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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Comparing synthetic and biological therapy for the treatment of clust… Galcanezumab · PMID 42493477 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Cluster headache is an extremely painful and severely disabling primary headache disorder that, despite its profound im… | Expert review of neurotherapeutics 2026-08-08 00:59:58 | Source |
| Compound Chamomile and Lidocaine Hydrochloride Gel in Oral Diseases:… Lidocaine Hydrochloride · PMID 42558651 | Migraine · Myopathies · Migraine | Immunomodulation · Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Oral diseases frequently entail microbial infections or mucosal damage, typically accompanied by pain and discomfort. P… | Drug design, development and therapy 2026-08-08 00:59:57 | Source |
| Impact of Menthol Concentration on Ketoprofen Permeation and Photosta… Lidocaine Hydrochloride · PMID 42518428 | Migraine · Myopathies · Migraine | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Topical nonsteroidal anti-inflammatory drugs provide localized pain relief while reducing the risk of systemic adverse… | ACS omega 2026-08-08 00:59:57 | Source |
| Active machine learning model for the dynamic simulation and growth m… TI-001 · PMID 38184678 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Substrate-catalyzed growth offers a highly promising approach for the controlled synthesis of carbon nanostructures. Ho… | Nature communications 2026-08-08 00:59:56 | Source |
| Combined Occipital Nerve and Sphenopalatine Ganglion Neuromodulation… Occipital Nerve Stimulation · PMID 42100751 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Craniofacial complex regional pain syndrome (CRPS) is a rare, diagnostically challenging condition characterized by sym… | Local and regional anesthesia 2026-08-08 00:59:56 | Source |
| Comparative Efficacy and Acceptability of Noninvasive Brain Stimulati… Occipital Nerve Stimulation · PMID 42473074 | Migraine | À vérifier | Publication | PubMed | Voir la publication source This network meta-analysis (NMA) aimed to compare and rank the efficacy and acceptability of different noninvasive brai… | Brain and behavior 2026-08-08 00:59:56 | Source |
| TiO2 nanotubes: interdependence of substrate grain orientation and gr… TI-001 · PMID 25545715 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Highly ordered arrays of TiO2 nanotubes can be produced by self-organized anodic growth. It is desirable to identify ke… | ACS applied materials & interfaces 2026-08-08 00:59:56 | Source |
| International Headache society evidence-based guidelines on the use o… Nerivio Migra-1 Sham device · PMID 41117312 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source ObjectiveTo develop evidence-based clinical practice guidelines for non-invasive neuromodulation devices in acute and p… | Cephalalgia : an international journal of headache 2026-08-08 00:59:54 | Source |
| Plasma Phosphorylated Tau 217 in Participants at Risk for Chronic Tra… BE WELL With Migraine: Brain Education and WELLness With Migraine · PMID 42440317 | Maladie d’Alzheimer | Traitement symptomatique | Publication | PubMed | Voir la publication source In vivo biomarkers for detecting neuropathologies from repetitive head impacts (RHI), including chronic traumatic encep… | JAMA network open 2026-08-08 00:59:53 | Source |
| Weight loss with atogepant in the long-term treatment of migraine: An… BE WELL With Migraine: Brain Education and WELLness With Migraine · PMID 42396885 | Migraine | À vérifier | Publication | PubMed | Voir la publication source To assess weight loss with atogepant 60 mg once daily during long-term treatment of chronic migraine (CM) and episodic… | Headache 2026-08-08 00:59:53 | Source |
| Cellulose and Its Derivatives in Drug Delivery: Recent Advances and A… sumatriptan succinate · PMID 42198288 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Drug delivery systems have long faced a fundamental challenge: achieving high drug-loading efficiency, precise control… | Pharmaceutics 2026-08-08 00:59:51 | Source |
| Spatial metabolomics combined with MALDI-MSI unveils gut-brain axis m… sumatriptan succinate · PMID 41619552 | Migraine | Immunomodulation · Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Migraine is a highly disabling neurological disorder characterized by recurrent headaches and complex metabolic disturb… | Phytomedicine : international journal of phytotherapy… 2026-08-08 00:59:51 | Source |
| Drugs targeting nitric oxide synthase for migraine treatment. NXN-188 · PMID 24818644 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Ample evidence that nitric oxide (NO) is a causative molecule in migraine has encouraged research to develop drugs that… | Expert opinion on investigational drugs 2026-08-08 00:59:50 | Source |
| The nitric oxide synthase inhibitor and serotonin-receptor agonist NX… NXN-188 · PMID 29913885 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Background and aims NXN-188 is a combined neuronal nitric oxide synthase (nNOS) inhibitor and 5HT-1B/1D receptor agonis… | Scandinavian journal of pain 2026-08-08 00:59:50 | Source |
| Identifying central positional vertigo to prevent diagnostic pitfalls… Vestibular System in Migrainous Vertigo Patients · PMID 42564662 | Accident vasculaire cérébral · Migraine | À vérifier | Publication | PubMed | Voir la publication source This case series highlights the critical role of radiological imaging in patients presenting with positional vertigo in… | Radiology case reports 2026-08-08 00:59:48 | Source |
| Quantitative pupillometry as a marker of autonomic dysregulation in v… Vestibular System in Migrainous Vertigo Patients · PMID 42548108 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Vestibular migraine (VM) has been associated with altered central sensory processing; however, objective measures of au… | Journal of oral & facial pain and headache 2026-08-08 00:59:48 | Source |
| Arterial hepatic perfusion is preserved during early resuscitation af… blood withdrawal · PMID 42431156 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Hemorrhagic shock is a major contributor to morbidity and mortality after polytrauma and plays a central role in the de… | Injury 2026-08-08 00:59:47 | Source |
| Long peripheral catheters for short-term vascular access: A 7-day obs… blood withdrawal · PMID 42438309 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Long peripheral catheters are increasingly used as an alternative to short peripheral catheters for short-term intraven… | The journal of vascular access 2026-08-08 00:59:47 | Source |
| A Real-World Evidence Study on US Patients Demonstrating Safety of Hi… Nerivio ® · PMID 41886224 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Remote electrical neuromodulation (REN) is an FDA-cleared, nonsignificant-risk, drug-free, prescribed wearable device (… | Pain and therapy 2026-08-08 00:59:45 | Source |
| Association of adverse childhood experiences with physical illness an… Brief Interventions in Chronic Migraine · PMID 40194777 | Hypertension artérielle · Insuffisance cardiaque · Maladie coronarien… | Traitement symptomatique | Publication | PubMed | Voir la publication source Adverse childhood experiences (ACEs) are highly prevalent and associated with life-long health consequences. Here, we i… | European journal of public health 2026-08-08 00:59:45 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||