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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Comparative Analysis of the LOBO Device and Coils for Proximal Spleni… Proximal Splenic Artery Embolization · PMID 42118299 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source To evaluate the technical and clinical efficacy of the low-profile braided occluder (LOBO) device for proximal splenic… | Cardiovascular and interventional radiology 2026-08-16 13:14:08 | Source |
| Efficacy and safety of extravascular renal denervation in patients wi… HyperQure Renal Denervation System · PMID 42112516 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Although catheter-based renal denervation (RDN) has emerged as a potential treatment for resistant hypertension, it has… | Clinical hypertension 2026-08-16 13:14:08 | Source |
| Incidental intrahepatic cholangiocarcinoma detected in the explant li… Proximal Splenic Artery Embolization · PMID 42043748 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Living-donor liver transplantation (LDLT) is considered for polycystic liver disease (PLD) with portal hypertension or… | Clinical journal of gastroenterology 2026-08-16 13:14:08 | Source |
| Long-term outcomes following radiofrequency renal denervation: meta-a… HyperQure Renal Denervation System · PMID 40676971 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Radiofrequency (RF) renal denervation (RDN) safely lowers office and 24-h blood pressure (BP). This meta-analysis exami… | European journal of preventive cardiology 2026-08-16 13:14:08 | Source |
| Splenic Artery Embolization for Refractory Ascites Following Hepatect… Proximal Splenic Artery Embolization · PMID 42023205 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Surgery (Resection/Liver transplant) remains the only curative modality for the treatment of hepatocellular carcinoma (… | Indian journal of surgical oncology 2026-08-16 13:14:08 | Source |
| Natriuretic response to an acute oral potassium load in healthy indiv… K+ in CKD — Potassium Supplementation in CKD · PMID 41288308 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source The health benefits of dietary potassium have been linked to potassium-induced natriuresis. However, it is unknown whet… | Nephrology, dialysis, transplantation : official publi… 2026-08-16 13:14:07 | Source |
| The "FIFTY SHADOWS" of the RALES Trial: Lessons about the Potential R… K+ in CKD — Potassium Supplementation in CKD · PMID 35887733 | Hypertension artérielle · Maladie rénale chronique | Ralentissement de la progression | Publication | PubMed | Voir la publication source Hyperkalaemia (HK) is one of the most common electrolyte disorders and a frequent reason for nephrological consultation… | Journal of clinical medicine 2026-08-16 13:14:07 | Source |
| The Effect of Omega-3 Supplements on Renal Function Indices in Chroni… K+ in CKD — Potassium Supplementation in CKD · PMID 40584465 | Hypertension artérielle · Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source Recent studies reported that omega-3 fatty acids may improve renal function in patients with chronic kidney disease (CK… | Nutrition and metabolic insights 2026-08-16 13:14:07 | Source |
| An expert consensus statement on renal denervation for the management… HyperQureTM Renal Denervation (RDN) System: · PMID 42372819 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source This national expert consensus statement, endorsed by the Portuguese Association of Interventional Cardiology of the Po… | Revista portuguesa de cardiologia : orgao oficial da S… 2026-08-16 13:14:06 | Source |
| AI-assisted Python automation of mean-centering spectrophotometric me… Amlodipine · PMID 42372323 | Hypertension artérielle · Myopathies · Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source The simultaneous spectrophotometric determination of drugs with overlapping spectra remains a challenging analytical ta… | Spectrochimica acta. Part A, Molecular and biomolecula… 2026-08-16 13:14:05 | Source |
| Design-Assisted Chemometric UV Spectrophotometric Determination of Ca… Amlodipine · PMID 42487652 | Hypertension artérielle · Myopathies · Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source This study presents a sustainable chemometric-assisted UV spectrophotometric strategy for the simultaneous determinatio… | Analytical science advances 2026-08-16 13:14:05 | Source |
| Research progress on the role and mechanism of STIM and Orai protein-… Amlodipine · PMID 42503223 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Store-operated calcium entry (SOCE) mediated by STIM and Orai proteins is a fundamental Ca influx mechanism that critic… | Channels (Austin, Tex.) 2026-08-16 13:14:05 | Source |
| Determination of five antihypertensives in dried capillary plasma spo… Losartan · PMID 42177855 | Hypertension artérielle | Thérapie génique | Publication | PubMed | Voir la publication source Adherence to hypertension treatment is crucial for therapeutic success, as noncompliance adversely affects quality of l… | Journal of pharmaceutical and biomedical analysis 2026-08-16 13:14:02 | Source |
| Mechanisms of obesogenic adipocyte signaling in mouse 3T3-L1 cells in… Losartan · PMID 42388457 | Hypertension artérielle | Thérapie génique | Publication | PubMed | Voir la publication source Recent studies have demonstrated a strong correlation between exposure to traffic-generated air pollutants and the deve… | Toxicology reports 2026-08-16 13:14:02 | Source |
| Precise diagnosis of hepatocellular carcinoma and acute kidney injury… Losartan · PMID 42401471 | Hypertension artérielle | Remyélinisation indirecte / réparation · Ralentissement de la progression | Publication | PubMed | Voir la publication source Herein, hepatocellular carcinoma (HCC) and acute kidney injury (AKI) were accomplished using α-l-fucosidase (AFU)-respo… | Analytica chimica acta 2026-08-16 13:14:02 | Source |
| Global, regional, and national burden of breast cancer among females,… Using Healthcare Financing and Digital Technology to Improve Hypertension Prevention and Contr… | Cancer | Ralentissement de la progression | Publication | PubMed | Voir la publication source Breast cancer is a leading cause of mortality and morbidity among females worldwide. As part of the Global Burden of Di… | The Lancet. Oncology 2026-08-16 13:14:01 | Source |
| The global, regional, and national burden of cancer, 1990-2023, with… Using Healthcare Financing and Digital Technology to Improve Hypertension Prevention and Contr… | Cancer | Ralentissement de la progression · Thérapie génique | Publication | PubMed | Voir la publication source Cancer is a leading cause of death globally. Accurate cancer burden information is crucial for policy planning, but man… | Lancet (London, England) 2026-08-16 13:14:01 | Source |
| A novel 14 gauge needle for 2 lead access for percutaneous spinal cor… Permanent Epidural Spinal Cord Stimulation · PMID 41812041 | Hypertension artérielle | Traitement symptomatique | Publication | PubMed | Voir la publication source There are numerous clinical problems with the current 2-needle approach to spinal cord stimulator (SCS) epidural space… | Pain medicine (Malden, Mass.) 2026-08-16 13:14:00 | Source |
| Minimally Invasive Spinal Cord Stimulator Paddle Electrode Placement:… Permanent Epidural Spinal Cord Stimulation · PMID 41090928 | Hypertension artérielle | Traitement symptomatique | Publication | PubMed | Voir la publication source Spinal cord stimulation (SCS) is a widespread tool used to treat chronic pain. There are 2 primary methods for permanen… | Operative neurosurgery (Hagerstown, Md.) 2026-08-16 13:14:00 | Source |
| [Central invasive neuromodulation for the treatment of chronic pain :… Permanent Epidural Spinal Cord Stimulation · PMID 42059911 | Accident vasculaire cérébral | Traitement symptomatique | Publication | PubMed | Voir la publication source Treatment of central neuropathic pain, such as pain after plexus avulsion, stroke or cerebral hemorrhage (central post-… | Schmerz (Berlin, Germany) 2026-08-16 13:14:00 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||