which may delay full oral feeding. The independent rol… | Frontiers in pediatrics 2026-11-08 04:38:06 | Source |
| A comparative analysis of 3MAX aspiration versus 3 mm Trevo Retriever… Thromboaspiration catheter · PMID 31243066 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Although aspiration and stent retriever thrombectomy perform similarly in proximal occlusions, no comparative series ar… | Journal of neurointerventional surgery 2026-11-08 04:38:02 | Source |
| Percutaneous Pulmonary Thrombectomy Beyond Acute Pulmonary Embolism:… Thromboaspiration catheter · PMID 38385241 | Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Subacute massive pulmonary embolism is an uncommon manifestation of severe pulmonary embolism associated with poor prog… | Journal of endovascular therapy : an official journal… 2026-11-08 04:38:02 | Source |
| Simplified classification of cavernous internal carotid artery tortuo… Thromboaspiration catheter · PMID 35475775 | Hypertension artérielle · Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Thromboaspiration catheters are increasingly used for the endovascular treatment of large vessel stroke (LVS), while to… | Neurological research 2026-11-08 04:38:02 | Source |
| Multifocal continuous theta burst stimulation in idiopathic generaliz… Continuous Theta Burst Stimulation (cTBS) · PMID 42731195 | Accident vasculaire cérébral | Traitement symptomatique | Publication | PubMed | Voir la publication source Idiopathic generalized epilepsy (IGE) is a disorder of the cortico-subcortical networks. Continuous theta burst stimula… | Clinical neurophysiology : official journal of the Int… 2026-11-08 04:38:00 | Source |
| Optimizing brain functional-structural architecture with cTBS to redu… Continuous Theta Burst Stimulation (cTBS) · PMID 42457860 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Alcohol use disorder (AUD) is characterized by high relapse rates, necessitating novel interventions. Continuous theta-… | Molecular psychiatry 2026-11-08 04:38:00 | Source |
| Digital Outreach to Improve Statin Refills in Patients With Low Stati… Cordio System · PMID 42667613 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Statin nonadherence is a leading, addressable driver of preventable cardiovascular events. Although health systems rout… | JAMA 2026-11-08 04:37:54 | Source |
| Endovascular ablation of the right greater splanchnic nerve for the m… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42257781 | Insuffisance cardiaque | Traitement symptomatique | Publication | PubMed | Voir la publication source Heart failure with preserved ejection fraction (HFpEF) remains difficult to manage because conventional therapies often… | The Egyptian heart journal : (EHJ) : official bulletin… 2026-11-08 04:37:54 | Source |
| Incidence, medical therapy, and outcomes in heart failure with improv… Cordio System · PMID 42702264 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source To assess the incidence of heart failure with improved ejection fraction (HFimpEF) across guideline definitions (ACC/AH… | American heart journal 2026-11-08 04:37:54 | Source |
| Relationship Between the Azygos Vein and the Greater Splanchnic Nerve… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42249803 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Although ablation of the greater splanchnic nerve is now being used to treat some patients with heart failure, the anat… | Clinical anatomy (New York, N.Y.) 2026-11-08 04:37:54 | Source |
| Validation of the PREVENT-HF Risk Prediction Equation in US Veterans. Cordio System · PMID 42969140 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Circulation 2026-11-08 04:37:54 | Source |
| Changes in right ventricular-pulmonary artery coupling after transcat… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42822601 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Right ventricular-pulmonary artery (RV-PA) coupling is an established marker of prognosis in mitral regurgitation (MR),… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Intraprocedural evaluation of residual mitral and tricuspid regurgita… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42982241 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Transcatheter edge-to-edge repair (TEER) has emerged as an established therapeutic option for selected patients with se… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Tricuspid transcatheter edge-to-edge repair versus transcatheter tric… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42989943 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Recent clinical studies of tricuspid transcatheter edge-to-edge repair (T-TEER) and transcatheter tricuspid valve repla… | Current opinion in cardiology 2026-11-08 04:37:47 | Source |
| Automated Production of Gene-Edited CAR-T Cells for People Living wit… RAPA-501 Autologous T stem cells · PMID 42847201 | Cancer | Thérapie cellulaire · Thérapie génique | Publication | PubMed | Voir la publication source Adoptive transfer of gene-modified autologous T cells, for example, expressing chimeric antigen receptors (CARs), is a… | Human gene therapy 2026-11-08 04:37:39 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||