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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Impact of Pre-operative Single-dose Methylprednisolone on Outcomes Af… Control Group · PMID 42437132 | Accident vasculaire cérébral · Myasthénie · Sclérose en plaques | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source The impact of a single preoperative steroid dose on inflammatory modulation and clinical outcomes in major hepatectomy… | Journal of clinical and experimental hepatology 2026-07-12 19:42:39 | Source |
| Phase I/II Study of NGGT001 Gene Therapy for Bietti Crystalline Dystr… GenPHSat injection (Safety) · PMID 42437119 | Myopathies | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source To evaluate the safety and preliminary functional outcomes of NGGT001 gene therapy across dose cohorts in adults with B… | Ophthalmology science 2026-07-12 19:42:37 | Source |
| Unregulated Peptide Use in the Age of Biohacking: Digital Promotion,… GenPHSat injection (Safety) · PMID 42437212 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Unregulated peptide use is emerging as a digitally mediated public health concern. Although peptide-based medicines hav… | Cureus 2026-07-12 19:42:37 | Source |
| Autologous adipose-derived mesenchymal stromal cells for chronic trau… HB-adMSCs · PMID 42093626 | Myopathies | Immunomodulation · Traitement symptomatique · Thérapie cellulaire | Publication | PubMed | Voir la publication source Secondary injury from traumatic brain injury (TBI) leads to a chronic inflammatory process, neurodegeneration, and tiss… | Brain : a journal of neurology 2026-07-12 19:42:36 | Source |
| Evaluation of Multiple Intravenous Infusions of Autologous Adipose-De… HB-adMSCs · PMID 42137372 | Maladie de Parkinson | Thérapie cellulaire | Publication | PubMed | Voir la publication source The purpose of this trial was to evaluate preliminary efficacy and safety of multiple intravenous infusions of autologo… | Parkinson's disease 2026-07-12 19:42:36 | Source |
| Genome-wide characterization of the Bcl-2-associated athanogene (BAG)… Glutamine · PMID 42435547 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Drought imposes one of the most damaging constraints on maize productivity, particularly during critical developmental… | Plant physiology and biochemistry : PPB 2026-07-12 19:42:36 | Source |
| How do media compositions, pretreatments, and genotypes affect haploi… Glutamine · PMID 42436375 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Currently, consumer demands are rapidly and continuously evolving, which accelerates the development and release of new… | BMC plant biology 2026-07-12 19:42:36 | Source |
| An 8-Year-Old Boy With Lateral Cutaneous Nerve Entrapment Syndrome: A… trigger point injection · PMID 42345584 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Pediatrics international : official journal of the Jap… 2026-07-12 19:42:33 | Source |
| Evaluation of Two Treatment Options in Myofascial Pain Transcutaneous… trigger point injection · PMID 42411416 | Myopathies | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Myofascial pain syndrome (MPS) is a familiar musculoskeletal disorder regarded as trigger points causing pain and funct… | Annals of African medicine 2026-07-12 19:42:33 | Source |
| Influence of Dystrophin Isoform Deficiency on Motor Development in Du… Outcome Measures in Duchenne Muscular Dystrophy: A Natural History Study · PMID 40552660 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source In Duchenne muscular dystrophy (DMD), lack of the shorter dystrophin isoforms Dp140 and Dp71 is associated with increas… | Annals of clinical and translational neurology 2026-07-12 19:42:33 | Source |
| Fulminant toxic epidermal necrolysis induced by pucotenlimab in a pat… IvIg · PMID 42434740 | Myopathies · Sclérose en plaques · Myopathies | Immunomodulation | Publication | PubMed | Voir la publication source This case report describes a fatal case of toxic epidermal necrolysis (TEN) in a 67-year-old man with stage IIIB lung a… | Frontiers in oncology 2026-07-12 19:42:28 | Source |
| Guillain-Barré Syndrome Following Dengue Infection: A Case Series wit… IvIg · PMID 42436651 | Accident vasculaire cérébral | Neuroprotection · Ralentissement de la progression · Immunomodulation | Publication | PubMed | Voir la publication source Guillain-Barré syndrome (GBS) is a rare, immune-mediated disorder of the peripheral nerve and roots often triggered by… | Annals of neurosciences 2026-07-12 19:42:28 | Source |
| Nurse-led tobacco and areca-nut cessation interventions for oral pote… Behavioral Interventions for Controlling Oral Behaviors · PMID 42426750 | Cancer | Ralentissement de la progression · Thérapie génique | Publication | PubMed | Voir la publication source Oral potentially malignant disorders (OPMDs), including oral submucous fibrosis, leukoplakia, lichen planus, and erythr… | BMC oral health 2026-07-12 19:42:28 | Source |
| Analyzing the Effect of Extracorporeal Shockwave Therapy after Botuli… Botulinum Toxin Type A for Injection · PMID 42427431 | Sclérose en plaques | Traitement symptomatique | Publication | PubMed | Voir la publication source Spasticity is a frequent and disabling manifestation of multiple sclerosis (MS), characterized by increased muscle tone… | Advanced biomedical research 2026-07-12 19:42:26 | Source |
| Cellular Remodeling of Skeletal Muscle Following Botulinum Toxin A In… Botulinum Toxin Type A for Injection · PMID 42432377 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Botulinum toxin type A (BoNT) is widely used in aesthetic and reconstructive surgery, yet its effects on skeletal muscl… | Aesthetic plastic surgery 2026-07-12 19:42:26 | Source |
| A double-blinded randomized clinical trial: Topical Sahasthara extrac… Diclofenac 1% Topical · PMID 42382062 | Myopathies | Immunomodulation · Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Sahasthara (SHT), a traditional Thai herbal remedy used for anti-inflammatory and musculoskeletal disorders, lacks clin… | Journal of traditional and complementary medicine 2026-07-12 19:42:25 | Source |
| Baboon Syndrome Triggered by Diclofenac Potassium: A Case Report of S… Diclofenac 1% Topical · PMID 42405225 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Baboon syndrome, also known as symmetrical drug-related intertriginous and flexural exanthema (SDRIFE), is a rare react… | Case reports in dermatology 2026-07-12 19:42:25 | Source |
| Risk factors of multi-drug-resistant tuberculosis among tuberculosis… COVID-19 Pandemic and Parents of Disabled Children · PMID 42426652 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Drug-resistant tuberculosis poses a significant threat to global TB control efforts, potentially reversing progress mad… | BMC infectious diseases 2026-07-12 19:42:15 | Source |
| A comparison of conservative versus surgical treatment in patients wi… test of walk · PMID 42436915 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Patients with foot drop due to peroneal nerve entrapment are treated with either conservative or surgical approaches, y… | Brain & spine 2026-07-12 19:42:13 | Source |
| Multimodal Integration of Gait, Balance, and Infrared Thermography En… test of walk · PMID 42435928 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source To investigate whether combining gait, balance, and infrared thermography improves discrimination between individuals w… | Archives of physical medicine and rehabilitation 2026-07-12 19:42:13 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||