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Périmètre
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Physiologic Adaptations to Modifying Resistive Load and Time Under Te… EMST · PMID 42531563 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source The purpose of this study was to test the impact of modifying resistive load and time under tension (TUT) on respirator… | Journal of speech, language, and hearing research : JS… 2026-08-08 00:55:58 | Source |
| Effects of respiratory muscle training on respiratory function, exerc… Inspiratory Muscle Training in Individuals With Multiple Sclerosis · PMID 41678965 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source This systematic review and meta-analysis aimed to evaluate the effects of respiratory muscle training (RMT) on respirat… | Multiple sclerosis and related disorders 2026-08-08 00:55:57 | Source |
| Effects of respiratory muscle training on respiratory function, trunk… Inspiratory Muscle Training in Individuals With Multiple Sclerosis · PMID 41981242 | Sclérose en plaques | Traitement symptomatique | Publication | PubMed | Voir la publication source Multiple sclerosis (MS) is a chronic condition affecting the central nervous system, often causing fatigue, postural in… | Scientific reports 2026-08-08 00:55:57 | Source |
| Drug-induced dysphagia: Analysis of age and time of onset profiles us… paroxetine · PMID 42544525 | Migraine · Sclérose en plaques · Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source To investigate differences in drug-induced dysphagia profiles among causative drugs, with a focus on reporting risk, pa… | International journal of clinical pharmacology and the… 2026-08-08 00:55:56 | Source |
| Effects of antidepressant administration on physical performance and… paroxetine · PMID 42560424 | Migraine · Sclérose en plaques · Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source Antidepressants are commonly prescribed in athletes with depressive disorders, yet their potential effects on physical… | International journal of clinical pharmacy 2026-08-08 00:55:56 | Source |
| Can Omegaven Avoid the Destructive Effect of Procarbazine Over Ovaria… blood sample to analyse AMH level on the serum · PMID 42440830 | Sclérose en plaques | Immunomodulation | Publication | PubMed | Voir la publication source Procarbazine, an alkylating agent, depletes ovarian reserve. Omegaven exhibits anti-apoptotic, anti-inflammatory, and a… | Reproductive medicine and biology 2026-08-08 00:55:55 | Source |
| GPR17 - orphan G protein-coupled receptor with therapeutic potential. PTD802 · PMID 40544085 | Sclérose en plaques | Remyélinisation | Publication | PubMed | Voir la publication source The orphan G protein-coupled receptor (GPCR) GPR17, whose physiological agonist remains unknown, has emerged as a promi… | Trends in pharmacological sciences 2026-08-08 00:55:55 | Source |
| Serum anti-Müllerian hormone response to pyrroloquinoline quinone sup… blood sample to analyse AMH level on the serum · PMID 42500134 | Sclérose en plaques | Remyélinisation indirecte / réparation · Neuroprotection | Publication | PubMed | Voir la publication source Oocyte maturation requires substantial ATP, and the resulting oxidative stress may impair follicular development. Pyrro… | Frontiers in endocrinology 2026-08-08 00:55:55 | Source |
| Experience of using anti-CD 20 therapies in multiple sclerosis patien… Ocrelizumab 600 mg · PMID 41669530 | Sclérose en plaques | Traitement symptomatique | Publication | PubMed | Voir la publication source The objective of the study was to evaluate the safety and efficacy of ocrelizumab (OCR) and rituximab (RTX) in multiple… | Frontiers in neurology 2026-08-08 00:55:53 | Source |
| Differential safety profiles of disease-modifying therapies in MS: Ag… Ocrelizumab 300 mg · PMID 42107470 | Sclérose en plaques | Ralentissement de la progression | Publication | PubMed | Voir la publication source Age and sex may modulate adverse events (AE) under disease-modifying therapies (DMTs) in Multiple Sclerosis (MS), yet c… | Multiple sclerosis and related disorders 2026-08-08 00:55:52 | Source |
| Reinitiating ocrelizumab with a full 600 mg dose after extended treat… Ocrelizumab 300 mg · PMID 42153199 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source Infusion-related reactions (IRRs) are a common side-effect of ocrelizumab (OCR), with the highest risk occurring during… | Multiple sclerosis journal - experimental, translation… 2026-08-08 00:55:52 | Source |
| 6-Mercaptopurine metabolic profiles and clinical outcomes in TPMT and… Intervention group IM-IM · PMID 42249522 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source This study aimed to investigate the real-world profiles of 6-mercaptopurine (6-MP) treatment in various TPMT/NUDT15 phe… | British journal of clinical pharmacology 2026-08-08 00:55:51 | Source |
| Diagnostic value of combined flow cytometry-based detection of periph… Intervention group IM-IM · PMID 42403386 | Sclérose en plaques | Immunomodulation | Publication | PubMed | Voir la publication source Pediatric infectious mononucleosis (IM) caused by Epstein-Barr virus (EBV) poses diagnostic challenges due to overlappi… | Frontiers in pediatrics 2026-08-08 00:55:51 | Source |
| Can a virtual reality tool detect minor executive functions impairmen… Comparison of Two Different Virtual Reality Methods in Patients With Multiple Sclerosis · PMID… | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source Traditional neuropsychological tests do not always identify executive disorders in patients with multiple sclerosis (MS… | Revue neurologique 2026-08-08 00:55:50 | Source |
| Evidence of attentional impairments using virtual driving simulation… Comparison of Two Different Virtual Reality Methods in Patients With Multiple Sclerosis · PMID… | Sclérose en plaques | Ralentissement de la progression | Publication | PubMed | Voir la publication source Detection of attentional disorders in complex situation related to daily life activities in multiple sclerosis patients… | Multiple sclerosis and related disorders 2026-08-08 00:55:50 | Source |
| Salvage treatment of forearm arteriovenous fistula with small caliber… Venous PTA · PMID 38087648 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source Dysfunctional distal arteriovenous fistulas (AVFs) with small caliber distal inflow arteries theoretically require perc… | The journal of vascular access 2026-08-08 00:55:48 | Source |
| Surgical management of post-thrombotic syndrome in chronic venous tho… Venous PTA · PMID 33429091 | Sclérose en plaques | Ralentissement de la progression · Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Venous thoracic outlet syndrome (VTOS) is considered chronic when symptoms and venous stenosis or occlusion are present… | Journal of vascular surgery. Venous and lymphatic diso… 2026-08-08 00:55:48 | Source |
| Adaptive, Stepped-Care for Cancer-Related PTSD Symptoms in HCT Surviv… Escalation Therapies Group · PMID 42565481 | Cancer | Traitement symptomatique | Publication | PubMed | Voir la publication source Cancer-related posttraumatic stress disorder (PTSD) is prevalent among hematopoietic cell transplantation (HCT) survivo… | Psycho-oncology 2026-08-08 00:55:47 | Source |
| Improved Outcomes with Early Aggressive Therapy in Pediatric Pulmonar… Escalation Therapies Group · PMID 42562588 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Pediatric pulmonary arterial hypertension (PAH) carries high mortality with 81% 5-year transplant-free survival. The gl… | The European respiratory journal 2026-08-08 00:55:47 | Source |
| Piloting a Digital App Based on the Friendship Bench for Depression a… Early Highly Effective Therapies Group · PMID 42555954 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source The burden of mental disorders is high in conflict-affected populations. In Palestine, we piloted Inuka Coaching, a dig… | JMIR mental health 2026-08-08 00:55:47 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||