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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| The role of prodromal symptoms in predicting headache onset: A longit… PREDI-CRISIS — Migraine Attack Pain Phase Prediction Study · PMID 42260720 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source This longitudinal observational study investigated the role of prodromal symptoms in predicting headache onset, using e… | Headache 2026-08-08 00:59:06 | Source |
| Assessing the effectiveness of greater occipital nerve block in chron… Greater Occipital Nerve Block (GONB) · PMID 39244547 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Chronic migraine poses a global health burden, particularly affecting young women, and has substantial societal implica… | BMC neurology 2026-08-08 00:59:05 | Source |
| Comparison of the Effectiveness of Greater Occipital Nerve Block and… Greater Occipital Nerve Block (GONB) · PMID 42005143 | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Background Chronic migraine, defined as ≥15 headache days/month with ≥8 migraine days, is a disabling condition with li… | Cureus 2026-08-08 00:59:05 | Source |
| Metoclopramide-Induced Hyperprolactinemia Mimicking Prolactinoma in a… OnabotulinumtoxinA · PMID 42549416 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Hyperprolactinemia accompanied by headache and visual symptoms commonly prompts pituitary imaging to rule out prolactin… | Cureus 2026-08-08 00:59:04 | Source |
| Feasibility and effect of mindfulness approach by web for chronic mig… MINDKIDS — Mindfulness for Adolescents for CM and HFEM · PMID 35788839 | Migraine | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Migraine disorders are common among adolescents: however, the efficacy of medical prophylaxis is limited in this popula… | Neurological sciences : official journal of the Italia… 2026-08-08 00:59:03 | Source |
| A multi-centre, tolerability study of a cannabidiol-enriched Cannabis… MPL-001 · PMID 39302982 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Cannabis products have been used in the management of headaches in adults and may play a role in pediatric chronic pain… | PloS one 2026-08-08 00:59:02 | Source |
| Cannabidiol to reduce persistent post-surgical pain following total k… MPL-001 · PMID 42032682 | Migraine | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Total knee arthroplasty (TKA) is commonly performed to reduce pain and improve functional limitations associated with l… | Pilot and feasibility studies 2026-08-08 00:59:02 | Source |
| Aspirin for Venous Thromboembolism Prevention in Orthopaedic Surgery… Aspirin (acetylsalicylic acid) · PMID 42355718 | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Venous thromboembolism (VTE) remains a clinically relevant complication following major orthopaedic procedures, particu… | Journal of clinical medicine 2026-08-08 00:59:01 | Source |
| Association Between Low-Dose Aspirin Use and Early Renal Injury Bioma… Aspirin (acetylsalicylic acid) · PMID 42436762 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Microalbuminuria and urine albumin-to-creatinine ratio (UACR) are important markers for early diabetic kidney disease (… | Diabetes, metabolic syndrome and obesity : targets and… 2026-08-08 00:59:01 | Source |
| Auditory neuromodulation-based prescription digital therapeutic for i… sham device · PMID 42426835 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Insomnia affects 10-15% of adults worldwide, significantly impairing quality of life, cognitive function, and work prod… | Trials 2026-08-08 00:59:00 | Source |
| Normative Data for a Multi-Domain Concussion Assessment in the Female… The Role Of Vestibular Rehabilitation Therapy In Management Of Vestibular Migraine Patients ·… | Migraine | Ralentissement de la progression | Publication | PubMed | Voir la publication source Due to the highly individualised presentation of sport-related concussion (SRC), multi-domain assessments examining cog… | Sports (Basel, Switzerland) 2026-08-08 00:59:00 | Source |
| Self-powered electronics-free Wearable Disposable Electrotherapy (WDE… sham device · PMID 42539150 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Electrical stimulation accelerates wound repair by modulating endogenous bioelectric signals that regulate inflammation… | bioRxiv : the preprint server for biology 2026-08-08 00:59:00 | Source |
| The effect of vestibular rehabilitation in the management of vestibul… The Role Of Vestibular Rehabilitation Therapy In Management Of Vestibular Migraine Patients ·… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Vestibular migraine (VM) is a common migraine subtype characterized by recurrent vestibular symptoms. Despite its preva… | Headache 2026-08-08 00:59:00 | Source |
| Post-Craniotomy Headache: Current Concepts and Emerging Procedural Th… Calcitonin Gene-Related Peptide · PMID 42554893 | Migraine | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Post-craniotomy headache (PCH) is a common complication following neurosurgery, yet there remains limited consensus reg… | Current pain and headache reports 2026-08-08 00:58:59 | Source |
| Interventional Diagnostic Procedure: a Practical Guide for the Assess… MR-angiography, GTN · PMID 35377363 | Maladie coronarienne | Traitement symptomatique | Publication | PubMed | Voir la publication source Approximately 40% of patients undergoing invasive coronary angiography for investigation of angina are found to have no… | Journal of visualized experiments : JoVE 2026-08-08 00:58:57 | Source |
| Intracerebral hemorrhage as initial presentation of metastatic chorio… MR-angiography, GTN · PMID 32994836 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Metastatic brain tumors are the rare cause of intracerebral hemorrhage in the young. In this study, we present a case o… | Radiology case reports 2026-08-08 00:58:57 | Source |
| Clinical Investigation of the Safety and Effectiveness of the Occlute… PFO occlusion · PMID 41919017 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source The Prospective Randomized Multi-center Controlled Clinical Investigation Comparing Patent Foramen Ovale (PFO) Outcomes… | Journal of the Society for Cardiovascular Angiography… 2026-08-08 00:58:56 | Source |
| Right-dominant arrhythmogenic cardiomyopathy complicated by platypnea… PFO occlusion · PMID 41847562 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Platypnea-orthodeoxia syndrome (POS) is a rare but treatable cause of positional hypoxaemia, typically associated with… | European heart journal. Case reports 2026-08-08 00:58:56 | Source |
| A scoping review for published guidelines for use of ketamine in chro… ketamine infusion · PMID 42533509 | Cancer | Traitement symptomatique | Publication | PubMed | Voir la publication source Off-label ketamine infusions are often used to manage chronic non-cancer pain (CNCP), including neuropathic pain, centr… | Anaesthesia and intensive care 2026-08-08 00:58:55 | Source |
| Long-Term Effectiveness of Repeated, Single-Day Intravenous Ketamine… ketamine infusion · PMID 42550528 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Ketamine, either adminstered as an infusion or orally as an analgesic, was considered only to be a drug for neuropathic… | Pain physician 2026-08-08 00:58:55 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||