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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Optical Fiber Surface Plasmon Resonance Sensor for Glyceryl Tributyra… Glycerol Tributyrate · PMID 38656893 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Glycerol tributyrate as a low-density lipoprotein plays a crucial role in drug development and food safety. In this wor… | Analytical chemistry 2026-08-16 19:24:34 | Source |
| Synergistic Modification of Polylactic Acid Fibrous Membranes with Im… Glycerol Tributyrate · PMID 40254794 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Reusable and biodegradable facemasks with enhanced antibacterial and mechanical functions are considered sustainable pe… | ACS applied materials & interfaces 2026-08-16 19:24:34 | Source |
| Efficacy of acupuncture therapies for polycystic ovary syndrome: a ne… fire needling combined with filiform needling · PMID 42591356 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Polycystic ovary syndrome (PCOS) is a prevalent gynecological disorder that significantly impairs quality of life and r… | Frontiers in medicine 2026-08-16 19:24:33 | Source |
| Refractory Periungual Warts Treated with Filiform Fire Needle Combine… fire needling combined with filiform needling · PMID 42226748 | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Periungual warts, caused by Human Papillomavirus (HPV) infection, are a therapeutic challenge due to their proximity to… | Clinical, cosmetic and investigational dermatology 2026-08-16 19:24:33 | Source |
| ['s experience in treatment of knee osteoarthritis with 's filiform f… fire needling combined with filiform needling · PMID 41987451 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source This paper introduces the clinical experience of Professor in treatment of knee osteoarthritis (KOA) using "'s filiform… | Zhongguo zhen jiu = Chinese acupuncture & moxibustion 2026-08-16 19:24:33 | Source |
| Investigating the effects of chlorogenic acid on novel object recogni… Ketamine · PMID 42571303 | Épilepsie · Migraine · Migraine · Épilepsie | Neuroprotection · Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Schizophrenia is a severe neuropsychiatric disorder characterized by positive, negative, cognitive, mood-related, and m… | IBRO neuroscience reports 2026-08-16 19:24:32 | Source |
| Ketamine preserves perineuronal nets in chronic stressed mice brain t… Ketamine · PMID 42571376 | Épilepsie · Migraine · Migraine · Épilepsie | Immunomodulation | Publication | PubMed | Voir la publication source Deeper understanding of ketamine's mechanism of action would contribute to the discovery of novel therapeutic targets w… | IBRO neuroscience reports 2026-08-16 19:24:32 | Source |
| Pediatric Acupuncture Safety: A Scoping Review. filiform needling · PMID 42179706 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Previous research studies have indicated that acupuncture may be a promising treatment for several pediatric conditions… | Global advances in integrative medicine and health 2026-08-16 19:24:32 | Source |
| Substance use and mental health outcomes among gay and bisexual men i… Ketamine · PMID 42494974 | Épilepsie · Migraine · Migraine · Épilepsie | Traitement symptomatique | Publication | PubMed | Voir la publication source This study investigated the prevalence of substance use among gay and bisexual men in South Korea and examined its asso… | Addictive behaviors reports 2026-08-16 19:24:32 | Source |
| [Long-term clinical effect of fire needling on knee osteoarthritis]. filiform needling · PMID 42116777 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source To observe the long-term clinical efficacy and safety of fire needling in the treatment of knee osteoarthritis. Sixty p… | Zhongguo zhen jiu = Chinese acupuncture & moxibustion 2026-08-16 19:24:32 | Source |
| Ditan Decoction alleviates glutamate excitotoxicity in an Aβ-induced… ditan · PMID 42320774 | Maladie d’Alzheimer | Neuroprotection | Publication | PubMed | Voir la publication source Alzheimer's disease (AD), as the most prevalent form of dementia among the elders, poses a major global health challeng… | Journal of ethnopharmacology 2026-08-16 19:24:28 | Source |
| Impact of antiviral treatment and initiation time on mother-to-child… ditan · PMID 42003011 | Migraine | À vérifier | Publication | PubMed | Voir la publication source To further reduce mother-to-child transmission (MTCT), this study aims to explore the factors influencing MTCT rate in… | Virulence 2026-08-16 19:24:28 | Source |
| Impact of midwife-led continuous support during childbirth on materna… ditan · PMID 42373140 | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source To evaluate the association between integrated midwife-led continuous labor support with postpartum care and maternal a… | The journal of maternal-fetal & neonatal medicine : th… 2026-08-16 19:24:28 | Source |
| Effectiveness and safety of sumatriptan 85 mg/naproxen sodium 500 mg… combination of sumatriptan and naproxen · PMID 42591283 | Migraine | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source This prospective multicenter observational study, designed by the Greek Research Alliance for the Study of Headache and… | Frontiers in neurology 2026-08-16 19:24:27 | Source |
| CGRP: the immune system's double agent - context-dependent roles in i… anti-CGRP monoclonal antibodies · PMID 42488654 | Migraine · Cancer | Immunomodulation | Publication | PubMed | Voir la publication source Calcitonin gene-related peptide (CGRP) is traditionally recognized as a key mediator of nociception and vasodilation. H… | Frontiers in immunology 2026-08-16 19:24:26 | Source |
| Perceived comfort with migraine treatments and control of migraine sy… gepants · PMID 42517716 | Migraine | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source This study was conducted to identify patient characteristics and medication factors associated with perceived comfort w… | Headache 2026-08-16 19:24:26 | Source |
| STS101 nasal powder as a new treatment option for acute migraine with… gepants · PMID 42217235 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Although effective acute migraine therapies are available, unmet treatment needs such as nausea, vomiting, or delayed g… | Expert review of neurotherapeutics 2026-08-16 19:24:26 | Source |
| Cobalt-induced charge redistribution and lattice distortion enable ac… Eptinezumab 100 or 300 mg ev · PMID 42335689 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Cation substitution provides an effective route to regulate electrochemical kinetics in NASICON-type cathodes, yet the… | Journal of colloid and interface science 2026-08-16 19:24:25 | Source |
| High-temperature reversible emission in a simple Schiff base: activat… Eptinezumab 100 or 300 mg ev · PMID 42348974 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Thermally robust solid-state emission remains rare among simple organic chromophores because elevated temperature usual… | Spectrochimica acta. Part A, Molecular and biomolecula… 2026-08-16 19:24:25 | Source |
| Integrated multispectroscopic and DFT analysis of molecular heterogen… Eptinezumab 100 or 300 mg ev · PMID 42349151 | Migraine | À vérifier | Publication | PubMed | Voir la publication source This study presents the first systematic analysis of the molecular architecture of asphaltenes isolated from Garabagh p… | Spectrochimica acta. Part A, Molecular and biomolecula… 2026-08-16 19:24:25 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||