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Périmètre
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Chaque choix s’applique immédiatement aux quatre sections. Le filtre « type de SEP » n’apparaît que lorsque la sclérose en plaques est sélectionnée.
10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Seizure outcomes of sEEG-guided surgery for temporal vs. extratempora… SEEG monitoring · PMID 42208392 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source This study aimed to compare seizure outcomes in pediatric patients with drug-resistant epilepsy (DRE) between temporal… | Epilepsy & behavior : E&B 2026-10-04 04:36:31 | Source |
| The value of fast ripples in identifying extra-temporal epileptogenic… SEEG monitoring · PMID 42308696 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source To investigate the value of interictal fast ripples (FRs; 250-500 Hz) recorded by stereoelectroencephalography (SEEG) i… | Epilepsy research 2026-10-04 04:36:31 | Source |
| Acute spinal cord injury-acquired pneumonia induces sustained lung in… Comprehensive respiratory monitoring · PMID 42575413 | Épilepsie | Ralentissement de la progression | Publication | PubMed | Voir la publication source Systemic immunosuppression is a devastating result of spinal cord injury (SCI), leaving many patients susceptible to in… | Experimental neurology 2026-10-04 04:36:30 | Source |
| Best practices for respiratory function training in perioperative pat… Comprehensive respiratory monitoring · PMID 42472225 | Cancer | À vérifier | Publication | PubMed | Voir la publication source To identify, evaluate, and synthesize the best available evidence for respiratory function training (RFT) in perioperat… | Asia-Pacific journal of oncology nursing 2026-10-04 04:36:30 | Source |
| Effects of MC-100093, GLT-1 enhancer, in mesolimbic brain regions of… Comprehensive respiratory monitoring · PMID 42774976 | Épilepsie | Neuroprotection · Immunomodulation | Publication | PubMed | Voir la publication source Chronic exposure and overdose of opioid cause neurotoxicity through alterations of several neurotransmitters, including… | IBRO neuroscience reports 2026-10-04 04:36:30 | Source |
| High-definition transcranial random noise stimulation enhances fluid… High frequency transcranial random noise · PMID 42296988 | Maladie d’Alzheimer | À vérifier | Publication | PubMed | Voir la publication source Fluid intelligence is a core component of higher-order cognition, yet whether high-definition high-frequency transcrani… | Journal of neural engineering 2026-10-04 04:36:26 | Source |
| Occipital and parietal non-invasive brain stimulation enhances percep… High frequency transcranial random noise · PMID 42368203 | Maladie d’Alzheimer | À vérifier | Publication | PubMed | Voir la publication source Perceptual training yields specific, long-lasting improvements, yet its transfer to untrained conditions is often limit… | Frontiers in neuroscience 2026-10-04 04:36:26 | Source |
| Perceptual Learning of Multiple Object Tracking Is Not Enhanced by Tr… High frequency transcranial random noise · PMID 42345635 | Maladie d’Alzheimer | À vérifier | Publication | PubMed | Voir la publication source Multiple object tracking (MOT) assesses the ability to attentively track multiple moving targets. We investigated wheth… | Translational vision science & technology 2026-10-04 04:36:26 | Source |
| Injury risk associated with the transition to minimalist footwear in… Physiotherapy · PMID 42612386 | Maladie de Parkinson | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Running-related injuries have remained relatively stable over recent decades despite advances in athletic footwear desi… | Gait & posture 2026-10-04 04:36:20 | Source |
| Living with pain: Experiences, hopes and expectations when going thro… Physiotherapy · PMID 42821814 | Maladie de Parkinson | Traitement symptomatique | Publication | PubMed | Voir la publication source Lumbar spinal fusion (LSF) is a common surgical treatment for chronic low back pain (CLBP), yet evidence of its effecti… | International journal of qualitative studies on health… 2026-10-04 04:36:20 | Source |
| Planned gait termination in ambulatory people with multiple sclerosis… Physiotherapy · PMID 42636672 | Sclérose en plaques | Ralentissement de la progression | Publication | PubMed | Voir la publication source Gait termination (GT), the transition from steady-state walking to stable standing, requires precise deceleration and p… | Gait & posture 2026-10-04 04:36:20 | Source |
| A Systematic Review of Time and Resource Use Costs of Subcutaneous Ve… Rituximab SC · PMID 35996066 | Cancer | À vérifier | Publication | PubMed | Voir la publication source The introduction of human epidermal growth factor receptor 2 (HER2)-targeted treatment options, including dual HER2 blo… | PharmacoEconomics - open 2026-10-04 04:36:16 | Source |
| Real-World Assessment of Patient Care and Practice Efficiency With th… Rituximab SC · PMID 35089000 | Sclérose en plaques | Immunomodulation | Publication | PubMed | Voir la publication source INTRODUCTION: A subcutaneous (SC) formulation of the anti-CD20 monoclonal antibody, rituximab (Rituxan), is approved in… | Oncology (Williston Park, N.Y.) 2026-10-04 04:36:16 | Source |
| Subcutaneous rituximab in patients with diffuse large B cell lymphoma… Rituximab SC · PMID 36017743 | Sclérose en plaques | Ralentissement de la progression · Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Rituximab has become a standard treatment for non-Hodgkin lymphoma. Clinical studies have demonstrated the efficacy of… | Cancer medicine 2026-10-04 04:36:16 | Source |
| BoOFP6 Negatively Regulates Glucosinolates Accumulation in Broccoli S… B001 · PMID 41952062 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source Broccoli (Brassica oleracea L.) sprouts have been popular among consumers for its excellent nutritional value. Glucosin… | Plant, cell & environment 2026-10-04 04:36:15 | Source |
| Centrosome migration and apical membrane formation during epithelial… B001 · PMID 42708509 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source Polarization is crucial for the proper functioning of epithelial cells. Early hallmarks include the trafficking and enr… | eLife 2026-10-04 04:36:15 | Source |
| Robot‑assisted versus open radical nephrectomy and venous tumor throm… B001 · PMID 42618819 | Sclérose en plaques | Ralentissement de la progression · Thérapie génique | Publication | PubMed | Voir la publication source Open radical nephrectomy and venous thrombectomy (ORN‑VT) is standard for renal cell carcinoma with tumor thrombus (RCC… | Surgical endoscopy 2026-10-04 04:36:15 | Source |
| Effects of testosterone-augmented multimodal exercise intervention in… Whole-body Electrical Muscle Stimulation Exercise · PMID 41988780 | Myasthénie · Myopathies · Sclérose latérale amyotrophique · Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Spinal cord injury (SCI) leads to profound muscle atrophy, aerobic deconditioning, and metabolic dysfunction. Exercise-… | The Journal of clinical endocrinology and metabolism 2026-09-20 04:37:05 | Source |
| Feasibility and acceptability of whole-body electromyostimulation in… Whole-body Electrical Muscle Stimulation Exercise · PMID 42464389 | Myasthénie · Myopathies · Sclérose latérale amyotrophique · Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Evidence on the effectiveness of electromyostimulation (EMS) has been reported in pulmonary rehabilitation, but the ben… | Pilot and feasibility studies 2026-09-20 04:37:05 | Source |
| Vestibular contributions adapt to the balance strategies adopted duri… Whole-body Electrical Muscle Stimulation Exercise · PMID 42616645 | Myasthénie · Myopathies · Sclérose latérale amyotrophique · Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Vestibular contributions during walking are not uniform, but vary with gait phase, muscle group, and balance demands. M… | Journal of neurophysiology 2026-09-20 04:37:05 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||