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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Long-term neuropsychiatric outcomes after neuromodulation in epilepsy… ANT recording and stimulation · PMID 42530840 | Épilepsie | Traitement symptomatique | Publication | PubMed | Voir la publication source Neuromodulation therapies, including vagus nerve stimulation (VNS), anterior nucleus of the thalamus deep brain stimula… | Acta neurologica Belgica 2026-08-08 00:58:21 | Source |
| Abdominal Wall Erythema as a Suspected Extracardiac Manifestation of… Intravenous immunoglobulin · PMID 42564926 | Épilepsie | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source In a heart transplant recipient, a new cutaneous finding can be difficult to attribute to a single cause, and the clini… | Cureus 2026-08-08 00:58:20 | Source |
| Safety and tolerability of a new intravenous immunoglobulin 10% in pa… Intravenous immunoglobulin · PMID 42565276 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Kedrion IVIg 10% (KIg10; QIVIGY) is a new, ready-to-use, 10% liquid IVIg (100 mg/mL) approved for adults with primary i… | Immunotherapy 2026-08-08 00:58:20 | Source |
| Intracellular neuronal recordings across DNA tiles. Standard electrodes · PMID 42225982 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Transmembrane ionic flow through artificial ion channels is integral to the development of biohybrid electronics, such… | Nature nanotechnology 2026-08-08 00:58:19 | Source |
| Physio-fUS: a tissue-motion based method for heart and breathing rate… Standard electrodes · PMID 39889372 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Recent studies have shown growing evidence that brain function is closely synchronised with global physiological parame… | EBioMedicine 2026-08-08 00:58:19 | Source |
| Sex-related molecular phenotypes in anxiety-depressive disorders: a m… retrospective analysis of a panel result · PMID 42564216 | Épilepsie | Traitement symptomatique | Publication | PubMed | Voir la publication source Anxiety disorders and depressive disorders are the most prevalent mental disorders worldwide. Their diagnosis has long… | Frontiers in psychiatry 2026-08-08 00:58:18 | Source |
| Validation of SeptiCyte RAPID to Discriminate Sepsis From Noninfectio… retrospective analysis of a panel result · PMID 42565662 | Épilepsie | Immunomodulation | Publication | PubMed | Voir la publication source Biomarkers with adequate precision to rule-in/rule-out sepsis in children represent an unmet need. SeptiCyte RAPID is a… | Pediatric critical care medicine : a journal of the So… 2026-08-08 00:58:18 | Source |
| Lacosamide Use After Traumatic Brain Injury: A Scoping Review. Lacosamide · PMID 42558887 | Épilepsie | Neuroprotection · Immunomodulation | Publication | PubMed | Voir la publication source Lacosamide (LCM) is a newer antiepileptic drug that enhances slow inactivation of voltage-gated sodium channels and mod… | Cureus 2026-08-08 00:58:14 | Source |
| Retrospective, Multicenter Study of Lacosamide to Treat Neonatal Seiz… Lacosamide · PMID 42563900 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Most antiseizure medications (ASMs) are prescribed off label for neonates. Lacosamide's efficacy in infants and availab… | Annals of the Child Neurology Society 2026-08-08 00:58:14 | Source |
| Combined Functional Electrical and Transcranial Direct Current Stimul… Transcranial Direct Current Stimulation (TDCS) · PMID 42564268 | Accident vasculaire cérébral | Ralentissement de la progression | Publication | PubMed | Voir la publication source Stroke is a leading cause of severe long-term disability, and foot drop is a common post-stroke gait impairment that ma… | Journal of medical cases 2026-08-08 00:58:13 | Source |
| Electrophysiological biomarkers for foundational signal markers in ch… ECG Vector Determination · PMID 42558996 | Épilepsie | Traitement symptomatique | Publication | PubMed | Voir la publication source Most patients with chronic pancreatitis (CP) experience abdominal pain, but the pathophysiology differs. We aimed to in… | Frontiers in pain research (Lausanne, Switzerland) 2026-08-08 00:58:08 | Source |
| WAVE: Wall-Aligned Vector Embedding for Self-Supervised Learning of E… ECG Vector Determination · PMID 42510400 | Épilepsie | Thérapie génique | Publication | PubMed | Voir la publication source Deep learning has achieved remarkable progress in electrocardiogram (ECG) analysis, but its heavy dependence on labeled… | Bioengineering (Basel, Switzerland) 2026-08-08 00:58:08 | Source |
| SIRT1 in brain aging: molecular mechanisms and therapeutic potential… Metformin · PMID 42566092 | Cancer · Épilepsie · Hypertension artérielle · Myopathies · Maladie d… | Neuroprotection · Ralentissement de la progression · Immunomodulation | Publication | PubMed | Voir la publication source Aging is a multifactorial process affects different tissues and organs and is modulated by genetic and environmental fa… | Biogerontology 2026-08-08 00:58:07 | Source |
| Time to Insulin Initiation Among Patients With Type 2 Diabetes Treate… Metformin · PMID 42563367 | Cancer · Épilepsie · Hypertension artérielle · Myopathies · Maladie d… | À vérifier | Publication | PubMed | Voir la publication source To examine the effect of second-line treatments (insulin secretagogues, thiazolidinediones, glucagon-like peptide-1 (GL… | Diabetes, obesity & metabolism 2026-08-08 00:58:07 | Source |
| A Case of Lamotrigine-Induced Drug Reaction With Eosinophilia and Sys… Levetiracetam &/or sodium valproate · PMID 42559111 | Épilepsie | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source We report a case of severe drug reaction with eosinophilia and systemic symptoms (DRESS) associated with early coagulat… | Acute medicine & surgery 2026-08-08 00:58:06 | Source |
| Harnessing Repurposed Drugs to Enhance Temozolomide Efficacy in Gliob… Levetiracetam &/or sodium valproate · PMID 42557676 | Cancer | Neuroprotection · Thérapie cellulaire | Publication | PubMed | Voir la publication source Glioblastoma (GB) is the most aggressive primary malignant brain tumor in adults and remains associated with poor survi… | Cancer reports (Hoboken, N.J.) 2026-08-08 00:58:06 | Source |
| Age-related trajectories in epileptogenesis and neurological function… Cortical Excitability in Post-traumatic Epilepsy · PMID 42492829 | Épilepsie | Immunomodulation | Publication | PubMed | Voir la publication source Post-traumatic epilepsy (PTE) is a debilitating long-term consequence of traumatic brain injury (TBI), yet the influenc… | Experimental neurology 2026-08-08 00:58:05 | Source |
| A systematic review and meta-analysis of acupuncture for intestinal p… Acupuncture intervention · PMID 42536534 | Épilepsie | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Although acupuncture has exhibited potential in the therapy of ulcerative colitis (UC), its particular protective mecha… | Medicine 2026-08-08 00:58:05 | Source |
| Right amygdala ablation reduces maladaptive negative interpretation b… Cortical Excitability in Post-traumatic Epilepsy · PMID 42331801 | Épilepsie | Traitement symptomatique | Publication | PubMed | Voir la publication source Negative interpretation bias - the tendency to perceive ambiguous stimuli as threatening - is a core cognitive distorti… | Nature communications 2026-08-08 00:58:05 | Source |
| Screw-Thread Needle Mediated In Situ Delivery of Tangeretin@β-Cyclode… Acupuncture intervention · PMID 42555530 | Épilepsie | Immunomodulation | Publication | PubMed | Voir la publication source Achilles tendinitis (AT) has posed as an intractable clinical problem, for which there is currently a lack of satisfact… | ACS applied bio materials 2026-08-08 00:58:05 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||