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Périmètre
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Chaque choix s’applique immédiatement aux quatre sections. Le filtre « type de SEP » n’apparaît que lorsque la sclérose en plaques est sélectionnée.
10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| User Acceptance of a Virtual Reality Beer Pong Intervention in Postop… Early Highly Effective Therapies Group · PMID 42565056 | Sclérose en plaques | Traitement symptomatique | Publication | PubMed | Voir la publication source Postoperative patients often face pain, reduced mobility, and motivational barriers, while health care systems increasi… | JMIR XR and spatial computing 2026-08-08 00:55:47 | Source |
| Evaluating the efficacy and safety of transitioning patients with mul… OCTAVE — Evaluating the Efficacy and Safety of Transitioning Patients From Natalizumab to Ocre… | Sclérose en plaques | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Natalizumab is associated with a risk of progressive multifocal leukoencephalopathy (PML) in multiple sclerosis (MS) pa… | Multiple sclerosis (Houndmills, Basingstoke, England) 2026-08-08 00:55:46 | Source |
| Ambulatory Neuroproprioceptive Facilitation and Inhibition Physical T… Physical Therapy and Neuroactive Steroids Therapy Does Not Modulate Serum Level of Neuroactive… | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source Background Only few studies have monitored the potential of physical activity training and physical therapy to modulate… | Life (Basel, Switzerland) 2026-08-08 00:55:44 | Source |
| Peptide profiling of Internet-obtained Cerebrolysin using high perfor… Trap Myelin Test · PMID 26017115 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source Cerebrolysin, a parenteral peptide preparation produced by controlled digestion of porcine brain proteins, is an approv… | Drug testing and analysis 2026-08-08 00:55:44 | Source |
| Reversing the Tumor Target: Establishment of a Tumor Trap. Trap Myelin Test · PMID 31456685 | Cancer | Thérapie génique | Publication | PubMed | Voir la publication source Despite the tremendous progress made in the field of cancer therapy in recent years, certain solid tumors still cannot… | Frontiers in pharmacology 2026-08-08 00:55:44 | Source |
| The effect of moderate-intensity aerobic training on pulmonary functi… Physical Therapy and Neuroactive Steroids Therapy Does Not Modulate Serum Level of Neuroactive… | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source The impact of aerobic training on pulmonary function by modulating gene expression of estrogen receptor-alpha (ERα), se… | Respiratory physiology & neurobiology 2026-08-08 00:55:44 | Source |
| Real-world COVID-19 immunity in multiple sclerosis (CoVaR-MS): A long… CoVaR-MS — Covid-19 Vaccine Immune Response in Multiple Sclerosis · PMID 41518821 | Sclérose en plaques | Immunomodulation | Publication | PubMed | Voir la publication source COVID-19 vaccination in Multiple Sclerosis (MS) has continued clinical relevance. Complex dosing and variability in imm… | Multiple sclerosis and related disorders 2026-08-08 00:55:41 | Source |
| Medical cannabis improved self-reported spasticity rating in patients… Other treatment · PMID 42544174 | Sclérose en plaques | Traitement symptomatique | Publication | PubMed | Voir la publication source Previous studies demonstrated that cannabinoids may reduce spasticity in patients with spinal cord injury (SCI); howeve… | Therapeutic advances in neurological disorders 2026-08-08 00:55:40 | Source |
| Preferences for Smartphone Versus In-Person Delivery of Contingency M… Other treatment · PMID 42551922 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source Smartphone delivery of contingency management (CM) could overcome barriers to dissemination of this effective treatment… | Drug and alcohol review 2026-08-08 00:55:40 | Source |
| Early treatment with ofatumumab increases the likelihood of stabilizi… monoclonal CD-20 antibodies · PMID 42312094 | Sclérose en plaques | Ralentissement de la progression | Publication | PubMed | Voir la publication source Methods of multiple sclerosis (MS) treatment are evolving rapidly, with numerous classes of disease-modifying therapies… | Archives of medical science : AMS 2026-08-08 00:55:39 | Source |
| Ersodetug for Refractory Hypoglycemia Due to Malignant Insulin-Secret… No Drug · PMID 42557582 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source Refractory hypoglycemia is common in malignant insulin-secreting tumors and is associated with substantial morbidity. E… | The Journal of clinical endocrinology and metabolism 2026-08-08 00:55:39 | Source |
| Evaluation of the Safety and Efficacy of SOF/VEL Treatment and Pre-tr… No Drug · PMID 42558970 | Sclérose en plaques | Thérapie génique | Publication | PubMed | Voir la publication source Hepatitis B virus (HBV) infection and hepatitis C virus (HCV) infection are among the leading causes of chronic liver d… | Journal of clinical and translational hepatology 2026-08-08 00:55:39 | Source |
| Coin rotation task: a valid test for manual dexterity in multiple scl… Study to Evaluate the Reliability and Validity of the Modified Manual Muscle Test for Persons… | Sclérose en plaques | Ralentissement de la progression | Publication | PubMed | Voir la publication source Impaired manual dexterity is frequent and disabling in people with multiple sclerosis (MS). Therefore, convenient, quic… | Physical therapy 2026-08-08 00:55:37 | Source |
| Quantitative Ultrasound Imaging to Assess Skeletal Muscles in Adults… Study to Evaluate the Reliability and Validity of the Modified Manual Muscle Test for Persons… | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source The aim of this study was to assess the feasibility of quantitative ultrasound imaging (QUI) in assessing the biceps br… | Journal of ultrasound in medicine : official journal o… 2026-08-08 00:55:37 | Source |
| Clinical efficacy, safety and applicability of home-based bright ligh… dim red light · PMID 42150833 | Sclérose en plaques | Ralentissement de la progression · Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Major depressive disorder (MDD) is a leading cause of disability among adolescents, yet available treatments remain lim… | BMJ open 2026-08-08 00:55:36 | Source |
| Exploratory crossover field study indicates efficacy and feasibility… dim red light · PMID 42336901 | Sclérose en plaques | Traitement symptomatique | Publication | PubMed | Voir la publication source Fatigue is highly prevalent, clinically significant, and persistent in multiple sclerosis (MS), highlighting the need f… | Scientific reports 2026-08-08 00:55:36 | Source |
| Examining the Effects of Bright Light Therapy on Sleep and Resting-St… bright light therapy · PMID 42549269 | Maladie de Parkinson | À vérifier | Publication | PubMed | Voir la publication source Sleep disturbances are highly prevalent in patients with Parkinson's disease (PD). Bright light therapy (BLT) seems to… | Nature and science of sleep 2026-08-08 00:55:35 | Source |
| Light therapy in medicine: where do we stand? bright light therapy · PMID 42434781 | Sclérose en plaques | Remyélinisation indirecte / réparation · Traitement symptomatique | Publication | PubMed | Voir la publication source Light therapy encompasses a broad spectrum of interventions, ranging from established clinical applications to emerging… | Annals of translational medicine 2026-08-08 00:55:35 | Source |
| Lymphoplasmapheresis for Refractory Anti-N-Methyl-D-Aspartate Recepto… Ofatumumab · PMID 42503002 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is generally responsive to immunotherapy, but some patients rem… | Journal of clinical apheresis 2026-08-08 00:55:33 | Source |
| Possible Contribution of Multiple Sclerosis Pathology to Treatment-Re… Ofatumumab · PMID 42559701 | Sclérose en plaques | Traitement symptomatique | Publication | PubMed | Voir la publication source Multiple sclerosis (MS) can present with neurological and psychiatric symptoms that may overlap with those of schizophr… | Neuropsychopharmacology reports 2026-08-08 00:55:33 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||