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Toutes les maladies
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Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| QLS2319 NCT07735104 · The First in Human Study of QLS2319 in Healthy Subjects and Cancer Cachexia | Cancer | À vérifier | Phase 1/2 | RECRUITING | Study To Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodyna… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:55 | Détail |
| TAR-200 NCT06211764 · SunRISe-5 — A Study of TAR-200 Versus Intravesical Chemotherapy in Participants… | Cancer | Traitement symptomatique | Phase 3 | ACTIVE_NOT_RECRUITING | The purpose of this study is to compare disease free survival (DFS) in par… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:55 | Détail |
| Telisotuzumab Adizutecan NCT07525206 · AndroMETa-CRC — A Study to Access Intravenous (IV) Telisotuzumab Adizutecan in C… | Cancer | À vérifier | Phase 3 | RECRUITING | Non small cell lung carcinoma (NSCLC) is the most frequently occurring his… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:55 | Détail |
| XYA02 NCT07670312 · Evaluation of XYA02 in Patients With Advanced Solid Tumors | Cancer | À vérifier | Phase 1/2 | RECRUITING | This study will evaluate the safety, tolerability, and efficacy of XYA02 i… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:55 | Détail |
| Ami-LC-MD NCT04606381 · PALOMA — A Study of Amivantamab Subcutaneous (SC) Administration for the Treatme… | Cancer | À vérifier | Phase 1 | ACTIVE_NOT_RECRUITING | The purpose of this study is to assess the feasibility of subcutaneous (SC… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:54 | Détail |
| Biospecimen Collection NCT07377006 · Decision Support Tool to Enhance Germline Genetic Testing for Patients With Pros… | Cancer | À vérifier | Non applicable | RECRUITING | This phase III trial compares standard of care hormone therapy plus riboci… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:54 | Détail |
| High-dose methotrexate-based therapy NCT07842835 · Registry of an Integrated Longitudinal Multimodal Biospecimen Biobank for Primar… | Cancer | Thérapie génique | À vérifier | NOT_YET_RECRUITING | This project aims to establish and prospectively register a longitudinal,… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:54 | Détail |
| IBI3001 NCT06349408 · IBI3001 in Participants With Unresectable, Locally Advanced or Metastatic Solid… | Cancer | À vérifier | Phase 1 | RECRUITING | This is a Phase 1 multicenter, multi-regional, open-label, first-in-human… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:54 | Détail |
| JDQ443 NCT05132075 · KontRASt-02 — Study of JDQ443 in Comparison With Docetaxel in Participants With… | Cancer | À vérifier | Phase 3 | ACTIVE_NOT_RECRUITING | This is a phase III randomized open label study designed to compare JDQ443… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:54 | Détail |
| JNJ-90301900 NCT06667908 · CONVERGE — A Study of JNJ-90301900 in Combination With Chemoradiation Followed b… | Cancer | À vérifier | Phase 2 | RECRUITING | The purpose of this study is to determine whether JNJ-90301900 added to co… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:54 | Détail |
| Odronextamab NCT06091865 · OLYMPIA-3 — A Study to Compare How Well Odronextamab Combined With Chemotherapy… | Cancer | À vérifier | Phase 3 | RECRUITING | This study is researching a particular group of experimental drugs adminis… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:54 | Détail |
| ropivacaine (local infiltration) NCT07704970 · QLESP Block for Pain Control in Robotic Partial Nephrectomy | Cancer | Traitement symptomatique · Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn if an ultrasound-guided nerve… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:54 | Détail |
| SL1CC Injection NCT07841002 · CLL-1-Targeted In Vivo CAR-T Cell Immunotherapy for Relapsed/Refractory Acute My… | Cancer | Immunomodulation · Thérapie cellulaire | Phase 1 | NOT_YET_RECRUITING | This is a single-center, open-label, single-arm, phase 1 dose-escalation s… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:54 | Détail |
| BH4, L-NMMA, Vitamin C, Vitamin E, α-Lipoic Acid and L-Ascorbate NCT02966665 · : Vascular Function in Health and Disease | Hypertension artérielle | Neuroprotection | Phase 1 | RECRUITING | Many control mechanisms exist which successfully match the supply of blood… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:47 | Détail |
| Lower Thoracic Spinal Cord Stimulation NCT07842315 · HTN-SCS — Spinal Cord Stimulation for Blood Pressure Control in Hypertension | Hypertension artérielle | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | High blood pressure, also called hypertension, raises the risk of heart di… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:47 | Détail |
| Lidocaine (drug) NCT07361549 · LIGHT 2 — Localized Injection of Lidocaine Via the Middle Meningeal Artery for H… | Migraine | Traitement symptomatique | Phase 2 | RECRUITING | The main purpose of this study is to evaluate the effectiveness of a new t… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:42 | Détail |
| Middle Meningeal Artery embolization NCT07652034 · EMBRACE-OBS: Single-Site Observational Registry of Patient-Reported Outcomes Fol… | Migraine | À vérifier | À vérifier | RECRUITING | This is a prospective, multi-center, feasibility study to investigate safe… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:37 | Détail |
| OnabotulinumtoxinA NCT07837570 · Comparison of the Effectiveness of Greater Occipital Nerve and Supratrochlear Ne… | Migraine | À vérifier | Phase 4 | NOT_YET_RECRUITING | Chronic migraine is a debilitating neurological disorder that significantl… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:37 | Détail |
| Ultrasound-guided pulsed radiofrequency (PRF) NCT07780136 · Effectiveness of Greater Occipital Nerve and Supratrochlear Nerve Pulsed Radiofr… | Migraine | Ralentissement de la progression · Traitement symptomatique · Thérapie génique | Phase 4 | NOT_YET_RECRUITING | Migraine is a common chronic neurovascular disorder ranked among the leadi… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:37 | Détail |
| BR005-036C NCT07835152 · Long-term Safety of BR005-036C Tablets in the Acute Treatment of Migraine in Adu… | Migraine | À vérifier | Phase 3 | NOT_YET_RECRUITING | The purpose of this study is to compare the efficacy and safety of BR005-0… À vérifier | ClinicalTrials.gov 2026-09-27 04:36:36 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effects of continuous vs. intermittent transcutaneous electrical stim… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 41866984 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source To compare the effects of two transcutaneous electrical stimulation (TES) patterns applied to the auricular branches of… | Cranio : the journal of craniomandibular practice 2026-11-08 04:38:07 | Source |
| Optimizing Percutaneous Tibial Nerve Stimulation Intensity for Overac… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42554545 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source Overactive bladder (OAB) is a significant global health issue. The standard percutaneous tibial nerve stimulation (PTNS… | Neuromodulation : journal of the International Neuromo… 2026-11-08 04:38:07 | Source |
| Transcutaneous auricular vagus nerve stimulation improves dysautonomi… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42802247 | Maladie rénale chronique | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Autonomic nervous system dysfunction is highly prevalent in hypermobile Ehlers-Danlos syndrome (hEDS) and contributes s… | Neurological sciences : official journal of the Italia… 2026-11-08 04:38:07 | Source |
| Factors associated with high-flow therapy failure in COVID-19-related… Non-Invasive Positive Pressure Ventilation · PMID 42888091 | Maladie rénale chronique | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source The optimal selection of non-invasive respiratory support for patients with COVID-19-related acute hypoxemic respirator… | Enfermedades infecciosas y microbiologia clinica (Engl… 2026-11-08 04:38:06 | Source |
| High-Flow Nasal Cannula in Adult Acute Care: Physiological Mechanisms… Non-Invasive Positive Pressure Ventilation · PMID 42942512 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source High-flow nasal cannula (HFNC) oxygen therapy is widely used in emergency, intensive care, perioperative, and procedura… | Medicina (Kaunas, Lithuania) 2026-11-08 04:38:06 | Source |
| Impact of respiratory support on time to achieve full oral feeding in… Non-Invasive Positive Pressure Ventilation · PMID 42871336 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source Very low birth weight infants often require respiratory support, which may delay full oral feeding. The independent rol… | Frontiers in pediatrics 2026-11-08 04:38:06 | Source |
| A comparative analysis of 3MAX aspiration versus 3 mm Trevo Retriever… Thromboaspiration catheter · PMID 31243066 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Although aspiration and stent retriever thrombectomy perform similarly in proximal occlusions, no comparative series ar… | Journal of neurointerventional surgery 2026-11-08 04:38:02 | Source |
| Percutaneous Pulmonary Thrombectomy Beyond Acute Pulmonary Embolism:… Thromboaspiration catheter · PMID 38385241 | Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Subacute massive pulmonary embolism is an uncommon manifestation of severe pulmonary embolism associated with poor prog… | Journal of endovascular therapy : an official journal… 2026-11-08 04:38:02 | Source |
| Simplified classification of cavernous internal carotid artery tortuo… Thromboaspiration catheter · PMID 35475775 | Hypertension artérielle · Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Thromboaspiration catheters are increasingly used for the endovascular treatment of large vessel stroke (LVS), while to… | Neurological research 2026-11-08 04:38:02 | Source |
| Multifocal continuous theta burst stimulation in idiopathic generaliz… Continuous Theta Burst Stimulation (cTBS) · PMID 42731195 | Accident vasculaire cérébral | Traitement symptomatique | Publication | PubMed | Voir la publication source Idiopathic generalized epilepsy (IGE) is a disorder of the cortico-subcortical networks. Continuous theta burst stimula… | Clinical neurophysiology : official journal of the Int… 2026-11-08 04:38:00 | Source |
| Optimizing brain functional-structural architecture with cTBS to redu… Continuous Theta Burst Stimulation (cTBS) · PMID 42457860 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Alcohol use disorder (AUD) is characterized by high relapse rates, necessitating novel interventions. Continuous theta-… | Molecular psychiatry 2026-11-08 04:38:00 | Source |
| Digital Outreach to Improve Statin Refills in Patients With Low Stati… Cordio System · PMID 42667613 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Statin nonadherence is a leading, addressable driver of preventable cardiovascular events. Although health systems rout… | JAMA 2026-11-08 04:37:54 | Source |
| Endovascular ablation of the right greater splanchnic nerve for the m… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42257781 | Insuffisance cardiaque | Traitement symptomatique | Publication | PubMed | Voir la publication source Heart failure with preserved ejection fraction (HFpEF) remains difficult to manage because conventional therapies often… | The Egyptian heart journal : (EHJ) : official bulletin… 2026-11-08 04:37:54 | Source |
| Incidence, medical therapy, and outcomes in heart failure with improv… Cordio System · PMID 42702264 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source To assess the incidence of heart failure with improved ejection fraction (HFimpEF) across guideline definitions (ACC/AH… | American heart journal 2026-11-08 04:37:54 | Source |
| Relationship Between the Azygos Vein and the Greater Splanchnic Nerve… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42249803 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Although ablation of the greater splanchnic nerve is now being used to treat some patients with heart failure, the anat… | Clinical anatomy (New York, N.Y.) 2026-11-08 04:37:54 | Source |
| Validation of the PREVENT-HF Risk Prediction Equation in US Veterans. Cordio System · PMID 42969140 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Circulation 2026-11-08 04:37:54 | Source |
| Changes in right ventricular-pulmonary artery coupling after transcat… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42822601 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Right ventricular-pulmonary artery (RV-PA) coupling is an established marker of prognosis in mitral regurgitation (MR),… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Intraprocedural evaluation of residual mitral and tricuspid regurgita… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42982241 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Transcatheter edge-to-edge repair (TEER) has emerged as an established therapeutic option for selected patients with se… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Tricuspid transcatheter edge-to-edge repair versus transcatheter tric… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42989943 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Recent clinical studies of tricuspid transcatheter edge-to-edge repair (T-TEER) and transcatheter tricuspid valve repla… | Current opinion in cardiology 2026-11-08 04:37:47 | Source |
| Automated Production of Gene-Edited CAR-T Cells for People Living wit… RAPA-501 Autologous T stem cells · PMID 42847201 | Cancer | Thérapie cellulaire · Thérapie génique | Publication | PubMed | Voir la publication source Adoptive transfer of gene-modified autologous T cells, for example, expressing chimeric antigen receptors (CARs), is a… | Human gene therapy 2026-11-08 04:37:39 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||