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Périmètre

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Chaque choix s’applique immédiatement aux quatre sections. Le filtre « type de SEP » n’apparaît que lorsque la sclérose en plaques est sélectionnée.

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Essais et traitements5743Données cliniques et programmes
Recherches et trouvailles21Pipeline scientifique
Publications4871Références reliées aux maladies
Pistes exploratoires0Hypothèses non validées
10635 résultats correspondants · 41 visibles sur cette page dans le périmètre Toutes les maladies
Niveau clinique

Études et traitements 5743

Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.

Molécule / élément Maladie / population Objectif Phase / stade Statut / preuve Mécanisme / résumé Source Détail
Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… Maladie coronarienne À vérifier Non applicable NOT_YET_RECRUITING The objective of this study is to obtain experience with new and modified… À vérifier ClinicalTrials.gov 2026-11-09 21:03:06 Détail
SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… Maladie coronarienne Traitement symptomatique Non applicable NOT_YET_RECRUITING This is an early study of a catheter-based minimally invasive procedure ca… À vérifier ClinicalTrials.gov 2026-11-09 21:03:06 Détail
Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… Maladie coronarienne Thérapie génique À vérifier NOT_YET_RECRUITING In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier ClinicalTrials.gov 2026-11-09 21:03:06 Détail
Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS Maladie coronarienne Traitement symptomatique Non applicable NOT_YET_RECRUITING Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier ClinicalTrials.gov 2026-11-09 21:03:06 Détail
Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System Maladie coronarienne Traitement symptomatique Non applicable RECRUITING This early feasibility study is evaluating the safety and performance of t… À vérifier ClinicalTrials.gov 2026-11-09 21:03:05 Détail
Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… Maladie coronarienne À vérifier Phase 4 NOT_YET_RECRUITING Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier ClinicalTrials.gov 2026-11-09 21:03:05 Détail
Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… Maladie coronarienne Traitement symptomatique Non applicable RECRUITING This randomized single-blind controlled trial aims to compare the effectiv… À vérifier ClinicalTrials.gov 2026-11-09 21:03:05 Détail
Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… Maladie coronarienne À vérifier Non applicable COMPLETED Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier ClinicalTrials.gov 2026-11-09 21:03:05 Détail
Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) Maladie coronarienne Immunomodulation · Traitement symptomatique Non applicable NOT_YET_RECRUITING This pilot study will test an innovative way to establish how pain medicin… À vérifier ClinicalTrials.gov 2026-11-09 21:03:05 Détail
Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… Maladie coronarienne À vérifier Phase 3 RECRUITING In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier ClinicalTrials.gov 2026-11-09 21:03:05 Détail
Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation Maladie coronarienne Ralentissement de la progression Non applicable RECRUITING Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier ClinicalTrials.gov 2026-11-09 21:03:05 Détail
Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… Maladie coronarienne Traitement symptomatique Non applicable RECRUITING This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier ClinicalTrials.gov 2026-11-09 21:03:05 Détail
TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… Maladie coronarienne À vérifier À vérifier RECRUITING \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier ClinicalTrials.gov 2026-11-09 21:03:05 Détail
This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… Maladie coronarienne Traitement symptomatique Non applicable RECRUITING Although advances in treatment and patient management have considerably im… À vérifier ClinicalTrials.gov 2026-11-09 21:03:05 Détail
Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction Maladie coronarienne À vérifier Phase 4 ACTIVE_NOT_RECRUITING The primary objective of this study is to evaluate the effectiveness of ea… À vérifier ClinicalTrials.gov 2026-11-09 21:03:04 Détail
Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… Maladie coronarienne Thérapie génique Non applicable RECRUITING The goal of this clinical trial is to learn which treatment strategies imp… À vérifier ClinicalTrials.gov 2026-11-09 21:03:04 Détail
No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… Maladie coronarienne À vérifier Phase 4 COMPLETED The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier ClinicalTrials.gov 2026-11-09 21:03:04 Détail
Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm Maladie coronarienne À vérifier Non applicable RECRUITING This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier ClinicalTrials.gov 2026-11-09 21:03:04 Détail
26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… Myopathies Traitement symptomatique Non applicable NOT_YET_RECRUITING This randomized split-face study aims to compare the effects of 26G and 30… À vérifier ClinicalTrials.gov 2026-11-09 21:02:59 Détail
ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… Myopathies À vérifier Phase 1 RECRUITING This is an open-label phase 1 study to determine the safety and tolebility… À vérifier ClinicalTrials.gov 2026-11-09 21:02:59 Détail
Découverte scientifique

Recherches et trouvailles 21

Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.

Molécule / élément Maladie / population Objectif Phase / stade Statut / preuve Mécanisme / résumé Source Détail
4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation Sclérose latérale amyotrophique Neuroprotection · Immunomodulation Découverte fondamentale Exploratoire Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… Revue scientifique 2024-07-01 Détail
Bibliographie

Publications 4871

Références bibliographiques de la base locale et accès à leur source originale.

Molécule / élément Maladie / population Objectif Phase / stade Statut / preuve Mécanisme / résumé Source Détail
Multidimensional burden of scarring alopecia in women: findings from… PRIMUS · PMID 42404377 Migraine Immunomodulation · Traitement symptomatique Publication PubMed Voir la publication source Primary cicatricial alopecias are rare inflammatory disorders that disproportionately affect women and can cause perman… International journal of women's dermatology 2026-08-16 19:23:47 Source
Nutritional considerations for glucagon-like peptide-based therapies:… PRIMUS · PMID 42529748 Migraine À vérifier Publication PubMed Voir la publication source Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and dual glucose-dependent insulinotropic polypeptide (GIP) and G… Obesity pillars 2026-08-16 19:23:47 Source
Flunarizine and cinnarizine in the prophylaxis of vestibular migraine… Flunarizine · PMID 42572044 Migraine Ralentissement de la progression Publication PubMed Voir la publication source Vestibular migraine (VM) and migraine-associated Menière's disease (MAMD) are common causes of recurrent vertigo, often… European archives of oto-rhino-laryngology : official… 2026-08-16 19:23:46 Source
Observation of the therapeutic effect of flunarizine capsules combine… Flunarizine · PMID 42209266 Migraine Traitement symptomatique Publication PubMed Voir la publication source The Epley manoeuvre is the standard treatment for benign paroxysmal positional vertigo (BPPV) and flunarizine shows pot… Annals of human biology 2026-08-16 19:23:46 Source
Investigating the effects of antidepressants on measures of insulin r… Amitriptyline · PMID 42323987 Migraine À vérifier Publication PubMed Voir la publication source Persons with depression are disproportionately at risk for developing insulin resistance. Replicated evidence indicates… Journal of affective disorders 2026-08-16 19:23:45 Source
Towards the automatic detection of activities of daily living using e… CAVA Device · PMID 39746296 Maladie d’Alzheimer À vérifier Publication PubMed Voir la publication source Early diagnosis of neurodegenerative diseases, such as Alzheimer's disease, improves treatment and care outcomes for pa… Computers in biology and medicine 2026-08-16 19:23:44 Source
Effects of a programmed reflexology therapy on sleep quality, insomni… foot reflexology · PMID 42537947 Migraine Traitement symptomatique Publication PubMed Voir la publication source Poor sleep quality is closely associated with autonomic dysregulation and increased risks of cardiovascular, metabolic,… Complementary therapies in medicine 2026-08-16 19:23:39 Source
Non-Pharmacological Constipation Management in People With Neurodegen… foot reflexology · PMID 42459041 Maladie de Parkinson · Sclérose en plaques Traitement symptomatique Publication PubMed Voir la publication source Constipation is a common symptom among people with neurodegenerative diseases (PWND), with prevalence ranging from 25.2… Western journal of nursing research 2026-08-16 19:23:39 Source
Short-term effects of foot reflexology on pain, anxiety, and physiolo… foot reflexology · PMID 42574854 Migraine Traitement symptomatique Publication PubMed Voir la publication source Shoulder and neck pain (SNP) is a common musculoskeletal complaint among women and is often accompanied by heightened a… Acta psychologica 2026-08-16 19:23:39 Source
Bridging Objective and Subjective Data: A Comprehensive Architecture… A Study of Wearable Devices to Predict Migraines · PMID 42175179 Migraine À vérifier Publication PubMed Voir la publication source This study presents a secure, end-to-end architecture for multimodal health data collection and integration using a mul… Studies in health technology and informatics 2026-08-16 19:23:36 Source
Digital phenotyping for migraine: A game-changer for research and man… A Study of Wearable Devices to Predict Migraines · PMID 40734464 Migraine Traitement symptomatique · Thérapie génique Publication PubMed Voir la publication source Migraine is a complex neurobiological disorder characterized by diverse phenotypes and unpredictable therapy outcomes.… Cephalalgia : an international journal of headache 2026-08-16 19:23:36 Source
Heart rate variability as a predictor of migraine: Sleep-time data an… A Study of Wearable Devices to Predict Migraines · PMID 41607086 Migraine Thérapie génique Publication PubMed Voir la publication source BackgroundMigraine is a complex neurological disorder characterized by recurrent, often debilitating headaches. Current… Technology and health care : official journal of the E… 2026-08-16 19:23:36 Source
[Effectiveness of physiotherapeutic treatment interventions on pain i… The Effect of Two Different Massages on Migraine · PMID 34936005 Migraine Traitement symptomatique Publication PubMed Voir la publication source According to the current guidelines preventive treatment of migraine should consist of a combination of pharmacological… Schmerz (Berlin, Germany) 2026-08-16 19:23:32 Source
Needs-based epilepsy follow-up: seizure control, treatment adherence… Eptinezumab · PMID 42166924 Migraine Thérapie génique Publication PubMed Voir la publication source The use of needs-based epilepsy follow-up has increased due to technical solutions and resource constraints, however li… Epilepsy & behavior : E&B 2026-08-16 19:23:29 Source
Ultrasound-Guided Greater Auricular Nerve Block: A Pilot Study for Pa… Greater Auricular Nerve Block · PMID 42545492 Migraine Traitement symptomatique · Thérapie génique Publication PubMed Voir la publication source Post-auricular procedures in aesthetic surgery, including hyaluronic acid filler correction for "lying ears," otoplasty… Aesthetic plastic surgery 2026-08-16 19:23:28 Source
Efficacy of Greater Occipital Nerve Block versus Sphenopalatine Gangl… greater occipital nerve block · PMID 41656284 Migraine Traitement symptomatique Publication PubMed Voir la publication source Postdural puncture headache (PDPH) is a common and often debilitating complication following lumbar puncture, affecting… Annals of African medicine 2026-08-16 19:23:27 Source
Peripheral nerve blocks in primary headaches and neuralgias: a six-co… greater occipital nerve block · PMID 42497573 Migraine À vérifier Publication PubMed Voir la publication source Peripheral nerve blocks (PNBs) represent an accessible, minimally invasive therapeutic approach for headache disorders;… Journal of clinical neuroscience : official journal of… 2026-08-16 19:23:27 Source
A profile on the Cefaly Dual trigeminal neurostimulator for acute and… Neurostimulator · PMID 42334008 Migraine Ralentissement de la progression · Traitement symptomatique Publication PubMed Voir la publication source Migraine is one of the leading causes of disability worldwide. Neuromodulation is a non-pharmacologic class of treatmen… Expert review of medical devices 2026-08-16 19:23:26 Source
Common Mechanisms in Migraine, Migraine-Related Neck Pain, and Low Ba… Mechanism-Based Cervical Rehabilitation for Chronic Migraine · PMID 42521953 Migraine Traitement symptomatique Publication PubMed Voir la publication source Chronic pain conditions, such as migraine, migraine-related neck pain (NP), and low back pain (LBP), are central pain p… Pain and therapy 2026-08-16 19:23:26 Source
Electrode Type and Long-Term Clinical Response to Responsive Neurosti… Neurostimulator · PMID 41439767 Migraine À vérifier Publication PubMed Voir la publication source Responsive neurostimulation (RNS) is a neuromodulatory treatment of medically refractory epilepsy involving the implant… Neurosurgery 2026-08-16 19:23:26 Source
Exploration — prudence

Pistes exploratoires 0

Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.

Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
Molécule / élément Maladie / population Objectif Phase / stade Statut / preuve Mécanisme / résumé Source Détail
Aucune piste exploratoire ne correspond aux filtres.