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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Lead-induced apoptosis in Sertoli cells is associated with Ca dysregu… Labetalol or Nifedipine · PMID 42492755 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Lead (Pb) is a common environmental toxicant associated with male reproductive injury. Sertoli cells (SCs) are essentia… | Food and chemical toxicology : an international journa… 2026-08-16 13:13:59 | Source |
| Transient conductive hearing loss as a notable and rare manifestation… Labetalol or Nifedipine · PMID 41582066 | Hypertension artérielle | Immunomodulation · Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source To report a case of transient conductive hearing loss secondary to secretory otitis media (SOM) in a patient with preec… | The journal of maternal-fetal & neonatal medicine : th… 2026-08-16 13:13:59 | Source |
| VA-ECMO and HIET for toxic cardiogenic shock in an elderly patient fo… Labetalol or Nifedipine · PMID 42434173 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source This case report presents the successful use of high-dose insulin euglycemic therapy (HIET) and venous arterial extraco… | Toxicology reports 2026-08-16 13:13:59 | Source |
| A Randomized Feasibility Trial of a Multicomponent Quality Improvemen… Fixed-Dose Combinations Pragmatic Randomized Implementation Trial for Blood Pressure Control ·… | Insuffisance cardiaque · Maladie coronarienne · Accident vasculaire c… | Ralentissement de la progression | Publication | PubMed | Voir la publication source Chronic cardiovascular diseases (CVD) care quality remains suboptimal, globally. This study evaluated the feasibility a… | medRxiv : the preprint server for health sciences 2026-08-16 13:13:58 | Source |
| Frontiers of cardiovascular polypills: From atherosclerosis and beyon… Fixed-Dose Combinations Pragmatic Randomized Implementation Trial for Blood Pressure Control ·… | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Fixed-dose combination (FDC) therapies (also known as polypills) remain underutilized in clinical practice despite over… | Trends in cardiovascular medicine 2026-08-16 13:13:58 | Source |
| Evaluation of Polygenic Scores and CT Imaging in Risk Factor Modifica… Nurse-Led Motivational Interviewing for Blood Pressure Control · PMID 42223325 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source The contemporary management of type 2 diabetes (T2D) involves a multifaceted model of care integrating intensive manage… | Clinical cardiology 2026-08-16 13:13:53 | Source |
| Cardiometabolic benefits of parathyroidectomy in dialysis patients wi… OCORO — Study of the Progression of Chronic Cardiovascular Conditions · PMID 42338091 | Hypertension artérielle | Ralentissement de la progression · Immunomodulation | Publication | PubMed | Voir la publication source Secondary hyperparathyroidism (SHPT) contributes to mineral-bone disorders, chronic inflammation, and adverse cardiomet… | Renal failure 2026-08-16 13:13:50 | Source |
| Pentoxifylline and cardiorenal outcomes in advanced CKD with untreate… OCORO — Study of the Progression of Chronic Cardiovascular Conditions · PMID 42393494 | Maladie rénale chronique | Ralentissement de la progression · Immunomodulation | Publication | PubMed | Voir la publication source Patients with advanced chronic kidney disease (CKD) and dyslipidemia are at high risk of kidney failure and cardiovascu… | Renal failure 2026-08-16 13:13:50 | Source |
| The impact of multiple long-term conditions on mortality, progression… OCORO — Study of the Progression of Chronic Cardiovascular Conditions · PMID 42334309 | Hypertension artérielle · Maladie rénale chronique | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Multiple long-term conditions (MLTC) are common in people with chronic kidney disease (CKD). This study examined the im… | Annals of medicine 2026-08-16 13:13:50 | Source |
| Exploring Interprofessional Primary Care (IPPC) teams' impact on chro… Team-based shared decision-making · PMID 42542561 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Interprofessional care involves two or more professionals from different disciplines working in partnership to achieve… | Journal of interprofessional care 2026-08-16 13:13:49 | Source |
| Interprofessional education in pharmacy: Bridging collaborative compe… Team-based shared decision-making · PMID 42019190 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Interprofessional education (IPE) has been widely adopted in pharmacy education to enhance collaborative competencies a… | Currents in pharmacy teaching & learning 2026-08-16 13:13:49 | Source |
| Rethinking obesity management targets: Findings from an international… Team-based shared decision-making · PMID 42602889 | Hypertension artérielle | Thérapie génique | Publication | PubMed | Voir la publication source Obesity is a chronic disease that requires individualized, person-centred care beyond traditional weight-centric target… | Obesity pillars 2026-08-16 13:13:49 | Source |
| Feasibility and Acceptability of a Novel Algorithm for Physicians to… P3-EX — A Novel Digital Tool Physicians Can Use to Prescribe Exercise to Patients With Cardiov… | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Approximately half of U.S. adults have ≥1 cardiovascular disease (CVD) risk factors. Exercise is universally recommende… | Healthcare (Basel, Switzerland) 2026-08-16 13:13:46 | Source |
| Digital Health Monitoring and Intervention Suite for Stress in Frontl… Assessing the Feasibility of the "Heart Care Pairs" Intervention · PMID 42275639 | Hypertension artérielle | Traitement symptomatique | Publication | PubMed | Voir la publication source Stress among health care workers (HCWs) contributes to burnout, workforce attrition, and adverse patient outcomes. Alth… | JMIR formative research 2026-08-16 13:13:44 | Source |
| Feasibility and preliminary efficacy of a 12-week primary care-based… Assessing the Feasibility of the "Heart Care Pairs" Intervention · PMID 41851425 | Hypertension artérielle | Traitement symptomatique | Publication | PubMed | Voir la publication source Physical activity (PA) and dietary counseling are recommended for adults with cardiovascular disease (CVD) risk factors… | Journal of behavioral medicine 2026-08-16 13:13:44 | Source |
| Frailty Status and Outcomes in Patients with Acute Coronary Syndrome… Assessing the Feasibility of the "Heart Care Pairs" Intervention · PMID 42411588 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Frailty is increasingly recognised as an age-independent predictor of adverse outcomes in cardiovascular disease, yet i… | European journal of cardiovascular nursing 2026-08-16 13:13:44 | Source |
| Home blood pressure-guided antihypertensive therapy in chronic kidney… Conventional office blood pressure-guided management · PMID 29459219 | Hypertension artérielle · Maladie rénale chronique | Ralentissement de la progression | Publication | PubMed | Voir la publication source In the era of newly introduced hypertension guidelines recommending lower blood pressure (BP) targets for drug-treated… | Journal of the American Society of Hypertension : JASH 2026-08-16 13:13:42 | Source |
| A randomized controlled trial comparing the efficacy of nifedipine an… Comparator Nifedipine 30 mg Extended-Release · PMID 37806651 | Hypertension artérielle | Thérapie génique | Publication | PubMed | Voir la publication source Postpartum hypertension is a common medical complication of pregnancy and is associated with increased healthcare use,… | American journal of obstetrics & gynecology MFM 2026-08-16 13:13:35 | Source |
| Comparative efficacy of generic nifedipine versus brand-name amlodipi… Comparator Nifedipine 30 mg Extended-Release · PMID 35674192 | Hypertension artérielle · Insuffisance cardiaque · Maladie coronarien… | À vérifier | Publication | PubMed | Voir la publication source The control rate of hypertension remains concerning, indicating the requirement for better management strategies. The c… | Journal of clinical hypertension (Greenwich, Conn.) 2026-08-16 13:13:35 | Source |
| Trial of Intrapartum Extended-Release Nifedipine to Prevent Severe Hy… Comparator Nifedipine 30 mg Extended-Release · PMID 36189646 | Hypertension artérielle | Thérapie génique | Publication | PubMed | Voir la publication source Preeclampsia is associated with maternal and perinatal morbidity. Besides acute therapy for severe hypertension, best p… | Hypertension (Dallas, Tex. : 1979) 2026-08-16 13:13:35 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||