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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Hepatic arterial infusion pump chemotherapy combined with systemic th… Intra arterial infusion Floxuridine (FUDR) combined with systemic therapy · PMID 42143303 | Cancer | Ralentissement de la progression | Publication | PubMed | Voir la publication source In patients with colorectal cancer liver metastases (CRLM), resection of the primary tumour and local treatment of live… | BMC cancer 2026-08-16 13:18:29 | Source |
| Hepatic Arterial Infusion Pump Chemotherapy in Patients With Unresect… Intra arterial infusion Floxuridine (FUDR) combined with systemic therapy · PMID 41082695 | Cancer | À vérifier | Publication | PubMed | Voir la publication source The 3-year overall survival (OS) for advanced intrahepatic cholangiocarcinoma (iCCA) confined to the liver after system… | Journal of clinical oncology : official journal of the… 2026-08-16 13:18:29 | Source |
| Retrospective Analysis of HAIP Therapy in Metastatic Colorectal Cance… Intra arterial infusion Floxuridine (FUDR) combined with systemic therapy · PMID 41563534 | Cancer | Ralentissement de la progression | Publication | PubMed | Voir la publication source PURPOSE: Hepatic arterial infusion pump (HAIP) therapy is a promising treatment for metastatic colorectal cancer (mCRC)… | Journal of gastrointestinal cancer 2026-08-16 13:18:29 | Source |
| Analytical convolution/superposition modelling of one-dimensional dos… Varian Truebeam Radiotherapy System · PMID 42556395 | Cancer | Thérapie génique | Publication | PubMed | Voir la publication source Accurate modelling of dose deposition remains a central challenge in external beam radiotherapy, particularly for moder… | Physics in medicine and biology 2026-08-16 13:18:28 | Source |
| Comparative assessment of kV imaging air kerma for intrafraction pros… Varian Truebeam Radiotherapy System · PMID 42302590 | Cancer | À vérifier | Publication | PubMed | Voir la publication source To compare the accumulated kerma-in-air associated with intrafraction fiducial-based prostate localization in stereotac… | Physica medica : PM : an international journal devoted… 2026-08-16 13:18:28 | Source |
| HyperSight CBCT dose calculation accuracy for adaptive head and neck… Varian Truebeam Radiotherapy System · PMID 42563358 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Head and neck (H&N) patients frequently undergo anatomical changes such as weight loss and tumour shrinkage during trea… | Medical physics 2026-08-16 13:18:28 | Source |
| Comparative efficacy and thyroid function effects of non-surgical tre… Radiofrequency · PMID 42581826 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Non-surgical treatments for benign thyroid nodules (BTN) have shown variable effects across different outcome domains,… | International journal of hyperthermia : the official j… 2026-08-16 13:18:27 | Source |
| Cryoablation versus radiofrequency ablation for hepatocellular carcin… Radiofrequency · PMID 42595456 | Cancer | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source This systematic review and meta-analysis was conducted to comprehensively examine the clinical effectiveness and safety… | International journal of hyperthermia : the official j… 2026-08-16 13:18:27 | Source |
| Endoscopic necrosectomy is safe in patients with pancreatic walled-of… Endorotor · PMID 41567603 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Endoscopic transmural drainage with subsequent endoscopic necrosectomy (EN) has become the first-line treatment for acu… | Endoscopy international open 2026-08-16 13:18:24 | Source |
| Safety, efficacy, and clinical utility of the 5.1-mm debridement cath… Endorotor · PMID 38431104 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Direct endoscopic necrosectomy (DEN) is a recommended strategy for treatment of walled-off necrosis (WON). DEN uses a v… | Gastrointestinal endoscopy 2026-08-16 13:18:24 | Source |
| Scarred and complex colorectal polyps: Traditional techniques and eme… Endorotor · PMID 40900868 | Cancer | Thérapie génique | Publication | PubMed | Voir la publication source Colorectal polyps remain a significant health concern because they can develop into cancer. Therefore, accurate assessm… | World journal of methodology 2026-08-16 13:18:24 | Source |
| Comparative study on the effects of high-intensity focused ultrasound… high-intensity focused ultrasound ablation · PMID 42544600 | Cancer | À vérifier | Publication | PubMed | Voir la publication source To compare the effects of high-intensity focused ultrasound (HIFU) ablation and laparoscopic myomectomy on ovarian func… | International journal of hyperthermia : the official j… 2026-08-16 13:18:20 | Source |
| Noninvasive treatment strategy for abdominal wall desmoid tumors appl… high-intensity focused ultrasound ablation · PMID 42563407 | Cancer | Ralentissement de la progression | Publication | PubMed | Voir la publication source Desmoid tumor (DT) is a rare, locally invasive soft tissue tumor that does not metastasize but has a high recurrence ra… | International journal of hyperthermia : the official j… 2026-08-16 13:18:20 | Source |
| Safety, feasibility, and palliative benefit of HIFU combined with PD-… high-intensity focused ultrasound ablation · PMID 42552867 | Cancer | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Pancreatic cancer remains largely refractory to immune checkpoint inhibitors. High-intensity focused ultrasound (HIFU)… | International journal of hyperthermia : the official j… 2026-08-16 13:18:20 | Source |
| Oncological efficacy, functional outcomes and safety of MR-guided ult… MRI guided transurethral HIFU ablation of prostatic tissue · PMID 42056384 | Cancer | Thérapie génique | Publication | PubMed | Voir la publication source MR-guided focused ultrasound (MRgFUS) and transurethral ultrasound ablation (TULSA) have emerged as MRI-guided, minimal… | La Radiologia medica 2026-08-16 13:18:19 | Source |
| Absorbed dose evaluation of Auger electron-emitting radionuclides: im… I-124 · PMID 28102829 | Cancer | Thérapie génique | Publication | PubMed | Voir la publication source The aim of this study was to investigate the impact of decay data provided by the newly developed stochastic atomic rel… | Physics in medicine and biology 2026-08-16 13:18:17 | Source |
| ACR Appropriateness Criteria® Staging and Follow-Up of Adrenal Cancer. I-131 · PMID 41863523 | Cancer | Thérapie génique | Publication | PubMed | Voir la publication source Primary adrenal gland malignancies include adrenocortical carcinoma (ACC) and pheochromocytoma. For initial staging and… | Journal of the American College of Radiology : JACR 2026-08-16 13:18:17 | Source |
| Development of Antibody and Antibody Fragment-Based Radiopharmaceutic… I-124 · PMID 42273652 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Cancer has been the leading cause of death and imposing tremendous socioeconomical pressure worldwide. It is considered… | Nuclear medicine and molecular imaging 2026-08-16 13:18:17 | Source |
| Predictive factors for therapeutic response to radioactive iodine the… I-131 · PMID 42274916 | Cancer | À vérifier | Publication | PubMed | Voir la publication source To evaluate the therapeutic outcomes of radioactive iodine (RAI) therapy for pulmonary metastases from differentiated t… | Japanese journal of radiology 2026-08-16 13:18:17 | Source |
| Clinical impact of a single time-point protocol paired FDG-PET and ra… Thyrogen · PMID 42322900 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Treatment decisions in advanced or metastatic differentiated thyroid cancer require comprehensive clinical, genomic, an… | Current problems in cancer 2026-08-16 13:18:16 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||