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Toutes les maladies
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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Feasibility of Real-Time Autonomous Functional Electrical Stimulation… test of walk · PMID 42484421 | Maladie de Parkinson | Traitement symptomatique | Publication | PubMed | Voir la publication source Freezing of gait is a debilitating walking disturbance that can severely worsen quality of life for people with Parkins… | The European journal of neuroscience 2026-07-22 21:22:37 | Source |
| Persistent hiccups following endobronchial ultrasound-guided transbro… baclofen · PMID 42471910 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive diagnostic procedu… | Respiratory medicine case reports 2026-07-22 21:22:33 | Source |
| Six approved drugs for alcohol use disorder: algorithms for their use… baclofen · PMID 42476146 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source The pharmacological management of alcohol use disorder (AUD) currently includes six medications approved by different r… | Alcohol and alcoholism (Oxford, Oxfordshire) 2026-07-22 21:22:33 | Source |
| Accelerated recovery and alleviated pain by oral whey protein in herp… standard therapy · PMID 42482061 | Lupus | Neuroprotection · Traitement symptomatique | Publication | PubMed | Voir la publication source Herpes zoster is usually caused by varicella-zoster virus reactivation, particularly in the aged. It imposes postherpet… | Nutrition journal 2026-07-22 21:22:26 | Source |
| Successful Trifarotene Treatment of a Typical Kyrle's Disease With Ov… standard therapy · PMID 42480558 | Lupus | Immunomodulation | Publication | PubMed | Voir la publication source Kyrle's disease is a rare skin disorder involving transepidermal keratin elimination, usually linked to systemic illnes… | Skin research and technology : official journal of Int… 2026-07-22 21:22:26 | Source |
| Atorvastatin-associated neurological adverse events: a disproportiona… Atorvastatin · PMID 42482918 | Maladie coronarienne | Neuroprotection | Publication | PubMed | Voir la publication source Atorvastatin, a widely prescribed HMG-CoA reductase inhibitor, is associated with neurological adverse events (NAEs) be… | Frontiers in medicine 2026-07-22 21:22:20 | Source |
| Derived inflammatory indicators for identifying preeclampsia in pregn… Assessment of Blood Indices in Systemic Lupus Erythematosus · PMID 42481938 | Lupus | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Pregnant women with systemic lupus erythematosus (SLE) are at high risk of preeclampsia (PE). However, overlapping clin… | BMC pregnancy and childbirth 2026-07-22 21:22:19 | Source |
| A WO@Bi-BiVO based Z-scheme heterojunction for photoelectrochemical s… Anti-CD19-CD3E-CAR-T cells · PMID 42485065 | Lupus | Remyélinisation indirecte / réparation · Neuroprotection · Thérapie cellulaire | Publication | PubMed | Voir la publication source Batatasin (a natural antioxidant ingredient) is expected to have an effect on the release of reactive oxygen species fr… | Chemical communications (Cambridge, England) 2026-07-22 21:22:17 | Source |
| Exosome-Loaded Zinc Sulfide Nanoparticles Therapy for Psoriasis: Immu… Anti-CD19-CD3E-CAR-T cells · PMID 42485082 | Lupus | Immunomodulation · Traitement symptomatique · Thérapie cellulaire | Publication | PubMed | Voir la publication source This study investigates the therapeutic efficacy of zinc sulfide nanoparticles (ZnS NPs) encapsulated within adipose-de… | Journal of drug targeting 2026-07-22 21:22:17 | Source |
| From Molecular Pathophysiology to Clinical Trial Design in Sjögren's… Ianalumab · PMID 42449965 | Lupus | Traitement symptomatique | Publication | PubMed | Voir la publication source Sjögren's disease (SjD) remains one of the few major systemic autoimmune diseases without an approved disease-modifying… | International journal of molecular sciences 2026-07-22 21:22:16 | Source |
| Case Report: Severe ANCA-positive eosinophilic granulomatosis with po… Rituximab · PMID 42483201 | Cancer · Lupus · Myasthénie · Sclérose en plaques · Myasthénie · Lupu… | Immunomodulation | Publication | PubMed | Voir la publication source Eosinophilic granulomatosis with polyangiitis (EGPA) is an anti-neutrophil cytoplasmic antibody (ANCA)-associated syste… | Frontiers in immunology 2026-07-22 21:22:10 | Source |
| Post-transplant lymphoproliferative disorder after solid organ transp… Rituximab · PMID 42483433 | Cancer · Lupus · Myasthénie · Sclérose en plaques · Myasthénie · Lupu… | Immunomodulation · Thérapie cellulaire | Publication | PubMed | Voir la publication source Post-transplant lymphoproliferative disorder (PTLD) is a serious and heterogeneous neoplastic complication of solid org… | Frontiers in transplantation 2026-07-22 21:22:10 | Source |
| Armed Oncolytic Myxoma Virus Induces Systemic Antitumor Immunity Agai… ET1402L1-ARTEMIS™ T cells -Intratumoral Injections · PMID 42466427 | Cancer | Immunomodulation | Publication | PubMed | Voir la publication source Oncolytic viruses expressing immunostimulatory transgenes can enhance immune cells recruitment into the tumor bed and a… | Research square 2026-07-22 21:22:03 | Source |
| The closer, the better: intratumoral delivery of a thermoresponsive g… ET1402L1-ARTEMIS™ T cells -Intratumoral Injections · PMID 42471543 | Cancer | Immunomodulation | Publication | PubMed | Voir la publication source Current treatments for pancreatic ductal adenocarcinoma (PDAC) patients are typically restricted to (neo)adjuvant chemo… | Drug delivery and translational research 2026-07-22 21:22:03 | Source |
| In situ delivery of allogeneic natural killer cell (NK) combined with… ET1402L1-ARTEMIS™ T cells -intra-hepatic artery · PMID 29721386 | Cancer | Immunomodulation | Publication | PubMed | Voir la publication source Despite successful introduction of NK-based cellular therapy in the treatment of myeloid leukemia, the potential use of… | Oncoimmunology 2026-07-22 21:22:02 | Source |
| [Selective effectiveness of galactose-containing liposome IL-2 on liv… ET1402L1-ARTEMIS™ T cells -intra-hepatic artery · PMID 7944413 | Cancer | Immunomodulation | Publication | PubMed | Voir la publication source We have performed immunochemical intraarterial infusion immunochemotherapy containing IL-2, mitomycin C and 5-FU as the… | Gan to kagaku ryoho. Cancer & chemotherapy 2026-07-22 21:22:02 | Source |
| Apatinib enhances targeted immunotherapy the IL-6-gp130-PI3K pathway… ET1402L1-ARTEMIS™ T cells -IV · PMID 42478052 | Cancer | Immunomodulation · Thérapie cellulaire · Thérapie génique | Publication | PubMed | Voir la publication source We aimed to evaluate chemotherapy-free apatinib-based immunotherapy regimens for patients with human epidermal growth f… | Cancer biology & medicine 2026-07-22 21:22:01 | Source |
| FGFR2 fusion-driven cholangiocarcinoma is characterized by a distinct… ET1402L1-ARTEMIS™ T cells -IV · PMID 42480814 | Cancer | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Fibroblast growth factor receptor 2 gene (FGFR2) rearrangements are among the most common oncogenic drivers in intrahep… | JHEP reports : innovation in hepatology 2026-07-22 21:22:01 | Source |
| Effects of TNF-α, IL-1β and IL-2 on regulatory T cells in children wi… IL-2 · PMID 42483409 | Cancer | Immunomodulation | Publication | PubMed | Voir la publication source The pathogenesis of idiopathic nephrotic syndrome (INS) is unknown, but previous studies suggested that alterations of… | Frontiers in pediatrics 2026-07-22 21:22:00 | Source |
| Tumor-infiltrating lymphocyte (TIL) therapy: Historical context, clin… IL-2 · PMID 42482408 | Cancer | Immunomodulation | Publication | PubMed | Voir la publication source In the past 15 years, immunotherapy has become a major strategy for cancer therapy. Tumor-infiltrating lymphocyte (TIL)… | Cancer 2026-07-22 21:22:00 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||