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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Preoperative 11 C-Methionine PET-MRI in Pediatric Infratentorial Tumo… PET/MRI acquisition · PMID 38498623 | Épilepsie | Traitement symptomatique | Publication | PubMed | Voir la publication source MRI is the main imaging modality for pediatric brain tumors, but amino acid PET can provide additional information. Sim… | Clinical nuclear medicine 2026-08-16 18:24:49 | Source |
| Sequential and Hybrid PET/MRI Acquisition in Follow-Up Examination of… PET/MRI acquisition · PMID 36612079 | Épilepsie | Ralentissement de la progression | Publication | PubMed | Voir la publication source Both positron emission tomography (PET) and magnetic resonance imaging (MRI), including dynamic susceptibility contrast… | Cancers 2026-08-16 18:24:49 | Source |
| Test-retest reproducibility of structural and proxy estimates of brai… PET/MRI acquisition · PMID 41284011 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source While structural connectivity (SC) reflects actual neural connections, proxy estimates of brain connectivity such as fu… | NeuroImage 2026-08-16 18:24:49 | Source |
| Catecholaminergic neurons projecting to the paraventricular nucleus o… 1 Hypercapnic challenge while participant is awake · PMID 26157062 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Brainstem catecholamine neurons modulate sensory information and participate in control of cardiorespiratory function.… | American journal of physiology. Regulatory, integrativ… 2026-08-16 18:24:48 | Source |
| Upper airway resistance during progressive hypercapnia and progressiv… 1 Hypercapnic challenge while participant is awake · PMID 11084201 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Ventilatory motor output is known to influence the upper airway. Although inspiratory upper airway resistance decreases… | Respiration physiology 2026-08-16 18:24:48 | Source |
| Delayed Surgical Evaluation After Drug-Resistant Epilepsy Diagnosis W… Surgery as a Treatment for Medically Intractable Epilepsy · PMID 42479984 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Despite its proven effectiveness, epilepsy surgery for drug-resistant epilepsy (DRE) remains underutilized and frequent… | Neurology. Clinical practice 2026-08-16 18:24:46 | Source |
| Dose-response association between perinatal 25(OH)D status and postpa… S230815- Dose D · PMID 42600057 | Épilepsie | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Postpartum depression (PPD) is a common perinatal disorder that affects maternal and child health. Although vitamin D d… | Journal of psychosomatic obstetrics and gynaecology 2026-08-16 18:24:46 | Source |
| Long-term seizure outcomes in patients with drug-resistant mesial tem… Surgery as a Treatment for Medically Intractable Epilepsy · PMID 42546600 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Resective surgery is a significant therapeutic option for patients with drug-resistant mesial temporal lobe epilepsy (M… | Clinical neurology and neurosurgery 2026-08-16 18:24:46 | Source |
| Trehalose: a potent enhancer of antioxidant responses in L. under ars… S230815- Dose D · PMID 42490066 | Épilepsie | Neuroprotection | Publication | PubMed | Voir la publication source Arsenic contamination poses a major threat to crop productivity by impairing the photosynthetic machinery and inducing… | Plant signaling & behavior 2026-08-16 18:24:46 | Source |
| Adaptive stepped care in preschool-age children with ADHD symptoms: a… S230815- Dose C · PMID 42149230 | Épilepsie | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Parent training and assisted self-help have proven effective in preschool-age children with attention-deficit/hyperacti… | European child & adolescent psychiatry 2026-08-16 18:24:43 | Source |
| Efficacy of a stepped-care approach for school-age children with mild… S230815- Dose C · PMID 42571030 | Épilepsie | Traitement symptomatique | Publication | PubMed | Voir la publication source This German multicenter study aimed to analyze the efficacy of telephone-assisted self-help (TASH) and changes during s… | Child and adolescent psychiatry and mental health 2026-08-16 18:24:43 | Source |
| Efficacy of guided and unguided web-assisted self-help for parents of… S230815- Dose C · PMID 40062662 | Épilepsie | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Empirical evidence supports the efficacy of behavioral online parent training. However, further large trials in school-… | Journal of child psychology and psychiatry, and allied… 2026-08-16 18:24:43 | Source |
| Analysis of Rhizonin Biosynthesis Reveals Origin of Pharmacophoric Fu… S230815- Dose B · PMID 37650335 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Rhizonin A and B are hepatotoxic cyclopeptides produced by bacterial endosymbionts (Mycetohabitans endofungorum) of the… | Angewandte Chemie (International ed. in English) 2026-08-16 18:24:42 | Source |
| Bacterial Isothiocyanate Biosynthesis by Rhodanese-Catalyzed Sulfur T… S230815- Dose B · PMID 37917130 | Épilepsie | Thérapie génique | Publication | PubMed | Voir la publication source Natural products bearing isothiocyanate (ITC) groups are an important group of specialized metabolites that play variou… | Chembiochem : a European journal of chemical biology 2026-08-16 18:24:42 | Source |
| TimeTeller for timing health: The potential of circadian medicine to… S230815- Dose B · PMID 37153516 | Cancer | Thérapie génique | Publication | PubMed | Voir la publication source Circadian medicine, the study of the effects of time on health and disease has seen an uprising in recent years as a me… | Frontiers in digital health 2026-08-16 18:24:42 | Source |
| Randomized trial of dietician counseling to try to prevent weight gai… S230815- Starting dose A · PMID 8643226 | Cancer | À vérifier | Publication | PubMed | Voir la publication source This study was developed to test whether prospective dietician counseling could abrogate the unwanted weight gain seen… | Oncology 2026-08-16 18:24:39 | Source |
| Environmental tobacco smoke exposure and pelvic inflammatory disease:… Metabolites in Blood and Breath in Metabolic Conditions · PMID 41562602 | Épilepsie | Immunomodulation | Publication | PubMed | Voir la publication source Pelvic inflammatory disease (PID) is a common gynaecologic condition linked to infertility, ectopic pregnancy, and repr… | Journal of obstetrics and gynaecology : the journal of… 2026-08-16 18:24:38 | Source |
| Exercise Resistance in Obese Male NZO Mice Manifests as Local Muscle… Metabolites in Blood and Breath in Metabolic Conditions · PMID 42410330 | Épilepsie | Remyélinisation indirecte / réparation | Publication | PubMed | Voir la publication source Exercise improves glycaemic control, yet some individuals show limited benefit, termed exercise resistance. We investig… | Diabetes, obesity & metabolism 2026-08-16 18:24:38 | Source |
| Pre-analytical standardization and multi-biofluid harmonization for l… Metabolites in Blood and Breath in Metabolic Conditions · PMID 42162904 | Cancer | Thérapie génique | Publication | PubMed | Voir la publication source Lung cancer remains the leading cause of cancer-related mortality worldwide, with early detection being critical for im… | Clinica chimica acta; international journal of clinica… 2026-08-16 18:24:38 | Source |
| Bexicaserin for the treatment of seizures in developmental and epilep… LP352 · PMID 41133912 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source This randomized, double-blind, phase 1b/2a clinical trial was designed to evaluate the safety, tolerability, and effica… | Epilepsia 2026-08-16 18:24:37 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||