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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ablation Treatment with FARAPULSE™ Pulsed Field Ablation (PFA) System… NCT07925359 · NAVigate-ULTRA — The Evaluation of User Experience With FARAVIEW™ Technology of… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The objective of this study is to obtain experience with new and modified… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| SESAME Procedure NCT07806149 · NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective… | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This is an early study of a catheter-based minimally invasive procedure ca… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Topical cyanoacrylate tissue adhesive NCT07926191 · Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After E… | Maladie coronarienne | Thérapie génique | À vérifier | NOT_YET_RECRUITING | In July 2026 the electrophysiology laboratory of a Czech tertiary cardiolo… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Truvaga Plus NCT07926945 · U54: nVNS RCT — Effects of nVNS on Stress Reactivity in IBS | Maladie coronarienne | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interact… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:06 | Détail |
| Capstan Compass Robotic System for Transcatheter Mitral Valve Replace… NCT07917208 · Early Feasibility Study of the Capstan Medical TMVR System | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This early feasibility study is evaluating the safety and performance of t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Discontinuation of aspirin (ATC-code B01AC06 and N02BA01) NCT07854795 · RELEASE-Norway — Reconsidering Long-Term Apirin in the Elderly in Secondary Prev… | Maladie coronarienne | À vérifier | Phase 4 | NOT_YET_RECRUITING | Lifelong aspirin has been a cornerstone of secondary prevention after coro… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Extracorporeal Shock Wave Therapy NCT07068399 · CSWT — Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronar… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized single-blind controlled trial aims to compare the effectiv… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Modified ultrafiltration NCT00246779 · A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Su… | Maladie coronarienne | À vérifier | Non applicable | COMPLETED | Cardiac surgery is a major consumer of blood products worldwide. The natur… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Naproxen NCT07549490 · Human Experimental Models of Pain (HEMP) | Maladie coronarienne | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This pilot study will test an innovative way to establish how pain medicin… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Prescription of Aspirin NCT07524335 · ASCAD-P — Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Con… | Maladie coronarienne | À vérifier | Phase 3 | RECRUITING | In patients with subclinical coronary artery disease, the ASCAD-P study ai… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Pulmonary Vein Isolation NCT06402617 · RETRO-AF — Ablation of Focal Activation in Atrial Fibrillation | Maladie coronarienne | Ralentissement de la progression | Non applicable | RECRUITING | Atrial Fibrillation (AF) and Heart Failure (HF) are colliding global cardi… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Serratus Posterior Superior Intercostal Plane Block With Bupivacaine NCT07588230 · Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardia… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | This randomized, double-blind, placebo-controlled study aims to evaluate t… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| TAVI NCT07926022 · TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patient… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | \# WHAT IS THIS STUDY ABOUT? This study compares two different treatment a… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| This study involved an auxillary CE-marked medical device (implantabl… NCT07545512 · ODISSEY — ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Car… | Maladie coronarienne | Traitement symptomatique | Non applicable | RECRUITING | Although advances in treatment and patient management have considerably im… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:05 | Détail |
| Evolocumab NCT05284747 · EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | Maladie coronarienne | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | The primary objective of this study is to evaluate the effectiveness of ea… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Microaxial flow pump (left ventricular assist device) NCT07762560 · DOUBLE-SHOCK — Routine Microaxial Heart Pump Support and Protocolized Pulmonary… | Maladie coronarienne | Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn which treatment strategies imp… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| No aspirin (Prasugurel monotherapy) NCT05709626 · PREMIUM — PRasugrEl Monotherapy Following prImary percUtaneous Coronary Interven… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | The aim of this study is to evaluate the safety of prasugrel monotherapy w… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| Percutaneous Mechanical Circulatory Support NCT06445608 · PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | This purpose of this trial is to demonstrate 30 day safety and effectivene… À vérifier | ClinicalTrials.gov 2026-11-09 21:03:04 | Détail |
| 26G Needle NCT07926113 · MASS-NEEDLE — Comparison of 26G and 30G Needles for Masseter Trigger Point Injec… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | This randomized split-face study aims to compare the effects of 26G and 30… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
| ABSK021 NCT04192344 · A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in… | Myopathies | À vérifier | Phase 1 | RECRUITING | This is an open-label phase 1 study to determine the safety and tolebility… À vérifier | ClinicalTrials.gov 2026-11-09 21:02:59 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Cardioprotective effect of the quercetin on cardiovascular remodeling… Effects of Xoçai Antioxidant Supplements on Atherosclerosis Risk Factors · PMID 37690744 | Hypertension artérielle | Neuroprotection · Ralentissement de la progression | Publication | PubMed | Voir la publication source Cardiovascular diseases (CVD) are the leading cause of death globally, estimated at 17.9 million premature deaths. Seve… | Chemico-biological interactions 2026-08-16 13:12:42 | Source |
| Durability of Blood Pressure Reduction After Renal Denervation in Res… doublepres — The Diagnosis and Treatment of Resistant Hypertension, the Prevalence and the Pro… | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Renal sympathetic denervation (RDN) has demonstrated blood pressure-lowering efficacy in randomized trials; however, lo… | Journal of clinical hypertension (Greenwich, Conn.) 2026-08-16 13:12:42 | Source |
| Favorable Effects of Renal Denervation in Hypertension-Related Comorb… doublepres — The Diagnosis and Treatment of Resistant Hypertension, the Prevalence and the Pro… | Hypertension artérielle · Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Renal denervation (RDN) according to the latest ESH guidelines can be considered as a treatment option for patients wit… | Catheterization and cardiovascular interventions : off… 2026-08-16 13:12:42 | Source |
| Multi-Omics Reveals the Effects of Cannabidiol on Gut Microbiota and… Effects of Xoçai Antioxidant Supplements on Atherosclerosis Risk Factors · PMID 37098174 | Hypertension artérielle | Thérapie génique | Publication | PubMed | Voir la publication source Cannabidiol (CBD) has important pharmacological activity, which includes antispasmodic, antioxidant, antithrombotic, an… | Cannabis and cannabinoid research 2026-08-16 13:12:42 | Source |
| Prophylactic and therapeutic effects of EsV3 on atherosclerotic lesio… Effects of Xoçai Antioxidant Supplements on Atherosclerosis Risk Factors · PMID 39865227 | Hypertension artérielle | Neuroprotection | Publication | PubMed | Voir la publication source Atherosclerosis (AS) is a major contributor to vascular disorders and represents a significant risk to human health. Cu… | BMC cardiovascular disorders 2026-08-16 13:12:42 | Source |
| Enalapril, Atenolol, Alendronate and DRESS Syndrome - A Case Report. enalapril · PMID 42593154 | Hypertension artérielle · Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Acta dermato-venereologica 2026-08-16 13:12:41 | Source |
| High-molecular-weight hyaluronic acid promotes the protective axis of… enalapril · PMID 42424931 | Hypertension artérielle · Maladie rénale chronique | Immunomodulation | Publication | PubMed | Voir la publication source Hypertrophic scar and keloids are skin conditions strongly influenced by an imbalance of the renin-angiotensin-aldoster… | Biochemical and biophysical research communications 2026-08-16 13:12:41 | Source |
| Sacubitril/Valsartan versus Enalapril or Losartan at Maximum Doses in… enalapril · PMID 42585517 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Sacubitril/valsartan reduced mortality and hospitalizations in patients with heart failure with reduced ejection fracti… | Arquivos brasileiros de cardiologia 2026-08-16 13:12:41 | Source |
| "I gave birth, and then I disappeared"-women's experience of primary… Telemedicine · PMID 42603167 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Primary care follow-up of women with previous GDM is often lacking. Little is known about effective approaches to impro… | International journal of qualitative studies on health… 2026-08-16 13:12:34 | Source |
| Canine brain imaging with a new low-field portable (0.05 T) MRI scann… Telemedicine · PMID 42444639 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Prohibitive costs associated with high-field MRI systems have resulted in reduced access in resource-limited areas with… | The veterinary quarterly 2026-08-16 13:12:34 | Source |
| Integration of cognitive behavioral therapy and mobile health applica… Telemedicine · PMID 42454530 | Hypertension artérielle | Traitement symptomatique | Publication | PubMed | Voir la publication source Most applications for depression lack comprehensive theoretical integration and qualitative assessments of university s… | International journal of qualitative studies on health… 2026-08-16 13:12:34 | Source |
| Cardiorespiratory fitness and left ventricular recovery after kidney… Magnetic Resonance Imaging for Evaluating Kidney Function · PMID 41772838 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Despite improved survival following kidney transplantation, cardiovascular disease (CVD) remains a leading cause of mor… | Renal failure 2026-08-16 13:12:32 | Source |
| Multiparametric MRI for Early Chronic Kidney Disease Detection: Insig… Magnetic Resonance Imaging for Evaluating Kidney Function · PMID 42478113 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source Chronic kidney disease (CKD) is a major health burden. Intrarenal microcirculation impairment occurs early in CKD and p… | NMR in biomedicine 2026-08-16 13:12:32 | Source |
| Navigating the diagnostic 'gray zone': prospective evaluation of an i… Magnetic Resonance Imaging for Evaluating Kidney Function · PMID 42305025 | Hypertension artérielle | Thérapie génique | Publication | PubMed | Voir la publication source A critical dilemma in post-transplant surveillance is determining when minor functional changes (subtle serum creatinin… | Annals of medicine 2026-08-16 13:12:32 | Source |
| Pseudo-Meigs syndrome owing to a retained fibroid following total lap… myoma removal · PMID 40810624 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Total laparoscopic hysterectomy (TLH) is the most common gynecologic procedure for fibroids. However, massive serous as… | International journal of gynaecology and obstetrics: t… 2026-08-16 13:12:32 | Source |
| Bibliometric analysis of sacubitril/valsartan in the management of ch… Sacubitril/valsartan · PMID 41943607 | Maladie rénale chronique | Thérapie génique | Publication | PubMed | Voir la publication source Chronic kidney disease (CKD) is a global health issue with progressive renal decline. Sacubitril-valsartan, the first a… | Renal failure 2026-08-16 13:12:29 | Source |
| Biomarker-guided pharmacotherapy in cardiovascular-kidney-metabolic s… Sacubitril/valsartan · PMID 42492739 | Hypertension artérielle | Ralentissement de la progression · Immunomodulation · Thérapie cellulaire · Thé… | Publication | PubMed | Voir la publication source Cardiovascular-kidney-metabolic (CKM) syndrome, formally defined by the American Heart Association in 2023, affects app… | Pharmacology & therapeutics 2026-08-16 13:12:29 | Source |
| Spatially resolved label-free FTIR imaging reveals compartment-specif… Sacubitril/valsartan · PMID 42456519 | Hypertension artérielle | Ralentissement de la progression | Publication | PubMed | Voir la publication source Cardiorenal syndrome (CRS) involves complex and spatially heterogeneous remodeling in both cardiac and renal tissues. C… | Spectrochimica acta. Part A, Molecular and biomolecula… 2026-08-16 13:12:29 | Source |
| A pharmacokinetic and pharmacodynamic drug interaction between rosuva… Valsartan 160 mg + Rosuvastatin 20 mg · PMID 25767372 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Valsartan, an angiotensin-receptor blocker, and rosuvastatin, a competitive inhibitor of the 3-hydroxy-3-methylglutaryl… | Drug design, development and therapy 2026-08-16 13:12:27 | Source |
| Effect of Amlodipine/Valsartan Versus Nebivolol/Valsartan Fixed Dose… Amlodipine 10 mg + Valsartan 160 mg · PMID 30390203 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Although hypertensive drugs may have the same effect on peripheral blood pressure, they vary in their effect on central… | High blood pressure & cardiovascular prevention : the… 2026-08-16 13:12:26 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||