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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Comparative outcomes of proton and photon therapy in the management o… radiation therapy · PMID 42414660 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Malignant Peripheral Nerve Sheath Tumors (MPNSTs) are aggressive sarcomas often arising in the spine, characterized by… | European spine journal : official publication of the E… 2026-07-08 12:06:45 | Source |
| Association Between Geriatric Nutritional Risk Index and Gemcitabine… paclitaxel albumin-stabilized nanoparticle formulation · PMID 42373239 | Cancer | À vérifier | Publication | PubMed | Voir la publication source This retrospective study evaluated the impact of Geriatric Nutritional Risk Index (GNRI) group on time to treatment fai… | Anticancer research 2026-07-08 12:06:44 | Source |
| Nab-paclitaxel or Paclitaxel Treatment for Relapsed Small Cell Lung C… paclitaxel albumin-stabilized nanoparticle formulation · PMID 42373285 | Cancer | Ralentissement de la progression | Publication | PubMed | Voir la publication source Relapsed small cell lung cancer (SCLC) treatment has limited evidence-based options. Solvent-based paclitaxel (PTX) and… | Anticancer research 2026-07-08 12:06:44 | Source |
| Responsive stimulation of the thalamus for idiopathic generalized epi… RNS® System · PMID 42233958 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source This study was undertaken to evaluate the safety and effectiveness of responsive thalamic stimulation as adjunctive the… | Epilepsia 2026-07-08 12:06:44 | Source |
| Thalamocortical seizure onset patterns in drug-resistant focal epilep… RNS® System · PMID 42396599 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Drug-resistant epilepsy affects tens of millions of people worldwide and is associated with considerable morbidity and… | Brain communications 2026-07-08 12:06:44 | Source |
| A review of the efficacy and safety of eslicarbazepine acetate in the… BIA 2-093 · PMID 26136845 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Eslicarbazepine acetate is a is a once-daily antiepileptic drug (AED) that was approved in 2009 by the European Medicin… | Therapeutic advances in neurological disorders 2026-07-08 12:06:42 | Source |
| K7 and K Potassium Channels in Thalamocortical Function and Their The… Effects of Antiepileptic Drugs on Brain Excitability · PMID 42261627 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Potassium (K) channels are one of the key regulators of neuronal excitability and network stability. Among all the pota… | Archiv der Pharmazie 2026-07-08 12:06:42 | Source |
| Lateral Habenula 5-HT₂A Receptors Mediate Social Deficits in a Valpro… Effects of Antiepileptic Drugs on Brain Excitability · PMID 42277370 | Épilepsie | Traitement symptomatique | Publication | PubMed | Voir la publication source Autism Spectrum Disorder (ASD) is characterized by social deficits, yet underlying neural mechanisms remain poorly unde… | Molecular neurobiology 2026-07-08 12:06:42 | Source |
| Progress report on new antiepileptic drugs: a summary of the Ninth Ei… BIA 2-093 · PMID 19008076 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source The Ninth Eilat Conference on New Antiepileptic Drugs (AEDs)-EILAT IX, took place in Sitges, Barcelona from the 15th to… | Epilepsy research 2026-07-08 12:06:42 | Source |
| Diagnostic performance of [18F]FDG PET/CT in large vessel vasculitis… 18F-FDG · PMID 42411928 | Cancer · Épilepsie · Épilepsie | Immunomodulation | Publication | PubMed | Voir la publication source Large vessel vasculitis (LVV), encompassing giant cell arteritis (GCA), Takayasu arteritis (TAK) and polymyalgia rheuma… | The quarterly journal of nuclear medicine and molecula… 2026-07-08 12:06:41 | Source |
| Divergent Radiomolecular Phenotype of Spindle Cell Lipoma: Inten… 18F-FDG · PMID 42411770 | Cancer | À vérifier | Publication | PubMed | Voir la publication source A 68-year-old man with gastric cancer underwent 18F-fluorodeoxyglucose (FDG) PET/CT, which revealed an incidental subcu… | Clinical nuclear medicine 2026-07-08 12:06:41 | Source |
| Intermittent theta burst stimulation enhances the efficacy of brain-c… Intermittent theta burst stimulation · PMID 42404120 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source "BCI illiteracy," characterized by insufficient -rhythm Event-Related Desynchronization (ERD) in approximately 40% of s… | Frontiers in neurology 2026-07-08 12:06:40 | Source |
| Subchronic comparative assessment of graded ferrous sulfate doses on… 0.9% NaCl · PMID 42376110 | Maladie d’Alzheimer | Neuroprotection · Immunomodulation | Publication | PubMed | Voir la publication source Iron is a necessary trace element in the human body. However, excessive concentration can promote the overproduction of… | Open veterinary journal 2026-07-08 12:06:39 | Source |
| Sustainable soil improvement strategies for coral islands: Synergisti… 0.9% NaCl · PMID 42379437 | Maladie d’Alzheimer | À vérifier | Publication | PubMed | Voir la publication source The sustainable development of coral islands is constrained by bottleneck issues such as poor water retention and nutri… | International journal of biological macromolecules 2026-07-08 12:06:39 | Source |
| Minaxolone: an evaluation with and without premedication. Allopregnanolone injection (intravenous solution) · PMID 7270828 | Maladie d’Alzheimer | Traitement symptomatique | Publication | PubMed | Voir la publication source Minaxolone, a water-soluble steroid intravenous anaesthetic, has been used in clinical trials for induction and mainten… | Anaesthesia 2026-07-08 12:06:38 | Source |
| Continuous theta burst stimulation to the frontal pole durably decrea… Continuous theta burst stimulation · PMID 42379239 | Maladie de Parkinson | À vérifier | Publication | PubMed | Voir la publication source The frontal pole is a transdiagnostic target for affective disorders, perhaps through its connectivity with affective r… | International review of psychiatry (Abingdon, England) 2026-07-08 12:06:37 | Source |
| Role of the Upper Motor Neuron in the Generation of Fasciculations in… Continuous theta burst stimulation · PMID 42407013 | Sclérose latérale amyotrophique | À vérifier | Publication | PubMed | Voir la publication source The origin of fasciculation potentials (FPs) in the early stages of amyotrophic lateral sclerosis (ALS) remains a subje… | Neurology 2026-07-08 12:06:37 | Source |
| Extrapontine Myelinolysis and Reversible Parkinsonism After Hyponatre… Levodopa/carbidopa solution for SC administration · PMID 30055367 | Maladie de Parkinson | Traitement symptomatique | Publication | PubMed | Voir la publication source Osmotic demyelination syndrome commonly follows rapid correction of hyponatremia. Although pons is a common location, e… | World neurosurgery 2026-07-08 12:06:36 | Source |
| Foslevodopa/Foscarbidopa: A New Subcutaneous Treatment for Parkinson'… Levodopa/carbidopa solution for SC administration · PMID 33772855 | Maladie de Parkinson | À vérifier | Publication | PubMed | Voir la publication source The aim was to demonstrate that continuous s.c. infusion of a soluble levodopa (LD)/carbidopa (CD) phosphate prodrug co… | Annals of neurology 2026-07-08 12:06:36 | Source |
| Between Surgery and Science: Patient Journeys in Deep Brain Stimulati… Determining Patterns In Trial Experiences of Parkinson's Disease Patients · PMID 41910515 | Maladie de Parkinson | Thérapie génique | Publication | PubMed | Voir la publication source For the past 25 years, local field potential (LFP) recordings from externalized deep brain stimulation (DBS) leads have… | Neuromodulation : journal of the International Neuromo… 2026-07-08 12:06:35 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||