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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Population histamine burden assessed using wastewater-based epidemiol… Fexofenadine, Ranitidine · PMID 30096611 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Systematic sampling and analysis of wastewater has become an important tool for monitoring consumption of drugs and oth… | Environment international 2026-11-01 04:36:50 | Source |
| Accessing and Navigating Gender-Affirming Hormone Therapy and Perspec… gender-affirming hormone therapy · PMID 42949784 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Transgender and gender diverse (TGD) people continue to experience inequities in access to gender-affirming care, inclu… | Health expectations : an international journal of publ… 2026-11-01 04:36:46 | Source |
| Changes in Hormone Cycles and Exercise Capacity During Testosterone T… gender-affirming hormone therapy · PMID 42871731 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The impact of testosterone therapy on the hormone cycles, exercise capacity, and physiology of transmasculine individua… | Exercise, sport & movement 2026-11-01 04:36:46 | Source |
| Efficacy of Electroacupuncture for Chronic Pelvic Pain: A Randomized,… Sham electroacupuncture · PMID 42835730 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source To evaluate the efficacy and safety of electroacupuncture in the management of chronic pelvic pain (CPP). This randomiz… | Journal of pain research 2026-11-01 04:36:46 | Source |
| Electroacupuncture Ameliorating Cerebral I/R-Induced Inflammatory Res… Sham electroacupuncture · PMID 42888320 | Accident vasculaire cérébral | Neuroprotection · Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source The inflammatory response plays a crucial role in cerebral ischemia/reperfusion (I/R) injury and may offer a new therap… | Neurocritical care 2026-11-01 04:36:46 | Source |
| Electroacupuncture modulates cortical functional connectivity and net… Sham electroacupuncture · PMID 42824526 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Acupuncture has shown clinical benefits in post-stroke rehabilitation, yet its central neural mechanisms remain incompl… | Cognitive neurodynamics 2026-11-01 04:36:46 | Source |
| Progesterone in feminizing gender affirming hormone therapy: study pr… gender-affirming hormone therapy · PMID 42764919 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Transgender women receiving feminizing hormone therapy increasingly request progesterone based on anecdotal reports of… | Contemporary clinical trials communications 2026-11-01 04:36:46 | Source |
| Documented follow-up to memory concerns reported at the Medicare Annu… Adults with Alzheimer's disease · PMID 42243620 | Maladie d’Alzheimer | À vérifier | Publication | PubMed | Voir la publication source The Medicare Annual Wellness Visit (AWV) may improve timely detection of Alzheimer's disease and related dementias (ADR… | Alzheimer's & dementia : the journal of the Alzheimer'… 2026-11-01 04:36:31 | Source |
| Astrocytic synapse engulfment is differentially controlled by APOE ge… APOE genotype · PMID 42759807 | Maladie d’Alzheimer | À vérifier | Publication | PubMed | Voir la publication source APOE gene variants encoding the apolipoprotein E (ApoE) protein are strong genetic modifiers of risk of Alzheimer's dis… | Neuroscience 2026-11-01 04:36:27 | Source |
| Older adult APOE4 mice exhibit modest immunometabolic adaptation foll… APOE genotype · PMID 42748650 | Maladie d’Alzheimer | Immunomodulation | Publication | PubMed | Voir la publication source Apolipoprotein E (APOE) genotype is the strongest genetic determinant of late-onset Alzheimer's disease (AD) risk. Of i… | Neurobiology of aging 2026-11-01 04:36:27 | Source |
| Sex and APOE genotype specific brain regional vulnerability to Alzhei… APOE genotype · PMID 41708549 | Maladie d’Alzheimer | Ralentissement de la progression | Publication | PubMed | Voir la publication source Alzheimer's disease (AD) disproportionately affects women and carriers of the apolipoprotein E ε4 allele (APOE4), yet l… | GeroScience 2026-11-01 04:36:27 | Source |
| A comparison of therapeutic oxygen versus medical air for the treatme… Polysomnogram · PMID 42287973 | Maladie d’Alzheimer · Maladie de Parkinson | À vérifier | Publication | PubMed | Voir la publication source Central sleep apnea (CSA) is common in infants with Prader-Willi syndrome (PWS). Although supplemental oxygen is freque… | Sleep medicine 2026-11-01 04:36:26 | Source |
| International Survey of Growth Hormone and Sleep Evaluation Practices… Polysomnogram · PMID 42830614 | Maladie d’Alzheimer · Maladie de Parkinson | Thérapie génique | Publication | PubMed | Voir la publication source Guidelines encourage polysomnogram (PSG) prior to starting growth hormone (GH) in individuals with Prader-Willi Syndrom… | Clinical endocrinology 2026-11-01 04:36:26 | Source |
| Preceding night sleep time and multiple sleep latency test outcomes. Polysomnogram · PMID 42821195 | Maladie d’Alzheimer · Maladie de Parkinson | À vérifier | Publication | PubMed | Voir la publication source Evidence supporting how much sleep the night before a multiple sleep latency test (MSLT) is required to generate valid… | Sleep & breathing = Schlaf & Atmung 2026-11-01 04:36:26 | Source |
| One-stop photon-counting CT angiography for simultaneous assessment o… CT Scan · PMID 42960276 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source We report a 73-year-old male admitted for 2-year progressive dysuria, with incidental detection of abnormal cardiovascu… | Radiology case reports 2026-11-01 04:36:19 | Source |
| Potential to improve early detection of lung cancer through expansion… CT Scan · PMID 42864862 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Low-dose computerized tomography (LDCT) is the gold standard for lung cancer (LC) screening, but access is hindered by… | Lung cancer management 2026-11-01 04:36:19 | Source |
| Study protocol for the TROG 21.08 VITaL trial: a randomized controlle… CT Scan · PMID 42910049 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Radiation therapy (RT) is indicated for 77% of patients with lung cancer. Over 20% of patients are affected by radiatio… | Clinical and translational radiation oncology 2026-11-01 04:36:19 | Source |
| Aliskiren: a review of its use as monotherapy and as combination ther… Ramipril tablet · PMID 20883056 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Aliskiren is an orally administered, nonpeptide direct renin inhibitor indicated for the management of hypertension. Al… | Drugs 2026-10-25 04:37:34 | Source |
| Sexual function among controlled and uncontrolled hypertensive female… Ramipril tablet · PMID 41844720 | Hypertension artérielle | Traitement symptomatique | Publication | PubMed | Voir la publication source Female sexual dysfunction (FSD) among females with hypertension (HTN) is frequently overlooked, with a reported prevale… | Scientific reports 2026-10-25 04:37:34 | Source |
| A mechanism investigation on the effective strategy for alleviating a… Amlodipine tablet · PMID 42629421 | Maladie coronarienne | Neuroprotection · Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Acute myocardial infarction (AMI) and insomnia are mutually causal. However, therapeutic strategies for AMI combined wi… | Naunyn-Schmiedeberg's archives of pharmacology 2026-10-25 04:37:31 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||