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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Pooled analysis of 2 clinical trials of first-line chemoimmunotherapy… Nivolumab · PMID 42322272 | Cancer | Ralentissement de la progression · Thérapie génique | Publication | PubMed | Voir la publication source Colorectal cancer with microsatellite stable (MSS) status is intrinsically resistant to immune checkpoint inhibitor mon… | Oncoimmunology 2026-08-16 13:17:49 | Source |
| Corrigendum to "Theranostic potential of ramucirumab functionalized m… Ramucirumab · PMID 42551528 | Cancer · Maladie de Parkinson · Maladie de Parkinson | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Journal of pharmaceutical sciences 2026-08-16 13:17:48 | Source |
| Matching-adjusted indirect comparison of fruquintinib versus ramuciru… Ramucirumab · PMID 42583940 | Cancer · Maladie de Parkinson · Maladie de Parkinson | Ralentissement de la progression | Publication | PubMed | Voir la publication source Fruquintinib (Fruq), a selective VEGFR 1/2/3 inhibitor, showed a significant progression-free survival (PFS) benefit in… | Journal of comparative effectiveness research 2026-08-16 13:17:48 | Source |
| Clinical characteristics of ALK-positive NSCLC patients treated with… Lorlatinib · PMID 42505144 | Cancer | Ralentissement de la progression | Publication | PubMed | Voir la publication source Although sequential treatment with ALK-TKIs for ALK-positive lung cancer is commonly practiced in clinical settings, th… | Lung cancer management 2026-08-16 13:17:47 | Source |
| Cost-effectiveness analysis of lorlatinib as first-line treatment for… Lorlatinib · PMID 42043888 | Cancer | Ralentissement de la progression | Publication | PubMed | Voir la publication source Lorlatinib is a third-generation anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitor (TKI) with high central ner… | Journal of medical economics 2026-08-16 13:17:47 | Source |
| Cost of managing brain metastases in patients with ALK+ advanced NSCL… Lorlatinib · PMID 42480036 | Cancer | À vérifier | Publication | PubMed | Voir la publication source This study aimed to estimate the NHS costs of managing patients with anaplastic lymphoma kinase positive (ALK+) advance… | Lung cancer management 2026-08-16 13:17:47 | Source |
| Breakthrough Invasive Fungal Infections in Pediatric Acute Myeloid an… Liposomal Amphotericin B · PMID 41772780 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Breakthrough invasive fungal infections (IFIs) remain a major challenge in children with acute leukemia, even under mol… | The Pediatric infectious disease journal 2026-08-16 13:17:46 | Source |
| In situ assessment of cellular hydrogel swelling behaviors via microb… Microbubbles · PMID 42531650 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Hydrogels exhibit stimuli-responsive swelling behaviors that are beneficial for biomedical applications including disea… | Ultrasonics 2026-08-16 13:17:46 | Source |
| Low-intensity pulsed ultrasound combined with microbubbles enhances a… Microbubbles · PMID 42241274 | Cancer | Immunomodulation | Publication | PubMed | Voir la publication source Cryptococcal meningitis (CM), a life-threatening fungal infection of the central nervous system, faces therapeutic chal… | Drug delivery 2026-08-16 13:17:46 | Source |
| Subharmonics are not an infallible safety metric for cavitation dynam… Microbubbles · PMID 41638992 | Cancer | À vérifier | Publication | PubMed | Voir la publication source There has been a substantial increase in the range of applications for focused ultrasound in recent years with multiple… | International journal of hyperthermia : the official j… 2026-08-16 13:17:46 | Source |
| Successful salvage treatment of and co-infection with oral encochleat… Liposomal Amphotericin B · PMID 42326380 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Antifungal treatment of invasive fungal infections (IFI) in immunocompromised children is challenging. We present a cas… | Medical mycology case reports 2026-08-16 13:17:46 | Source |
| When the test lies: Fatal cryptococcosis and the prozone effect in ad… Liposomal Amphotericin B · PMID 42302495 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Cryptococcal meningitis is a life-threatening opportunistic infection in advanced HIV disease. Cryptococcal antigen (Cr… | Diagnostic microbiology and infectious disease 2026-08-16 13:17:46 | Source |
| Fast lesion mapping during HIFU treatment using harmonic motion imagi… Harmonic motion imaging guided focused ultrasound (HMIgFUS) · PMID 28323638 | Cancer | À vérifier | Publication | PubMed | Voir la publication source The successful clinical application of high intensity focused ultrasound (HIFU) ablation depends on reliable monitoring… | Physics in medicine and biology 2026-08-16 13:17:44 | Source |
| Multi-Amplitude Modulation Frequency in Harmonic Motion Imaging Guide… Harmonic motion imaging guided focused ultrasound (HMIgFUS) · PMID 42024927 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Harmonic Motion Imaging (HMI) is an ultrasound acoustic radiation-force (RF) based elasticity imaging technique, in whi… | IEEE transactions on bio-medical engineering 2026-08-16 13:17:44 | Source |
| E-cigarette or vaping product use-associated lung injury without pulm… Prednisone acetate · PMID 42566571 | Cancer | Traitement symptomatique | Publication | PubMed | Voir la publication source E-cigarette or vaping product use-associated lung injury (EVALI) is a rare pulmonary condition linked to the use of e-c… | Medicine 2026-08-16 13:17:43 | Source |
| Oral AA amyloidosis with granulomatous cheilitis: a case report and l… Prednisone acetate · PMID 41979812 | Cancer | Traitement symptomatique | Publication | PubMed | Voir la publication source We report a rare case of oral AA amyloidosis coexisting with granulomatous cheilitis. A 48-year-old woman presented wit… | Clinical rheumatology 2026-08-16 13:17:43 | Source |
| [Ameliorative effects and mechanisms of Buyang Huanwu Decoction and i… Prednisone acetate · PMID 42543345 | Cancer | Immunomodulation · Thérapie cellulaire · Thérapie génique | Publication | PubMed | Voir la publication source This study aimed to investigate the differences in the ameliorative effects and underlying mechanisms of Buyang Huanwu… | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi =… 2026-08-16 13:17:43 | Source |
| Immune Spatial Organization Predicts Distant Metastasis Risk in Aggre… Abiraterone acetate · PMID 42113020 | Cancer | Immunomodulation | Publication | PubMed | Voir la publication source Computational pathology has emerged as an attractive option for improving risk stratification in prostate cancer, but m… | Clinical cancer research : an official journal of the… 2026-08-16 13:17:42 | Source |
| Metabolic Dysfunction After Initiation of Androgen Receptor Pathway I… Abiraterone acetate · PMID 42593785 | Hypertension artérielle · Cancer | À vérifier | Publication | PubMed | Voir la publication source Metabolic syndrome (MetS) includes obesity, insulin resistance, hypertension, and dyslipidemia. While androgen deprivat… | JAMA oncology 2026-08-16 13:17:42 | Source |
| Targeting the PI3K/AKT pathway in prostate cancer: the role of PTEN d… Abiraterone acetate · PMID 42359636 | Cancer | Ralentissement de la progression | Publication | PubMed | Voir la publication source Loss of the tumor suppressor gene is a common molecular feature in advanced prostate cancer and is associated with acti… | Cancer biology & therapy 2026-08-16 13:17:42 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||