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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Auricular Ultrasonic Vagus Nerve Stimulation: Effectiveness of Blindi… Ultrasound Vagus Nerve Stimulation (U-VNS) · PMID 42352596 | Sclérose en plaques | Thérapie génique | Publication | PubMed | Voir la publication source : Vagus Nerve Stimulation (VNS) has been suggested as a treatment for tinnitus, but its effect on the condition remains… | Brain sciences 2026-08-13 14:20:41 | Source |
| Disruption of Plexin-A1 signaling by FTX-101: mode of action and effe… FTX-101 · PMID 40435840 | Sclérose en plaques | Remyélinisation | Publication | PubMed | Voir la publication source In the absence of effective remyelination therapies for neurodegenerative disorders, we have synthesized FTX-101, a the… | Biomedicine & pharmacotherapy = Biomedecine & pharmaco… 2026-08-13 14:20:40 | Source |
| Mechanistic Insights into the Aging and Regeneration of SBS-Modified… Saline · PMID 42590300 | Accident vasculaire cérébral · Maladie coronarienne · Migraine · Sclé… | Remyélinisation indirecte / réparation | Publication | PubMed | Voir la publication source The deterioration of SBS-modified asphalt under coupled temperature-ultraviolet (UV)-coastal humidity conditions is sig… | Materials (Basel, Switzerland) 2026-08-13 14:20:40 | Source |
| Neuropilins in Multiple Sclerosis: Dual Roles of NRP-1 in Neuroinflam… FTX-101 · PMID 42207333 | Sclérose en plaques | Remyélinisation · Neuroprotection · Ralentissement de la progression · Immunomo… | Publication | PubMed | Voir la publication source Neuropilins (NRPs), particularly NRP-1, are multifunctional co-receptors involved in neuroinflammatory and neuroprotect… | Neuromolecular medicine 2026-08-13 14:20:40 | Source |
| Nurses' and Families' Experiences of a Feasibility Trial Comparing Si… Saline · PMID 42591052 | Accident vasculaire cérébral · Maladie coronarienne · Migraine · Sclé… | À vérifier | Publication | PubMed | Voir la publication source In resource-limited Intensive Care Units (ICUs), reusing endotracheal suctioning catheters is often standard practice d… | Nursing in critical care 2026-08-13 14:20:40 | Source |
| Acthar Gel treatment in patients with rheumatoid arthritis, systemic… repository corticotropin injection · PMID 42347561 | Lupus | Traitement symptomatique | Publication | PubMed | Voir la publication source To examine the characteristics, treatment patterns, and physicians' assessments of outcomes for patients with rheumatoi… | Journal of comparative effectiveness research 2026-08-13 14:20:39 | Source |
| Adherence to Acthar Gel (RCI) and Outcomes in Patients with Membranou… repository corticotropin injection · PMID 41836914 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source To describe real-world patient characteristics and outcomes after initiation of Acthar Gel (repository corticotropin in… | ClinicoEconomics and outcomes research : CEOR 2026-08-13 14:20:39 | Source |
| Micro-Fragmented Adipose Tissue (MFAT) in Orthopedic Regenerative Med… Injection of autologous bone marrow derived mesenchymal stem cells · PMID 42511529 | Sclérose en plaques | Immunomodulation · Traitement symptomatique · Thérapie cellulaire | Publication | PubMed | Voir la publication source Micro-fragmented adipose tissue (mFAT) is a promising autologous biologic in regenerative medicine because it provides… | International journal of molecular sciences 2026-08-13 14:20:38 | Source |
| Responders vs. non-responders to mesenchymal stromal cells in knee os… Injection of autologous bone marrow derived mesenchymal stem cells · PMID 42561945 | Sclérose en plaques | Immunomodulation · Thérapie cellulaire · Thérapie génique | Publication | PubMed | Voir la publication source Mesenchymal stromal cell (MSC) injection has afforded heterogeneous outcomes in knee osteoarthritis (KOA). Herein, a fr… | Stem cell reports 2026-08-13 14:20:38 | Source |
| Allogeneic mesenchymal stromal cells ameliorate lupus nephritis by re… Allogeneic umbilical cord mesenchymal stem cells · PMID 42432741 | Lupus | Immunomodulation · Thérapie cellulaire | Publication | PubMed | Voir la publication source Systemic lupus erythematosus (SLE) is an autoimmune disease in which disruptions in lipid metabolism contribute to immu… | Stem cell research & therapy 2026-08-13 14:20:37 | Source |
| Mesenchymal stem cell therapy as adjunctive treatment in pediatric pa… Allogeneic umbilical cord mesenchymal stem cells · PMID 42523973 | Sclérose en plaques | Ralentissement de la progression · Immunomodulation · Thérapie cellulaire | Publication | PubMed | Voir la publication source Severe acquired brain injury in critically ill children-most commonly hypoxic-ischemic in origin-frequently results in… | Frontiers in pediatrics 2026-08-13 14:20:37 | Source |
| Association of Cerebrospinal Fluid-Restricted Oligoclonal Bands With… Evaluation of Relapse Presence in Multiple Sclerosis · PMID 42407394 | Sclérose en plaques | Remyélinisation · Thérapie génique | Publication | PubMed | Voir la publication source Cerebrospinal fluid (CSF)-restricted oligoclonal bands (OCBs) are observed in a minority of patients with pediatric mye… | Pediatric neurology 2026-08-13 14:20:36 | Source |
| Coordinated oxidative shift during relapse and recovery in multiple s… Evaluation of Relapse Presence in Multiple Sclerosis · PMID 42470870 | Sclérose en plaques | Neuroprotection · Ralentissement de la progression · Immunomodulation | Publication | PubMed | Voir la publication source Oxidative stress plays a central role in the pathogenesis of multiple sclerosis (MS), contributing to inflammation, dem… | Journal of neuroimmunology 2026-08-13 14:20:36 | Source |
| Exploring the Effects of Remotely Supervised Transcranial Direct Curr… Remotely Supervised Transcranial Direct Current Stimulation (RS - tDCS) · PMID 41960941 | Sclérose en plaques | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source BackgroundMultiple sclerosis (MS) is an autoimmune, inflammatory, progressive neurological disease. Individuals with MS… | NeuroRehabilitation 2026-08-13 14:20:34 | Source |
| Low intensity transcranial electric stimulation: Safety, ethical, leg… Remotely Supervised Transcranial Direct Current Stimulation (RS - tDCS) · PMID 41622107 | Sclérose en plaques | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source This guideline summarizes updated safety data (2017-2025) and provides expert recommendations on the use of low intensi… | Clinical neurophysiology : official journal of the Int… 2026-08-13 14:20:34 | Source |
| Determination of nanostructured human serum albumin assembly based on… Non-active stimulation · PMID 42070407 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source In this Research work it was evaluated different light pathways occurred through Nano-Bio-Optic coupling developed by j… | Spectrochimica acta. Part A, Molecular and biomolecula… 2026-08-13 14:20:33 | Source |
| Effect of physical activity on paired-pulse suppression in the somato… Non-active stimulation · PMID 42347861 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source Paired-pulse somatosensory evoked potentials (ppSEPs) offer a robust, non-invasive measure of inhibitory interactions i… | Experimental brain research 2026-08-13 14:20:33 | Source |
| Efficacy of a high-frequency repetitive transcranial magnetic stimula… Active stimulation · PMID 42572071 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source With the widespread popularity of online gaming, gaming addiction has come under scrutiny. While there is ongoing resea… | European archives of psychiatry and clinical neuroscie… 2026-08-13 14:20:32 | Source |
| Observed changes in clinical proxy measures of airway protection afte… Active stimulation · PMID 42564086 | Sclérose latérale amyotrophique | À vérifier | Publication | PubMed | Voir la publication source Although spinal cord stimulation (SCS) has been investigated for cough and respiratory motor output after neurological… | Frontiers in neurology 2026-08-13 14:20:32 | Source |
| Associations between lifestyle factors and 2.5-year clinical outcomes… RehaMS — Exercise Therapy in Multiple Sclerosis · PMID 42573837 | Sclérose en plaques | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Healthy lifestyle factors are associated with better health outcomes in people with multiple sclerosis (pwMS). Whether… | Neurological sciences : official journal of the Italia… 2026-08-13 14:20:31 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||