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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Causal relationship between epigenetic markers and type 2 diabetes in… Genetics of Type 2 Diabetes in West Africans · PMID 42032377 | Hypertension artérielle | Thérapie génique | Publication | PubMed | Voir la publication source Evidence for a causal role of DNA methylation sites (CpGs) in type 2 diabetes and glycaemic traits is limited due to th… | Diabetologia 2026-08-16 13:13:31 | Source |
| Epigenome-wide analysis in West Africans identifies DNA methylation m… Genetics of Type 2 Diabetes in West Africans · PMID 41793944 | Hypertension artérielle | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Adiponectin is a circulating adipokine involved in energy metabolism and inflammation, with reported protective effects… | EBioMedicine 2026-08-16 13:13:31 | Source |
| Integration of clinical and proteomic risk factors enhances prognosti… Genetics of Type 2 Diabetes in West Africans · PMID 41559749 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source BACKGROUND: Type 2 diabetes complications manifest across various organs, but are fundamentally rooted in vascular dysf… | Cardiovascular diabetology 2026-08-16 13:13:31 | Source |
| Exploring the role of social media and online communities in the infe… Impact of Online Medical Misinformation · PMID 41999203 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Infertility is a global health challenge with profound psychosocial consequences. Couples navigate this journey within… | Journal of psychosomatic obstetrics and gynaecology 2026-08-16 13:13:30 | Source |
| Impact of faculty and resident gender on milestone evaluations in ane… Impact of Online Medical Misinformation · PMID 42429203 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Anesthesia-specific milestone evaluations are intended to objectively assess performance in ACGME core competencies for… | Medical education online 2026-08-16 13:13:30 | Source |
| Leveraging near-peer teaching: the impact of cognitive and social con… Impact of Online Medical Misinformation · PMID 42157464 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Equipping future clinicians to recognize and reverse opioid overdoses requires experiential training and access to nalo… | Medical education online 2026-08-16 13:13:30 | Source |
| Effects of air pollution on disease activity in patients with rheumat… BATHE-Family Medicine · PMID 42557168 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source This study aimed to evaluate the associations of air pollution with disease activity and flare rate in patients with rh… | Annals of the rheumatic diseases 2026-08-16 13:13:29 | Source |
| Carotid body excision significantly changes ventilatory control in aw… Carotid body excision · PMID 3372424 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source We determined the effects of carotid body excision (CBX) on eupneic ventilation and the ventilatory responses to acute… | Journal of applied physiology (Bethesda, Md. : 1985) 2026-08-16 13:13:25 | Source |
| Effects of carotid body excision on recovery of respiratory function… Carotid body excision · PMID 15919075 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source In a previous study, we described the spontaneous recovery of respiratory motor function in adult rats subjected to a l… | Experimental neurology 2026-08-16 13:13:25 | Source |
| The effects of unilateral carotid body excision on ventilatory contro… Carotid body excision · PMID 6672918 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source The purpose of this study was to determine whether or not unilateral carotid body excision (UCBE) alters normal respira… | Respiration physiology 2026-08-16 13:13:25 | Source |
| Ectopic ACTH-dependent Cushing syndrome in 3 hospitalized patients: l… Osilodrostat · PMID 42591670 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Severe Cushing syndrome (CS) is a rare diagnosis with high mortality, which limits the ability of endocrinologists to g… | JCEM case reports 2026-08-16 13:13:24 | Source |
| Is Hypercortisolism Treatable? Which Patients Should Be Treated and H… Osilodrostat · PMID 42533758 | Hypertension artérielle | Thérapie génique | Publication | PubMed | Voir la publication source To provide a practical guide on when to suspect endogenous hypercortisolism, how to use the overnight 1-mg dexamethason… | Diabetes, obesity & metabolism 2026-08-16 13:13:24 | Source |
| Protracted osilodrostat-induced pan-adrenal steroidogenic suppression… Osilodrostat · PMID 42494874 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Osilodrostat, a potent 11β-hydroxylase inhibitor, is used for Cushing syndrome. Transient adrenal insufficiency during… | JCEM case reports 2026-08-16 13:13:24 | Source |
| Association between orthostatic blood pressure change and masked and… Home BP · PMID 42267569 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Exaggerated blood pressure (BP) response to orthostatic stimuli is indicative of cardiovascular frailty and may be asso… | Journal of hypertension 2026-08-16 13:13:23 | Source |
| Bu-Sui-Dan promotes angiogenesis to mitigate age-related osteoporosis… CBP · PMID 42364672 | Hypertension artérielle | Thérapie génique | Publication | PubMed | Voir la publication source Bu-Sui-Dan (BSD) is a traditional Chinese medicine formulation first recorded in the Song Dynasty text Shi Zhai Bai Yi… | Journal of ethnopharmacology 2026-08-16 13:13:23 | Source |
| Measurement of blood pressure in European Society of Hypertension Exc… Home BP · PMID 41855474 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Office blood pressure (BP) measurement is the cornerstone of hypertension diagnosis and risk stratification. Inaccurate… | Blood pressure 2026-08-16 13:13:23 | Source |
| Reassessing blood pressure control: the role of long-term blood press… Home BP · PMID 41924975 | Hypertension artérielle · Insuffisance cardiaque · Accident vasculair… | À vérifier | Publication | PubMed | Voir la publication source This review summarizes current evidence on visit-to-visit blood pressure variability (BPV) and blood pressure time in t… | Blood pressure 2026-08-16 13:13:23 | Source |
| Targeted discovery of anti-skin aging peptides from Camelus bactrianu… CBP · PMID 42302941 | Hypertension artérielle | Immunomodulation | Publication | PubMed | Voir la publication source Placenta has historically been utilized as a therapeutic agent in traditional medicine, notably as "Ziheche" in traditi… | Journal of ethnopharmacology 2026-08-16 13:13:23 | Source |
| Unlocking raw-corncob consolidated bioprocessing for malic acid produ… CBP · PMID 42604004 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source l-Malic acid is an important C4 platform chemical, but its direct production from raw lignocellulosic biomass by consol… | Synthetic and systems biotechnology 2026-08-16 13:13:23 | Source |
| Association of Anxiety with Discrepancies Between Unattended and Atte… uAOBP · PMID 40319364 | Hypertension artérielle | Thérapie génique | Publication | PubMed | Voir la publication source Precision of blood pressure (BP) measurements is crucial in hypertension care. Conventional office measurements (OBP) a… | American journal of hypertension 2026-08-16 13:13:22 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||