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Périmètre
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Chaque choix s’applique immédiatement aux quatre sections. Le filtre « type de SEP » n’apparaît que lorsque la sclérose en plaques est sélectionnée.
10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| A stronger type I interferon signature distinguishes ANCA-associated… Urinary T Cell Biomarker for Prediction in Lupus Nephritis · PMID 40935134 | Lupus | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) causes severe multisystemic organ damage. The m… | Kidney international 2026-08-16 13:21:38 | Source |
| Factors Associated with Glucocorticoid Withdrawal in Systemic Lupus E… Belimumab · PMID 42593757 | Lupus | À vérifier | Publication | PubMed | Voir la publication source To examine the rate of glucocorticoid (GC) discontinuation and to identify factors associated with successful GC withdr… | Modern rheumatology 2026-08-16 13:21:36 | Source |
| Pediatric Systemic Lupus Erythematosus Complicated by Acute EBV and C… Belimumab · PMID 42596845 | Lupus | Immunomodulation | Publication | PubMed | Voir la publication source Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disease characterized by multi-organ damage, with gen… | Journal of clinical laboratory analysis 2026-08-16 13:21:36 | Source |
| Anti-SARS-CoV-2 response in alveolar blood sample and bronchoalveolar… Blood sample · PMID 42081587 | Lupus · Myopathies · Sclérose en plaques · Lupus · Sclérose en plaque… | À vérifier | Publication | PubMed | Voir la publication source Mucosal antibody response in lower respiratory tract to COVID-19 vaccines is less studied. This cross-sectional study e… | Human vaccines & immunotherapeutics 2026-08-16 13:21:34 | Source |
| Association between PFAS and renal function indicators in cord blood… Blood sample · PMID 42222903 | Lupus · Myopathies · Sclérose en plaques · Lupus · Sclérose en plaque… | Thérapie génique | Publication | PubMed | Voir la publication source Evidence on the associations between per- and polyfluoroalkyl substances (PFAS) exposure and renal function in newborns… | Annals of medicine 2026-08-16 13:21:34 | Source |
| High-performance surface plasmon resonance biosensor design: Encircle… Blood sample · PMID 42442310 | Lupus · Myopathies · Sclérose en plaques · Lupus · Sclérose en plaque… | À vérifier | Publication | PubMed | Voir la publication source In the last few years, chemical analysis and chromatography approaches have been implemented widely for detecting marij… | Spectrochimica acta. Part A, Molecular and biomolecula… 2026-08-16 13:21:34 | Source |
| Cytokine release syndrome mimicking drug reaction with eosinophilia a… Blinatumomab · PMID 42569543 | Cancer · Lupus · Myasthénie · Sclérose en plaques · Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | JAAD case reports 2026-08-16 13:21:32 | Source |
| Derivation of an occupational exposure limit (OEL) for a potent bispe… Blinatumomab · PMID 42162781 | Cancer · Lupus · Myasthénie · Sclérose en plaques · Myasthénie | À vérifier | Publication | PubMed | Voir la publication source As part of product stewardship, pharmaceutical companies generate and evaluate nonclinical and clinical data to establi… | Regulatory toxicology and pharmacology : RTP 2026-08-16 13:21:32 | Source |
| Ibuprofen vs. acetaminophen for acute mild-to-moderate pain managemen… Acetaminophen/Paracetamol · PMID 42448615 | Lupus · Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source The purpose of this study is to compare the safety of ibuprofen and acetaminophen (paracetamol) for acute mild-to-moder… | British journal of clinical pharmacology 2026-08-16 13:21:32 | Source |
| Optimizing safety and efficacy of asparaginase and blinatumomab thera… Blinatumomab · PMID 42578884 | Cancer · Lupus · Myasthénie · Sclérose en plaques · Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Frontline blinatumomab combined with chemotherapy has resulted in improved outcomes in both pediatric and adult patient… | Cancer 2026-08-16 13:21:32 | Source |
| Safety of acetylcysteine: a scoping review of iatrogenic overdose cas… Acetaminophen/Paracetamol · PMID 42370551 | Lupus · Migraine | Ralentissement de la progression | Publication | PubMed | Voir la publication source Acetylcysteine is the standard antidote for acetaminophen (paracetamol) toxicity and is widely considered safe when adm… | Clinical toxicology (Philadelphia, Pa.) 2026-08-16 13:21:32 | Source |
| Generating multiple-choice questions using reverse engineering techni… Educational materials · PMID 41510996 | Lupus | À vérifier | Publication | PubMed | Voir la publication source The study is aimed at exploring the potential of using ChatGPT-4 to develop multiple-choice questions that adhere to it… | Medical education online 2026-08-16 13:21:29 | Source |
| Informing food safety trainings in low- and middle-income countries:… Educational materials · PMID 42464670 | Lupus | À vérifier | Publication | PubMed | Voir la publication source Over the past two decades, food safety training interventions in LMICs have increased significantly, yet improvements i… | Global health action 2026-08-16 13:21:29 | Source |
| Qualitative analysis of out-of-hospital self-management capabilities… Educational materials · PMID 41689385 | Lupus | Traitement symptomatique | Publication | PubMed | Voir la publication source Postoperative patients with gynecological malignant tumors are prone to venous thromboembolism (VTE) due to hypercoagul… | Annals of medicine 2026-08-16 13:21:29 | Source |
| A Culturally Tailored Educational Program for Breast Cancer Risk Redu… Tailored educational program · PMID 41742629 | Cancer | À vérifier | Publication | PubMed | Voir la publication source This study evaluated the effectiveness of a culturally tailored educational program, the Korean Breast Cancer Risk Redu… | Public health nursing (Boston, Mass.) 2026-08-16 13:21:28 | Source |
| BRIDGE implementation science study to improve chronic spontaneous ur… Tailored educational program · PMID 41732687 | Lupus | À vérifier | Publication | PubMed | Voir la publication source Delay in diagnosis and referral to a specialist negatively affects the quality of life of patients with uncontrolled ch… | The journal of allergy and clinical immunology. Global 2026-08-16 13:21:28 | Source |
| Comparative effectiveness and predictors of SRI-4 and LLDAS attainmen… Telitacicept · PMID 42601521 | Lupus | À vérifier | Publication | PubMed | Voir la publication source To compare the attainment of Systemic Lupus Erythematosus Responder Index 4 (SRI-4) and lupus low disease activity stat… | Clinical rheumatology 2026-08-16 13:21:27 | Source |
| Effect of oral calcium carbonate on uterine contractility: a pilot ra… standard therapy · PMID 42480078 | Lupus | À vérifier | Publication | PubMed | Voir la publication source Ineffective uterine contractions contribute to labour dystocia and are a leading indication for primary caesarean deliv… | Journal of obstetrics and gynaecology : the journal of… 2026-08-16 13:21:27 | Source |
| Research on the safety and efficacy of telitacicept in the treatment… Telitacicept · PMID 42290288 | Lupus · Myasthénie · Lupus · Myasthénie | À vérifier | Publication | PubMed | Voir la publication source This study retrospectively evaluated telitacicept in ten pediatric IgA nephropathy patients with proteinuria (24-hour u… | Renal failure 2026-08-16 13:21:27 | Source |
| The effects of asymmetrical versus symmetrical high-flow nasal cannul… standard therapy · PMID 42345563 | Lupus | Thérapie génique | Publication | PubMed | Voir la publication source High-flow nasal cannula (HFNC) is standard therapy for acute hypoxaemic respiratory failure and is increasingly used in… | Pulmonology 2026-08-16 13:21:27 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||