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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Transitional Palliative Care for Family Caregivers: Outcomes From a R… Corabotase dose A · PMID 39111586 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Patients receiving inpatient palliative care often face physical and psychological uncertainties during transitions out… | Journal of pain and symptom management 2026-08-16 19:24:01 | Source |
| Effect of Extracorporeal Shock Wave Therapy Combined With Kinesio Tap… I-SPY-RCT — Intervention for Sleep and Pain in Youth: A Randomized Controlled Trial · PMID 418… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source To evaluate the main effects of extracorporeal shock wave therapy (ESWT) and Kinesio taping (KT) and their interaction… | Archives of physical medicine and rehabilitation 2026-08-16 19:23:58 | Source |
| Efficacy and safety of transcutaneous electrical nerve stimulation in… I-SPY-RCT — Intervention for Sleep and Pain in Youth: A Randomized Controlled Trial · PMID 424… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Itching is a common and distressing clinical manifestation following burns, which severely impairs patient quality of l… | BMJ open 2026-08-16 19:23:58 | Source |
| Preoperative photobiomodulation reduces pain in molar surgery: A, dou… I-SPY-RCT — Intervention for Sleep and Pain in Youth: A Randomized Controlled Trial · PMID 423… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Postoperative pain, swelling, and functional limitations are common after mandibular third molar surgery, affecting rec… | Journal of dentistry 2026-08-16 19:23:58 | Source |
| Percutaneous closure strategy in patients with patent foramen ovale a… Transcatheter Closure of Patent Foramen Ovale · PMID 42218325 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source In transcatheter closure of patent foramen ovale (PFO) associated with cryptogenic stroke (CS), a small coexisting atri… | Cardiovascular intervention and therapeutics 2026-08-16 19:23:57 | Source |
| Steering clear of the Chiari network pitfall in the transoesophageal… Transcatheter Closure of Patent Foramen Ovale · PMID 41618633 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | European heart journal. Cardiovascular Imaging 2026-08-16 19:23:57 | Source |
| Transcatheter Closure of Patent Foramen Ovale - A Single Center Exper… Transcatheter Closure of Patent Foramen Ovale · PMID 42092276 | Accident vasculaire cérébral · Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source A patent foramen ovale (PFO) is present in 20%-30% of the adult population. It is usually found in patients incidentall… | The Journal of surgical research 2026-08-16 19:23:57 | Source |
| A comparison of reduced-dose prasugrel and standard-dose clopidogrel… Prasugrel 5mg · PMID 27823681 | Maladie coronarienne · Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Elderly patients display higher on clopidogrel platelet reactivity as compared with younger patients. Treatment with pr… | American heart journal 2026-08-16 19:23:56 | Source |
| Residual platelet reactivity and outcomes with 5 mg prasugrel therapy… Prasugrel 5mg · PMID 25139323 | Migraine | À vérifier | Publication | PubMed | Voir la publication source In acute coronary syndrome (ACS) patients older than 75 years old, prasugrel 10 mg maintenance therapy has shown less c… | International journal of cardiology 2026-08-16 19:23:56 | Source |
| The influence of body size on the pharmacodynamic and pharmacokinetic… Prasugrel 5mg · PMID 25022828 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Patients treated with clopidogrel who have higher body size exhibit greater platelet reactivity than patients with lowe… | Thrombosis research 2026-08-16 19:23:56 | Source |
| Efficacy, Safety, and Tolerability of Atogepant in Migraine Patients… Atogepant · PMID 42154195 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Atogepant is an oral calcitonin gene-related peptide (CGRP) receptor antagonist approved for migraine prevention; howev… | Neurology and therapy 2026-08-16 19:23:53 | Source |
| Online interest in calcitonin gene-related peptide-therapies: An info… Ubrogepant · PMID 42265869 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source To evaluate changes in public interest in calcitonin gene-related peptide therapies associated with major product lifec… | Headache 2026-08-16 19:23:50 | Source |
| Population Pharmacokinetics and Exposure-Response Analyses for Ubroge… Ubrogepant · PMID 42212509 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source A population pharmacokinetic (popPK) model was developed for ubrogepant using data from 10 Phase 1, 1 Phase 2, and 2 Ph… | Journal of clinical pharmacology 2026-08-16 19:23:50 | Source |
| The pharmacology of gepants in migraine: A scoping review on mechanis… Ubrogepant · PMID 42265882 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Calcitonin gene-related peptide (CGRP) is a key mediator in migraine pathophysiology, and the development of gepants, n… | Headache 2026-08-16 19:23:50 | Source |
| Clinical associations during the year before Parkinson's disease diag… Propranolol · PMID 42261249 | Accident vasculaire cérébral · Maladie de Parkinson | À vérifier | Publication | PubMed | Voir la publication source Characterizing clinical associations before Parkinson's disease (PD) diagnosis may improve understanding of the diagnos… | Annals of medicine 2026-08-16 19:23:49 | Source |
| Oral propranolol treatment safety in infantile hemangiomas. Propranolol · PMID 42179355 | Migraine · Myopathies · Myopathies | À vérifier | Publication | PubMed | Voir la publication source Infantile hemangiomas are common and can be treated with propranolol. Cardiovascular side effects are a potential risk… | The Journal of dermatological treatment 2026-08-16 19:23:49 | Source |
| Propranolol enhances the oncolytic effect of newcastle disease virus… Propranolol · PMID 41866332 | Migraine · Myopathies · Myopathies | À vérifier | Publication | PubMed | Voir la publication source Canine mammary tumors (CMT), the most common neoplasms in intact female dogs, lack effective treatments for advanced ca… | The veterinary quarterly 2026-08-16 19:23:49 | Source |
| A Passiflora incarnata extract exerts multi-target effects on selecte… Melatonin · PMID 42462921 | Épilepsie · Lupus · Migraine · Sclérose latérale amyotrophique · Migr… | Thérapie génique | Publication | PubMed | Voir la publication source Since ancient times, passionflower (Passiflora incarnata L.) is used to treat insomnia, nervousness, anxiety, and other… | Journal of ethnopharmacology 2026-08-16 19:23:48 | Source |
| Hormone-metabolism crosstalk in plants: an integrated signaling netwo… Melatonin · PMID 42533527 | Épilepsie · Lupus · Migraine · Sclérose latérale amyotrophique · Migr… | Remyélinisation indirecte / réparation | Publication | PubMed | Voir la publication source Plant growth, stress adaptation, and productivity depend on the continuous exchange of information between hormone sign… | Plant signaling & behavior 2026-08-16 19:23:48 | Source |
| Impact of Mild Traumatic Brain Injury (mTBI) on CYP2D6 Activity and t… Melatonin · PMID 42153180 | Épilepsie · Lupus · Migraine · Sclérose latérale amyotrophique · Migr… | À vérifier | Publication | PubMed | Voir la publication source Mild traumatic brain injury (mTBI) may disrupt hepatic cytochrome P-450 enzyme activity, potentially altering drug phar… | Iranian journal of pharmaceutical research : IJPR 2026-08-16 19:23:48 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||