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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Diagnostic puzzles in primary amenorrhea: a report of 3 cases. Hormonal assessment · PMID 42524187 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Primary amenorrhea is a common referral indication in pediatric and adolescent endocrinology and can occur due to hypot… | JCEM case reports 2026-08-16 19:26:22 | Source |
| External Validation of EEG-Based Machine Learning Models for Continuo… Pressure stimuli · PMID 42600964 | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Machine learning (ML) has been used to predict subjective pain intensity from electroencephalographic (EEG) data. Howev… | The journal of pain 2026-08-16 19:26:22 | Source |
| Frequent antecedent nodules and diagnostic gaps in adrenocortical car… Hormonal assessment · PMID 42582611 | Migraine | Ralentissement de la progression | Publication | PubMed | Voir la publication source Adrenocortical carcinoma (ACC) is a rare and often fatal malignancy currently only cured by surgery. Large-scale studie… | Journal of the Endocrine Society 2026-08-16 19:26:22 | Source |
| TRPV4 mediates macrophage polarization involved in inflammatory root… Pressure stimuli · PMID 41990241 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source In clinical orthodontic treatment, mechanical pressure applied to the tooth root triggers orthodontically induced infla… | Channels (Austin, Tex.) 2026-08-16 19:26:22 | Source |
| Development of 2,8-diazaspiro[4.5]decan-3-ones as novel sigma-1 recep… Thermal stimuli · PMID 42447745 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Hyperalgesia is a common clinical condition that can be alleviated by blocking the sigma-1 receptor (σ1R). This study f… | Bioorganic chemistry 2026-08-16 19:26:21 | Source |
| Preparation of Oxide Nanofibers for Analysis by Transmission Electron… Thermal stimuli · PMID 42604437 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The low electronic conductivity and rigid structure make sample preparation for in situ transmission electron microscop… | Microscopy research and technique 2026-08-16 19:26:21 | Source |
| Role for TREK-1 as a polymodal sensor and regulator of cell activity. Thermal stimuli · PMID 42153246 | Cancer | Neuroprotection · Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source TREK-1 (KCNK2) is a polymodal two-pore domain potassium (K2P) channel that functions as a background K conductance and… | Channels (Austin, Tex.) 2026-08-16 19:26:21 | Source |
| A Meta-analysis of Randomized Controlled Trials of Adjunctive Biophys… pulsed electromagnetic field · PMID 42592349 | Migraine | Remyélinisation indirecte / réparation | Publication | PubMed | Voir la publication source Impaired bone regeneration remains a major challenge in orthopedic reconstruction, particularly in distraction osteogen… | Orthopedic reviews 2026-08-16 19:26:20 | Source |
| Design of a wearable compact pulsed electromagnetic field (PEMF) devi… pulsed electromagnetic field · PMID 42557268 | Migraine | À vérifier | Publication | PubMed | Voir la publication source This article explains the design and experimental results of a compact, wearable pulsed electromagnetic field (PEMF) ge… | Scientific reports 2026-08-16 19:26:20 | Source |
| Effects of Pulsed Electromagnetic Field Application on Glucose Metabo… pulsed electromagnetic field · PMID 42504996 | Migraine | Neuroprotection | Publication | PubMed | Voir la publication source The present study aimed to evaluate the effects of pulsed electromagnetic field (PEMF) exposure on glucose metabolism-r… | Bioelectromagnetics 2026-08-16 19:26:20 | Source |
| Discrete Choice Experiment to Understand Japanese Patients' and Physi… Erenumab Auto-Injector · PMID 36848008 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Self-injectable calcitonin gene-related peptide (CGRP) monoclonal antibody (mAb) auto-injectors and non-CGRP oral medic… | Neurology and therapy 2026-08-16 19:26:18 | Source |
| High-flow nasal cannula oxygenation in sedated endoscopy for high-ris… Propofol · PMID 42504139 | Maladie coronarienne · Migraine · Migraine | À vérifier | Publication | PubMed | Voir la publication source Hypoxemia is the most common adverse event during sedated gastrointestinal endoscopy. Patients with high obstructive sl… | Annals of medicine 2026-08-16 19:26:17 | Source |
| Going high-throughput: Dynamic conformations and interactions . Precision · PMID 42604037 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Proteins are intrinsically dynamic molecules that continuously explore conformational ensembles to execute biological f… | Magnetic resonance letters 2026-08-16 19:26:14 | Source |
| Quadratus Lumborum Block During Minimally Invasive Colorectal Surgery… Ketorolac · PMID 42228437 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Multimodal opioid-sparing analgesia has been well established as a component of enhanced recovery after surgery protoco… | Diseases of the colon and rectum 2026-08-16 19:26:14 | Source |
| Safety and Efficacy of Ketorolac in the Management of Pain for Postop… Ketorolac · PMID 41823440 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source PurposeKetorolac is commonly cautioned with a possible effect of bleeding. The safety and efficacy of Ketorolac has not… | The American surgeon 2026-08-16 19:26:14 | Source |
| The Efficacy and Safety of Ketamine or Ketorolac Compared to Opioids… Ketorolac · PMID 41656528 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | The Annals of pharmacotherapy 2026-08-16 19:26:14 | Source |
| The perspective of artificial intelligence for NMR. Precision · PMID 42518522 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Nuclear magnetic resonance (NMR) spectroscopy is an indispensable analytical technique in chemistry, biology, and medic… | Magnetic resonance letters 2026-08-16 19:26:14 | Source |
| Contribution of intravenous medication diluent fluid composition on t… Dextrose 5% in water · PMID 40689261 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Intravenous solutions such as dextrose 5% in water and 0.9% sodium chloride (normal saline) differ in electrolyte compo… | SAGE open medicine 2026-08-16 19:26:07 | Source |
| Enteral free water vs. parenteral dextrose 5% in water for the treatm… Dextrose 5% in water · PMID 37638970 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Effective treatment options for patients with hypernatremia are limited. Free water administration (parenterally or ent… | Journal of anesthesia 2026-08-16 19:26:07 | Source |
| Management of Recurrent Laryngeal Nerve Injury During Radiofrequency… Dextrose 5% in water · PMID 35415225 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | AACE clinical case reports 2026-08-16 19:26:07 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||