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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Key genetic biomarkers and therapeutic potential in multiple sclerosi… Doxorubicin Hydrochloride · PMID 42585774 | Sclérose en plaques | Immunomodulation | Publication | PubMed | Voir la publication source Multiple sclerosis (MS) is a chronic autoimmune disorder of the central nervous system characterized by inflammation, d… | Computational biology and chemistry 2026-08-13 14:47:50 | Source |
| Impact of Bevacizumab Relative Dose Intensity and Treatment-Induced P… Bevacizumab · PMID 42588647 | Cancer | Ralentissement de la progression | Publication | PubMed | Voir la publication source : Trifluridine/tipiracil (FTD/TPI) combined with bevacizumab (Bev) is an established later-line therapy for metastatic… | Cancers 2026-08-13 14:47:48 | Source |
| Delivery of Mitoxantrone by Biodegradable Cobalt-Doped Hollow Prussia… Tumor Microenvironment · PMID 42591056 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Immunotherapy has revolutionized antitumor treatment, but its effectiveness is severely compromised by the immunosuppre… | Small (Weinheim an der Bergstrasse, Germany) 2026-08-13 14:47:47 | Source |
| Immunotherapy Resistance in dMMR/MSI-H Colorectal Cancer: Unraveling… Tumor Microenvironment · PMID 42590903 | Cancer | Immunomodulation | Publication | PubMed | Voir la publication source Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide. Approximately 15% of localized a… | Journal of immunology research 2026-08-13 14:47:47 | Source |
| Interplay of Epigenetic Reprogramming, Mitochondrial Metabolism, and… ONC201 · PMID 42512251 | Cancer | Remyélinisation indirecte / réparation · Thérapie cellulaire | Publication | PubMed | Voir la publication source Diffuse midline glioma (DMG) is one of the most aggressive paediatric brain tumours and remains almost universally fata… | Cancers 2026-08-13 14:47:44 | Source |
| Molecular Tumor Board: H3K27M Diffuse Midline Glioma Diagnosed During… ONC201 · PMID 42485269 | Cancer | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Diffuse midline glioma (DMG) with the H3K27M mutation is an aggressive WHO grade 4 central nervous system tumor charact… | The oncologist 2026-08-13 14:47:44 | Source |
| Diagnostic performance of Kaiser score, ADC, and their combination fo… MRI in Ductal Carcinoma in Situ (DCIS) · PMID 42564113 | Cancer | À vérifier | Publication | PubMed | Voir la publication source The Kaiser score and apparent diffusion coefficient (ADC) have been proposed as diagnostic adjuncts to reduce unnecessa… | Frontiers in oncology 2026-08-13 14:47:43 | Source |
| Reassessing Bone Marrow Aspirate and Trephine Biopsies in Staging for… Positron Emission Tomography · PMID 42590965 | Cancer · Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source Ewing sarcoma (ES) and rhabdomyosarcoma (RMS) are aggressive malignancies in children and adolescents where metastases… | Pediatric blood & cancer 2026-08-13 14:47:41 | Source |
| Evaluation of The Use of Hydroxyurea in Treating Children With Sickle… hydroxyurea · PMID 42577886 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Sickle cell anemia (SCA) is highly prevalent in Central Africa. This disease causes severe manifestations in children,… | EJHaem 2026-08-13 14:47:39 | Source |
| Mechanisms of Hydroxyurea-Mediated DNA Damage Potentiation in Fanconi… hydroxyurea · PMID 42589438 | Cancer | Thérapie génique | Publication | PubMed | Voir la publication source Fanconi anemia (FA) is a rare disease with a deficient homologous recombination DNA repair pathway and high sensitivity… | International journal of molecular sciences 2026-08-13 14:47:39 | Source |
| Current Approaches and Emerging Strategies in the Treatment of Perito… radiation therapy · PMID 42589281 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Peritoneal carcinomatosis (PC) is a common, prognostically unfavorable manifestation of advanced gastrointestinal and g… | International journal of molecular sciences 2026-08-13 14:47:36 | Source |
| Patients with cardiac implantable electronic devices undergoing radia… radiation therapy · PMID 42590958 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Kardiologia polska 2026-08-13 14:47:36 | Source |
| Efficacy and Safety of Sintilimab in Combination With Anlotinib and C… paclitaxel albumin-stabilized nanoparticle formulation · PMID 42571169 | Cancer | Ralentissement de la progression | Publication | PubMed | Voir la publication source This study aimed to evaluate the efficacy and safety of sintilimab combined with anlotinib and chemoradiotherapy as fir… | Dose-response : a publication of International Hormesi… 2026-08-13 14:47:34 | Source |
| Prospective evaluation of dynamic changes in L3 skeletal muscle index… paclitaxel albumin-stabilized nanoparticle formulation · PMID 42577049 | Cancer | À vérifier | Publication | PubMed | Voir la publication source This prospective study aimed to assess the association between dynamic changes in the L3 skeletal muscle index (L3SMI)… | Frontiers in oncology 2026-08-13 14:47:34 | Source |
| Machine Perfusion in Liver Transplantation: A Systematic Review and M… SCS · PMID 42590059 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Static cold storage (SCS) remains the conventional standard for liver graft preservation; however, ischemia-reperfusion… | Journal of clinical medicine 2026-08-13 14:47:32 | Source |
| Measurement Invariance and Psychometric Properties of the Self-Concea… SCS · PMID 42588230 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Self-concealment is associated with greater psychological distress and decreased help-seeking engagement. This study ai… | Healthcare (Basel, Switzerland) 2026-08-13 14:47:32 | Source |
| Adjunctive middle meningeal artery embolization for chronic subdural… Middle Meningeal Artery embolization · PMID 42585760 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Randomized trials suggest that adjunctive middle meningeal artery embolization (MMAE) may reduce recurrence in chronic… | Clinical neurology and neurosurgery 2026-08-13 14:47:31 | Source |
| Beyond Middle Meningeal Artery: Paradoxical Predominance Sign Predict… Middle Meningeal Artery embolization · PMID 42586762 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Middle meningeal artery embolization (MMAE) is an emerging treatment for chronic subdural hematoma (CSDH). However, hem… | AJNR. American journal of neuroradiology 2026-08-13 14:47:31 | Source |
| Innovations in conservative and surgical therapy for Ménière's diseas… Rimegepant · PMID 42582108 | Migraine | Neuroprotection · Traitement symptomatique | Publication | PubMed | Voir la publication source Ménière's disease (MD) is an inner ear disorder of poorly understood etiology, and its management remains symptomatic.… | Frontiers in neurology 2026-08-13 14:47:19 | Source |
| Effectiveness and Safety of Herbal Decoctions for Functional Dyspepsi… Acupuncture · PMID 42588407 | Maladie rénale chronique · Migraine · Myopathies · Migraine · Myopath… | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source : Functional dyspepsia (FD) is frequently treated in Korean Medicine (KM) clinics in South Korea. With the recent inclu… | Healthcare (Basel, Switzerland) 2026-08-13 14:47:16 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||