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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Protocol for simultaneous non-invasive electrocardiogram and respirat… Kinesiology tape · PMID 42455681 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Here, we present a protocol for non-invasive simultaneous recording of electrocardiogram (ECG) and breathing in conscio… | STAR protocols 2026-08-16 13:25:08 | Source |
| Prospective Study of Video Hand Opening Time as a Quantitative Measur… SOUL-DM1 — Symptoms and Outcome Measures for Upper- Limb Function in Myotonic Dystrophy Type 1… | Myopathies | Ralentissement de la progression · Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Delayed grip relaxation is a common symptom of myotonic dystrophy type 1 (DM1), differing from other muscle diseases. P… | Neurology 2026-08-16 13:25:04 | Source |
| Case Report: Overlap of long QT syndrome and catecholaminergic polymo… Mexiletine · PMID 42558477 | Myopathies · Sclérose latérale amyotrophique · Sclérose latérale amyo… | À vérifier | Publication | PubMed | Voir la publication source Calmodulinopathy is a rare -related hereditary channelopathy presenting with long QT syndrome (LQTS), less commonly wit… | Frontiers in pediatrics 2026-08-16 13:25:02 | Source |
| HIF-Prolyl Hydroxylase Inhibitor Desidustat Increases Pyruvate Kinase… GSK1278863 · PMID 40192567 | Myopathies | Neuroprotection · Traitement symptomatique | Publication | PubMed | Voir la publication source Sickle cell anemia and beta-thalassemia are the major hemoglobinopathies associated with anemia. Bone marrow transplant… | Drug development research 2026-08-16 13:24:56 | Source |
| An investigation of a novel public health campaign to improve underst… Pain Science Education · PMID 42176372 | Myopathies | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Persistent pain is a high priority global public health issue. Misconceptions about persistent pain prevail in society… | Musculoskeletal science & practice 2026-08-16 13:24:52 | Source |
| Complex intervention including pain science education and patient-led… Pain Science Education · PMID 39739224 | Cancer | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Up to 74% of breast cancer survivors (BCS) treated with aromatase inhibitor (AI) experience AI-induced musculoskeletal… | Journal of cancer survivorship : research and practice 2026-08-16 13:24:52 | Source |
| Diffusion-weighted magnetic resonance imaging as a promising techniqu… Magnetic Resonance Imaging and Ultrasound Comparison With Load Evaluation · PMID 42599582 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source A combination of morphological and functional imaging plays a crucial role for neuroendocrine tumors (NETs) management.… | Journal of endocrinological investigation 2026-08-16 13:24:52 | Source |
| Quantitative susceptibility mapping of the brain is associated with i… Magnetic Resonance Imaging and Ultrasound Comparison With Load Evaluation · PMID 41656561 | Maladie d’Alzheimer | Immunomodulation | Publication | PubMed | Voir la publication source Accumulation of paramagnetic substances in brain tissue may constitute a feature of Alzheimer's disease (AD) associated… | Journal of cerebral blood flow and metabolism : offici… 2026-08-16 13:24:52 | Source |
| A Step-Up Underwater Endoscopic Mucosal Resection Strategy with Rescu… GenPHSat injection (Safety) · PMID 42111926 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Underwater endoscopic mucosal resection (UEMR) is an established treatment for non-pedunculated colorectal lesions, but… | DEN open 2026-08-16 13:24:48 | Source |
| Efficiency and Safety of Endoscopic Injection Sclerotherapy With Liga… GenPHSat injection (Safety) · PMID 42088735 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Endoscopic injection sclerotherapy with ligation (EISL) is a combined endoscopic treatment that involves endoscopic inj… | DEN open 2026-08-16 13:24:48 | Source |
| Real-time NMR analysis of glutamine metabolism for screening anti-can… Glutamine · PMID 42518517 | Cancer | Ralentissement de la progression | Publication | PubMed | Voir la publication source Metabolic reprogramming is a substantial obstacle for anticancer drug screening, as targeted therapeutics often lose ef… | Magnetic resonance letters 2026-08-16 13:24:46 | Source |
| Transglutaminase 2 regulates innate immunity: mechanisms and therapeu… Glutamine · PMID 42053427 | Myopathies | Immunomodulation | Publication | PubMed | Voir la publication source Innate immunity constitutes the primary barrier against invading pathogens and plays a crucial role in coordinating the… | Oncoimmunology 2026-08-16 13:24:46 | Source |
| Creatine monohydrate for lean mass, strength, and bone density in pos… Creatine Monohydrate · PMID 42141930 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Menopause is accompanied by accelerated losses in muscle mass and strength and declining bone density. Whether creatine… | Journal of the International Society of Sports Nutriti… 2026-08-16 13:24:45 | Source |
| The emerging and evolving evidence supporting creatine as an ergogeni… Creatine Monohydrate · PMID 41870601 | Myopathies | Neuroprotection · Immunomodulation | Publication | PubMed | Voir la publication source Creatine is one of the most extensively studied ergogenic aids, with over three decades of research supporting its role… | Journal of the International Society of Sports Nutriti… 2026-08-16 13:24:45 | Source |
| Beyond rodents: A systematic review of antidepressant-like effects in… Desipramine · PMID 42538543 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source The development of antidepressants has traditionally relied on vertebrate models. offers a promising alternative approa… | Alternatives to laboratory animals : ATLA 2026-08-16 13:24:34 | Source |
| A Real-World Target Trial Emulation of Eteplirsen, Casimersen, and Go… Casimersen · PMID 42250075 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Real-world data are needed to understand the treatment effect of eteplirsen, casimersen, and golodirsen (phosphorodiami… | Advances in therapy 2026-08-16 13:24:30 | Source |
| Anti-GAD65 antibody-associated cerebellar ataxia in a young adult wit… IvIg · PMID 42582350 | Myopathies · Sclérose en plaques · Myopathies | À vérifier | Publication | PubMed | Voir la publication source Anti-glutamic acid decarboxylase antibody-associated cerebellar ataxia (anti-GAD-CA) is a rare autoimmune neurological… | Diabetology international 2026-08-16 13:24:24 | Source |
| SARS-CoV-2-induced IgG repertoires shape T cell responses, microRNA r… IvIg · PMID 42604002 | Myopathies · Sclérose en plaques · Myopathies | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source SARS-CoV-2 infection can generate IgG repertoires with functions beyond viral neutralization. We purified IgG from non-… | Journal of translational autoimmunity 2026-08-16 13:24:24 | Source |
| The economic value of self-administered subcutaneous immunoglobulin G… IvIg · PMID 41701183 | Myopathies · Sclérose en plaques · Myopathies | À vérifier | Publication | PubMed | Voir la publication source Subcutaneous immunoglobulin (SCIg) is a treatment available in Canada for patients requiring antibody replacement. Whil… | Journal of medical economics 2026-08-16 13:24:24 | Source |
| Antigen-specific IgY as an orally deliverable biomaterial for sustain… Behavioral Interventions for Controlling Oral Behaviors · PMID 42140132 | Myopathies | Immunomodulation | Publication | PubMed | Voir la publication source Over the past decades, antibodies have become indispensable tools due to their high specificity and versatility. Egg yo… | Colloids and surfaces. B, Biointerfaces 2026-08-16 13:24:23 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||