Vue transversale globale
Toutes les maladies
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
Filtrer toute la vue
Chaque choix s’applique immédiatement aux quatre sections. Le filtre « type de SEP » n’apparaît que lorsque la sclérose en plaques est sélectionnée.
10635 résultats correspondants
· 41 visibles sur cette page
dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Antiparasitic agents in oncology: Innovative mechanisms, emerging evi… ivermectin · PMID 42217373 | Cancer | Immunomodulation · Thérapie cellulaire | Publication | PubMed | Voir la publication source The repurpose of established antiparasitic agents for oncological applications represents a promising and cost-effectiv… | European journal of medicinal chemistry 2026-08-16 18:24:13 | Source |
| Simple and efficient HPLC-MS/MS method for simultaneous extraction an… ivermectin · PMID 42491371 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Anthelmintic treatment is a common practice in horses. The presence of pharmaceutical residues in fields and pastures i… | MethodsX 2026-08-16 18:24:13 | Source |
| Treatment of redness in rosacea with potassium-titanyl-phosphate (KTP… ivermectin · PMID 41778357 | Épilepsie | Immunomodulation | Publication | PubMed | Voir la publication source Facial erythema and telangiectasia in rosacea are commonly treated with vascular lasers. Combination with ivermectin 1%… | The Journal of dermatological treatment 2026-08-16 18:24:13 | Source |
| Cost-effectiveness analysis of sedation regimens for children undergo… IV midazolam · PMID 40643615 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source This simulation-based cost-effectiveness analysis evaluates various sedation regimens for pediatric magnetic resonance… | Journal of anesthesia 2026-08-16 18:24:12 | Source |
| Bioproducts from Seeds: The Brazilian Caatinga Passion Fruit. Botanical extract from Passiflora incarnata · PMID 37444263 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source The present work aimed to obtain bioproducts from seeds, the Brazilian Caatinga passion fruit, as well as to determine… | Foods (Basel, Switzerland) 2026-08-16 18:24:11 | Source |
| Deep brain stimulation of the thalamus for intractable epilepsy (FRAN… ANT recording and stimulation · PMID 41902639 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source This study was undertaken to evaluate the efficacy and safety of deep brain stimulation (DBS) of the anterior nucleus o… | Epilepsia 2026-08-16 18:24:06 | Source |
| Patient perspectives on hemolytic disease of the fetus and newborn an… Intravenous immunoglobulin · PMID 42580888 | Épilepsie | Thérapie génique | Publication | PubMed | Voir la publication source Hemolytic disease of the fetus and newborn (HDFN) and fetal and neonatal alloimmune thrombocytopenia (FNAIT) are two ra… | The journal of maternal-fetal & neonatal medicine : th… 2026-08-16 18:24:06 | Source |
| Working memory load attenuates the match effect in sentence-picture v… Flexible Representation of Speech · PMID 41975163 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Embodied views of language comprehension argue that the body's perceptual and motor systems ground linguistic meaning.… | Memory & cognition 2026-08-16 18:24:05 | Source |
| Personalized topology-informed localization of standard 12-lead ECG e… Standard electrodes · PMID 39854816 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Cardiac digital twins (CDTs) offer personalized in-silico cardiac representations for the inference of multi-scale prop… | Medical image analysis 2026-08-16 18:24:04 | Source |
| Diagnostic performance comparison of multiplex PCR-based BioFire® joi… retrospective analysis of a panel result · PMID 42349096 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Septic arthritis (SA) is a destructive disease requiring urgent diagnosis and treatment. The low sensitivity of convent… | Diagnostic microbiology and infectious disease 2026-08-16 18:24:02 | Source |
| Prevalence and genotypic distribution of human papillomavirus in Indi… retrospective analysis of a panel result · PMID 42287832 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source While several regional and multicenter studies have documented HPV distribution in India, nationally representative lar… | Diagnostic microbiology and infectious disease 2026-08-16 18:24:02 | Source |
| Unbiased metabolomics screening for potential biomarkers in patients… retrospective analysis of a panel result · PMID 41504866 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source This study utilizes untargeted metabolomics to identify novel serum biomarkers and metabolic pathways linked to in-sten… | Scandinavian cardiovascular journal : SCJ 2026-08-16 18:24:02 | Source |
| Clinical drug-oriented design, synthesis, and pharmacological evaluat… Lacosamide · PMID 42385394 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Epilepsy is a common neurological disorder frequently complicated by drug resistance, underscoring the urgent need for… | Bioorganic chemistry 2026-08-16 18:23:57 | Source |
| Hemodynamic and thermal responses to head and neck cooling in men and… Head and Neck Cooling System · PMID 8985108 | Sclérose en plaques | Traitement symptomatique | Publication | PubMed | Voir la publication source Personal cooling systems are used to alleviate symptoms of multiple sclerosis and to prevent increased core temperature… | American journal of physical medicine & rehabilitation 2026-08-16 18:23:57 | Source |
| Physiologic and thermal responses of male and female patients with mu… Head and Neck Cooling System · PMID 10493455 | Sclérose en plaques | Traitement symptomatique | Publication | PubMed | Voir la publication source Personal cooling systems are used to alleviate symptoms of multiple sclerosis and to prevent increased core temperature… | American journal of physical medicine & rehabilitation 2026-08-16 18:23:57 | Source |
| Bed nucleus of the stria terminalis-nucleus accumbens stimulation for… fMRI of Active DBS Stimulation in Epilepsy · PMID 41923626 | Épilepsie | Ralentissement de la progression | Publication | PubMed | Voir la publication source Although deep brain stimulation (DBS) shows potential in treatment-resistant depression (TRD), the efficacy remains con… | Cell reports. Medicine 2026-08-16 18:23:55 | Source |
| Detection of cardiac pathologies in electrocardiogram signals using e… ECG Vector Determination · PMID 42491352 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source The purpose of this work is to develop an Artificial Intelligence-based system capable of classifying individuals as ei… | Health information science and systems 2026-08-16 18:23:51 | Source |
| Successful Epicardial Ablation of a Right Infero-paraseptal Accessory… ECG Vector Determination · PMID 42580788 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source A 22-year-old man presented with aborted sudden cardiac arrest due to ventricular fibrillation and recurrent tachyarrhy… | Cardiac electrophysiology clinics 2026-08-16 18:23:51 | Source |
| Antidepressant-like effects of valproic acid in rodents go back to th… Levetiracetam &/or sodium valproate · PMID 42530025 | Épilepsie | Traitement symptomatique | Publication | PubMed | Voir la publication source In a recent review and meta-analysis, Goudarzi et al. (Stress, 2026 Dec 31; 29(1):2641561) show that valproic acid (VPA… | Stress (Amsterdam, Netherlands) 2026-08-16 18:23:49 | Source |
| Macrophage metabolic reprogramming via HIF-1α-glycolysis drives osteo… Levetiracetam &/or sodium valproate · PMID 42071169 | Épilepsie | Immunomodulation | Publication | PubMed | Voir la publication source Postmenopausal osteoporosis (PMOP) is characterized by exacerbated bone resorption and inadequate bone formation, with… | Redox report : communications in free radical research 2026-08-16 18:23:49 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||