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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Evaluation of influenza vaccine effectiveness among older adults in J… Influenza Vaccine · PMID 42202217 | Sclérose en plaques | Traitement symptomatique | Publication | PubMed | Voir la publication source Influenza imposes a substantial burden on older adults, underscoring the need for annual evaluation of vaccine effectiv… | Human vaccines & immunotherapeutics 2026-08-16 13:05:07 | Source |
| Harnessing Secondary Nucleation-Driven Supramolecular Bundled Fibers… KLH · PMID 42578607 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source Achieving long-range 1D organization of semiconductor nanocrystals without altering their inherent optical properties i… | Angewandte Chemie (International ed. in English) 2026-08-16 13:05:07 | Source |
| HPV vaccination scenario and parental willingness to pay among girls… Influenza Vaccine · PMID 42228981 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source Human papillomavirus (HPV) vaccine uptake remains suboptimal among adolescent girls in China. In November 2025, bivalen… | Human vaccines & immunotherapeutics 2026-08-16 13:05:07 | Source |
| Sinomenine restrains the proliferation and hyperactivation of B lymph… KLH · PMID 42288163 | Lupus | Immunomodulation | Publication | PubMed | Voir la publication source B lymphocytes are central drivers of pathogenic immune responses in autoimmune diseases and represent a promising targe… | Journal of ethnopharmacology 2026-08-16 13:05:07 | Source |
| 8-year vaccine protection following a single dose of Vi-tetanus toxoi… 13-PCV Booster · PMID 42575113 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source In low-income and middle-income countries, where typhoid fever remains a major public health problem, WHO recommends th… | The Lancet. Global health 2026-08-16 13:05:06 | Source |
| Effect of probiotics on humoral responses to COVID-19 vaccination in… 13-PCV Booster · PMID 42520140 | Sclérose en plaques | Thérapie génique | Publication | PubMed | Voir la publication source Although COVID-19 vaccination has reduced morbidity and mortality, adults aged 65 y old and older are at high risk of c… | Gut microbes 2026-08-16 13:05:06 | Source |
| Parental preferences for immunization advisory clinic settings for ch… 13-PCV Booster · PMID 42547995 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source Children with special health care needs (CSHCN) face persistent immunization inequity despite high overall childhood va… | Human vaccines & immunotherapeutics 2026-08-16 13:05:06 | Source |
| Cost-Utility Analysis of Early Vitrectomy vs Intravitreal Biopsy and… 23-PPV · PMID 40919299 | Sclérose en plaques | À vérifier | Publication | PubMed | Voir la publication source To perform a cost-utility analysis comparing primary pars-plana vitrectomy (PPV) within 24 hours with primary nonsurgic… | Journal of vitreoretinal diseases 2026-08-16 13:05:05 | Source |
| Evaluating the Diagnostic Accuracy of Point-of-Care Ultrasound for Lo… 23-PPV · PMID 41945995 | Sclérose en plaques | Thérapie génique | Publication | PubMed | Voir la publication source Long bone fractures are a common emergency department presentation. Conventional radiography, though standard, is limit… | The Journal of emergency medicine 2026-08-16 13:05:05 | Source |
| Early posttransplant rituximab use in kidney transplant recipients wi… Anti-CD20 antibody · PMID 41582011 | Sclérose en plaques | Immunomodulation | Publication | PubMed | Voir la publication source The presence of pretransplant anti-human leukocyte antigen (HLA) donor-specific antibodies (DSAs) is still a significan… | Renal failure 2026-08-16 13:05:02 | Source |
| Low-dose vemurafenib plus rituximab in frontline and relapsed or refr… Anti-CD20 antibody · PMID 42308249 | Sclérose en plaques | Ralentissement de la progression · Immunomodulation | Publication | PubMed | Voir la publication source Purine nucleoside analogs are highly effective in the treatment of hairy cell leukemia (HCL) but are associated with my… | Blood advances 2026-08-16 13:05:02 | Source |
| Quantitative Single-Cell Multielemental Analysis Using Metal-Loaded M… Anti-CD20 antibody · PMID 42503649 | Cancer | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source The use of lanthanide-tagged antibodies enables multiplexed biomarker monitoring in individual cells by mass cytometry.… | Analytical chemistry 2026-08-16 13:05:02 | Source |
| Evidence of skull bone translocator protein overexpression linked to… Pain Phenotypes in Individuals With Multiple Sclerosis · PMID 41802262 | Sclérose en plaques | Ralentissement de la progression · Immunomodulation | Publication | PubMed | Voir la publication source The skull bone marrow contributes to brain immune homeostasis via recently discovered skull-meningeal channels, enablin… | Brain : a journal of neurology 2026-08-16 13:05:00 | Source |
| Neurogenic Pelvic Floor Dysfunctions Across Neurological Disorders: M… Pain Phenotypes in Individuals With Multiple Sclerosis · PMID 42452600 | Accident vasculaire cérébral · Maladie d’Alzheimer · Maladie de Parki… | Traitement symptomatique | Publication | PubMed | Voir la publication source Pelvic floor dysfunction (PFD) is frequent in neurological disorders, but it is often approached as a secondary urologi… | Journal of clinical medicine 2026-08-16 13:05:00 | Source |
| Neuropathic pain in multiple sclerosis: discrepancies between DN4 scr… Pain Phenotypes in Individuals With Multiple Sclerosis · PMID 42263353 | Sclérose en plaques | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Pain is a common and disabling symptom in multiple sclerosis (MS), yet its pathophysiological mechanisms remain poorly… | Multiple sclerosis and related disorders 2026-08-16 13:05:00 | Source |
| Effect of intensive blood pressure and blood glucose control on cardi… Indapamide · PMID 42056835 | Maladie coronarienne · Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source This study aims to re-analyse the ADVANCE (Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Rel… | European heart journal. Cardiovascular pharmacotherapy 2026-08-16 13:04:59 | Source |
| Real-World Effectiveness and Safety of Ramipril/Indapamide Combinatio… Indapamide · PMID 42453630 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source This study aimed to evaluate the patient characteristics, effectiveness, safety, adherence, and persistence of ramipril… | International journal of hypertension 2026-08-16 13:04:59 | Source |
| Fin-Ray soft gripper for object manipulation with multi-robot systems. SetPoint System · PMID 42519107 | Sclérose en plaques | Thérapie génique | Publication | PubMed | Voir la publication source Soft robotic grippers are attractive for cooperative object transport in multi-robot systems because they tolerate posi… | HardwareX 2026-08-16 13:04:58 | Source |
| Fundamental questions on closed-loop neuromodulation: a control theor… SetPoint System · PMID 42109929 | Sclérose en plaques | Thérapie génique | Publication | PubMed | Voir la publication source Closed-loop neuromodulation aims to adjust therapeutic stimulation in real time based on ongoing neural or physiologica… | Cognitive neurodynamics 2026-08-16 13:04:58 | Source |
| Neurostimulation of the cholinergic anti-inflammatory pathway amelior… SetPoint Medical Neurostimulation of the Cholinergic Anti-inflammatory Pathway System · PMID 2… | Sclérose en plaques | Immunomodulation | Publication | PubMed | Voir la publication source The inflammatory reflex is a physiological mechanism through which the nervous system maintains immunologic homeostasis… | PloS one 2026-08-16 13:04:58 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||