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Toutes les maladies
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
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10635 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 5743
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Dapagliflozin 10 MG Oral Tablet NCT07295223 · Effect of Glp-1 and Antidiabetic sgLT2 Agents for myoCardial infarcTion and Ultr… | Maladie coronarienne | Neuroprotection · Ralentissement de la progression · Immunomodulation · Traitem… | Phase 3 | COMPLETED | The primary risk factor for coronary artery disease is atherosclerosis, wi… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:43 | Détail |
| Early P2Y12 Inhibitor Monotherapy NCT07684742 · SAPT-ACS — Early Single Antiplatelet Therapy After IVUS-Guided PCI in Acute Coro… | Maladie coronarienne | À vérifier | Phase 4 | RECRUITING | This is a prospective, open-label, multicenter, randomized, phase IV clini… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:43 | Détail |
| Atrial flutter ablation NCT01521988 · PAF CRIOBLAF — Cryoballoon Pulmonary Venous Isolation in Patients Referred for T… | Maladie coronarienne | Traitement symptomatique | Non applicable | COMPLETED | \- Background: Atrial fibrillation is frequently associated with typical a… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:42 | Détail |
| Autologous Thymus Transplant NCT07799259 · ATTT — Autologous Thymus Transplant in Children With Congenital Heart Disease: A… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | This pilot study will look at whether putting back a child's own thymus ti… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:42 | Détail |
| Bimagrumab NCT07920887 · ACTIVATE-HFpEF — A Study of Bimagrumab in Participants With HFpEF | Maladie coronarienne | À vérifier | Phase 2 | NOT_YET_RECRUITING | This study will look at how bimagrumab affects adults who have a type of h… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:42 | Détail |
| F2 filter and delivery system NCT06689839 · SHIELD — Trial of the F2 Filter and Delivery System for Embolic Protection Durin… | Maladie coronarienne | Traitement symptomatique · Thérapie génique | Non applicable | RECRUITING | The goal of this clinical trial is to learn about the safety and performan… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:42 | Détail |
| FARAPULSE™ PFA system and WATCHMAN LAAC Delivery Systems NCT06686485 · OPTION-A — Concomitant Left Atrial Appendage Closure and Pulsed Field Ablation-A… | Maladie coronarienne | À vérifier | À vérifier | ACTIVE_NOT_RECRUITING | Subjects enrolled in the OPTION-A study will be clinically indicated for a… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:42 | Détail |
| Ferric derisomaltose NCT05971732 · The Effects of Ferric Derisomaltose in Patients With Acute Heart Failure and Iro… | Maladie coronarienne | À vérifier | Phase 4 | RECRUITING | This randomized, double-blind, placebo-controlled clinical trial evaluates… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:42 | Détail |
| nCPAP-NAVA-backup mode NCT07923604 · NAVAPNEA — nCPAP-NAVA-Backup Versus Standard nCPAP for Severe Apnea in Preterm I… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | The goal of this clinical trial is to determine whether nasal continuous p… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:42 | Détail |
| OPTIMIZER® Integra CCM-D System (Treatment Arm) NCT05855135 · INTEGRA-D — Assessment of Combined CCM and ICD Device in HFrEF | Maladie coronarienne | Traitement symptomatique | Non applicable | ACTIVE_NOT_RECRUITING | The goal of this clinical trial is to demonstrate that the OPTIMIZER® Inte… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:42 | Détail |
| Shockwave Balloon NCT05862558 · ILIT — Intravascular Lithotripsy in High Risk Calcified Iliac Anatomy for Transf… | Maladie coronarienne | Traitement symptomatique · Thérapie génique | À vérifier | ACTIVE_NOT_RECRUITING | To assess the efficacy and safety of Intravascular Lithotripsy (IVL) in su… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:42 | Détail |
| Smartphone simultaneous facial and fingertip photoplethysmography (re… NCT07922161 · Smartphone Camera Measurement of Breathing-Related Heart Rate Variability Compar… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | This study examines how accurately a smartphone can measure the rhythmic r… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:42 | Détail |
| Sphere-360 Pulsed Field Ablation Catheter with the Affera Mapping and… NCT07308847 · Horizon 360 Protocol for the Treatment of Paroxysmal Atrial Fibrillation With th… | Maladie coronarienne | À vérifier | Non applicable | ACTIVE_NOT_RECRUITING | The study is a prospective, single-arm, pre-market clinical study and will… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:42 | Détail |
| Tricuspid Transcatheter Edge-to-Edge Repair (TEER) NCT07586995 · TREAT TR — A Post-Market Assessment of the Safety and Performance of the TriClip… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | The objective of the TREAT TR study is to confirm the safety and performan… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:42 | Détail |
| Colchicine (Colcrys®) NCT07920133 · Hs-CRP-Guided Colchicine Treatment Targets in Very-High-Risk Patients With Coron… | Maladie coronarienne | Immunomodulation | Non applicable | NOT_YET_RECRUITING | This multicenter, randomized, open-label, noninferiority trial will compar… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:41 | Détail |
| Computed tomography coronary angiography (CTCA) NCT06234410 · CRAFT-CTCA — Cardiovascular Risk Assessment For Kidney Transplantation - Utility… | Maladie coronarienne | À vérifier | À vérifier | RECRUITING | Cardiovascular disease (for example, heart attack, stroke, heart failure)… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:41 | Détail |
| Orsiro Mission 48-mm Sirolimus-Eluting Coronary Stent System NCT06779630 · BIOFLOW-48 — Safety and Effectiveness of the Orsiro Mission 48-mm Sirolimus Elut… | Maladie coronarienne | À vérifier | Non applicable | RECRUITING | The purpose of the study is to assess the safety and efficacy of the Orsir… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:41 | Détail |
| Partial Cardiac Denervation NCT07918781 · CALM — Partial Cardiac Denervation for Preventing Atrial Fibrillation After CABG | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | Postoperative atrial fibrillation (POAF) is the most common arrhythmia fol… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:41 | Détail |
| SeQuent SCB sirolimus-coated balloon NCT07920055 · Sirolimus-Coated Versus Paclitaxel-Coated Balloon for Recurrent Coronary In-Sten… | Maladie coronarienne | À vérifier | Non applicable | NOT_YET_RECRUITING | This prospective, multicenter, randomized, open-label, noninferiority tria… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:41 | Détail |
| Vitamin D3 NCT02996721 · TARGET-D — A Trial Evaluating Vitamin D Normalization on Major Adverse Cardiovas… | Maladie coronarienne | À vérifier | Phase 4 | COMPLETED | A trial to measure the effects of vitamin D (versus a placebo) on balance,… À vérifier | ClinicalTrials.gov 2026-11-08 04:37:41 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4871
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effects of continuous vs. intermittent transcutaneous electrical stim… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 41866984 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source To compare the effects of two transcutaneous electrical stimulation (TES) patterns applied to the auricular branches of… | Cranio : the journal of craniomandibular practice 2026-11-08 04:38:07 | Source |
| Optimizing Percutaneous Tibial Nerve Stimulation Intensity for Overac… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42554545 | Maladie rénale chronique | Traitement symptomatique | Publication | PubMed | Voir la publication source Overactive bladder (OAB) is a significant global health issue. The standard percutaneous tibial nerve stimulation (PTNS… | Neuromodulation : journal of the International Neuromo… 2026-11-08 04:38:07 | Source |
| Transcutaneous auricular vagus nerve stimulation improves dysautonomi… Transcutaneous electrical nerve stimulation unit (TENS) · PMID 42802247 | Maladie rénale chronique | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Autonomic nervous system dysfunction is highly prevalent in hypermobile Ehlers-Danlos syndrome (hEDS) and contributes s… | Neurological sciences : official journal of the Italia… 2026-11-08 04:38:07 | Source |
| Factors associated with high-flow therapy failure in COVID-19-related… Non-Invasive Positive Pressure Ventilation · PMID 42888091 | Maladie rénale chronique | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source The optimal selection of non-invasive respiratory support for patients with COVID-19-related acute hypoxemic respirator… | Enfermedades infecciosas y microbiologia clinica (Engl… 2026-11-08 04:38:06 | Source |
| High-Flow Nasal Cannula in Adult Acute Care: Physiological Mechanisms… Non-Invasive Positive Pressure Ventilation · PMID 42942512 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source High-flow nasal cannula (HFNC) oxygen therapy is widely used in emergency, intensive care, perioperative, and procedura… | Medicina (Kaunas, Lithuania) 2026-11-08 04:38:06 | Source |
| Impact of respiratory support on time to achieve full oral feeding in… Non-Invasive Positive Pressure Ventilation · PMID 42871336 | Maladie rénale chronique | À vérifier | Publication | PubMed | Voir la publication source Very low birth weight infants often require respiratory support, which may delay full oral feeding. The independent rol… | Frontiers in pediatrics 2026-11-08 04:38:06 | Source |
| A comparative analysis of 3MAX aspiration versus 3 mm Trevo Retriever… Thromboaspiration catheter · PMID 31243066 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Although aspiration and stent retriever thrombectomy perform similarly in proximal occlusions, no comparative series ar… | Journal of neurointerventional surgery 2026-11-08 04:38:02 | Source |
| Percutaneous Pulmonary Thrombectomy Beyond Acute Pulmonary Embolism:… Thromboaspiration catheter · PMID 38385241 | Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Subacute massive pulmonary embolism is an uncommon manifestation of severe pulmonary embolism associated with poor prog… | Journal of endovascular therapy : an official journal… 2026-11-08 04:38:02 | Source |
| Simplified classification of cavernous internal carotid artery tortuo… Thromboaspiration catheter · PMID 35475775 | Hypertension artérielle · Accident vasculaire cérébral | Thérapie génique | Publication | PubMed | Voir la publication source Thromboaspiration catheters are increasingly used for the endovascular treatment of large vessel stroke (LVS), while to… | Neurological research 2026-11-08 04:38:02 | Source |
| Multifocal continuous theta burst stimulation in idiopathic generaliz… Continuous Theta Burst Stimulation (cTBS) · PMID 42731195 | Accident vasculaire cérébral | Traitement symptomatique | Publication | PubMed | Voir la publication source Idiopathic generalized epilepsy (IGE) is a disorder of the cortico-subcortical networks. Continuous theta burst stimula… | Clinical neurophysiology : official journal of the Int… 2026-11-08 04:38:00 | Source |
| Optimizing brain functional-structural architecture with cTBS to redu… Continuous Theta Burst Stimulation (cTBS) · PMID 42457860 | Accident vasculaire cérébral | À vérifier | Publication | PubMed | Voir la publication source Alcohol use disorder (AUD) is characterized by high relapse rates, necessitating novel interventions. Continuous theta-… | Molecular psychiatry 2026-11-08 04:38:00 | Source |
| Digital Outreach to Improve Statin Refills in Patients With Low Stati… Cordio System · PMID 42667613 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Statin nonadherence is a leading, addressable driver of preventable cardiovascular events. Although health systems rout… | JAMA 2026-11-08 04:37:54 | Source |
| Endovascular ablation of the right greater splanchnic nerve for the m… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42257781 | Insuffisance cardiaque | Traitement symptomatique | Publication | PubMed | Voir la publication source Heart failure with preserved ejection fraction (HFpEF) remains difficult to manage because conventional therapies often… | The Egyptian heart journal : (EHJ) : official bulletin… 2026-11-08 04:37:54 | Source |
| Incidence, medical therapy, and outcomes in heart failure with improv… Cordio System · PMID 42702264 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source To assess the incidence of heart failure with improved ejection fraction (HFimpEF) across guideline definitions (ACC/AH… | American heart journal 2026-11-08 04:37:54 | Source |
| Relationship Between the Azygos Vein and the Greater Splanchnic Nerve… Right Greater Splanchnic Nerve (GSN) ablation · PMID 42249803 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Although ablation of the greater splanchnic nerve is now being used to treat some patients with heart failure, the anat… | Clinical anatomy (New York, N.Y.) 2026-11-08 04:37:54 | Source |
| Validation of the PREVENT-HF Risk Prediction Equation in US Veterans. Cordio System · PMID 42969140 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Circulation 2026-11-08 04:37:54 | Source |
| Changes in right ventricular-pulmonary artery coupling after transcat… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42822601 | Insuffisance cardiaque | À vérifier | Publication | PubMed | Voir la publication source Right ventricular-pulmonary artery (RV-PA) coupling is an established marker of prognosis in mitral regurgitation (MR),… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Intraprocedural evaluation of residual mitral and tricuspid regurgita… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42982241 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Transcatheter edge-to-edge repair (TEER) has emerged as an established therapeutic option for selected patients with se… | International journal of cardiology 2026-11-08 04:37:47 | Source |
| Tricuspid transcatheter edge-to-edge repair versus transcatheter tric… Tricuspid Transcatheter Edge-to-Edge Repair (TEER) · PMID 42989943 | Maladie coronarienne | À vérifier | Publication | PubMed | Voir la publication source Recent clinical studies of tricuspid transcatheter edge-to-edge repair (T-TEER) and transcatheter tricuspid valve repla… | Current opinion in cardiology 2026-11-08 04:37:47 | Source |
| Automated Production of Gene-Edited CAR-T Cells for People Living wit… RAPA-501 Autologous T stem cells · PMID 42847201 | Cancer | Thérapie cellulaire · Thérapie génique | Publication | PubMed | Voir la publication source Adoptive transfer of gene-modified autologous T cells, for example, expressing chimeric antigen receptors (CARs), is a… | Human gene therapy 2026-11-08 04:37:39 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||