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Périmètre

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Chaque choix s’applique immédiatement aux quatre sections. Le filtre « type de SEP » n’apparaît que lorsque la sclérose en plaques est sélectionnée.

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Essais et traitements5743Données cliniques et programmes
Recherches et trouvailles21Pipeline scientifique
Publications4871Références reliées aux maladies
Pistes exploratoires0Hypothèses non validées
10635 résultats correspondants · 41 visibles sur cette page dans le périmètre Toutes les maladies
Niveau clinique

Études et traitements 5743

Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.

Molécule / élément Maladie / population Objectif Phase / stade Statut / preuve Mécanisme / résumé Source Détail
Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… Maladie coronarienne À vérifier Non applicable NOT_YET_RECRUITING The objective of this study is to obtain experience with new and modified… À vérifier ClinicalTrials.gov 2026-11-09 21:03:06 Détail
SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… Maladie coronarienne Traitement symptomatique Non applicable NOT_YET_RECRUITING This is an early study of a catheter-based minimally invasive procedure ca… À vérifier ClinicalTrials.gov 2026-11-09 21:03:06 Détail
Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… Maladie coronarienne Thérapie génique À vérifier NOT_YET_RECRUITING In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier ClinicalTrials.gov 2026-11-09 21:03:06 Détail
Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS Maladie coronarienne Traitement symptomatique Non applicable NOT_YET_RECRUITING Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier ClinicalTrials.gov 2026-11-09 21:03:06 Détail
Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System Maladie coronarienne Traitement symptomatique Non applicable RECRUITING This early feasibility study is evaluating the safety and performance of t… À vérifier ClinicalTrials.gov 2026-11-09 21:03:05 Détail
Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… Maladie coronarienne À vérifier Phase 4 NOT_YET_RECRUITING Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier ClinicalTrials.gov 2026-11-09 21:03:05 Détail
Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… Maladie coronarienne Traitement symptomatique Non applicable RECRUITING This randomized single-blind controlled trial aims to compare the effectiv… À vérifier ClinicalTrials.gov 2026-11-09 21:03:05 Détail
Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… Maladie coronarienne À vérifier Non applicable COMPLETED Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier ClinicalTrials.gov 2026-11-09 21:03:05 Détail
Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) Maladie coronarienne Immunomodulation · Traitement symptomatique Non applicable NOT_YET_RECRUITING This pilot study will test an innovative way to establish how pain medicin… À vérifier ClinicalTrials.gov 2026-11-09 21:03:05 Détail
Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… Maladie coronarienne À vérifier Phase 3 RECRUITING In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier ClinicalTrials.gov 2026-11-09 21:03:05 Détail
Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation Maladie coronarienne Ralentissement de la progression Non applicable RECRUITING Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier ClinicalTrials.gov 2026-11-09 21:03:05 Détail
Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… Maladie coronarienne Traitement symptomatique Non applicable RECRUITING This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier ClinicalTrials.gov 2026-11-09 21:03:05 Détail
TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… Maladie coronarienne À vérifier À vérifier RECRUITING \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier ClinicalTrials.gov 2026-11-09 21:03:05 Détail
This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… Maladie coronarienne Traitement symptomatique Non applicable RECRUITING Although advances in treatment and patient management have considerably im… À vérifier ClinicalTrials.gov 2026-11-09 21:03:05 Détail
Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction Maladie coronarienne À vérifier Phase 4 ACTIVE_NOT_RECRUITING The primary objective of this study is to evaluate the effectiveness of ea… À vérifier ClinicalTrials.gov 2026-11-09 21:03:04 Détail
Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… Maladie coronarienne Thérapie génique Non applicable RECRUITING The goal of this clinical trial is to learn which treatment strategies imp… À vérifier ClinicalTrials.gov 2026-11-09 21:03:04 Détail
No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… Maladie coronarienne À vérifier Phase 4 COMPLETED The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier ClinicalTrials.gov 2026-11-09 21:03:04 Détail
Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm Maladie coronarienne À vérifier Non applicable RECRUITING This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier ClinicalTrials.gov 2026-11-09 21:03:04 Détail
26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… Myopathies Traitement symptomatique Non applicable NOT_YET_RECRUITING This randomized split-face study aims to compare the effects of 26G and 30… À vérifier ClinicalTrials.gov 2026-11-09 21:02:59 Détail
ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… Myopathies À vérifier Phase 1 RECRUITING This is an open-label phase 1 study to determine the safety and tolebility… À vérifier ClinicalTrials.gov 2026-11-09 21:02:59 Détail
Découverte scientifique

Recherches et trouvailles 21

Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.

Molécule / élément Maladie / population Objectif Phase / stade Statut / preuve Mécanisme / résumé Source Détail
4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation Sclérose latérale amyotrophique Neuroprotection · Immunomodulation Découverte fondamentale Exploratoire Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… Revue scientifique 2024-07-01 Détail
Bibliographie

Publications 4871

Références bibliographiques de la base locale et accès à leur source originale.

Molécule / élément Maladie / population Objectif Phase / stade Statut / preuve Mécanisme / résumé Source Détail
Positional release technique in the management of low back pain: A sy… Positional Release Technique · PMID 40954594 Myopathies Traitement symptomatique Publication PubMed Voir la publication source This systematic review aimed to evaluate the effects of positional release technique (PRT) on clinically relevant outco… Journal of bodywork and movement therapies 2026-08-13 15:03:00 Source
Positional Release Technique Versus Muscle Energy Technique for Patie… Positional Release Technique · PMID 41873799 Myopathies Ralentissement de la progression · Traitement symptomatique Publication PubMed Voir la publication source This study, being a pilot research, explored the comparative short-term results, as well as the feasibility, of using p… Pain research & management 2026-08-13 15:03:00 Source
Gene therapy in Duchenne muscular dystrophy. SGT-003 · PMID 41391912 Myopathies Thérapie génique Publication PubMed Voir la publication source Duchenne muscular dystrophy (DMD) is a severe X-linked myopathy caused by mutations in the DMD gene, resulting in the a… Archives de pediatrie : organe officiel de la Societe… 2026-08-13 15:02:59 Source
Effects of connective tissue massage and kinesiotaping in patients wi… KinesioTape — The Effect of KT on Tissue Parameters · PMID 39593407 Myopathies Traitement symptomatique Publication PubMed Voir la publication source Fibromyalgia (FM) is a common soft tissue rheumatic disease. There is no established treatment plan for FM. Current tre… Journal of bodywork and movement therapies 2026-08-13 15:02:58 Source
Effects of tape and Kinesiotape on ankle range of motion, Single Leg… KinesioTape — The Effect of KT on Tissue Parameters · PMID 40258080 Myopathies Traitement symptomatique Publication PubMed Voir la publication source The prevention and management of injuries in runners is a key area of research in sports medicine. Fatigue during runni… PloS one 2026-08-13 15:02:58 Source
Clinical Use of Interleukin-6 Blockade in Neuroimmunological Disorder… Satralizumab · PMID 42583026 Maladie d’Alzheimer · Sclérose en plaques Remyélinisation · Neuroprotection · Immunomodulation Publication PubMed Voir la publication source Interleukin-6 (IL-6) is a multifunctional cytokine that plays a critical role in immune regulation, host defense, and t… Noro psikiyatri arsivi 2026-08-13 15:02:57 Source
Reduced drug use and hospitalization rates in patients undergoing hem… Impact of Clinical Pharmacy Services on Medication Cost and Hospitalization Rates in Hemodialy… Myopathies À vérifier Publication PubMed Voir la publication source To investigate the impact of a pharmaceutical care program managed by clinical pharmacists on drug use, drug costs, hos… Pharmacotherapy 2026-08-13 15:02:53 Source
Current practice and guideline adherence in renal dose adjustment for… AB-1003 dose level 2 · PMID 42590882 Maladie rénale chronique À vérifier Publication PubMed Voir la publication source To quantify prescribing adherence to renal dosing recommendations in adults with chronic kidney disease (CKD; Stage 3 a… British journal of clinical pharmacology 2026-08-13 15:02:51 Source
Anticoagulation Stewardship in the Era of Practice-Changing Evidence:… AB-1003 dose level 1 · PMID 42590048 Cancer À vérifier Publication PubMed Voir la publication source The evidence base for anticoagulation moved substantially between 2023 and 2026: a reframed atrial fibrillation (AF) gu… Journal of clinical medicine 2026-08-13 15:02:50 Source
Hyperkalemia Risk After Finerenone Initiation in Diabetic Kidney Dise… AB-1003 dose level 1 · PMID 42589862 Myopathies À vérifier Publication PubMed Voir la publication source : Finerenone improves cardiovascular and renal outcomes in diabetic kidney disease (DKD), but hyperkalemia remains a ke… Journal of clinical medicine 2026-08-13 15:02:50 Source
Liver health in myotubular and centronuclear myopathies: a patient-dr… CMDPROS — Congenital Muscle Disease Study of Patient and Family Reported Medical Information ·… Myopathies Traitement symptomatique Publication PubMed Voir la publication source Liver health issues in X-linked myotubular myopathy and centronuclear myopathies have historically been under-recognize… Neuromuscular disorders : NMD 2026-08-13 15:02:49 Source
Six novel SACS mutations expand the autosomal recessive spastic ataxi… CMDPROS — Congenital Muscle Disease Study of Patient and Family Reported Medical Information ·… Myopathies Traitement symptomatique Publication PubMed Voir la publication source BACKGROUND: The clinical spectrum of autosomal recessive spastic ataxia of Charlevoix–Saguenay (ARSACS) in Asian popula… Orphanet journal of rare diseases 2026-08-13 15:02:49 Source
Neuromorphic Devices and Computing for Sensing, Memory, and Control. Stem Cell · PMID 42591065 Myopathies Thérapie cellulaire Publication PubMed Voir la publication source Neuromorphic devices are bioinspired electronic systems that mimic key structures and functions of the nervous system,… Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026-08-13 15:02:48 Source
Effect of Instrument-Assisted Soft Tissue Mobilization Combined With… Effect of Phonophoresis on Trigger Points · PMID 41206797 Myopathies Ralentissement de la progression · Traitement symptomatique Publication PubMed Voir la publication source The purpose of this study was to investigate the effects of instrument-assisted soft tissue mobilization (IASTM) and li… Journal of manipulative and physiological therapeutics 2026-08-13 15:02:47 Source
Platelet rich plasma therapy versus other modalities for treatment of… Effect of Phonophoresis on Trigger Points · PMID 38395675 Myopathies Traitement symptomatique Publication PubMed Voir la publication source Plantar fasciitis (PF) is the most common cause of heel pain in adults. There are numerous non-operative treatments ava… Foot and ankle surgery : official journal of the Europ… 2026-08-13 15:02:47 Source
Clinical effect of kinesio taping combined with dry needling to myofa… Dry Needling for Myofascial Pain Syndrome · PMID 42545155 Accident vasculaire cérébral Ralentissement de la progression · Traitement symptomatique Publication PubMed Voir la publication source Shoulder-hand syndrome (SHS) is a common complication after stroke, characterized by pain, edema, and functional impair… European journal of physical and rehabilitation medici… 2026-08-13 15:02:46 Source
Comparative effects of low-level laser acupuncture and dry needling o… Dry Needling for Myofascial Pain Syndrome · PMID 42430011 Myopathies Ralentissement de la progression · Traitement symptomatique Publication PubMed Voir la publication source The purpose of this study was to compare the effectiveness of Low-Level Laser Acupuncture with Dry Needling along with… Lasers in medical science 2026-08-13 15:02:46 Source
Physical therapy interventions for awake and sleep bruxism: What has… Splint Therapy · PMID 42497348 Myopathies Ralentissement de la progression · Traitement symptomatique Publication PubMed Voir la publication source The objective of this systematic review was to summarize the physiotherapy (PT) treatments used over the last few decad… Dental and medical problems 2026-08-13 15:02:45 Source
Volume of Treatment of Temporomandibular Disorders in Adults-A Nation… Splint Therapy · PMID 42449475 Myopathies Traitement symptomatique Publication PubMed Voir la publication source Temporomandibular disorders (TMD) present diverse signs and symptoms and often require clinical evaluation. To investig… Journal of oral rehabilitation 2026-08-13 15:02:45 Source
A Phase 1, Double-Blind, Placebo-Controlled Trial of Sevasemten (EDG-… Sevasemten Dose 2 · PMID 40452637 Myopathies À vérifier Publication PubMed Voir la publication source Sevasemten (EDG-5506) is an orally administered, investigational small molecule that selectively modulates fast muscle… Muscle & nerve 2026-08-13 15:02:43 Source
Exploration — prudence

Pistes exploratoires 0

Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.

Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
Molécule / élément Maladie / population Objectif Phase / stade Statut / preuve Mécanisme / résumé Source Détail
Aucune piste exploratoire ne correspond aux filtres.