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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Intravaginal Formulation Strategies for Vaginal Disorders: Optimizing… Acupuncture · PMID 42588524 | Maladie rénale chronique · Migraine · Myopathies · Migraine · Myopath… | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Recurrent vaginal disorders remain a significant clinical challenge despite available antimicrobial and hormonal therap… | Molecules (Basel, Switzerland) 2026-08-13 14:47:16 | Source |
| Botulinum Neurotoxin Treatment of Camptocormia- A Critical Review and… OnabotulinumtoxinA · PMID 42569510 | Maladie de Parkinson · Myopathies | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Camptocormia is a disabling postural disorder characterized by involuntary forward flexion of the thoracolumbar spine t… | Tremor and other hyperkinetic movements (New York, N.Y… 2026-08-13 14:47:13 | Source |
| Health-Related Quality of Life Following Botulinum Toxin for Retrogra… OnabotulinumtoxinA · PMID 42572920 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Retrograde cricopharyngeus dysfunction (R-CPD) is a form of cricopharyngeal achalasia in which the inability to burp le… | The Laryngoscope 2026-08-13 14:47:13 | Source |
| Painful neuromas exhibit axonal phenotypic shift via nociceptive and… Calcitonin Gene-Related Peptide · PMID 42582843 | Migraine | Neuroprotection · Traitement symptomatique | Publication | PubMed | Voir la publication source Neuropathic pain encompasses a spectrum of conditions that significantly impact quality of life. In case of nerve injur… | PNAS nexus 2026-08-13 14:47:07 | Source |
| Papilledema is not the point: intracranial pressure dysregulation as… Calcitonin Gene-Related Peptide · PMID 42582597 | Hypertension artérielle · Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Accumulating evidence challenges the traditional distinction between migraine and idiopathic intracranial hypertension… | Brain communications 2026-08-13 14:47:07 | Source |
| Beyond GLP-1: Amylin-Based Pharmacotherapy and the Search for Better-… Amylin · PMID 42586227 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Amylin-based pharmacotherapy has re-emerged as a promising strategy for the treatment of obesity and metabolic disease… | Pharmacological research 2026-08-13 14:47:01 | Source |
| Digestive Hormones and Their Impact on Bariatric and Pharmacologic We… Amylin · PMID 42584007 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Obesity is a growing global health challenge associated with major cardiometabolic complications. While bariatric surge… | Endocrine reviews 2026-08-13 14:47:01 | Source |
| The Liver-Heart Axis in Rheumatoid Arthritis: Associations of Liver F… Endothelin-1 · PMID 42589498 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Liver involvement is frequent in rheumatoid arthritis (RA) and may progress from steatosis to fibrosis, cirrhosis, or h… | International journal of molecular sciences 2026-08-13 14:47:00 | Source |
| Antiseizure medication use in pregnancy and the risk of poor fetal gr… topiramate · PMID 42586099 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Poor fetal growth is a major cause of perinatal morbidity and mortality and predisposes individuals to chronic diseases… | The Lancet. Neurology 2026-08-13 14:46:52 | Source |
| EMG-guided Onabotulinum Toxin A for provoked vestibulodynia: addressi… Onabotulinum toxin A · PMID 42575277 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | American journal of obstetrics and gynecology 2026-08-13 14:46:52 | Source |
| Systemic Medications as Triggers of Acute Angle-Closure Glaucoma: A N… topiramate · PMID 42589938 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Acute angle-closure glaucoma (AACG) is an emergency requiring rapid intervention to prevent irreversible optic nerve da… | Journal of clinical medicine 2026-08-13 14:46:52 | Source |
| In-Ear Transcranial Alternating Current Stimulation: Auditory Percept… DC Stimulator (Transcranial Direct Current Stimulator) · PMID 42573546 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Noninvasive transcranial alternating current stimulation (tACS) of the cochlea might be a promising new therapeutic opt… | Neuromodulation : journal of the International Neuromo… 2026-08-13 14:46:48 | Source |
| Remotely Supervised Home-Based tDCS in Treatment-Resistant Depression… DC Stimulator (Transcranial Direct Current Stimulator) · PMID 42580014 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Remotely supervised home-based transcranial direct current stimulation (HB-tDCS) may expand access to neuromodulation f… | Psychiatry research 2026-08-13 14:46:48 | Source |
| Ultrasound-Guided Greater Occipital Nerve Pulsed Radiofrequency for C… Greater occipital nerve radiofrequency · PMID 42574205 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Managing chronic headache in older adults is complicated by multimorbidity and polypharmacy. This study evaluated 6-mon… | Annals of Indian Academy of Neurology 2026-08-13 14:46:46 | Source |
| Phosphodiesterase Type 5 Inhibitors as Chemical Hazards in Honey and… Sildenafil · PMID 42588529 | Migraine · Myopathies · Myopathies · Migraine | À vérifier | Publication | PubMed | Voir la publication source The processing of bee products has recently become more frequent due to the rapidly growing market and demand for healt… | Molecules (Basel, Switzerland) 2026-08-13 14:46:43 | Source |
| Sildenafil Positivity and Chronic Cardiac Pathology in Men Who Died o… Sildenafil · PMID 42587637 | Insuffisance cardiaque · Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Erectile dysfunction and cardiovascular disease share common pathophysiological mechanisms, yet little is known about t… | Diagnostics (Basel, Switzerland) 2026-08-13 14:46:43 | Source |
| How Common Is Hypercortisolism in Patients With Type 2 Diabetes? Risk… dexamethasone · PMID 42591054 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Hypercortisolism is an underdiagnosed contributor to metabolic dysfunction in people with Type 2 diabetes (T2D). Althou… | Diabetes, obesity & metabolism 2026-08-13 14:46:42 | Source |
| Prevention of Sleep Apnoea After General Anaesthesia Using a Thermopl… dexamethasone · PMID 42590144 | Cancer · Migraine · Myopathies · Sclérose en plaques | Thérapie génique | Publication | PubMed | Voir la publication source Sleep apnoea is associated with increased postoperative morbidity and worsens after surgery under general anaesthesia.… | Journal of clinical medicine 2026-08-13 14:46:42 | Source |
| Short-term quantitative ultrasonographic assessment of masseter muscl… Botulinum toxin type A · PMID 42579291 | Migraine · Myopathies · Myopathies · Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source To evaluate short-term clinical and ultrasonographic changes in the masseter muscle following botulinum toxin type A (B… | Cranio : the journal of craniomandibular practice 2026-08-13 14:46:38 | Source |
| The STIIM UP Protocol: Exploratory Evaluation of the Potential of Com… Botulinum toxin type A · PMID 42590155 | Migraine · Myopathies · Myopathies · Migraine | À vérifier | Publication | PubMed | Voir la publication source Cervical integument aging is a complex, multifactorial process characterized by thinning dermis, loss of elasticity, an… | Journal of clinical medicine 2026-08-13 14:46:37 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||