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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Hypertension and myocardial fibrosis: A systematic review and meta-an… Perindopril (T1) · PMID 42296937 | Hypertension artérielle · Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Hypertension (HTN) is a major risk factor for myocardial fibrosis (MF), a key contributor to cardiac dysfunction. This… | Clinical radiology 2026-08-08 01:00:45 | Source |
| Takotsubo syndrome in a cancer patient treated with a combination of… Perindopril (T1) · PMID 39104513 | Cancer | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Takotsubo syndrome (TTS) is characterized by transient regional left ventricular (LV) dysfunction occurring in individu… | European heart journal. Case reports 2026-08-08 01:00:45 | Source |
| Selection and potential of cholesterol-lowering indigenous probiotic:… Effects of Xoçai Antioxidant Supplements on Atherosclerosis Risk Factors · PMID 41168307 | Hypertension artérielle | Neuroprotection | Publication | PubMed | Voir la publication source Atherosclerosis, a prevalent cardiovascular disorder, is ineffectively managed by statins, highlighting the need for na… | Scientific reports 2026-08-08 01:00:40 | Source |
| Watermelon Nutritional Composition with a Focus on L-Citrulline and I… Effects of Xoçai Antioxidant Supplements on Atherosclerosis Risk Factors · PMID 41156475 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Nitric oxide is a gaseous molecule endogenously produced by endothelial cells, which stands out for its vascular tone r… | Nutrients 2026-08-08 01:00:40 | Source |
| Prevalence and prognostic significance of untreated, uncontrolled and… doublepres — The Diagnosis and Treatment of Resistant Hypertension, the Prevalence and the Pro… | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source The prevalence of untreated, uncontrolled and resistant hypertension and their specific prognosis among American adults… | Blood pressure 2026-08-08 01:00:38 | Source |
| Scleroderma Renal Crisis and Posterior Reversible Encephalopathy Synd… enalapril · PMID 42543578 | Hypertension artérielle · Maladie rénale chronique | Immunomodulation | Publication | PubMed | Voir la publication source Scleroderma renal crisis (SRC) and posterior reversible encephalopathy syndrome (PRES) are rare but severe complication… | Internal medicine (Tokyo, Japan) 2026-08-08 01:00:38 | Source |
| Spironolactone therapy in resistant hypertension comorbid with mild o… doublepres — The Diagnosis and Treatment of Resistant Hypertension, the Prevalence and the Pro… | Hypertension artérielle | Traitement symptomatique | Publication | PubMed | Voir la publication source Mild obstructive sleep apnea (OSA) is often underdiagnosed but contributes to treatment-resistant hypertension through… | Medicine 2026-08-08 01:00:38 | Source |
| Blood pressure knowledge in hypertensive hemodialysis patients. Improving Blood Pressure Control in End-Stage Renal Disease Through a Supportive-Educative Nur… | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source The major purpose of this quantitative study was to determine if a supportive educative nursing intervention incorporat… | CANNT journal = Journal ACITN 2026-08-08 01:00:36 | Source |
| Improving blood pressure control in end stage renal disease through a… Improving Blood Pressure Control in End-Stage Renal Disease Through a Supportive-Educative Nur… | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Hypertension in patients on hemodialysis (HD) contributes significantly to their morbidity and mortality. This study ex… | Nephrology nursing journal : journal of the American N… 2026-08-08 01:00:36 | Source |
| Late-Onset Infectious Keratitis over 10 Years after Intracorneal Ring… Telemedicine · PMID 42564943 | Hypertension artérielle | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Intracorneal ring segments (ICRS) are employed to manage keratoconus but carry the risk of late-onset complications suc… | Case reports in ophthalmology 2026-08-08 01:00:35 | Source |
| Telemedicine Critical Care Billing For Hospitalized Medicare Fee-For-… Telemedicine · PMID 42565664 | Hypertension artérielle | Thérapie génique | Publication | PubMed | Voir la publication source Expanded coverage for telehealth during the COVID-19 pandemic allowed providers to bill for telemedicine services that… | Critical care medicine 2026-08-08 01:00:35 | Source |
| Implementing virtual diabetes self-management education in two health… VIDA — Virtual Diabetes Group Visits Across Health Systems · PMID 42433307 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Group-based diabetes self-management education (DSME) has long been shown to improve health outcomes, but how to effect… | Frontiers in clinical diabetes and healthcare 2026-08-08 01:00:34 | Source |
| A Custom-Built Intravoxel Incoherent Motion Diffusion Magnetic Resona… Magnetic Resonance Imaging for Evaluating Kidney Function · PMID 42538664 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source In this study, we present a custom -developed, Python -based graphical user interface designed to address the limitatio… | Experimental and clinical transplantation : official j… 2026-08-08 01:00:33 | Source |
| Multiparametric MR Imaging for Detecting Early Chronic Kidney Disease… Magnetic Resonance Imaging for Evaluating Kidney Function · PMID 42560709 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source Conventional renal function markers, such as estimated glomerular filtration rate (eGFR), often fail to reflect occult… | Journal of magnetic resonance imaging : JMRI 2026-08-08 01:00:33 | Source |
| A Proposed Model of a Pragmatic Surgical Approach in Women Affected b… myoma removal · PMID 41517627 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source : Uterine fibroids are the most common benign neoplasms of the female genital tract, with a prevalence of 20% to 40% am… | Journal of clinical medicine 2026-08-08 01:00:32 | Source |
| Feasibility and effectiveness of hysteroscopic myomectomy for type 3… myoma removal · PMID 41560938 | Hypertension artérielle | Thérapie génique | Publication | PubMed | Voir la publication source This study aimed to evaluate the feasibility and effectiveness of hysteroscopic myomectomy for treating International F… | Frontiers in surgery 2026-08-08 01:00:32 | Source |
| Renal Denervation to Treat Hypertension: A Clinical State-of-the-Art… Paradise Ultrasound Renal Denervation Treatment · PMID 40702973 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Hypertension represents the leading risk factor for death globally, affecting one in two adults. Despite dozens of inex… | American journal of hypertension 2026-08-08 01:00:31 | Source |
| Dose optimization of sacubitril/valsartan in Chinese chronic heart fa… Sacubitril/valsartan · PMID 42558440 | Hypertension artérielle · Insuffisance cardiaque | Thérapie génique | Publication | PubMed | Voir la publication source In routine clinical practice, many patients with chronic heart failure (CHF) treated with sacubitril/valsartan do not a… | Frontiers in pharmacology 2026-08-08 01:00:29 | Source |
| In symptomatic HF, sacubitril-valsartan vs. dapagliflozin and torsemi… Sacubitril/valsartan · PMID 42546309 | Hypertension artérielle | Traitement symptomatique | Publication | PubMed | Voir la publication source GIM/FP/GP: [Formula: see text] Cardiology: [Formula: see text]. | Annals of internal medicine 2026-08-08 01:00:29 | Source |
| Additive beneficial effects of valsartan combined with rosuvastatin i… Valsartan 160 mg + Rosuvastatin 20 mg · PMID 26023311 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source We compared the efficacy and safety of valsartan and rosuvastatin combination therapy with each treatment alone in hype… | Korean circulation journal 2026-08-08 01:00:28 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||