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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Use and safety of corticosteroid injections in joints and musculoskel… Methylprednisolone 40 MG Injection · PMID 40015722 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Intra-articular corticosteroid (IACS) injection and peri-articular corticosteroid injection are commonly used to treat… | Regional anesthesia and pain medicine 2026-08-16 19:24:47 | Source |
| Biofeedback in the prophylactic treatment of medication overuse heada… Neurofeedback for Episodic Migraine · PMID 27655371 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Medication overuse headache (MOH) is a major clinical concern and a common health risk. Recent literature stressed the… | The journal of headache and pain 2026-08-16 19:24:46 | Source |
| Neurofeedback and biofeedback with 37 migraineurs: a clinical outcome… Neurofeedback for Episodic Migraine · PMID 20205867 | Migraine | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Traditional peripheral biofeedback has grade A evidence for effectively treating migraines. Two newer forms of neurobio… | Behavioral and brain functions : BBF 2026-08-16 19:24:46 | Source |
| L5-S1 basivertebral nerve ablation for chronic vertebrogenic low back… Chiropractic Care · PMID 42582823 | Migraine | Ralentissement de la progression · Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Basivertebral nerve ablation (BVNA) is an established treatment for vertebrogenic low back pain associated with Modic e… | Journal of spine surgery (Hong Kong) 2026-08-16 19:24:45 | Source |
| Latent Patterns of Complementary and Integrative Health Therapy Utili… Chiropractic Care · PMID 42503189 | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Complementary and integrative health (CIH) therapies offer safe and effective alternatives for pain management, and use… | Pain medicine (Malden, Mass.) 2026-08-16 19:24:45 | Source |
| Resolution of Treatment-Resistant Vertigo and Suspected Ménière's Dis… Chiropractic Care · PMID 42534238 | Migraine · Cancer | Traitement symptomatique | Publication | PubMed | Voir la publication source Ménière's disease and related peripheral vestibular disorders are notoriously difficult to manage, and many patients re… | Cureus 2026-08-16 19:24:45 | Source |
| E-selectin and TFPI are associated with carotid intima-media thicknes… Atorvastatin 20mg · PMID 17889518 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source MIAMI was a prospective multicenter clinical study designed to investigate the relationship between changes in carotid… | Nutrition, metabolism, and cardiovascular diseases : N… 2026-08-16 19:24:43 | Source |
| Evaluation of Flavonoid-rich Fraction of Aerial Part Extract in Ather… Atorvastatin 20mg · PMID 37807415 | Migraine | Neuroprotection · Ralentissement de la progression · Immunomodulation | Publication | PubMed | Voir la publication source is a tiny, upright herb that contains a variety of chemical components, including alkaloids, glycosides, mucilage, prot… | Combinatorial chemistry & high throughput screening 2026-08-16 19:24:43 | Source |
| Expert consensus on drug treatment of chronic subdural hematoma. Atorvastatin 20mg · PMID 34809712 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Chronic subdural hematoma (CSDH) is a chronic space-occupying lesion formed by blood accumulation between arachnoid and… | Chinese neurosurgical journal 2026-08-16 19:24:43 | Source |
| Effects of erenumab on migraine aura frequency: a REFORM study. Erenumab Dose 1 · PMID 41888647 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Anti-calcitonin gene-related peptide (CGRP) monoclonal antibodies effectively prevent migraine headache, but their impa… | The journal of headache and pain 2026-08-16 19:24:39 | Source |
| Efficacy and Safety of Erenumab in Adults With Medication Overuse Hea… Erenumab Dose 1 · PMID 40838472 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Erenumab-induced medication overuse headache (MOH) remission in participants with chronic migraine (CM) in a prospectiv… | European journal of neurology 2026-08-16 19:24:39 | Source |
| Erenumab for Chronic Cluster Headache: A Randomized Clinical Trial. Erenumab Dose 1 · PMID 40526384 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Calcitonin gene-related peptide (CGRP) is involved in the pathophysiology of cluster headache (CH). Prophylactic pharma… | JAMA network open 2026-08-16 19:24:39 | Source |
| Neuro-Immune Axis in Trauma-Induced Heterotopic Ossification: Mechani… Erenumab Dose 2 · PMID 42121928 | Migraine | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Trauma-induced heterotopic ossification (tHO) is characterized by aberrant ectopic bone formation in soft tissue follow… | Cells 2026-08-16 19:24:39 | Source |
| Advances in ERAS to Reduce the Incidence of Chronic Post-Surgical Pai… Lidocaine Procedure · PMID 42138101 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Chronic postsurgical pain (CPSP) remains a clinically significant complication following major surgery, contributing to… | Journal of investigative surgery : the official journa… 2026-08-16 19:24:38 | Source |
| Comparison of a TrachoSpray Device and Manual Lidocaine Spray on Hemo… Lidocaine Procedure · PMID 41797600 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Postoperative sore throat (POST) is an distressing complication following endotracheal intubation, particularly with do… | Journal of investigative surgery : the official journa… 2026-08-16 19:24:38 | Source |
| Lidocaine Spray Versus Viscous Lidocaine Solution Plus Lidocaine Spra… Lidocaine Procedure · PMID 42559051 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Non-sedated esophagogastroduodenoscopy (EGD) is preferred in patients at risk from sedatives. However, achieving effect… | DEN open 2026-08-16 19:24:38 | Source |
| An eco-friendly triple quadrupole mass spectrometry approach for the… Lidocaine (drug) · PMID 42187176 | Migraine | À vérifier | Publication | PubMed | Voir la publication source N-nitrosamine compounds have been recognized for their carcinogenic properties. Compounds containing secondary and tert… | European journal of mass spectrometry (Chichester, Eng… 2026-08-16 19:24:37 | Source |
| Effects of a Lidocaine-Loaded Alginate/CMC/PEO Electrospun Nanofiber… Lidocaine (drug) · PMID 42075660 | Migraine | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source : Postoperative pain and intra-abdominal adhesions are common complications following surgery. Pain delays early mobili… | Medicina (Kaunas, Lithuania) 2026-08-16 19:24:37 | Source |
| The Anaesthetic Efficacy of Tetracaine and Oxymetazoline Compared Wit… Lidocaine (drug) · PMID 39286961 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Nasal anaesthetic-decongestant sprays are commonly used prior to nasal instrumentation, such as flexible and rigid nasa… | Clinical otolaryngology : official journal of ENT-UK ;… 2026-08-16 19:24:37 | Source |
| Functional characterization of cutinase genes NsCut1-NsCut4 in and th… Glycerol Tributyrate · PMID 40265120 | Migraine | Neuroprotection | Publication | PubMed | Voir la publication source Fishscale bamboo rhombic-spot, caused by , poses a significant threat to in Sichuan province. Based on genomic analysis… | Frontiers in plant science 2026-08-16 19:24:34 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||