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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Treating Castleman disease: insights into the use and efficacy of mon… Rituximab · PMID 42423097 | Cancer · Lupus · Myasthénie · Sclérose en plaques · Myasthénie · Lupu… | Immunomodulation | Publication | PubMed | Voir la publication source Castleman disease (CD) is a rare, heterogeneous group of disorders driven by dysregulated cytokine signaling, particula… | Expert opinion on biological therapy 2026-07-10 00:23:41 | Source |
| [Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Depo… Rituximab · PMID 42423062 | Cancer · Lupus · Myasthénie · Sclérose en plaques · Myasthénie · Lupu… | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Monoclonal gammopathies of renal significance constitute a heterogeneous spectrum of nephropathies characterised by ren… | Giornale italiano di nefrologia : organo ufficiale del… 2026-07-10 00:23:41 | Source |
| Complement System Inhibitors in Nephrology: A Comprehensive Review. eculizumab · PMID 42423060 | Myasthénie · Sclérose en plaques · Myasthénie | Thérapie génique | Publication | PubMed | Voir la publication source The complement system plays a critical role in the pathogenesis of several kidney diseases. Dysregulation of complement… | Giornale italiano di nefrologia : organo ufficiale del… 2026-07-10 00:23:38 | Source |
| [Atypical hemolytic uremic syndrome: key points in differential diagn… eculizumab · PMID 42419994 | Myasthénie · Sclérose en plaques · Myasthénie | Thérapie génique | Publication | PubMed | Voir la publication source Atypical hemolytic uremic syndrome (aHUS) is a form of thrombotic microangiopathy (TMA) caused by endothelial injury re… | [Rinsho ketsueki] The Japanese journal of clinical hem… 2026-07-10 00:23:38 | Source |
| Commentary on: "Effect of inspiratory muscle training on inspiratory… Inspiratory muscle training · PMID 42421271 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Journal of rehabilitation medicine 2026-07-10 00:23:37 | Source |
| Effects of combined high-intensity inspiratory muscle training and ae… Inspiratory muscle training · PMID 42421207 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Inspiratory muscle training (ΙμΤ) with high loads, an adjuvant exercise modality in cardiac rehabilitation programs, se… | European journal of preventive cardiology 2026-07-10 00:23:37 | Source |
| Desipramine treatment disrupts phagocytic and intracellular survival… Desipramine · PMID 42211338 | Myopathies | Immunomodulation | Publication | PubMed | Voir la publication source abortus is an intracellular pathogen that causes chronic infection and remains difficult to treat. In this study, desip… | Frontiers in veterinary science 2026-07-10 00:23:35 | Source |
| The efficacy and safety of hyoscyamine, dicyclomine, and desipramine… Desipramine · PMID 42381757 | Myopathies | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Patients with ileal pouch-anal anastomosis (IPAA) frequently experience high bowel frequency and abdominal pain that ar… | Crohn's & colitis 360 2026-07-10 00:23:35 | Source |
| [Efficacy of electroacupuncture nerve stimulation therapy for interst… Gentamicin infusions twice a week for six months · PMID 31099215 | Myopathies | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source To explore the clinical efficacy of electroacupuncture nerve stimulation therapy (ENST) for interstitial cystitis/painf… | Zhongguo zhen jiu = Chinese acupuncture & moxibustion 2026-07-10 00:23:34 | Source |
| FDA-approved antisense oligonucleotide therapies for duchenne muscula… Casimersen · PMID 42324661 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Duchenne muscular dystrophy (DMD) is a fatal X-linked recessive disorder caused by dystrophin deficiency. Antisense oli… | RNA biology 2026-07-10 00:23:33 | Source |
| RNA Therapeutics Targeting Skeletal Muscle: Emerging Antisense and Ge… Casimersen · PMID 42352260 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source RNA-based therapeutics are reshaping the treatment landscape for skeletal muscle disorders by enabling modulation of RN… | Biomolecules 2026-07-10 00:23:33 | Source |
| Adjuvant intravenous immunoglobulin in elderly sepsis: a randomized c… IvIg · PMID 42422830 | Myopathies · Sclérose en plaques · Myopathies | Immunomodulation | Publication | PubMed | Voir la publication source Sepsis carries high mortality in older people, and immunomodulatory adjuncts to standard therapy are needed. To evaluat… | Frontiers in medicine 2026-07-10 00:23:32 | Source |
| Early postoperative onset of immune thrombocytopenia in rheumatoid ar… IvIg · PMID 42421261 | Lupus | À vérifier | Publication | PubMed | Voir la publication source Immune thrombocytopenia (ITP) is often already recognised as a pre-existing comorbidity before surgery and managed with… | Modern rheumatology case reports 2026-07-10 00:23:32 | Source |
| Gestational deltamethrin exposure exacerbates post-traumatic epilepti… Behavioral Interventions for Controlling Oral Behaviors · PMID 42384231 | Myopathies | Neuroprotection | Publication | PubMed | Voir la publication source Gestational exposure to the neurotoxic insecticide deltamethrin (DLT) is suspected to increase susceptibility to neurol… | Metabolic brain disease 2026-07-10 00:23:31 | Source |
| Global, regional, and national burden of tuberculosis and multidrug-r… Behavioral Interventions for Controlling Oral Behaviors · PMID 42385762 | Myopathies | Ralentissement de la progression | Publication | PubMed | Voir la publication source Tuberculosis (TB) is the leading global cause of death from a single infectious agent. Recent reductions in global heal… | The Lancet. Infectious diseases 2026-07-10 00:23:31 | Source |
| Free functional muscle transfer after oncologic extremity reconstruct… Functional muscle transfer · PMID 42206261 | Myopathies | Ralentissement de la progression | Publication | PubMed | Voir la publication source Limb-salvage surgery for extremity sarcoma increasingly prioritizes preservation of meaningful motor function, yet onco… | JPRAS open 2026-07-10 00:23:29 | Source |
| Structural and Functional Principles in Quadriceps Reconstruction. Functional muscle transfer · PMID 42347482 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Quadriceps muscle and tendon injuries are a significant cause of impairment of the knee extensor mechanism, ranging fro… | Muscles (Basel, Switzerland) 2026-07-10 00:23:29 | Source |
| Chronic pain after mastectomy: current knowledge and knowledge gaps. Capsaicin Topical Cream · PMID 41733557 | Cancer | Traitement symptomatique | Publication | PubMed | Voir la publication source Post-mastectomy pain syndrome (PMPS) is a frequent and burdensome complication of breast cancer surgery, manifesting as… | Minerva anestesiologica 2026-07-10 00:23:28 | Source |
| Non-Inferiority Study of Two Capsaicin Formulations for Painful Diabe… Capsaicin Topical Cream · PMID 41157180 | Myopathies | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source While capsaicin topical formulations are established treatments, conventional creams using this substance have limited… | Life (Basel, Switzerland) 2026-07-10 00:23:28 | Source |
| Acute Myocardial Infarction Secondary to Idiopathic Ascending Aortic… Revascularization · PMID 42423567 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Ascending aortic thrombus causing acute myocardial infarction through coronary ostial occlusion is exceptional, with on… | JACC. Case reports 2026-07-10 00:23:21 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||