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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Carbonic anhydrase VII: Development of selective inhibitors and their… Effects of Antiepileptic Drugs on Brain Excitability · PMID 42486546 | Épilepsie | Neuroprotection | Publication | PubMed | Voir la publication source Human carbonic anhydrase VII (hCA VII) is a cytosolic zinc metalloenzyme largely expressed in the brain, where it plays… | The Enzymes 2026-07-23 12:25:21 | Source |
| How Many Days Do We Need? Defining Reliable ActivPAL Monitoring Proto… ActivPAL · PMID 42436015 | Maladie d’Alzheimer | À vérifier | Publication | PubMed | Voir la publication source Although device-measured data provide more reliable estimates of movement behaviors than self-report questionnaires, de… | Scandinavian journal of medicine & science in sports 2026-07-23 12:25:20 | Source |
| Performance Evaluation of Device-Based Algorithms to Estimate Step Co… ActivPAL · PMID 42456002 | Maladie d’Alzheimer | À vérifier | Publication | PubMed | Voir la publication source Step counts are a widely used indicator of activity in studies of physical activity and health, but direct evidence of… | Medicine and science in sports and exercise 2026-07-23 12:25:20 | Source |
| Detecting amyloid-β pathology in subjective cognitive decline using p… PLASM-ALZ — Diagnostic Performance of Plasma Biomarkers of Alzheimer's Disease Compared With C… | Maladie d’Alzheimer | À vérifier | Publication | PubMed | Voir la publication source Subjective cognitive decline (SCD) may represent an early stage of Alzheimer's disease (AD), but biomarker studies in t… | EBioMedicine 2026-07-23 12:25:17 | Source |
| Diagnostic performance of plasma p-Tau217, p-Tau181, and p-Tau231 acr… PLASM-ALZ — Diagnostic Performance of Plasma Biomarkers of Alzheimer's Disease Compared With C… | Maladie d’Alzheimer | Ralentissement de la progression | Publication | PubMed | Voir la publication source Blood-based biomarkers (BBMs) are transforming the diagnostic workflow for Alzheimer's disease (AD). However, there is… | Frontiers in aging neuroscience 2026-07-23 12:25:17 | Source |
| Food resources and kitchen skills plus aerobic training (FoRKS+) for… Effects of Multicomponent Physical Exercise Program and Mediterranean Diet in Alzheimer's Dise… | Hypertension artérielle · Maladie d’Alzheimer | À vérifier | Publication | PubMed | Voir la publication source Midlife hypertension is associated with cognitive decline and Alzheimer's disease and related dementia (ADRD), suggesti… | Contemporary clinical trials 2026-07-23 12:25:16 | Source |
| Short and medium-term effects of a multicomponent physical exercise p… Effects of Multicomponent Physical Exercise Program and Mediterranean Diet in Alzheimer's Dise… | Maladie d’Alzheimer | Ralentissement de la progression · Thérapie génique | Publication | PubMed | Voir la publication source Reduced bone mineral density and increased risk of falls are related with Alzheimer disease, and these increase likelih… | Medicine 2026-07-23 12:25:16 | Source |
| Comparative efficacy and safety of photobiomodulation, transcranial d… Lighting Intervention Therapy · PMID 42487022 | Maladie d’Alzheimer | À vérifier | Publication | PubMed | Voir la publication source Alzheimer's disease (AD) is a progressive neurodegenerative disorder for which current pharmacological therapies provid… | Lasers in medical science 2026-07-23 12:25:14 | Source |
| Sedation, Analgesia, and Neuromuscular Blockade. Lighting Intervention Therapy · PMID 42486557 | Maladie d’Alzheimer | À vérifier | Publication | PubMed | Voir la publication source Optimal sedation and analgesia in critical illness require a structured, patient-centered approach grounded in an under… | Clinics in chest medicine 2026-07-23 12:25:14 | Source |
| In vivo tolerability of topical telavancin versus vancomycin in a mur… 0.9% NaCl · PMID 42483981 | Maladie d’Alzheimer | À vérifier | Publication | PubMed | Voir la publication source Multicentre surveillance studies show increasing resistance among ocular MDR bacteria causing sight-threatening infecti… | The Journal of antimicrobial chemotherapy 2026-07-23 12:25:01 | Source |
| Therapeutic potential of flavonoids and rutin against inflammation-in… 0.9% NaCl · PMID 42461930 | Maladie d’Alzheimer | Neuroprotection · Immunomodulation | Publication | PubMed | Voir la publication source This study tested the hypothesis that flavonoids (diosmine, hesperidin and rutin®) play a protective role in the brain… | PloS one 2026-07-23 12:25:01 | Source |
| Bodily intolerance of uncertainty influences perceptual recalibration… Intervention with virtual reality · PMID 42485914 | Maladie de Parkinson | À vérifier | Publication | PubMed | Voir la publication source Perception of our own body can dynamically change based on precision weighting of sensory prediction errors. The curren… | Consciousness and cognition 2026-07-23 12:24:56 | Source |
| [Ophthalmological surgery simulation: an interim assessment after 3 y… Intervention with virtual reality · PMID 42484853 | Maladie de Parkinson | À vérifier | Publication | PubMed | Voir la publication source Simulator-based medical education (SBME) is increasingly being used as an effective method for teaching surgical skills… | Die Ophthalmologie 2026-07-23 12:24:56 | Source |
| Enhanced home-based transcranial direct-current stimulation (tDCS) fo… Sham tDCS · PMID 42476741 | Maladie de Parkinson · Sclérose en plaques · Maladie de Parkinson | Traitement symptomatique | Publication | PubMed | Voir la publication source Major depressive disorder (MDD) is the most common comorbidity among individuals with borderline personality disorder (… | BMJ open 2026-07-23 12:24:51 | Source |
| Improved visual perception through visuomotor-coupled brain stimulati… Sham tDCS · PMID 42456796 | Maladie de Parkinson · Sclérose en plaques · Maladie de Parkinson | À vérifier | Publication | PubMed | Voir la publication source Non-invasive brain stimulation (NIBS) allows to investigate the causal relationship between the activity of a target br… | NeuroImage 2026-07-23 12:24:51 | Source |
| Observational study of central venous catheter placement in children… Platelet transfusion · PMID 42485173 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source * outline the findings of a study undertaken at Hedi Chaker University Hospital, Sfax, Tunisia, on infraclavicular cent… | British journal of nursing (Mark Allen Publishing) 2026-07-23 12:24:33 | Source |
| Evaluation of the humoral response during ocrelizumab therapy in mult… Ocrelizumab · PMID 42478450 | Sclérose en plaques | Immunomodulation | Publication | PubMed | Voir la publication source Anti-CD20 monoclonal antibodies are widely used as high-efficacy treatment agents (HETAs) in multiple sclerosis (MS). I… | Neurologia i neurochirurgia polska 2026-07-23 12:24:22 | Source |
| Ocrelizumab-induced colitis acutely managed with ciclosporin. Ocrelizumab · PMID 42486658 | Sclérose en plaques | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Ocrelizumab is an anti-CD20 monoclonal antibody widely used in the treatment of multiple sclerosis (MS). Although rare,… | BMJ case reports 2026-07-23 12:24:22 | Source |
| Targeting progressive multiple sclerosis: Toward mechanism-informed p… Risk Factors in Early Multiple Sclerosis · PMID 42482223 | Sclérose en plaques | Remyélinisation · Ralentissement de la progression · Immunomodulation | Publication | PubMed | Voir la publication source Multiple sclerosis has undergone a therapeutic revolution over the past three decades. Randomized clinical trials and r… | Journal of internal medicine 2026-07-23 12:24:12 | Source |
| ZnGeO:Mn Luminescent Superparticles/Au-Ag Bimetallic Nanoarrays for E… Ginseng · PMID 42485233 | Sclérose en plaques | Thérapie génique | Publication | PubMed | Voir la publication source MicroRNA (miRNA) in plant exosomes exhibits cross-species regulatory properties, opening a new avenue for researching n… | Analytical chemistry 2026-07-23 12:24:10 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||