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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Maternal Thyroid Dysfunction During Pregnancy and Childhood Autism or… Blood sample · PMID 42590824 | Lupus · Myopathies · Sclérose en plaques · Lupus · Sclérose en plaque… | Thérapie génique | Publication | PubMed | Voir la publication source Overt maternal hypothyroidism during pregnancy has been associated with cognitive impairment in offspring, but less is… | Autism research : official journal of the Internationa… 2026-08-13 14:59:58 | Source |
| Peripheral Blood Neutrophil-Monocyte-to-Lymphocyte Ratio and Long-Ter… Blood sample · PMID 42588399 | Lupus · Myopathies · Sclérose en plaques · Lupus · Sclérose en plaque… | Ralentissement de la progression · Immunomodulation · Traitement symptomatique… | Publication | PubMed | Voir la publication source Chronic obstructive pulmonary disease (COPD) is a heterogeneous syndrome with substantial variability in clinical progr… | Healthcare (Basel, Switzerland) 2026-08-13 14:59:58 | Source |
| Real-World Effectiveness of Tezepelumab Across T2 and Non-T2 Severe A… oral Prednisone 5mg · PMID 42342535 | Lupus | À vérifier | Publication | PubMed | Voir la publication source To evaluate real-world effectiveness of tezepelumab in severe asthma, by type-2 (T2) status and prior biologic exposure… | Archivos de bronconeumologia 2026-08-13 14:59:58 | Source |
| Dynamics of in vivo immune remodeling in Ph all patients receiving fr… Blinatumomab · PMID 42581034 | Cancer · Lupus · Myasthénie · Sclérose en plaques · Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Blood cancer journal 2026-08-13 14:59:55 | Source |
| Fatal Neuroinvasive Astrovirus VA1 Encephalitis in a Child With High-… Blinatumomab · PMID 42590950 | Cancer · Lupus · Myasthénie · Sclérose en plaques · Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Pediatric blood & cancer 2026-08-13 14:59:55 | Source |
| The Role of Emotions in Health Literacy and Patient Education: Trends… Educational materials · PMID 42588392 | Lupus | Thérapie génique | Publication | PubMed | Voir la publication source Health literacy and patient education play a key role in supporting informed decision-making, treatment adherence, and… | Healthcare (Basel, Switzerland) 2026-08-13 14:59:55 | Source |
| Using the Collective Impact Model to Organize Evidence-Based Programs… Educational materials · PMID 42588305 | Lupus | Ralentissement de la progression | Publication | PubMed | Voir la publication source Individuals with intellectual and/or developmental disabilities (IDDs) experience persistent health inequities, exacerb… | Healthcare (Basel, Switzerland) 2026-08-13 14:59:55 | Source |
| Achievement of real-world adapted DORIS remission targets among patie… standard therapy · PMID 42583764 | Lupus | À vérifier | Publication | PubMed | Voir la publication source IntroductionRemission is a key treatment goal associated with improved patient outcomes in systemic lupus erythematosus… | Lupus 2026-08-13 14:59:53 | Source |
| Peptide-Based Nanocomplexes Enable Transferrin-Mediated Uptake and p5… standard therapy · PMID 42589514 | Lupus | À vérifier | Publication | PubMed | Voir la publication source Glioblastoma (GB), the most prevalent and aggressive brain tumor, remains one of the most lethal challenges in modern o… | International journal of molecular sciences 2026-08-13 14:59:53 | Source |
| Case Report: Telitacicept in the treatment of refractory juvenile idi… Telitacicept · PMID 42582370 | Lupus · Myasthénie · Lupus · Myasthénie | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Refractory juvenile idiopathic arthritis (JIA) remains difficult to manage, particularly in patients with persistent di… | Frontiers in pediatrics 2026-08-13 14:59:52 | Source |
| Efficacy and safety of BAFF/APRIL-pathway inhibitors versus placebo i… Telitacicept · PMID 42587279 | Lupus · Myasthénie · Lupus · Myasthénie | À vérifier | Publication | PubMed | Voir la publication source B-cell activating factor (BAFF) and a proliferation-inducing ligand (APRIL) drive the galactose-deficient IgA1 (Gd-IgA1… | BMC nephrology 2026-08-13 14:59:52 | Source |
| Comparative Protective Effects of Anakinra and Tocilizumab in Experim… Tocilizumab · PMID 42589680 | Accident vasculaire cérébral · Cancer · Épilepsie · Lupus · Accident… | Neuroprotection · Immunomodulation | Publication | PubMed | Voir la publication source Ocular ischemic syndrome (OIS) is a vision-threatening disorder characterized by retinal ischemia, oxidative stress, an… | International journal of molecular sciences 2026-08-13 14:59:51 | Source |
| Correction: Zhao et al. Artesunate Inhibits Metastatic Potential in C… Artesunate · PMID 42587837 | Cancer | Traitement symptomatique | Publication | PubMed | Voir la publication source To better reflect the first two authors' contributions in the original article [...]. | Cells 2026-08-13 14:59:49 | Source |
| Integrated Bioinformatics Analysis Identifies FCER1G, IL1R2, and BST1… Artesunate · PMID 42590911 | Lupus | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Sepsis remains difficult to diagnose since blood culture has low sensitivity and current biomarkers lack sufficient spe… | Journal of clinical laboratory analysis 2026-08-13 14:59:49 | Source |
| Unable to walk or eat without assistance in pregnancy-Wilson's diseas… Pregnancy and Medically Assisted Conception in Rare Diseases · PMID 42527939 | Lupus | Traitement symptomatique | Publication | PubMed | Voir la publication source Wilson's disease, an autosomal recessive disorder, affects body copper metabolism. It can be fatal if left untreated as… | Journal of medical case reports 2026-08-13 14:59:46 | Source |
| Iron overload cardiomyopathy. MRI, Venipuncture · PMID 42566087 | Insuffisance cardiaque | Remyélinisation indirecte / réparation · Neuroprotection · Thérapie génique | Publication | PubMed | Voir la publication source Iron overload cardiomyopathy (IOC) remains an important cause of morbidity and mortality in patients with hereditary ha… | Heart failure reviews 2026-08-13 14:59:44 | Source |
| Secondary polycythemia as a rare cause of ischemic stroke: A case rep… MRI, Venipuncture · PMID 42491235 | Hypertension artérielle · Accident vasculaire cérébral | Traitement symptomatique | Publication | PubMed | Voir la publication source Polycythemia is a known but underrecognized risk factor for ischemic stroke, particularly in the setting of chronic hyp… | Radiology case reports 2026-08-13 14:59:44 | Source |
| Atorvastatin Mitigates Hypercholesterolemia-Induced Alterations in Ce… Atorvastatin · PMID 42589447 | Accident vasculaire cérébral · Lupus · Lupus | Remyélinisation indirecte / réparation | Publication | PubMed | Voir la publication source Statins are widely used lipid-lowering agents for the prevention and treatment of cardiovascular disease. Atorvastatin,… | International journal of molecular sciences 2026-08-13 14:59:43 | Source |
| Comparative Effects of Different Statin Regimens on Postoperative Out… Atorvastatin · PMID 42590161 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source This study aimed to evaluate the impact of various preoperative statin types and dosage regimens on early postoperative… | Journal of clinical medicine 2026-08-13 14:59:43 | Source |
| Galectin-3 in systemic lupus erythematosus: a meta-analysis. Assessment of Blood Indices in Systemic Lupus Erythematosus · PMID 42579193 | Lupus | À vérifier | Publication | PubMed | Voir la publication source This study aims to assess the circulating galectin-3 (Gal-3) levels in patients with systemic lupus erythematosus (SLE)… | Immunologic research 2026-08-13 14:59:42 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||