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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| RAS signaling at the crossroads of radioresistance and tumor immunity. radiation therapy · PMID 42468991 | Cancer | À vérifier | Publication | PubMed | Voir la publication source RAS mutations are among the most prevalent oncogenic drivers in solid tumors and are consistently associated with subop… | Journal for immunotherapy of cancer 2026-07-18 15:46:46 | Source |
| Clinicopathological and molecular characteristics of primary pulmonar… paclitaxel albumin-stabilized nanoparticle formulation · PMID 42453887 | Cancer | Ralentissement de la progression | Publication | PubMed | Voir la publication source Primary pulmonary choriocarcinoma (PPC) is an exceptionally rare and aggressive non-gestational trophoblastic malignanc… | Frontiers in oncology 2026-07-18 15:46:45 | Source |
| Treatment Sequencing in Platinum-Resistant Epithelial Ovarian Cancer… paclitaxel albumin-stabilized nanoparticle formulation · PMID 42453787 | Cancer | Ralentissement de la progression | Publication | PubMed | Voir la publication source Platinum-resistant epithelial ovarian cancer has long been managed as a clinically defined state with limited therapeut… | International journal of women's health 2026-07-18 15:46:45 | Source |
| Facial solitary morphea profunda presenting with painful trigeminal n… eslicarbacepine · PMID 30213201 | Épilepsie | Traitement symptomatique | Publication | PubMed | Voir la publication source Localized facial scleroderma usually presents as frontal linear morphea or progressive hemifacial atrophy. Only isolate… | Cephalalgia : an international journal of headache 2026-07-18 15:46:43 | Source |
| Effects of concurrent transcranial direct current stimulation on huma… Transcranial Direct Current Stimulation (TDCS) · PMID 42463027 | Épilepsie · Maladie de Parkinson · Épilepsie · Maladie de Parkinson | À vérifier | Publication | PubMed | Voir la publication source Motor learning is important throughout the human lifespan for the acquisition, refinement, and preservation of motor sk… | Behavioural brain research 2026-07-18 15:46:42 | Source |
| From State to Trait: A Narrative Review Refining Our Understanding of… Neurosurgical Outcome Network · PMID 42466737 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Preoperative anxiety is common in patients undergoing neurosurgical procedures and is known to influence the perioperat… | Journal of neurosurgical anesthesiology 2026-07-18 15:46:36 | Source |
| Risk of immediate and delayed intracranial hemorrhage after minor hea… Neurosurgical Outcome Network · PMID 42468197 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Minor head trauma frequently prompts emergency department (ED) evaluation and raises concern for intracranial hemorrhag… | The American journal of emergency medicine 2026-07-18 15:46:36 | Source |
| Antiseizure medication dosing and monitoring in the intensive care un… Brivaracetam (ucb34714) · PMID 42455344 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Antiseizure medications (ASMs) are commonly used in the intensive care unit (ICU) and often exhibit pharmacokinetics th… | Intensive care medicine 2026-07-18 15:46:32 | Source |
| Trends in antiseizure medication use among women of childbearing age… Brivaracetam (ucb34714) · PMID 42468160 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Women of childbearing age (WOCBA) with epilepsy who have significant adverse events or fail to achieve seizure freedom… | Journal of the neurological sciences 2026-07-18 15:46:32 | Source |
| BRASH Syndrome Unmasked: Digoxin Toxicity in the Setting of Cardiogen… Digoxin · PMID 42460411 | Insuffisance cardiaque | Traitement symptomatique | Publication | PubMed | Voir la publication source Digoxin, a cardiac glycoside historically used for rate control in atrial arrhythmias and symptom relief in chronic hea… | Case reports in critical care 2026-07-18 15:46:28 | Source |
| Ivabradine in refractory neonatal ectopic atrial tachycardia: expandi… Digoxin · PMID 42466720 | Épilepsie · Sclérose latérale amyotrophique · Sclérose latérale amyot… | À vérifier | Publication | PubMed | Voir la publication source Neonatal ectopic atrial tachycardia is a rare arrhythmia that may be resistant to conventional therapy. We report a neo… | Cardiology in the young 2026-07-18 15:46:28 | Source |
| Age-dependent effects of cannabidiol on cortical hyperexcitability in… Effects of Antiepileptic Drugs on Brain Excitability · PMID 42331276 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Malformations of cortical development (MCD) are major causes of refractory epilepsies, particularly in children. Cannab… | Experimental neurology 2026-07-18 15:46:27 | Source |
| FDG-PET in Traumatic Brain Injury and Postconcussive Sequelae. 18F-FDG · PMID 42469060 | Cancer · Épilepsie · Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Traumatic brain injury (TBI) produces complex and evolving metabolic disturbances that are not fully captured by struct… | PET clinics 2026-07-18 15:46:25 | Source |
| PET/CT Normal Variants and Pitfalls in Paediatric Disorders. 18F-FDG · PMID 42469126 | Cancer · Épilepsie · Épilepsie | Immunomodulation | Publication | PubMed | Voir la publication source 18F- Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (18F-FDG PET/CT) has become an indispensable i… | Seminars in nuclear medicine 2026-07-18 15:46:25 | Source |
| Circular eight-room maze for assessing spatial learning and memory fu… Sham LIT · PMID 39276609 | Maladie d’Alzheimer | À vérifier | Publication | PubMed | Voir la publication source This study introduced an animal cognitive function assessment system using a novel circular eight-room maze (CERM). The… | Computers in biology and medicine 2026-07-18 15:46:23 | Source |
| Liver antifibrosis mechanisms of oligomeric grape seed proanthocyanid… Sham LIT · PMID 41910701 | Maladie d’Alzheimer | Immunomodulation | Publication | PubMed | Voir la publication source Bile duct ligation (BDL) induces liver fibrosis, representing a significant clinical challenge. Oligomeric grape seed p… | Inflammopharmacology 2026-07-18 15:46:23 | Source |
| Comparative analgesic outcomes of anterior quadratus lumborum block a… Lighting Intervention Therapy · PMID 42470031 | Maladie d’Alzheimer | Traitement symptomatique | Publication | PubMed | Voir la publication source Pain following laparoscopic cholecystectomy often necessitates substantial opioid use. This study aimed to compare post… | Medicine 2026-07-18 15:46:22 | Source |
| Is inpatient monitoring necessary in pediatric patients with comorbid… Lighting Intervention Therapy · PMID 42469506 | Maladie d’Alzheimer | À vérifier | Publication | PubMed | Voir la publication source Children and young adults with severe pre-existing conditions frequently require dental treatment under general anesthe… | Oral and maxillofacial surgery 2026-07-18 15:46:22 | Source |
| 36th International Symposium on Intensive Care and Emergency Medicine… VALID — Volunteers Adding Life in Dementia · PMID 27885969 | Hypertension artérielle · Insuffisance cardiaque · Maladie coronarien… | Neuroprotection · Ralentissement de la progression · Immunomodulation · Traitem… | Publication | PubMed | Voir la publication source P001 - Sepsis impairs the capillary response within hypoxic capillaries and decreases erythrocyte oxygen-dependent ATP… | Critical care (London, England) 2026-07-18 15:46:21 | Source |
| The role of perseverance on the association between resilience and su… Couples Coping With Alzheimer's Disease · PMID 42455702 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Although resilience and perseverance are known for their physical health benefits, evidence on their effects on cogniti… | Journal of psychosocial oncology 2026-07-18 15:46:09 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||