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Périmètre
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Chaque choix s’applique immédiatement aux quatre sections. Le filtre « type de SEP » n’apparaît que lorsque la sclérose en plaques est sélectionnée.
10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Comparative Effectiveness of Diroximel Fumarate vs. Dimethyl Fumarate… Vumerity · PMID 42060157 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source Diroximel fumarate (DRF) and dimethyl fumarate (DMF) are established disease-modifying therapies for relapsing multiple… | Advances in therapy 2026-08-13 14:19:52 | Source |
| Comparative Efficacy and Safety of Ebastine 20 mg, Ebastine 10 mg and… Desloratadine given orally · PMID 28511488 | Sclérose en plaques | Traitement symptomatique | Publication | PubMed | Voir la publication source Acute and chronic urticaria can result in severely impaired quality of life from pruritus and associated sleep lessness… | Journal of clinical and diagnostic research : JCDR 2026-08-13 14:19:51 | Source |
| The effect of desloratadine on ischemia reperfusion induced oxidative… Desloratadine given orally · PMID 32524906 | Sclérose en plaques | Immunomodulation | Publication | PubMed | Voir la publication source To examine the effect of desloratadine on kidney ischemia-reperfusion (I/R) injury in albino Wistar male rats using bio… | Renal failure 2026-08-13 14:19:51 | Source |
| Evaluation of the effects of A-PRF and oral dexamethasone use on post… Dexamethasone given orally · PMID 42421033 | Sclérose en plaques | Traitement symptomatique | Publication | PubMed | Voir la publication source The aim of this study was to compare the effects of advanced platelet-rich-fibrin (A-PRF) and oral dexamethasone on pos… | BMC oral health 2026-08-13 14:19:50 | Source |
| Safety analyses of the INAVO120 randomised phase III trial of inavoli… Dexamethasone given orally · PMID 42202490 | Cancer | Ralentissement de la progression · Immunomodulation | Publication | PubMed | Voir la publication source INAVO120 (NCT04191499) demonstrated significantly improved progression-free/overall survival with inavolisib plus palbo… | ESMO open 2026-08-13 14:19:50 | Source |
| A Case Report of Venezuelan Suntiger Tarantula (Psalmopoeus Irminia)… Diphenhydramine IV · PMID 37635034 | Sclérose en plaques | Traitement symptomatique | Publication | PubMed | Voir la publication source Tarantula envenomations are encountered infrequently but may increase with increased exotic animal ownership. This case… | The Journal of emergency medicine 2026-08-13 14:19:49 | Source |
| The Role of Cetirizine in the Changing Landscape of IV Antihistamines… Diphenhydramine IV · PMID 34862952 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source Since 1955, the only available H antihistamines for intravenous administration have been first-generation formulations… | Advances in therapy 2026-08-13 14:19:49 | Source |
| Immune Checkpoint Inhibitor Therapy Induced Hypophysitis; A Tertiary… Methylprednisolone IV · PMID 41879139 | Cancer | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source The number of patients receiving immune checkpoint inhibitor (ICI) therapy for cancer is expected to increase further;… | Clinical endocrinology 2026-08-13 14:19:48 | Source |
| Probable Autoimmune Encephalitis Presenting With Catatonia in a Young… Methylprednisolone IV · PMID 40952037 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source ObjectiveTo describe a case of probable autoimmune encephalitis initially misdiagnosed as a primary psychiatric disorde… | International journal of psychiatry in medicine 2026-08-13 14:19:48 | Source |
| Relative increase of memory B-cell subsets under s.c. B-cell-depletin… Ocrelizumab IV · PMID 42375380 | Sclérose en plaques | Immunomodulation | Publication | PubMed | Voir la publication source Monoclonal antibodies targeting CD20-expressing B cells constitute effective therapies for people with multiple scleros… | Frontiers in immunology 2026-08-13 14:19:46 | Source |
| Subcutaneous Ocrelizumab for the Treatment of Relapsing Forms of Mult… Ocrelizumab IV · PMID 42545439 | Sclérose en plaques | Ralentissement de la progression · Thérapie génique | Publication | PubMed | Voir la publication source The aim of this study was to evaluate the budget impact of introducing the subcutaneous (SC) form of ocrelizumab for pa… | PharmacoEconomics - open 2026-08-13 14:19:46 | Source |
| Enhancing everyday memory and participation in multiple sclerosis: A… Music-4-MS to Improve Cognition in People Living With Multiple Sclerosis: A Feasibility Study… | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source Cognitive dysfunction in individuals with multiple sclerosis (MS) is associated with limitations in daily activities an… | Multiple sclerosis journal - experimental, translation… 2026-08-13 14:19:44 | Source |
| Managing fatigue in Parkinson's disease: Preparing for a randomized c… Music-4-MS to Improve Cognition in People Living With Multiple Sclerosis: A Feasibility Study… | Maladie de Parkinson | Traitement symptomatique | Publication | PubMed | Voir la publication source BackgroundFatigue in Parkinson's disease (PD) is a common, debilitating symptom often overlooked in research and clinic… | Journal of Parkinson's disease 2026-08-13 14:19:44 | Source |
| Subcategorisation of Data for AI Models in Healthcare: A Case Study i… AI software · PMID 42587605 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source Accurate data subcategorising is vital for reliability and traceability in the training and validation of all artificia… | Diagnostics (Basel, Switzerland) 2026-08-13 14:19:43 | Source |
| Zero Risk Is Impossible: Confidentiality and Artificial Intelligence… AI software · PMID 42577012 | Sclérose en plaques | Thérapie génique | Publication | PubMed | Voir la publication source Most journals' and publishers' guidelines regarding the use of artificial intelligence (AI) in peer review contain a si… | JMA journal 2026-08-13 14:19:43 | Source |
| Comorbidities for Predicting Progression Independent of Relapse Activ… RRMS — Predictors of Progression Independent of Relapse Activity in Relapsing Remitting Multip… | Hypertension artérielle · Sclérose en plaques | Ralentissement de la progression | Publication | PubMed | Voir la publication source Progression independent of relapse activity (PIRA) has been shown to account for a majority of the disability accumulat… | European journal of neurology 2026-08-13 14:19:42 | Source |
| Longitudinal changes in serum protein levels are associated with disa… RRMS — Predictors of Progression Independent of Relapse Activity in Relapsing Remitting Multip… | Sclérose en plaques | Ralentissement de la progression | Publication | PubMed | Voir la publication source Early identification of patients with multiple sclerosis (MS) at risk of transitioning from relapsing-remitting multipl… | Multiple sclerosis and related disorders 2026-08-13 14:19:42 | Source |
| Effect of Telerehabilitation-Based Music Therapy and Motor Imagery on… Effect of Music Therapy on Pain in People With Multiple Sclerosis · PMID 41791797 | Sclérose en plaques | Traitement symptomatique | Publication | PubMed | Voir la publication source Chronic pain affects approximately 63% of people with multiple sclerosis (pwMS), contributing to fatigue, depression, a… | Physiotherapy research international : the journal for… 2026-08-13 14:19:41 | Source |
| Musical intervention to reduce stress during botulinum toxin injectio… Effect of Music Therapy on Pain in People With Multiple Sclerosis · PMID 41289288 | Accident vasculaire cérébral · Maladie d’Alzheimer · Sclérose en plaq… | Traitement symptomatique | Publication | PubMed | Voir la publication source Botulinum toxin injections are a common treatment for managing spasticity resulting from central nervous system damage,… | PloS one 2026-08-13 14:19:41 | Source |
| Comorbidities in multiple sclerosis: acquired hepatocerebral degenera… Magnetic Resonance Imaging (MRI) to Evaluate Activity of Multiple Sclerosis (MS) · PMID 425331… | Sclérose en plaques | Ralentissement de la progression · Thérapie génique | Publication | PubMed | Voir la publication source A 63-year-old patient with relapsing-remitting multiple sclerosis (MS) and comorbid liver cirrhosis presented with prog… | Neurological sciences : official journal of the Italia… 2026-08-13 14:19:39 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||