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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| A Diagnostic Challenge in the Emergency Department: Acute Intermitten… Cabergoline 0.5 MG · PMID 42231991 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Acute intermittent porphyria is a rare metabolic disorder that often presents with recurrent abdominal pain and nonspec… | Cureus 2026-08-16 19:25:06 | Source |
| A novel germline CDH23 variant as a likely cause of an ultra-giant pr… Cabergoline 0.5 MG · PMID 41612354 | Cancer | Traitement symptomatique | Publication | PubMed | Voir la publication source Giant prolactinomas are defined as pituitary adenomas (PAs) ≥ 4 cm with plasma prolactin level > 1000 ng/ml with no oth… | Orphanet journal of rare diseases 2026-08-16 19:25:06 | Source |
| A heparan sulfate-mimetic derivative of botryosphaeran with antiviral… BOTOX · PMID 42531700 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Herpes is a viral disease with high worldwide prevalence. The lack of herpes vaccines and the growing viral resistance… | Carbohydrate research 2026-08-16 19:25:00 | Source |
| A Systematic Review on Administration of Botulinum Toxin in the Manag… BOTOX · PMID 41185533 | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Male sexual dysfunctions (SDs) like erectile dysfunction (ED), premature ejaculation (PE), and Peyronie's disease (PD)… | Andrology 2026-08-16 19:25:00 | Source |
| Effect of Preoperative Botulinum Toxin on the Outcome of Large Midlin… BOTOX · PMID 42596800 | Hypertension artérielle | Thérapie génique | Publication | PubMed | Voir la publication source Abdominal hernias with large fascial defects are very difficult to repair, and it is almost impossible to achieve midli… | ANZ journal of surgery 2026-08-16 19:25:00 | Source |
| A Phase 1, Randomized, Placebo-Controlled, Multiple-Dose, Double-Blin… Rimegepant 75mg daily dosing · PMID 41273248 | Migraine | À vérifier | Publication | PubMed | Voir la publication source This Phase 1, randomized, placebo-controlled, double-blind study assessed the pharmacokinetic profile of rimegepant (25… | Clinical pharmacology in drug development 2026-08-16 19:24:58 | Source |
| Treatment with a self-expanding endoprosthesis in patients with steno… TEMMA Endovascular Treatment · PMID 39402727 | Migraine | À vérifier | Publication | PubMed | Voir la publication source To assess 6-month safety and efficacy of a self-expanding stent graft placement to treat stenotic or thrombosed synthet… | The journal of vascular access 2026-08-16 19:24:55 | Source |
| Effects of Pentoxifylline on Peri-Implant Capsule Cellularity and Thi… Pharmacological prophylaxis · PMID 42589435 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Capsular contracture is a fibrotic foreign-body response to silicone implants, driven primarily by TGF-β1-mediated myof… | International journal of molecular sciences 2026-08-16 19:24:54 | Source |
| The Impact of E-Cigarettes and Heat-Not-Burn Tobacco on Postoperative… Pharmacological prophylaxis · PMID 41134080 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Tobacco smoke is an established risk factor of Crohn's disease (CD) postoperative recurrence; however, the effect of e-… | The American journal of gastroenterology 2026-08-16 19:24:54 | Source |
| The prevention of heterotopic ossification around the knee: a scoping… Pharmacological prophylaxis · PMID 42542554 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Evidence on prophylactic interventions to prevent heterotopic ossification (HO) around the knee is scarce. We conducted… | BMC musculoskeletal disorders 2026-08-16 19:24:54 | Source |
| Advice to Health Care Providers: Achieving Successful Organ Donation. Erenumab · PMID 42556494 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | The American journal of medicine 2026-08-16 19:24:53 | Source |
| Consumption of Ultra-Processed Foods and Increased Risks of Prostate… Erenumab · PMID 42567433 | Cancer | À vérifier | Publication | PubMed | Voir la publication source In the United States and worldwide, there is an increasing body of reliable evidence suggesting that ultra processed fo… | The American journal of medicine 2026-08-16 19:24:53 | Source |
| Integrating Nutrition and Physical Activity into the EXEMIG/01 Interd… EXEMIG/01 — EXErcise in MIGraine · PMID 42356280 | Migraine | Ralentissement de la progression | Publication | PubMed | Voir la publication source Migraine (MIG) management guidelines support a comprehensive approach combining medication, therapeutic patient educati… | Nutrients 2026-08-16 19:24:52 | Source |
| Ginger for the treatment and prevention of migraine headaches: a syst… Active drug for acute migraine treatment · PMID 42601183 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source To determine the efficacy of ginger (either stand-alone or as an adjunct treatment) for the treatment and management of… | BMJ evidence-based medicine 2026-08-16 19:24:51 | Source |
| NOP receptor activation counteracts stress-induced migraine-like beha… Active drug for acute migraine treatment · PMID 42242546 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Stress is a major trigger of migraine, yet the underlying mechanisms remain unclear. Previous evidence supports the noc… | Neuropharmacology 2026-08-16 19:24:51 | Source |
| An Emerging Autoimmune Neuroinflammatory Disease: Myelin Oligodendroc… Methylprednisolone 40 MG Injection · PMID 40952817 | Sclérose en plaques | Remyélinisation · Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Myelin oligodendrocyte glycoprotein antibody disease (MOGAD) is a discrete autoimmune, neuroinflammatory demyelinating… | Annals of African medicine 2026-08-16 19:24:47 | Source |
| An evaluation of peripheral nerve damage that may develop following i… Bupivacaine HCl 0.5% Injectable Solution · PMID 42251255 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source This study aimed to investigate the histopathological, electrophysiological, functional, biochemical, and inflammatory… | BMC anesthesiology 2026-08-16 19:24:47 | Source |
| Does Liposomal Bupivacaine Provide Superior Postoperative Analgesia C… Bupivacaine HCl 0.5% Injectable Solution · PMID 42284069 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Choosing the most effective pain management is important for enhancing functional recovery after surgery. The fascia il… | Clinical orthopaedics and related research 2026-08-16 19:24:47 | Source |
| Long-term durability of a time-limited methotrexate intervention in p… Methylprednisolone 40 MG Injection · PMID 42392130 | Migraine | Ralentissement de la progression · Immunomodulation | Publication | PubMed | Voir la publication source The TREAT EARLIER trial showed that a time-limited intervention with 12 months of methotrexate in individuals with arth… | The Lancet. Rheumatology 2026-08-16 19:24:47 | Source |
| The true benefit of the regional block in orthognathic surgery lies i… Bupivacaine HCl 0.5% Injectable Solution · PMID 41790271 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source PURPOSE: The objective of this study was to ascertain the actual benefits of regional analgesia in orthognathic surgery… | Oral and maxillofacial surgery 2026-08-16 19:24:47 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||